-
1
-
-
0001408917
-
One-trial object recognition by rats
-
Aggleton J.P. One-trial object recognition by rats. Q. J. Exp. Psychol. 1985, 37:279-294.
-
(1985)
Q. J. Exp. Psychol.
, vol.37
, pp. 279-294
-
-
Aggleton, J.P.1
-
2
-
-
0032801549
-
Episodic memory, amnesia, and the hippocampal-anterior thalamic axis
-
discussion 444-489
-
Aggleton J.P., Brown M.W. Episodic memory, amnesia, and the hippocampal-anterior thalamic axis. Behav. Brain Sci. 1999, 22:425-444. discussion 444-489.
-
(1999)
Behav. Brain Sci.
, vol.22
, pp. 425-444
-
-
Aggleton, J.P.1
Brown, M.W.2
-
4
-
-
0035830686
-
Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
-
Arendash G.W., King D.L., Gordon M.N., Morgan D., Hatcher J.M., Hope C.E., Diamond D.M. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. Brain Res. 2001, 891:42-53.
-
(2001)
Brain Res.
, vol.891
, pp. 42-53
-
-
Arendash, G.W.1
King, D.L.2
Gordon, M.N.3
Morgan, D.4
Hatcher, J.M.5
Hope, C.E.6
Diamond, D.M.7
-
5
-
-
0035689651
-
Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: task specificity and correlations between Abeta deposition and spatial memory
-
Arendash G.W., Gordon M.N., Diamond D.M., Austin L.A., Hatcher J.M., Jantzen P., DiCarlo G., Wilcock D., Morgan D. Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: task specificity and correlations between Abeta deposition and spatial memory. DNA Cell Biol. 2001, 20:737-744.
-
(2001)
DNA Cell Biol.
, vol.20
, pp. 737-744
-
-
Arendash, G.W.1
Gordon, M.N.2
Diamond, D.M.3
Austin, L.A.4
Hatcher, J.M.5
Jantzen, P.6
DiCarlo, G.7
Wilcock, D.8
Morgan, D.9
-
6
-
-
67349213205
-
Synaptic degeneration in Alzheimer's disease
-
Arendt T. Synaptic degeneration in Alzheimer's disease. Acta Neuropathol. 2009, 118:167-179.
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 167-179
-
-
Arendt, T.1
-
7
-
-
33750905657
-
Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages
-
Asuni A.A., Boutajangout A., Scholtzova H., Knudsen E., Li Y.S., Quartermain D., Frangione B., Wisniewski T., Sigurdsson E.M. Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages. Eur. J. Neurosci. 2006, 24:2530-2542.
-
(2006)
Eur. J. Neurosci.
, vol.24
, pp. 2530-2542
-
-
Asuni, A.A.1
Boutajangout, A.2
Scholtzova, H.3
Knudsen, E.4
Li, Y.S.5
Quartermain, D.6
Frangione, B.7
Wisniewski, T.8
Sigurdsson, E.M.9
-
8
-
-
0038240645
-
Short-term beta-amyloid vaccinations do not improve cognitive performance in cognitively impaired APP+PS1 mice
-
Austin L., Arendash G.W., Gordon M.N., Diamond D.M., DiCarlo G., Dickey C., Ugen K., Morgan D. Short-term beta-amyloid vaccinations do not improve cognitive performance in cognitively impaired APP+PS1 mice. Behav. Neurosci. 2003, 117:478-484.
-
(2003)
Behav. Neurosci.
, vol.117
, pp. 478-484
-
-
Austin, L.1
Arendash, G.W.2
Gordon, M.N.3
Diamond, D.M.4
DiCarlo, G.5
Dickey, C.6
Ugen, K.7
Morgan, D.8
-
9
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F., Cannon C., Barbour R., Burke R.L., Games D., Grajeda H., Guido T., Hu K., Huang J., Johnson-Wood K., Khan K., Kholodenko D., Lee M., Lieberburg I., Motter R., Nguyen M., Soriano F., Vasquez N., Weiss K., Welch B., Seubert P., Schenk D., Yednock T. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat. Med. 2000, 6:916-919.
-
(2000)
Nat. Med.
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, M.13
Lieberburg, I.14
Motter, R.15
Nguyen, M.16
Soriano, F.17
Vasquez, N.18
Weiss, K.19
Welch, B.20
Seubert, P.21
Schenk, D.22
Yednock, T.23
more..
-
10
-
-
0018344553
-
Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat
-
Barnes C.A. Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J. Comp. Physiol. Psychol. 1979, 93:74-104.
-
(1979)
J. Comp. Physiol. Psychol.
, vol.93
, pp. 74-104
-
-
Barnes, C.A.1
-
11
-
-
58149307496
-
Combinatorial treatments including vaccines, chemotherapy and monoclonal antibodies for cancer therapy
-
Baxevanis C.N., Perez S.A., Papamichail M. Combinatorial treatments including vaccines, chemotherapy and monoclonal antibodies for cancer therapy. Cancer Immunol. Immunother. 2009, 58:317-324.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 317-324
-
-
Baxevanis, C.N.1
Perez, S.A.2
Papamichail, M.3
-
12
-
-
33747886054
-
The object recognition task in rats and mice: a simple and rapid model in safety pharmacology to detect amnesic properties of a new chemical entity
-
Bertaina-Anglade V., Enjuanes E., Morillon D., Drieu L.R. The object recognition task in rats and mice: a simple and rapid model in safety pharmacology to detect amnesic properties of a new chemical entity. J. Pharmacol. Toxicol. Methods 2006, 54(2):99-105.
