Determination of levocetirizine in human plasma by liquid chromatography-electrospray tandem mass spectrometry: Application to a bioequivalence study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 862, Issue 1-2, 2008, Pages 132-139

  Morita, M R ^a,c   Berton, D ^a   Boldin, R ^a   Barros, F A P ^a   Meurer, E C ^a   Amarante, A R ^b   Campos, D R ^c   Calafatti, S A ^a   Pereira, R ^b   Abib Jr , E ^b,c   Pedrazolli Jr , J ^a,c  

^a Core Clinical Research ^*  (Brazil)

^b Scentryphar Clinical Research   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Bioavailability; Levocetirizine; Mass spectrometry

Indexed keywords

LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

BIOAVAILABILITY; LEVOCETIRIZINE; SELECTED REACTION MONITORING;

PLASMA (HUMAN);

ACETONITRILE; DICHLOROMETHANE; FEXOFENADINE; FORMIC ACID; LEVOCETIRIZINE; WATER;

ACCURACY; ADULT; ARTICLE; BIOEQUIVALENCE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG STRUCTURE; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; NORMAL HUMAN; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ADOLESCENT; ADULT; BIOLOGICAL AVAILABILITY; CETIRIZINE; CROSS-OVER STUDIES; HISTAMINE H1 ANTAGONISTS; HUMANS; MIDDLE AGED; PIPERAZINES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THERAPEUTIC EQUIVALENCY;

EID: 38649137277     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.11.028     Document Type: Article

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