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Volumn 23, Issue 6, 2009, Pages 623-629
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Liquid chromatographic/mass spectrometry assay of bromotetrandrine in rat plasma and its application to pharmacokinetic study
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Author keywords
Bromotetrandrine; LC MS MS; Pharmacokinetics
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Indexed keywords
BODY FLUIDS;
HEXANE;
LIQUID CHROMATOGRAPHY;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
RATS;
BROMOTETRANDRINE;
INTERNAL STANDARDS;
ITS APPLICATIONS;
LC-MS-MS;
LC.MS/MS;
ORAL ADMINISTRATION;
PHARMACOKINETIC STUDIES;
RAT PLASMA;
SPRAGUE-DAWLEY RATS;
TANDEM MASS SPECTROMETRIC;
PHARMACOKINETICS;
2 PROPANOL;
AMMONIUM FORMATE;
BRODIMOPRIM;
BROMOTETRANDRINE;
DICHLOROMETHANE;
FORMIC ACID;
HEXANE;
METHANOL;
TETRANDRINE;
UNCLASSIFIED DRUG;
BENZYLISOQUINOLINE DERIVATIVE;
N-HEXANE;
ACCURACY;
ANIMAL EXPERIMENT;
AQUEOUS SOLUTION;
AREA UNDER THE CURVE;
ARTICLE;
BLOOD SAMPLING;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG ELIMINATION;
DRUG HALF LIFE;
DRUG STABILITY;
DRUG STRUCTURE;
ELECTROSPRAY MASS SPECTROMETRY;
FEMALE;
IONIZATION;
LIQUID CHROMATOGRAPHY;
LIQUID LIQUID EXTRACTION;
MALE;
MASS SPECTROMETER;
MAXIMUM PLASMA CONCENTRATION;
NONHUMAN;
QUALITY CONTROL;
RAT;
SEPARATION TECHNIQUE;
SINGLE DRUG DOSE;
SPRAGUE DAWLEY RAT;
TIME TO MAXIMUM PLASMA CONCENTRATION;
ANIMAL;
BLOOD;
CHEMISTRY;
ECONOMICS;
MASS SPECTROMETRY;
METHODOLOGY;
SENSITIVITY AND SPECIFICITY;
STATISTICAL MODEL;
TIME;
VALIDATION STUDY;
RATTUS;
ANIMALS;
BENZYLISOQUINOLINES;
CHROMATOGRAPHY, LIQUID;
FEMALE;
HEXANES;
LINEAR MODELS;
MALE;
MASS SPECTROMETRY;
METHYLENE CHLORIDE;
RATS;
RATS, SPRAGUE-DAWLEY;
SENSITIVITY AND SPECIFICITY;
TIME FACTORS;
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EID: 67651206064
PISSN: 02693879
EISSN: 10990801
Source Type: Journal
DOI: 10.1002/bmc.1163 Document Type: Article |
Times cited : (4)
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References (6)
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