-
(2006)
J. Pharmacol. Toxicol. Methods
, vol.54
, Issue.2
, pp. 99-105
-
-
Bertaina-Anglade, V.1
Enjuanes, E.2
Morillon, D.3
Drieu, L.R.4
-
13
-
-
34347215149
-
Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'
-
Bevins R.A., Besheer J. Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'. Nat. Protoc. 2006, 1:1306-1311.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 1306-1311
-
-
Bevins, R.A.1
Besheer, J.2
-
14
-
-
14644442872
-
Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
-
Billings L.M., Oddo S., Green K.N., McGaugh J.L., LaFerla F.M. Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron 2005, 45:675-688.
-
(2005)
Neuron
, vol.45
, pp. 675-688
-
-
Billings, L.M.1
Oddo, S.2
Green, K.N.3
McGaugh, J.L.4
LaFerla, F.M.5
-
15
-
-
47949132196
-
Active and passive immunotherapy for neurodegenerative disorders
-
Brody D.L., Holtzman D.M. Active and passive immunotherapy for neurodegenerative disorders. Annu. Rev. Neurosci. 2008.
-
(2008)
Annu. Rev. Neurosci.
-
-
Brody, D.L.1
Holtzman, D.M.2
-
16
-
-
33847776041
-
Active beta-amyloid immunization restores spatial learning in PDAPP mice displaying very low levels of beta-amyloid
-
Chen G., Chen K.S., Kobayashi D., Barbour R., Motter R., Games D., Martin S.J., Morris R.G. Active beta-amyloid immunization restores spatial learning in PDAPP mice displaying very low levels of beta-amyloid. J. Neurosci. 2007, 27:2654-2662.
-
(2007)
J. Neurosci.
, vol.27
, pp. 2654-2662
-
-
Chen, G.1
Chen, K.S.2
Kobayashi, D.3
Barbour, R.4
Motter, R.5
Games, D.6
Martin, S.J.7
Morris, R.G.8
-
17
-
-
9144272296
-
Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation
-
Cheng I.H., Palop J.J., Esposito L.A., Bien-Ly N., Yan F., Mucke L. Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation. Nat. Med. 2004, 10:1190-1192.
-
(2004)
Nat. Med.
, vol.10
, pp. 1190-1192
-
-
Cheng, I.H.1
Palop, J.J.2
Esposito, L.A.3
Bien-Ly, N.4
Yan, F.5
Mucke, L.6
-
18
-
-
0035877756
-
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
-
Chishti M.A., Yang D.S., Janus C., Phinney A.L., Horne P., Pearson J., Strome R., Zuker N., Loukides J., French J., Turner S., Lozza G., Grilli M., Kunicki S., Morissette C., Paquette J., Gervais F., Bergeron C., Fraser P.E., Carlson G.A., George-Hyslop P.S., Westaway D. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J. Biol. Chem. 2001, 276:21562-21570.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.S.2
Janus, C.3
Phinney, A.L.4
Horne, P.5
Pearson, J.6
Strome, R.7
Zuker, N.8
Loukides, J.9
French, J.10
Turner, S.11
Lozza, G.12
Grilli, M.13
Kunicki, S.14
Morissette, C.15
Paquette, J.16
Gervais, F.17
Bergeron, C.18
Fraser, P.E.19
Carlson, G.A.20
George-Hyslop, P.S.21
Westaway, D.22
more..
-
20
-
-
35848962080
-
Disease-modifying therapies for Alzheimer disease: challenges to early intervention
-
Cummings J.L., Doody R., Clark C. Disease-modifying therapies for Alzheimer disease: challenges to early intervention. Neurology 2007, 69:1622-1634.
-
(2007)
Neurology
, vol.69
, pp. 1622-1634
-
-
Cummings, J.L.1
Doody, R.2
Clark, C.3
-
21
-
-
34250630141
-
Appetitive position discrimination in the T-maze
-
Deacon R.M. Appetitive position discrimination in the T-maze. Nat. Protoc. 2006, 1:13-15.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 13-15
-
-
Deacon, R.M.1
-
22
-
-
44949133037
-
Vaccination with cytokines in autoimmune diseases
-
Delavallee L., Assier E., Denys A., Falgarone G., Zagury J.F., Muller S., Bessis N., Boissier M.C. Vaccination with cytokines in autoimmune diseases. Ann. Med. 2008, 40:343-351.
-
(2008)
Ann. Med.
