Matrix effects during analysis of plasma samples by electrospray and atmospheric pressure chemical ionization mass spectrometry: Practical approaches to their elimination

Rapid Communications in Mass Spectrometry

Volumn 17, Issue 17, 2003, Pages 1950-1957

  Schuhmacher, Joachim ^a,b   Zimmer, Dieter ^a   Tesche, Frank ^a   Pickard, Volker ^a  

^a BAYER PHARMA AG   (Germany)

^b BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATMOSPHERIC CHEMISTRY; ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; IONS; MASS SPECTROMETRY; QUALITY CONTROL;

ATMOSPHERIC PRESSURE CHEMICAL IONIZATION; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION MASS SPECTROMETRY; ELECTROSPRAYS; ION SUPPRESSION; IONIZATION TECHNIQUES; MATRICES EFFECT; PHARMACOKINETIC PARAMETERS; PLASMA CONCENTRATION; PLASMA SAMPLES; TURBOIONSPRAY;

PROTEINS;

ALCOHOL; DRUG; MACROGOL 400; PLASMA PROTEIN;

ANALYTICAL ERROR; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; ATMOSPHERIC PRESSURE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG FORMULATION; MALE; MASS SPECTROMETRY; NONHUMAN; PLASMA; PRECIPITATION; PROTEIN BLOOD LEVEL; QUALITY CONTROL; RAT; SAMPLING; THERMOSTABILITY; VALIDATION PROCESS;

EID: 0041425212     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.1139     Document Type: Article

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