Comparison of turbulent-flow chromatography with automated solid-phase extraction in 96-well plates and liquid-liquid extraction used as plasma sample preparation techniques for liquid chromatography-tandem mass spectrometry

Journal of Chromatography A

Volumn 854, Issue 1-2, 1999, Pages 23-35

  Zimmer, Dieter ^a   Pickard, Volker ^a   Czembor, Waldemar ^a   Müller, Christoph ^a  

^a BAYER AG   (Germany)

Author keywords

Pharmaceutical analysis; Sample preparation; Turbulent flow chromatography; Validation

Indexed keywords

ACCURACY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DETERMINATION; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; SAMPLING; SOLID PHASE EXTRACTION; TURBULENT FLOW; VALIDATION PROCESS; WORKLOAD;

ANIMALS; AUTOMATION; BLOOD CHEMICAL ANALYSIS; CHROMATOGRAPHY, LIQUID; DOGS; MASS SPECTROMETRY; PHARMACOKINETICS; RATS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

CANIS FAMILIARIS;

EID: 0032767701     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(99)00535-X     Document Type: Conference Paper

References (6)

1. D. Zimmer, W. Czembor, V. Pickard, 1996, unpublished results.
2. Pretorius V., Smuts T. Anal. Chem. 38:1966;274-280.
3. H.M. Quinn, J.J. Takarewski, Int. Pat. WO 97/16724 (1997).
4. Ayrton J., Dear G.J., Leavens W.J., Mallett D.N., Plumb R.S. Rapid Commun. Mass Spectrom. 11:1997;1953-1958.
5. Allanson J., Biddlecombe R.A., Jones A.E., Pleasance S. Rapid Commun. Mass Spectrom. 10:1996;811-816.
6. Concalc Software version 1.23, Bayer, Wuppertal, Germany, 1995.