, vol.40
, pp. 343-351
-
-
Delavallee, L.1
Assier, E.2
Denys, A.3
Falgarone, G.4
Zagury, J.F.5
Muller, S.6
Bessis, N.7
Boissier, M.C.8
-
23
-
-
0035902619
-
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
-
DeMattos R.B., Bales K.R., Cummins D.J., Dodart J.C., Paul S.M., Holtzman D.M. Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:8850-8855.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 8850-8855
-
-
DeMattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Dodart, J.C.4
Paul, S.M.5
Holtzman, D.M.6
-
24
-
-
34247574175
-
The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents
-
Dere E., Huston J.P., Souza Silva M.A. The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents. Neurosci. Biobehav. Rev. 2007, 31:673-704.
-
(2007)
Neurosci. Biobehav. Rev.
, vol.31
, pp. 673-704
-
-
Dere, E.1
Huston, J.P.2
Souza Silva, M.A.3
-
25
-
-
0030660554
-
Neuropathological diagnosis of Alzheimer's disease: a perspective from longitudinal clinicopathological studies
-
Dickson D.W. Neuropathological diagnosis of Alzheimer's disease: a perspective from longitudinal clinicopathological studies. Neurobiol. Aging 1997, 18:S21-S26.
-
(1997)
Neurobiol. Aging
, vol.18
-
-
Dickson, D.W.1
-
26
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
-
Dodart J.C., Bales K.R., Gannon K.S., Greene S.J., DeMattos R.B., Mathis C., DeLong C.A., Wu S., Wu X., Holtzman D.M., Paul S.M. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. Nat. Neurosci. 2002, 5:452-457.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 452-457
-
-
Dodart, J.C.1
Bales, K.R.2
Gannon, K.S.3
Greene, S.J.4
DeMattos, R.B.5
Mathis, C.6
DeLong, C.A.7
Wu, S.8
Wu, X.9
Holtzman, D.M.10
Paul, S.M.11
-
27
-
-
0023691166
-
A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data
-
Ennaceur A., Delacour J. A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data. Behav. Brain Res. 1988, 31:47-59.
-
(1988)
Behav. Brain Res.
, vol.31
, pp. 47-59
-
-
Ennaceur, A.1
Delacour, J.2
-
28
-
-
33846466652
-
Plaques, tangles, and memory loss in mouse models of neurodegeneration
-
Eriksen J.L., Janus C.G. Plaques, tangles, and memory loss in mouse models of neurodegeneration. Behav. Genet. 2007, 37:79-100.
-
(2007)
Behav. Genet.
, vol.37
, pp. 79-100
-
-
Eriksen, J.L.1
Janus, C.G.2
-
29
-
-
0032976615
-
The neuroanatomical and neurochemical basis of conditioned fear
-
Fendt M., Fanselow M.S. The neuroanatomical and neurochemical basis of conditioned fear. Neurosci. Biobehav. Rev. 1999, 23:743-760.
-
(1999)
Neurosci. Biobehav. Rev.
, vol.23
, pp. 743-760
-
-
Fendt, M.1
Fanselow, M.S.2
-
30
-
-
42549089024
-
Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4
-
Frazer M.E., Hughes J.E., Mastrangelo M.A., Tibbens J.L., Federoff H.J., Bowers W.J. Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4. Mol. Ther. 2008, 16:845-853.
-
(2008)
Mol. Ther.
, vol.16
, pp. 845-853
-
-
Frazer, M.E.1
Hughes, J.E.2
Mastrangelo, M.A.3
Tibbens, J.L.4
Federoff, H.J.5
Bowers, W.J.6
-
31
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., Gillespie F. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 1995, 373:523-527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
-
32
-
-
20944448555
-
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial
-
Gilman S., Koller M., Black R.S., Jenkins L., Griffith S.G., Fox N.C., Eisner L., Kirby L., Rovira M.B., Forette F., Orgogozo J.M. Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial. Neurology 2005, 64:1553-1562.
-
(2005)
Neurology
, vol.64
, pp. 1553-1562
-
-
Gilman, S.1
Koller, M.2
Black, R.S.3
Jenkins, L.4
Griffith, S.G.5
Fox, N.C.6
Eisner, L.7
Kirby, L.8
Rovira, M.B.9
Forette, F.10
Orgogozo, J.M.11
-
33
-
-
45749151056
-
Animal models of Alzheimer's disease and frontotemporal dementia
-
Götz J., Ittner L.M. Animal models of Alzheimer's disease and frontotemporal dementia. Nat. Rev. Neurosci. 2008, 9:532-544.
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, pp. 532-544
-
-
Götz, J.1
Ittner, L.M.2
-
34
-
-
48749101427
-
Early deficits in motor coordination and cognitive dysfunction in a mouse model of the neurodegenerative lysosomal storage disorder, Sandhoff disease
-
Gulinello M., Chen F., Dobrenis K. Early deficits in motor coordination and cognitive dysfunction in a mouse model of the neurodegenerative lysosomal storage disorder, Sandhoff disease. Behav. Brain Res. 2008, 193(2):315-319.
-
(2008)
Behav. Brain Res.
