Development of a μ-turbulent flow chromatography focus mode method for drug quantitation in discovery bioanalysis

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 856, Issue 1-2, 2007, Pages 131-140

  Turnpenny, Paul ^a   Fraier, Daniela ^a   Chassaing, Christophe ^a   Duckworth, Jonathan ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Analytical column; Biological matrices; Focus mode; Low volume samples; Online extraction; Tandem mass spectrometry; Turbulent flow chromatography (TFC)

Indexed keywords

BIOACTIVITY; BIOLOGICAL MATERIALS; CONCENTRATION (PROCESS); DRUG PRODUCTS; MASS SPECTROMETRY; NANOSTRUCTURED MATERIALS;

ANALYTICAL COLUMN; BIOLOGICAL MATRICES; FOCUS MODE; LOW VOLUME SAMPLES; ONLINE EXTRACTION; TANDEM MASS SPECTROMETRY; TURBULENT FLOW CHROMATOGRAPHY (TFC);

LIQUID CHROMATOGRAPHY;

CANDOXATRIL; DOFETILIDE; FLUCONAZOLE; DRUG;

ACCURACY; ACIDITY; ALKALINITY; ARTICLE; COLUMN CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); DRUG DETERMINATION; EXTRACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; TANDEM MASS SPECTROMETRY; TURBULENT FLOW; TURBULENT FLOW CHROMATOGRAPHY; VALIDATION STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; STANDARD;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; PHARMACEUTICAL PREPARATIONS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 34548188284     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.05.032     Document Type: Article

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