Neuropathological diagnosis of Alzheimer's disease: A perspective from longitudinal clinicopathological studies

Neurobiology of Aging

Volumn 18, Issue 4 SUPPL., 1997, Pages

  Dickson, D W ^a  

^a Albert E   (United States)

Author keywords

Amyloid; Dystrophic neurites; Neurofibrillary tangles; Paired helical filaments; Prospective clinicopathological studies; Senile plaques

Indexed keywords

AGING; ALZHEIMER DISEASE; CLINICAL EXAMINATION; COGNITIVE DEFECT; HISTOPATHOLOGY; HUMAN; NEOCORTEX; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; PRIORITY JOURNAL; REVIEW; SENILE PLAQUE;

EID: 0030660554     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(97)00065-1     Document Type: Article

References (40)

1. Arai H., Lee V. M., Otvos L. Jr, Greenberg B. D., Lowery D. E., Sharma S. K., Schmidt M. L., Trojanowski J. Q. Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques. Proc. Natl. Acad. Sci. USA. 87:1990;2249-2253.
2. Arriagada P. V., Marzloff K., Hyman B. T. Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease. Neurology. 9:1992;1681-1688.
3. Bancher C., Braak H., Fischer P., Jellinger K. A. Neuropathological staging of Alzheimer lesions and intellectual status in Alzheimer's and Parkinson's disease patients. Neurosci. Lett. 162:1993;179-182.
4. Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 82:1991;239-259.
5. Crystal H. A., Dickson D. W., Sliwinski M., Lipton R., Grober E., Marks-Nelson H., Antis P. Pathological markers associated with normal aging and dementia in the elderly. Ann. Neurol. 34:1993;566-573.
6. Crystal H. A., Dickson D. W., Sliwinski M., Lipton R. B., Blau A., Masur D. Associations of status and change measures of neuropsychological function with pathology in elderly, originally nondemented subjects. Arch. Neurol. 53:1996;82-87.
7. Davies L., Molska B., Hilbich C., Multhaup G., Martins R., Simms G., Beyreuther K., Masters C. L. A4 amyloid deposition and the diagnosis of Alzheimer's disease Prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques . Neurology. 38:1988;1688-1693.
8. Delaere P., He Y., Fayet G., Duyckaerts C., Hauw J. J. Beta A4 deposits are constant in the brain of the oldest old an immunocytochemical study of 20 French centenarians . Neurobiol. Aging. 14:1993;191-194.
9. Dickson, D. W. Aging in the central nervous system. In: Markesbery, W., ed. Neuropathology of Dementing Disorders, Edward Arnold Publishers, London, 1997 (in press).
10. Dickson D. W., Yen S. -H. Beta-amyloid deposition and paired helical filament formation Which histopathological feature is more significant in Alzheimer's disease? Neurobiol. Aging. 10:1989;402-404.
11. Dickson D. W., Crystal H., Mattiace L. A., Kress Y., Schwagerl A., Ksiezak-Reding H., Davies P., Yen S. -H. Diffuse Lewy body disease Light and electron microscopic immunocytochemistry of senile plaques . Acta Neuropathol. (Berlin). 78:1989;572-584.
12. Dickson D. W., Crystal H. A., Bevona C., Honer W., Vincent I., Davies P. Correlations of synaptic markers with cognitive status in prospectively studied elderly humans. Neurobiol. Aging. 16:1995;285-298.
13. Dickson D. W., Crystal H. A., Mattiace L. A., Masur D. M., Blau A. D., Davies P., Yen S. -H., Aronoson M. K. Identification of normal and pathological aging in prospectively studied nondemented elderly humans. Neurobiol. Aging. 13:1991;179-189.
14. Dickson D. W., Farlo J., Davies P., Crystal H., Fuld P., Yen S. -H. Alzheimer's disease A double-labeling immunohistochemical study of senile plaques . Am. J. Pathol. 132:1988;86-101.
15. Dickson D. W., Ivanushkin A., Heitner J., Yen S. -H., Davies P. Apolipoprotein-E immunoreactivity is increased in deposits of Alzheimer's disease, but not pathological aging or diffuse Lewy body disease. Iqbal H., Mortimer J. A., Winblad B., Wisniewski H. M. Research advances in Alzheimer's disease and related disorders. 1995;371-383 John Wiley & Sons, New York.
16. Dickson D. W., Sinicropi S., Yen S. -H., Ko L. -W., Mattiace L. A., Bucala R., Vlassara H. Glycation and microglial reaction in lesions of Alzheimer's disease. Neurobiol. Aging. 17:1996;733-743.
17. Dickson D. W., Wertkin A., Kress Y., Ksiezak-Reding H., Yen S. -H. Ubiquitin immunoreactive structures in normal brains Distribution and developmental aspects . Lab. Invest. 63:1990;87-99.
18. Gibson P. H. Form and distribution of senile plaques seen in silver impregnated sections in the brains of intellectually normal elderly people and people with Alzheimer-type dementia. Neuropathol. Appl. Neurobiol. 9:1983;379-389.