, vol.193
, Issue.2
, pp. 315-319
-
-
Gulinello, M.1
Chen, F.2
Dobrenis, K.3
-
35
-
-
0033009194
-
Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation
-
Guo Q., Sebastian L., Sopher B.L., Miller M.W., Ware C.B., Martin G.M., Mattson M.P. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation. J. Neurochem. 1999, 72:1019-1029.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1019-1029
-
-
Guo, Q.1
Sebastian, L.2
Sopher, B.L.3
Miller, M.W.4
Ware, C.B.5
Martin, G.M.6
Mattson, M.P.7
-
36
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide
-
Haass C., Selkoe D.J. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat. Rev. Mol. Cell Biol. 2007, 8:101-112.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
37
-
-
14244252864
-
Development of a safe oral Abeta vaccine using recombinant adeno-associated virus vector for Alzheimer's disease
-
Hara H., Monsonego A., Yuasa K., Adachi K., Xiao X., Takeda S., Takahashi K., Weiner H.L., Tabira T. Development of a safe oral Abeta vaccine using recombinant adeno-associated virus vector for Alzheimer's disease. J. Alzheimers Dis. 2004, 6:483-488.
-
(2004)
J. Alzheimers Dis.
, vol.6
, pp. 483-488
-
-
Hara, H.1
Monsonego, A.2
Yuasa, K.3
Adachi, K.4
Xiao, X.5
Takeda, S.6
Takahashi, K.7
Weiner, H.L.8
Tabira, T.9
-
38
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
Hardy J., Allsop D. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol. Sci. 1991, 12:383-388.
-
(1991)
Trends Pharmacol. Sci.
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
39
-
-
21544468846
-
Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease
-
Hartman R.E., Izumi Y., Bales K.R., Paul S.M., Wozniak D.F., Holtzman D.M. Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease. J. Neurosci. 2005, 25:6213-6220.
-
(2005)
J. Neurosci.
, vol.25
, pp. 6213-6220
-
-
Hartman, R.E.1
Izumi, Y.2
Bales, K.R.3
Paul, S.M.4
Wozniak, D.F.5
Holtzman, D.M.6
-
40
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 1996, 274:99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
41
-
-
4744367412
-
The value of spontaneous alternation behavior (SAB) as a test of retention in pharmacological investigations of memory
-
Hughes R.N. The value of spontaneous alternation behavior (SAB) as a test of retention in pharmacological investigations of memory. Neurosci. Biobehav. Rev. 2004, 28:497-505.
-
(2004)
Neurosci. Biobehav. Rev.
, vol.28
, pp. 497-505
-
-
Hughes, R.N.1
-
42
-
-
0022724941
-
Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease
-
Ihara Y., Nukina N., Miura R., Ogawara M. Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease. J. Biochem. 1986, 99:1807-1810.
-
(1986)
J. Biochem.
, vol.99
, pp. 1807-1810
-
-
Ihara, Y.1
Nukina, N.2
Miura, R.3
Ogawara, M.4
-
43
-
-
2542622162
-
Search strategies used by APP transgenic mice during navigation in the Morris water maze
-
Janus C. Search strategies used by APP transgenic mice during navigation in the Morris water maze. Learn. Mem. 2004, 11:337-346.
-
(2004)
Learn. Mem.
, vol.11
, pp. 337-346
-
-
Janus, C.1
-
45
-
-
0034700471
-
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
Janus C., Pearson J., McLaurin J., Mathews P.M., Jiang Y., Schmidt S.D., Chishti M.A., Horne P., Heslin D., French J., Mount H.T., Nixon R.A., Mercken M., Bergeron C., Fraser P.E., St George-Hyslop P., Westaway D. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 2000, 408:979-982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Horne, P.8
Heslin, D.9
French, J.10
Mount, H.T.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
St George-Hyslop, P.16
Westaway, D.17
-
46
-
-
10044297055
-
Lifelong immunization with human beta-amyloid (1-42) protects Alzheimer's transgenic mice against cognitive impairment throughout aging
-
Jensen M.T., Mottin M.D., Cracchiolo J.R., Leighty R.E., Arendash G.W. Lifelong immunization with human beta-amyloid (1-42) protects Alzheimer's transgenic mice against cognitive impairment throughout aging. Neuroscience 2005, 130:667-684.
-
(2005)
Neuroscience
, vol.130
, pp. 667-684
-
-
Jensen, M.T.1
Mottin, M.D.2
Cracchiolo, J.R.3
Leighty, R.E.4
Arendash, G.W.5
-
47
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R., Head E., Thompson J.L., McIntire T.M., Milton S.C., Cotman C.W., Glabe C.G. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 2003, 300:486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
48
-
-
0036703483
-
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
-
Kotilinek L.A., Bacskai B., Westerman M., Kawarabayashi T., Younkin L., Hyman B.T., Younkin S., Ashe K.H. Reversible memory loss in a mouse transgenic model of Alzheimer's disease. J. Neurosci. 2002, 22:6331-6335.
