Identification and control of impurities for drug substance development using LC/MS and GC/MS

Journal of Liquid Chromatography and Related Technologies

Volumn 31, Issue 15, 2008, Pages 2235-2252

  Lee, Heewon ^a   Shen, Sherry ^a   Grinberg, Nelu ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

Control of impurities; Drug development; GC MS; LC MS

Indexed keywords

CHEMOTHERAPY; CHROMATOGRAPHIC ANALYSIS; DRUG DELIVERY; DRUG DOSAGE; DRUG PRODUCTS; DRUG PRODUCTS PLANTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IDENTIFICATION (CONTROL SYSTEMS); LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

ANALYTICAL TECHNIQUES; CASE STUDIES; CHEMICAL-; CHROMATOGRAPHIC TECHNIQUES; CONTROL OF IMPURITIES; DRUG DEVELOPMENT; DRUG SUBSTANCES; GC/MS; HIGH RESOLUTION MASS SPECTROMETRY; IMPURITY PROFILING; LC/MS; PHARMACEUTICAL PROCESS DEVELOPMENT; PREPARATIVE HPLC; TANDEM MASS SPECTROMETRY;

IMPURITIES;

ARTICLE; DRUG IMPURITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY;

EID: 49449098180     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070802279426     Document Type: Article

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