Development of a rapid and sensitive LC-MS/MS assay for the determination of sorafenib in human plasma

Journal of Pharmaceutical and Biomedical Analysis

Volumn 46, Issue 2, 2008, Pages 362-367

  Jain, Lokesh ^a,b   Gardner, Erin R ^c   Venitz, Jürgen ^a   Dahut, William ^b   Figg, William D ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

Author keywords

BAY43 9006; Kinase inhibitor

Indexed keywords

ACETONITRILE; FORMIC ACID; SORAFENIB; WATER;

ACCURACY; ARTICLE; DRUG DETERMINATION; HUMAN; LIQUID CHROMATOGRAPHY; PLASMA; POSITIVE ION ELECTROSPRAY; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ASSAY; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY;

BENZENESULFONATES; CALIBRATION; HUMANS; PROTEIN KINASE INHIBITORS; PYRIDINES; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 37749052511     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2007.10.027     Document Type: Article

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