-
(2002)
J. Neurosci.
, vol.22
, pp. 6331-6335
-
-
Kotilinek, L.A.1
Bacskai, B.2
Westerman, M.3
Kawarabayashi, T.4
Younkin, L.5
Hyman, B.T.6
Younkin, S.7
Ashe, K.H.8
-
49
-
-
0034091707
-
Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation
-
Kumar-Singh S., Dewachter I., Moechars D., Lubke U., De Jonghe C., Ceuterick C., Checler F., Naidu A., Cordell B., Cras P., Van Broeckhoven C., van Leuven F. Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation. Neurobiol. Dis. 2000, 7:9-22.
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 9-22
-
-
Kumar-Singh, S.1
Dewachter, I.2
Moechars, D.3
Lubke, U.4
De Jonghe, C.5
Ceuterick, C.6
Checler, F.7
Naidu, A.8
Cordell, B.9
Cras, P.10
Van Broeckhoven, C.11
van Leuven, F.12
-
50
-
-
13544277841
-
EFRH-phage immunization of Alzheimer's disease animal model improves behavioral performance in Morris water maze trials
-
Lavie V., Becker M., Cohen-Kupiec R., Yacoby I., Koppel R., Wedenig M., Hutter-Paier B., Solomon B. EFRH-phage immunization of Alzheimer's disease animal model improves behavioral performance in Morris water maze trials. J. Mol. Neurosci. 2004, 24:105-113.
-
(2004)
J. Mol. Neurosci.
, vol.24
, pp. 105-113
-
-
Lavie, V.1
Becker, M.2
Cohen-Kupiec, R.3
Yacoby, I.4
Koppel, R.5
Wedenig, M.6
Hutter-Paier, B.7
Solomon, B.8
-
51
-
-
0002173325
-
Cognitive-emotional interactions: listen to the Brain
-
Oxford University Press, New York, Oxford, R.J. Davidson, P. Ekman, K. Scherer (Eds.)
-
LeDoux J.E., Lane R.D., Nadel L. Cognitive-emotional interactions: listen to the Brain. Cognitive Neuroscience of Emotion 2000, 129-155. Oxford University Press, New York, Oxford. R.J. Davidson, P. Ekman, K. Scherer (Eds.).
-
(2000)
Cognitive Neuroscience of Emotion
, pp. 129-155
-
-
LeDoux, J.E.1
Lane, R.D.2
Nadel, L.3
-
52
-
-
33645220400
-
Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice
-
Lee E.B., Leng L.Z., Zhang B., Kwong L., Trojanowski J.Q., Abel T., Lee V.M. Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. J. Biol. Chem. 2006, 281:4292-4299.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 4292-4299
-
-
Lee, E.B.1
Leng, L.Z.2
Zhang, B.3
Kwong, L.4
Trojanowski, J.Q.5
Abel, T.6
Lee, V.M.7
-
53
-
-
0034530636
-
Nasal A beta treatment induces anti-A beta antibody production and decreases cerebral amyloid burden in PD-APP mice
-
Lemere C.A., Maron R., Spooner E.T., Grenfell T.J., Mori C., Desai R., Hancock W.W., Weiner H.L., Selkoe D.J. Nasal A beta treatment induces anti-A beta antibody production and decreases cerebral amyloid burden in PD-APP mice. Ann. N. Y. Acad. Sci. 2000, 920:328-331.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.920
, pp. 328-331
-
-
Lemere, C.A.1
Maron, R.2
Spooner, E.T.3
Grenfell, T.J.4
Mori, C.5
Desai, R.6
Hancock, W.W.7
Weiner, H.L.8
Selkoe, D.J.9
-
54
-
-
0032888131
-
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease
-
Lue L.F., Kuo Y.M., Roher A.E., Brachova L., Shen Y., Sue L., Beach T., Kurth J.H., Rydel R.E., Rogers J. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease. Am. J. Pathol. 1999, 155:853-862.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 853-862
-
-
Lue, L.F.1
Kuo, Y.M.2
Roher, A.E.3
Brachova, L.4
Shen, Y.5
Sue, L.6
Beach, T.7
Kurth, J.H.8
Rydel, R.E.9
Rogers, J.10
-
55
-
-
33646938005
-
Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response
-
Maier M., Seabrook T.J., Lazo N.D., Jiang L., Das P., Janus C., Lemere C.A. Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response. J. Neurosci. 2006, 26:4717-4728.
-
(2006)
J. Neurosci.
, vol.26
, pp. 4717-4728
-
-
Maier, M.1
Seabrook, T.J.2
Lazo, N.D.3
Jiang, L.4
Das, P.5
Janus, C.6
Lemere, C.A.7
-
56
-
-
33847239940
-
Structural principles of tau and the paired helical filaments of Alzheimer's disease
-
Mandelkow E., von Bergen M., Biernat J., Mandelkow E.M. Structural principles of tau and the paired helical filaments of Alzheimer's disease. Brain Pathol. 2007, 17:83-90.
-
(2007)
Brain Pathol.
, vol.17
, pp. 83-90
-
-
Mandelkow, E.1
von Bergen, M.2
Biernat, J.3
Mandelkow, E.M.4
-
57
-
-
0034927082
-
Neurobiology of Pavlovian fear conditioning
-
Maren S. Neurobiology of Pavlovian fear conditioning. Annu. Rev. Neurosci. 2001, 24:897-931.
