Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-β and interleukin-4

Molecular Therapy

Volumn 16, Issue 5, 2008, Pages 845-853

  Frazer, Maria E ^a   Hughes, Jennifer E ^a   Mastrangelo, Michael A ^a   Tibbens, Jennifer L ^a   Federoff, Howard J ^a   Bowers, William J ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; INTERLEUKIN 4; TAU PROTEIN; VIRUS VECTOR;

ALZHEIMER DISEASE; AMPLICON; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DISEASE MODEL; DRUG EFFICACY; DRUG SAFETY; GENE EXPRESSION; HERPES SIMPLEX VIRUS; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOTHERAPY; LEARNING; MAZE TEST; MEMORY CONSOLIDATION; MOUSE; NEUROFIBRILLARY TANGLE; NONHUMAN; OUTCOME ASSESSMENT; SENILE PLAQUE; SPATIAL MEMORY; TASK PERFORMANCE; TH2 CELL; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM;

MUS; SIMPLEXVIRUS;

EID: 42549089024     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2008.39     Document Type: Article

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