-
1
-
-
33645728523
-
Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications
-
Skovronsky D.M., Lee V.M., and Trojanowski J.Q. Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications. Annu Rev Pathol 1 (2006) 151-170
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 151-170
-
-
Skovronsky, D.M.1
Lee, V.M.2
Trojanowski, J.Q.3
-
2
-
-
47949132196
-
Active and passive immunotherapy for neurodegenerative disorders
-
Brody D.L., and Holtzman D.M. Active and passive immunotherapy for neurodegenerative disorders. Annu Rev Neurosci 31 (2008) 175-193
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 175-193
-
-
Brody, D.L.1
Holtzman, D.M.2
-
3
-
-
34247402084
-
Autoantibodies to alpha-synuclein in inherited Parkinson's disease
-
Papachroni K.K., Ninkina N., Papapanagiotou A., et al. Autoantibodies to alpha-synuclein in inherited Parkinson's disease. J Neurochem 101 (2007) 749-756
-
(2007)
J Neurochem
, vol.101
, pp. 749-756
-
-
Papachroni, K.K.1
Ninkina, N.2
Papapanagiotou, A.3
-
4
-
-
0036085702
-
Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals
-
Weksler M.E., Relkin N., Turkenich R., LaRusse S., Zhou L., and Szabo P. Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals. Exp Gerontol 37 (2002) 943-948
-
(2002)
Exp Gerontol
, vol.37
, pp. 943-948
-
-
Weksler, M.E.1
Relkin, N.2
Turkenich, R.3
LaRusse, S.4
Zhou, L.5
Szabo, P.6
-
5
-
-
0035845614
-
Reduced levels of amyloid ß-peptide antibody in Alzheimer's disease
-
Du Y., Dodel R., Hampel H., et al. Reduced levels of amyloid ß-peptide antibody in Alzheimer's disease. Neurology 57 (2001) 801-805
-
(2001)
Neurology
, vol.57
, pp. 801-805
-
-
Du, Y.1
Dodel, R.2
Hampel, H.3
-
6
-
-
51749088624
-
Human anti-prion protein antibodies block A117V PrP peptide fibril formation and prevent A117V PrP peptide-induced neurotoxicity
-
Program number: 12.17.2007
-
Wei X., Wei G., Farlow M., and Du Y. Human anti-prion protein antibodies block A117V PrP peptide fibril formation and prevent A117V PrP peptide-induced neurotoxicity. Abstr Soc Neurosci 33 (2007) Program number: 12.17.2007
-
(2007)
Abstr Soc Neurosci
, vol.33
-
-
Wei, X.1
Wei, G.2
Farlow, M.3
Du, Y.4
-
7
-
-
0003729067
-
Natural autoimmunity
-
Shoenfeld Y., and Isenberg D.A. (Eds), Elsevier, Amsterdam
-
Shoenfeld Y., and Isenberg D.A. Natural autoimmunity. In: Shoenfeld Y., and Isenberg D.A. (Eds). The mosaic of autoimmunity (1989), Elsevier, Amsterdam 53-74
-
(1989)
The mosaic of autoimmunity
, pp. 53-74
-
-
Shoenfeld, Y.1
Isenberg, D.A.2
-
8
-
-
33645829653
-
Has the amyloid cascade hypothesis for AD been proved?
-
Hardy J. Has the amyloid cascade hypothesis for AD been proved?. Curr Alzheimer Res 3 (2006) 71-73
-
(2006)
Curr Alzheimer Res
, vol.3
, pp. 71-73
-
-
Hardy, J.1
-
9
-
-
0036780877
-
Amyloid-beta immunotherapy for AD: the end of the beginning
-
Schenk D. Amyloid-beta immunotherapy for AD: the end of the beginning. Nat Rev Neurosci 3 (2002) 824-828
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 824-828
-
-
Schenk, D.1
-
10
-
-
0041320819
-
Human anti-beta-amyloid antibodies block beta-amyloid fibril formation and prevent beta-amyloid-induced neurotoxicity
-
Du Y., Wei X., Dodel R., et al. Human anti-beta-amyloid antibodies block beta-amyloid fibril formation and prevent beta-amyloid-induced neurotoxicity. Brain 126 (2003) 1935-1939
-
(2003)
Brain
, vol.126
, pp. 1935-1939
-
-
Du, Y.1
Wei, X.2
Dodel, R.3
-
11
-
-
4644275963
-
Intravenous immunoglobulins containing antibodies against ß-amyloid for the treatment of Alzheimer's disease
-
Dodel R., Du Y., Depboylu C., et al. Intravenous immunoglobulins containing antibodies against ß-amyloid for the treatment of Alzheimer's disease. J Neurol Neurosurg Psychiatry 75 (2004) 1472-1474
-
(2004)
J Neurol Neurosurg Psychiatry
, vol.75
, pp. 1472-1474
-
-
Dodel, R.1
Du, Y.2
Depboylu, C.3
-
12
-
-
34247506244
-
Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system
-
Bell R.D., Sagare A.P., Friedman A.E., et al. Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system. J Cereb Blood Flow Metab 27 (2007) 909-918
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 909-918
-
-
Bell, R.D.1
Sagare, A.P.2
Friedman, A.E.3
-
13
-
-
0035902619
-
Peripheral anti-Ab antibody alters CNS and plasma Aß clearance and decreases brain Ab burden in a mouse model of AD
-
DeMattos R.B., Bales K.R., Cummins D.J., Dodart J.C., Paul S.M., and Holtzman D.M. Peripheral anti-Ab antibody alters CNS and plasma Aß clearance and decreases brain Ab burden in a mouse model of AD. Proc Natl Acad Sci U S A 98 (2001) 8850-8855
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 8850-8855
-
-
DeMattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Dodart, J.C.4
Paul, S.M.5
Holtzman, D.M.6
-
14
-
-
51749121284
-
-
N.R. Relkin P. Szabo B. Adamiak 18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease. Neurobiol. Aging in press.