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 897-931
-
-
Maren, S.1
-
58
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
McLean C.A., Cherny R.A., Fraser F.W., Fuller S.J., Smith M.J., Beyreuther K., Bush A.I., Masters C.L. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann. Neurol. 1999, 46:860-866.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
59
-
-
0033525520
-
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain
-
Moechars D., Dewachter I., Lorent K., Reverse D., Baekelandt V., Naidu A., Tesseur I., Spittaels K., Haute C.V., Checler F., Godaux E., Cordell B., van Leuven F. Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. J. Biol. Chem. 1999, 274:6483-6492.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6483-6492
-
-
Moechars, D.1
Dewachter, I.2
Lorent, K.3
Reverse, D.4
Baekelandt, V.5
Naidu, A.6
Tesseur, I.7
Spittaels, K.8
Haute, C.V.9
Checler, F.10
Godaux, E.11
Cordell, B.12
van Leuven, F.13
-
60
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan D., Diamond D.M., Gottschall P.E., Ugen K.E., Dickey C., Hardy J., Duff K., Jantzen P., DiCarlo G., Wilcock D., Connor K., Hatcher J., Hope C., Gordon M., Arendash G.W. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 2000, 408:982-985.
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
Duff, K.7
Jantzen, P.8
DiCarlo, G.9
Wilcock, D.10
Connor, K.11
Hatcher, J.12
Hope, C.13
Gordon, M.14
Arendash, G.W.15
-
61
-
-
0021173996
-
Developments of a water-maze procedure for studying spatial learning in the rat
-
Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J. Neurosci. Methods 1984, 11:47-60.
-
(1984)
J. Neurosci. Methods
, vol.11
, pp. 47-60
-
-
Morris, R.1
-
62
-
-
34347399599
-
Oral vaccination with a viral vector containing Abeta cDNA attenuates age-related Abeta accumulation and memory deficits without causing inflammation in a mouse Alzheimer model
-
Mouri A., Noda Y., Hara H., Mizoguchi H., Tabira T., Nabeshima T. Oral vaccination with a viral vector containing Abeta cDNA attenuates age-related Abeta accumulation and memory deficits without causing inflammation in a mouse Alzheimer model. FASEB J. 2007, 21:2135-2148.
-
(2007)
FASEB J.
, vol.21
, pp. 2135-2148
-
-
Mouri, A.1
Noda, Y.2
Hara, H.3
Mizoguchi, H.4
Tabira, T.5
Nabeshima, T.6
-
63
-
-
47749107621
-
Reducing AD-like pathology in 3×Tg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy
-
Movsesyan N., Ghochikyan A., Mkrtichyan M., Petrushina I., Davtyan H., Olkhanud P.B., Head E., Biragyn A., Cribbs D.H., Agadjanyan M.G. Reducing AD-like pathology in 3×Tg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy. PLoS ONE 2008, 3:e2124.
-
(2008)
PLoS ONE
, vol.3
-
-
Movsesyan, N.1
Ghochikyan, A.2
Mkrtichyan, M.3
Petrushina, I.4
Davtyan, H.5
Olkhanud, P.B.6
Head, E.7
Biragyn, A.8
Cribbs, D.H.9
Agadjanyan, M.G.10
-
64
-
-
0034213718
-
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation
-
Mucke L., Masliah E., Yu G.Q., Mallory M., Rockenstein E.M., Tatsuno G., Hu K., Kholodenko D., Johnson-Wood K., McConlogue L. High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci. 2000, 20:4050-4058.
-
(2000)
J. Neurosci.
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.Q.3
Mallory, M.4
Rockenstein, E.M.5
Tatsuno, G.6
Hu, K.7
Kholodenko, D.8
Johnson-Wood, K.9
McConlogue, L.10
-
65
-
-
34547473731
-
Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice
-
Muhs A., Hickman D.T., Pihlgren M., Chuard N., Giriens V., Meerschman C., van d.A.I., van Leuven F., Sugawara M., Weingertner M.C., Bechinger B., Greferath R., Kolonko N., Nagel-Steger L., Riesner D., Brady R.O., Pfeifer A., Nicolau C. Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:9810-9815.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 9810-9815
-
-
Muhs, A.1
Hickman, D.T.2
Pihlgren, M.3
Chuard, N.4
Giriens, V.5
Meerschman, C.6
van, D.7
van Leuven, F.8
Sugawara, M.9
Weingertner, M.C.10
Bechinger, B.11
Greferath, R.12
Kolonko, N.13
Nagel-Steger, L.14
Riesner, D.15
Brady, R.O.16
Pfeifer, A.17
Nicolau, C.18
-
66
-
-
51749097108
-
Immunotherapy and naturally occurring autoantibodies in neurodegenerative disorders
-
Neff F., Wei X., Nolker C., Bacher M., Du Y., Dodel R. Immunotherapy and naturally occurring autoantibodies in neurodegenerative disorders. Autoimmun. Rev. 2008, 7:501-507.
-
(2008)
Autoimmun. Rev.
