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Volumn 22, Issue 5, 2008, Pages 494-501
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Validation of a fully automated high throughput liquid chromatographic/tandem mass spectrometric method for roxithromycin quantification in human plasma. Application to a bioequivalence study
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Author keywords
96 well; Bioequivalence; Electrospray; Roxithromycin; Validation
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Indexed keywords
DRUG PRODUCTS;
ELECTROSPRAY IONIZATION;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
PLASMA (HUMAN);
POSITIVE IONS;
THROUGHPUT;
96-WELL;
BIOEQUIVALENCE;
BIOEQUIVALENCE STUDY;
ELECTROSPRAYS;
FULLY AUTOMATED;
HIGH-THROUGHPUT;
HUMAN PLASMAS;
LIQUID-LIQUID EXTRACTION;
ROXITHROMYCIN;
VALIDATION;
ORGANIC SOLVENTS;
CLARITHROMYCIN;
ROXITHROMYCIN;
TERT BUTYL METHYL ETHER;
ACCURACY;
AREA UNDER THE CURVE;
ARTICLE;
AUTOMATION;
BIOEQUIVALENCE;
CALIBRATION;
CENTRIFUGATION;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG ELIMINATION;
DRUG HALF LIFE;
DRUG ISOLATION;
EVAPORATION;
FREEZING;
HIGH THROUGHPUT SCREENING;
HUMAN;
HUMAN EXPERIMENT;
LIQUID LIQUID EXTRACTION;
MAXIMUM PLASMA CONCENTRATION;
NORMAL HUMAN;
POSITIVE ION ELECTROSPRAY;
PROCESS DEVELOPMENT;
QUANTITATIVE ANALYSIS;
RELIABILITY;
REPRODUCIBILITY;
REVERSED PHASE LIQUID CHROMATOGRAPHY;
ROBOTICS;
SUPERNATANT;
TANDEM MASS SPECTROMETRY;
VALIDATION PROCESS;
VOLUNTEER;
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EID: 44249089515
PISSN: 02693879
EISSN: 10990801
Source Type: Journal
DOI: 10.1002/bmc.958 Document Type: Article |
Times cited : (13)
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References (22)
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