-
N.R. Relkin P. Szabo B. Adamiak 18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease. Neurobiol. Aging in press.
-
-
-
-
15
-
-
34548318990
-
Physiological and pathological properties of alpha-synuclein
-
Tofaris G.K., and Spillantini M.G. Physiological and pathological properties of alpha-synuclein. Cell Mol Life Sci 64 (2007) 2194-2201
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 2194-2201
-
-
Tofaris, G.K.1
Spillantini, M.G.2
-
16
-
-
0033565874
-
Alpha-synuclein shares physical and functional homology with 14-3-3 proteins
-
Ostrerova N., Petrucelli L., Farrer M., et al. Alpha-synuclein shares physical and functional homology with 14-3-3 proteins. J Neurosci 19 (1999) 5782-5791
-
(1999)
J Neurosci
, vol.19
, pp. 5782-5791
-
-
Ostrerova, N.1
Petrucelli, L.2
Farrer, M.3
-
17
-
-
0029127954
-
Characterization of a novel protein regulated during the critical period for song learning in the zebra finch
-
George J.M., Jin H., Woods W.S., and Clayton D.F. Characterization of a novel protein regulated during the critical period for song learning in the zebra finch. Neuron 15 (1995) 361-372
-
(1995)
Neuron
, vol.15
, pp. 361-372
-
-
George, J.M.1
Jin, H.2
Woods, W.S.3
Clayton, D.F.4
-
18
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich A., Schmitz Y., Farinas I., et al. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron 25 (2000) 239-252
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
-
19
-
-
0036777847
-
Synergistic effects of pesticides and metals on the fibrillation of alpha-synuclein: implications for Parkinson's disease
-
Uversky V.N., Li J., Bower K., and Fink A.L. Synergistic effects of pesticides and metals on the fibrillation of alpha-synuclein: implications for Parkinson's disease. Neurotoxicology 23 (2002) 527-536
-
(2002)
Neurotoxicology
, vol.23
, pp. 527-536
-
-
Uversky, V.N.1
Li, J.2
Bower, K.3
Fink, A.L.4
-
20
-
-
0036174010
-
Alpha-synuclein is phosphorylated in synucleinopathy lesions
-
Fujiwara H., Hasegawa M., Dohmae N., et al. Alpha-synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Boil 4 (2002) 160-164
-
(2002)
Nat Cell Boil
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
-
21
-
-
9144229591
-
Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation
-
Hodara R., Norris E.H., Giasson B.I., et al. Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. J Biol Chem 279 (2004) 47746-47753
-
(2004)
J Biol Chem
, vol.279
, pp. 47746-47753
-
-
Hodara, R.1
Norris, E.H.2
Giasson, B.I.3
-
22
-
-
0038386274
-
Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease
-
Volles M.J., and Lansbury Jr. P.T. Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease. Biochemistry 42 (2003) 7871-7878
-
(2003)
Biochemistry
, vol.42
, pp. 7871-7878
-
-
Volles, M.J.1
Lansbury Jr., P.T.2
-
23
-
-
33645833848
-
Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease
-
El-Agnaf O.M., Salem S.A., Paleologou K.E., et al. Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease. Faseb J 20 (2006) 419-425
-
(2006)
Faseb J
, vol.20
, pp. 419-425
-
-
El-Agnaf, O.M.1
Salem, S.A.2
Paleologou, K.E.3
-
24
-
-
19944429065
-
Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease
-
Masliah E., Hansen L., Adame A., et al. Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease. Neurology 64 (2005) 129-131
-
(2005)
Neurology
, vol.64
, pp. 129-131
-
-
Masliah, E.1
Hansen, L.2
Adame, A.3
-
25
-
-
34147130637
-
Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicity
-
Emadi S., Barkhordarian H., Wang M.S., Schulz P., and Sierks M.R. Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicity. Biol 368 (2007) 1132-1144
-
(2007)
Biol
, vol.368
, pp. 1132-1144
-
-
Emadi, S.1
Barkhordarian, H.2
Wang, M.S.3
Schulz, P.4
Sierks, M.R.5
-
26
-
-
3042592589
-
Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease
-
Benner E.J., Mosley R.L., Destache C.J., et al. Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A 101 (2004) 9435-9440
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9435-9440
-
-
Benner, E.J.1
Mosley, R.L.2
Destache, C.J.3
-
27
-
-
33748857338
-