, vol.7
, pp. 501-507
-
-
Neff, F.1
Wei, X.2
Nolker, C.3
Bacher, M.4
Du, Y.5
Dodel, R.6
-
67
-
-
0034672421
-
Alzheimer's disease: a dysfunction of the amyloid precursor protein(1)
-
Neve R.L., McPhie D.L., Chen Y. Alzheimer's disease: a dysfunction of the amyloid precursor protein(1). Brain Res. 2000, 886:54-66.
-
(2000)
Brain Res.
, vol.886
, pp. 54-66
-
-
Neve, R.L.1
McPhie, D.L.2
Chen, Y.3
-
68
-
-
33847049400
-
Alzheimer disease: amyloidogenesis, the presenilins and animal models
-
Newman M., Musgrave I.F., Lardelli M. Alzheimer disease: amyloidogenesis, the presenilins and animal models. Biochim. Biophys. Acta 2007, 1772:285-297.
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, pp. 285-297
-
-
Newman, M.1
Musgrave, I.F.2
Lardelli, M.3
-
69
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report
-
Nicoll J.A., Wilkinson D., Holmes C., Steart P., Markham H., Weller R.O. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat. Med. 2003, 9:448-452.
-
(2003)
Nat. Med.
, vol.9
, pp. 448-452
-
-
Nicoll, J.A.1
Wilkinson, D.2
Holmes, C.3
Steart, P.4
Markham, H.5
Weller, R.O.6
-
70
-
-
33846015514
-
Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles
-
Oddo S., Vasilevko V., Caccamo A., Kitazawa M., Cribbs D.H., LaFerla F.M. Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles. J. Biol. Chem. 2006, 281:39413-39423.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 39413-39423
-
-
Oddo, S.1
Vasilevko, V.2
Caccamo, A.3
Kitazawa, M.4
Cribbs, D.H.5
LaFerla, F.M.6
-
71
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction
-
Oddo S., Caccamo A., Shepherd J.D., Murphy M.P., Golde T.E., Kayed R., Metherate R., Mattson M.P., Akbari Y., LaFerla F.M. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 2003, 39:409-421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
72
-
-
0031871740
-
Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy
-
Pitschke M., Prior R., Haupt M., Riesner D. Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy. Nat. Med. 1998, 4:832-834.
-
(1998)
Nat. Med.
, vol.4
, pp. 832-834
-
-
Pitschke, M.1
Prior, R.2
Haupt, M.3
Riesner, D.4
-
73
-
-
33748988258
-
Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
-
Radde R., Bolmont T., Kaeser S.A., Coomaraswamy J., Lindau D., Stoltze L., Calhoun M.E., Jaggi F., Wolburg H., Gengler S., Haass C., Ghetti B., Czech C., Holscher C., Mathews P.M., Jucker M. Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. EMBO Rep. 2006, 7:940-946.
-
(2006)
EMBO Rep.
, vol.7
, pp. 940-946
-
-
Radde, R.1
Bolmont, T.2
Kaeser, S.A.3
Coomaraswamy, J.4
Lindau, D.5
Stoltze, L.6
Calhoun, M.E.7
Jaggi, F.8
Wolburg, H.9
Gengler, S.10
Haass, C.11
Ghetti, B.12
Czech, C.13
Holscher, C.14
Mathews, P.M.15
Jucker, M.16
-
74
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D., Barbour R., Dunn W., Gordon G., Grajeda H., Guido T., Hu K., Huang J., Johnson-Wood K., Khan K., Kholodenko D., Lee M., Liao Z., Lieberburg I., Motter R., Mutter L., Soriano F., Shopp G., Vasquez N., Vandevert C., Walker S., Wogulis M., Yednock T., Games D., Seubert P. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 1999, 400:173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
75
-
-
0035066332
-
Alzheimer's disease: genes, proteins, and therapy
-
Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 2001, 81:741-766.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
76
-
-
44549087765
-
Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior
-
Selkoe D.J. Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior. Behav. Brain Res. 2008, 192(1):106-113.
-
(2008)
Behav. Brain Res.
, vol.192
, Issue.1
, pp. 106-113
-
-
Selkoe, D.J.1
-
77
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar G.M., Li S., Mehta T.H., Garcia-Munoz A., Shepardson N.E., Smith I., Brett F.M., Farrell M.A., Rowan M.J., Lemere C.A., Regan C.M., Walsh D.M., Sabatini B.L., Selkoe D.J. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat. Med. 2008, 14(8):837-842.
-
(2008)
Nat. Med.
, vol.14
, Issue.8
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
Walsh, D.M.12
Sabatini, B.L.13
Selkoe, D.J.14
-
78
-
-
0034884382
-
Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice
-
Sigurdsson E.M., Scholtzova H., Mehta P.D., Frangione B., Wisniewski T. Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. Am. J. Pathol. 2001, 159:439-447.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 439-447
-
-
Sigurdsson, E.M.1
Scholtzova, H.2
Mehta, P.D.3
Frangione, B.4
Wisniewski, T.5
-
79
-
-
3242694207
-
An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives
-
Sigurdsson E.M., Knudsen E., Asuni A., Fitzer-Attas C., Sage D., Quartermain D., Goni F., Frangione B., Wisniewski T. An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives. J. Neurosci. 2004, 24:6277-6282.
