An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-β derivatives

Journal of Neuroscience

Volumn 24, Issue 28, 2004, Pages 6277-6282

  Sigurdsson, Einar M ^a   Knudsen, Elin ^a   Asuni, Ayodeji ^a   Fitzer Attas, Cheryl ^b   Sage, Daniel ^a   Quartermain, David ^a   Goni, Fernando ^a,c   Frangione, Blas ^a   Wisniewski, Thomas ^a,d  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Mindset BioPharmaceuticals   (Israel)

^c UNIVERSITY OF URUGUAY   (Uruguay)

^d Millhauser Laboratories   (United States)

Author keywords

Alzheimer; Amyloid ; Behavior; Immunization; Immunoglobulin M; Transgenic mice

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-30]; AMYLOID BETA PROTEIN[1-42]; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; UNCLASSIFIED DRUG;

ALGORITHM; ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; COGNITION; CONTROLLED STUDY; DISEASE MODEL; DRUG SAFETY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MAZE TEST; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SENILE PLAQUE; TRANSGENIC MOUSE; VACCINATION;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE, TUMOR; CEREBRAL CORTEX; COGNITION; DISEASE MODELS, ANIMAL; FREUND'S ADJUVANT; HUMANS; IMMUNIZATION; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOTHERAPY, ACTIVE; MAZE LEARNING; MICE; MICE, TRANSGENIC; NEUROBLASTOMA; PEPTIDE FRAGMENTS; SENILE PLAQUES;

EID: 3242694207     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1344-04.2004     Document Type: Article

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