Pathogenesis of prion diseases: current status and future outlook
-
Aguzzi A., and Heikenwalder M. Pathogenesis of prion diseases: current status and future outlook. Nat Rev Microbiol 4 (2006) 765-775
-
(2006)
Nat Rev Microbiol
, vol.4
, pp. 765-775
-
-
Aguzzi, A.1
Heikenwalder, M.2
-
28
-
-
34547475050
-
Prion proteins: a biological role beyond prion diseases
-
Hu W., Rosenberg R.N., and Stuve O. Prion proteins: a biological role beyond prion diseases. Acta Neurol Scand 116 (2007) 75-82
-
(2007)
Acta Neurol Scand
, vol.116
, pp. 75-82
-
-
Hu, W.1
Rosenberg, R.N.2
Stuve, O.3
-
29
-
-
33645750334
-
Emerging pharmacotherapies for Creutzfeldt-Jakob disease
-
Korth C., and Peters P.J. Emerging pharmacotherapies for Creutzfeldt-Jakob disease. Arch Neurol 63 (2006) 497-501
-
(2006)
Arch Neurol
, vol.63
, pp. 497-501
-
-
Korth, C.1
Peters, P.J.2
-
30
-
-
0035979274
-
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
-
Enari M., Flechsig E., and Weissmann C. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc Natl Acad Sci U S A 98 (2001) 9295-9299
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9295-9299
-
-
Enari, M.1
Flechsig, E.2
Weissmann, C.3
-
31
-
-
0035899413
-
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
-
Peretz D., Williamson R.A., Kaneko K., et al. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature 412 (2001) 739-743
-
(2001)
Nature
, vol.412
, pp. 739-743
-
-
Peretz, D.1
Williamson, R.A.2
Kaneko, K.3
-
32
-
-
0037422133
-
Monoclonal antibodies inhibit prion replication and delay the development of prion disease
-
White A.R., Enever P., Tayebi M., et al. Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature 422 (2003) 80-83
-
(2003)
Nature
, vol.422
, pp. 80-83
-
-
White, A.R.1
Enever, P.2
Tayebi, M.3
-
33
-
-
34447629569
-
Therapeutic approaches for prion and AD
-
Wisniewski T., and Sigurdsson E.M. Therapeutic approaches for prion and AD. FEBS J 274 (2007) 3784-3798
-
(2007)
FEBS J
, vol.274
, pp. 3784-3798
-
-
Wisniewski, T.1
Sigurdsson, E.M.2
-
34
-
-
0035812752
-
Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies
-
Heppner F.L., Musahl C., Arrighi I., et al. Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science 294 (2001) 178-182
-
(2001)
Science
, vol.294
, pp. 178-182
-
-
Heppner, F.L.1
Musahl, C.2
Arrighi, I.3
-
35
-
-
33947194272
-
Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells
-
Handisurya A., Gilch S., Winter D., et al. Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells. Febs J 274 (2007) 1747-1758
-
(2007)
Febs J
, vol.274
, pp. 1747-1758
-
-
Handisurya, A.1
Gilch, S.2
Winter, D.3
-
36
-
-
0141782730
-
Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent
-
Schwarz A., Kratke O., Burwinkel M., et al. Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent. Neurosci Lett 350 (2003) 187-189
-
(2003)
Neurosci Lett
, vol.350
, pp. 187-189
-
-
Schwarz, A.1
Kratke, O.2
Burwinkel, M.3
-
37
-
-
34247234606
-
Potential of active and passive immunizations for the prevention and therapy of transmissible spongiform encephalopathies
-
Bade S., and Frey A. Potential of active and passive immunizations for the prevention and therapy of transmissible spongiform encephalopathies. Expert Rev Vaccines 6 (2007) 153-168
-
(2007)
Expert Rev Vaccines
, vol.6
, pp. 153-168
-
-
Bade, S.1
Frey, A.2
-
38
-
-
33846462056
-
Prions and prion diseases
-
Beekes M. Prions and prion diseases. FEBS J 274 (2007) 575
-
(2007)
FEBS J
, vol.274
, pp. 575
-
-
Beekes, M.1
-
39
-
-
15744395826
-
Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations
-
Fioriti L., Dossena S., Stewart L.R., et al. Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations. J Biol Chem 280 (2005) 11320-11328
-
(2005)
J Biol Chem
, vol.280
, pp. 11320-11328
-
-
Fioriti, L.1
Dossena, S.2
Stewart, L.R.3
-
40
-
-
0032212367
-
Prion protein-overexpressing cells show altered response to a neurotoxic prion protein peptide
-
Brown D.R. Prion protein-overexpressing cells show altered response to a neurotoxic prion protein peptide. J Neurosci Res 54 (1998) 331-340
-
(1998)
J Neurosci Res
, vol.54
, pp. 331-340
-
-
Brown, D.R.1
|