19. Goedert M., Jakes R., Spillantini M. G., Hasegawa M., Smith M. J., Crowther R. A. Assembly of microtubule-associated tau into Alzheimer-like filaments induced by sulfated glycosaminoglycans. Nature. 383:1996;550-553.
20. Gowing E., Roher A. E., Woods A. S., Cotter R. J., Chaney M., Little S. P., Ball M. J. Chemical characterization of the Aβ17-42 peptide, a component of diffuse amyloid deposits of Alzheimer's disease. J. Biol. Chem. 269:1994;10987-10990.
21. Grundke-Iqbal I., Iqbal K., Tung Y. C., Quinlan M., Wisniewski H. M., Binder L. I. Abnormal phosphorylation of the microtubule-associated protein tau (τ) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. USA. 83:1986;4913-4917.
22. Haas C., Schlossmacher M. G., Hung A. Y., Vigo-Pelfrey C., Mellon A., Ostaszewski B. L., Lieberburg I., Koo E. H., Schenk D., Teplow D. B., Selkoe D. J. Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature. 359:1992;322-325.
23. Hansen L. A., Masliah E., Galasko D., Terry R. D. Plaque-only Alzheimer disease is usually Lewy body variant, and vise versa. J. Neuropathol. Exp. Neurol. 52:1994;648-654.
24. He Y., Delaère P., Duyckaerts C., Wasowicz M., Piette F., Hauw J. -J. Two distinct ubiquitin immunoreactive senile plaques in Alzheimer's disease Relationship with the intellectual status in 29 cases . Acta Neuropathol. 86:1993;109-116.
25. Iwatsubo T., Odaka A., Suzuki N., Mizusawa H., Nukina N., Ihara Y. Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals Evidence that an initially deposited species is Aβ42(43) . Neuron. 13:1994;45-53.
26. Khachaturian Z. S. Diagnosis of Alzheimer's disease. Arch. Neurol. 42:1985;1097-1105.
27. Lee V. M., Balin B. J., Otvos L. Jr, Trojanowski J. Q. A68 A major subunit of paired helical filaments and derivatized forms of normal tau . Science. 251:1991;675-678.
28. Liu W. -K., Williams R. T., Hall F. L., Dickson D. W., Yen S. -H. Detection of a cdc2-related kinase associated with Alzheimer paired helical filaments. Am. J. Pathol. 146:1995;228-238.
29. Masliah E., Sisk A., Mallory M., Mucke L., Schenk D., Games D. Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β amyloid precursor protein and Alzheimer's disease. J. Neurosci. 16:1996;5795-5811.
30. McKeith I. G., Galasko D., Kosaka K., Perry E. K., Dickson D. W., Hansen L. A., Salmon D. P., Lowe J., Mirra S. S., Byrne E. J., Quinn N. P., Edwardson J. A., Ince P. A., Bergeron C., Burns A., Miller B. L., Lovestone S., Collerton D., Jansen E. N. H., de Vos R. A. I., Wilcock G. K., Jellinger K. A., Perry R. H. Consensus guidelines for the clinical and pathological diagnosis of dementia with Lewy bodies (DLB) Report of the consortium on DLB international workshop . Neurology. 47:1996;1113-1124.
31. Price J. L., Davis P. B., Morris J. C., White D. L. The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease. Neurobiol. Aging. 12:1991;295-312.
32. Probst A., Anderton B. H., Brion J. -P., Ulrich J. Senile plaque neurites fail to demonstrate anti-paired helical filament and anti-microtubule-associated protein-tau immunoreactive proteins in the absence of neurofibrillary tangles in the neocortex. Acta Neuropathol. 77:1989;430-436.
33. Roher A. E., Lowenson J. D., Clarke S., Wolkow C., Wang R., Cotter R. J., Reardon I. M., Zurcher-Neely H. A., Heinriksonm R. L., Ball M. J., Greenberg B. D. Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease. J. Biol. Chem. 268:1993;3072-3083.
34. Selkoe D. J. Alzheimer's disease a central role for amyloid . J. Neuropathol. Exp. Neurol. 53:1994;438-447.
35. Shin R. -W., Ogomori K., Kitamoto T., Tateishi J. Increased tau accumulation in senile plaques as a hallmark in Alzheimer's disease. Am. J. Pathol. 134:1989;1365-1371.
36. Smith M. A., Taneda S., Richey P. L., Miyata S., Yan S. -D., Stern D., Sayre L. M., Monnier V. M., Perry G. Advanced Maillard reaction products are associated with Alzheimer disease pathology. Proc. Natl. Acad. Sci. USA. 91:1994;5710-5714.
37. Terry R. D., Masliah E., Salmon D., Butters N., DeTeresa R., Hill R., Hansen L., Katzman R. Physical basis of cognitive alterations in Alzheimer's disease Synapse loss is the major correlate of cognitive impairment . Ann. Neurol. 30:1991;572-580.
38. Tomlinson B. E., Blessed G., Roth M. Observations on the brains of non-demented old people. J. Neurol. Sci. 7:1968;331-356.
39. Wang D., Munoz D. G. Qualitative and quantitative differences in senile plaque dystrophic neurites of Alzheimer's disease and normal aged brain. J. Neuropathol. Exp. Neurol. 54:1995;548-556.
40. Yen S. -H., Liu W. -K., Hall F. L., Yan S. -D., Stern D., Dickson D. W. Alzheimer neurofibrillary lesions Molecular nature and potential roles of differet components . Neurobiol. Aging. 16:1995;381-387.