-
(2004)
J. Neurosci.
, vol.24
, pp. 6277-6282
-
-
Sigurdsson, E.M.1
Knudsen, E.2
Asuni, A.3
Fitzer-Attas, C.4
Sage, D.5
Quartermain, D.6
Goni, F.7
Frangione, B.8
Wisniewski, T.9
-
80
-
-
33947596205
-
Active immunization against Alzheimer's beta-amyloid peptide using phage display technology
-
Solomon B. Active immunization against Alzheimer's beta-amyloid peptide using phage display technology. Vaccine 2007, 25:3053-3056.
-
(2007)
Vaccine
, vol.25
, pp. 3053-3056
-
-
Solomon, B.1
-
81
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C., Abramowski D., Duke M., Wiederhold K.H., Mistl C., Rothacher S., Ledermann B., Burki K., Frey P., Paganetti P.A., Waridel C., Calhoun M.E., Jucker M., Probst A., Staufenbiel M., Sommer B. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:13287-13292.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Burki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
82
-
-
33750503415
-
Drug discovery in dementia: the role of rodent models
-
Van Dam D., De Deyn P.P. Drug discovery in dementia: the role of rodent models. Nat. Rev. Drug Discov. 2006, 5:956-970.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 956-970
-
-
Van Dam, D.1
De Deyn, P.P.2
-
83
-
-
32644474211
-
Effect of Morris water maze diameter on visual-spatial learning in different mouse strains
-
Van Dam D., Lenders G., De Deyn P.P. Effect of Morris water maze diameter on visual-spatial learning in different mouse strains. Neurobiol. Learn. Mem. 2006, 85:164-172.
-
(2006)
Neurobiol. Learn. Mem.
, vol.85
, pp. 164-172
-
-
Van Dam, D.1
Lenders, G.2
De Deyn, P.P.3
-
84
-
-
5344277556
-
Deciphering the molecular basis of memory failure in Alzheimer's disease
-
Walsh D.M., Selkoe D.J. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 2004, 44:181-193.
-
(2004)
Neuron
, vol.44
, pp. 181-193
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
85
-
-
14244255355
-
Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage
-
Wilcock D.M., Rojiani A., Rosenthal A., Subbarao S., Freeman M.J., Gordon M.N., Morgan D. Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage. J. Neuroinflammation 2004, 1:24.
-
(2004)
J. Neuroinflammation
, vol.1
, pp. 24
-
-
Wilcock, D.M.1
Rojiani, A.2
Rosenthal, A.3
Subbarao, S.4
Freeman, M.J.5
Gordon, M.N.6
Morgan, D.7
-
86
-
-
33745001453
-
Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice
-
Wilcock D.M., Alamed J., Gottschall P.E., Grimm J., Rosenthal A., Pons J., Ronan V., Symmonds K., Gordon M.N., Morgan D. Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice. J. Neurosci. 2006, 26:5340-5346.
-
(2006)
J. Neurosci.
, vol.26
, pp. 5340-5346
-
-
Wilcock, D.M.1
Alamed, J.2
Gottschall, P.E.3
Grimm, J.4
Rosenthal, A.5
Pons, J.6
Ronan, V.7
Symmonds, K.8
Gordon, M.N.9
Morgan, D.10
-
87
-
-
10744225891
-
A novel recombinant adeno-associated virus vaccine reduces behavioral impairment and beta-amyloid plaques in a mouse model of Alzheimer's disease
-
Zhang J., Wu X., Qin C., Qi J., Ma S., Zhang H., Kong Q., Chen D., Ba D., He W. A novel recombinant adeno-associated virus vaccine reduces behavioral impairment and beta-amyloid plaques in a mouse model of Alzheimer's disease. Neurobiol. Dis. 2003, 14:365-379.
-
(2003)
Neurobiol. Dis.
, vol.14
, pp. 365-379
-
-
Zhang, J.1
Wu, X.2
Qin, C.3
Qi, J.4
Ma, S.5
Zhang, H.6
Kong, Q.7
Chen, D.8
Ba, D.9
He, W.10
-
88
-
-
48349117119
-
Vaccination of Alzheimer's model mice with adenovirus vector containing quadrivalent foldable Abeta(1-15) reduces Abeta burden and behavioral impairment without Abeta-specific T cell response
-
Zou J., Yao Z., Zhang G., Wang H., Xu J., Yew D.T., Forster E.L. Vaccination of Alzheimer's model mice with adenovirus vector containing quadrivalent foldable Abeta(1-15) reduces Abeta burden and behavioral impairment without Abeta-specific T cell response. J. Neurol. Sci. 2008, 272:87-98.
-
(2008)
J. Neurol. Sci.
, vol.272
, pp. 87-98
-
-
Zou, J.1
Yao, Z.2
Zhang, G.3
Wang, H.4
Xu, J.5
Yew, D.T.6
Forster, E.L.7
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