Reduction of in-source collision-induced dissociation and thermolysis of sulopenem prodrugs for quantitative liquid chromatography/electrospray ionization mass spectrometric analysis by promoting sodium adduct formation

Rapid Communications in Mass Spectrometry

Volumn 22, Issue 20, 2008, Pages 3195-3206

  Wujcik, Chad E ^a   Kadar, Eugene P ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; DISSOCIATION; IONS; LIQUID CHROMATOGRAPHY; SODIUM;

% REDUCTIONS; ADDUCT ION; DECLUSTERING; IN-SOURCE COLLISION-INDUCED DISSOCIATIONS; LIQUID CHROMATOGRAPHY ELECTROSPRAY; MOBILE PHASIS; NA+ IONS; PRODRUGS; SODIUM ADDUCTS; THERMOLYSES;

MASS SPECTROMETRY;

ANTIINFECTIVE AGENT; LACTAM; PRODRUG; SODIUM; SULOPENEM;

ARTICLE; BLOOD; CALIBRATION; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; QUALITY CONTROL; STANDARD; TEMPERATURE; THERMODYNAMICS;

ANTI-BACTERIAL AGENTS; CALIBRATION; HUMANS; LACTAMS; PRODRUGS; QUALITY CONTROL; REFERENCE STANDARDS; SODIUM; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TEMPERATURE; THERMODYNAMICS;

EID: 58149179547     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.3722     Document Type: Article

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