-
1
-
-
34047224186
-
Prior exercise increases phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle
-
doi:10.1152/ajpendo.00602.2006. PMID: 17179389
-
Arias, E.B., Kim, J., Funai, K., and Cartee, G. 2007. Prior exercise increases phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 292(4): E1191-E1200. doi:10.1152/ajpendo.00602.2006. PMID: 17179389.
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.292
, Issue.4
-
-
Arias, E.B.1
Kim, J.2
Funai, K.3
Cartee, G.4
-
2
-
-
57349091231
-
Divergent cell signaling after shortterm intensified endurance training in human skeletal muscle
-
doi:10.1152/ajpendo.90428.2008. PMID:18827172
-
Benziane, B., Burton, T.J., Scanlan, B., Galuska, D., Canny, B.J., Chibalin, A.V., et al. 2008. Divergent cell signaling after shortterm intensified endurance training in human skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 295(6): E1427-E1438. doi:10.1152/ajpendo.90428.2008. PMID:18827172.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
, Issue.6
-
-
Benziane, B.1
Burton, T.J.2
Scanlan, B.3
Galuska, D.4
Canny, B.J.5
Chibalin, A.V.6
-
3
-
-
0036298262
-
Rapamycin partially prevents insulin resistance induced by chronic insulin treatment
-
doi:10.1016/S0006-291X(02)00333-9. PMID:12051762
-
Berg, C.E., Lavan, B.E., and Rondinone, C.M. 2002. Rapamycin partially prevents insulin resistance induced by chronic insulin treatment. Biochem. Biophys. Res. Commun. 293(3): 1021-1027. doi:10.1016/S0006-291X(02)00333-9. PMID:12051762.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, Issue.3
, pp. 1021-1027
-
-
Berg, C.E.1
Lavan, B.E.2
Rondinone, C.M.3
-
4
-
-
56749096054
-
Translational control of localized mRNAs: restricting protein synthesis in space and time
-
doi:10.1038/nrm2548. PMID:19023284
-
Besse, F., and Ephrussi, A. 2008. Translational control of localized mRNAs: restricting protein synthesis in space and time. Nat. Rev. Mol. Cell Biol. 9(12): 971-980. doi:10.1038/nrm2548. PMID:19023284.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, Issue.12
, pp. 971-980
-
-
Besse, F.1
Ephrussi, A.2
-
5
-
-
34047095297
-
The two TORCs and Akt
-
doi:10.1016/j.devcel.2007.03.020. PMID: 17419990
-
Bhaskar, P.T., and Hay, N. 2007. The two TORCs and Akt. Dev. Cell, 12(4): 487-502. doi:10.1016/j.devcel.2007.03.020. PMID: 17419990.
-
(2007)
Dev. Cell
, vol.12
, Issue.4
, pp. 487-502
-
-
Bhaskar, P.T.1
Hay, N.2
-
6
-
-
18044393626
-
Insulin signal transduction in human skeletal muscle: identifying the defects in Type II diabetes
-
Pt. 2: doi:10.1042/BST0330354. PMID:15787605
-
Bjornholm, M., and Zierath, J.R. 2005. Insulin signal transduction in human skeletal muscle: identifying the defects in Type II diabetes. Biochem. Soc. Trans. 33(Pt. 2): 354-357. doi:10.1042/BST0330354. PMID:15787605.
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 354-357
-
-
Bjornholm, M.1
Zierath, J.R.2
-
7
-
-
0344033820
-
Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle
-
Pt. 1. doi:10.1113/jphysiol.2003.047019. PMID:12937293
-
Bolster, D.R., Kubica, N., Crozier, S.J., Williamson, D.L., Farrell, P.A., Kimball, S.R., and Jefferson, L.S. 2003. Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle. J. Physiol. 553(Pt. 1): 213-220. doi:10.1113/jphysiol.2003.047019. PMID:12937293.
-
(2003)
J. Physiol.
, vol.553
, pp. 213-220
-
-
Bolster, D.R.1
Kubica, N.2
Crozier, S.J.3
Williamson, D.L.4
Farrell, P.A.5
Kimball, S.R.6
Jefferson, L.S.7
-
8
-
-
33745668478
-
siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle
-
doi:10.1016/j.cmet.2006.04.008. PMID: 16814735
-
Bouzakri, K., Zachrisson, A., Al-Khalili, L., Zhang, B.B., Koistinen, H.A., Krook, A., and Zierath, J.R. 2006. siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. Cell Metab. 4(1): 89-96. doi:10.1016/j.cmet.2006.04.008. PMID: 16814735.
-
(2006)
Cell Metab
, vol.4
, Issue.1
, pp. 89-96
-
-
Bouzakri, K.1
Zachrisson, A.2
Al-Khalili, L.3
Zhang, B.B.4
Koistinen, H.A.5
Krook, A.6
Zierath, J.R.7
-
9
-
-
53449092586
-
A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression
-
doi:10.1152/ajpcell.00554.2007. PMID:18650261
-
Buller, C.L., Loberg, R.D., Fan, M.-H., Zhu, Q., Park, J.L., Vesely, E., et al. 2008. A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression. Am. J. Physiol. Cell Physiol. 295(3): C836-C843. doi:10.1152/ajpcell.00554.2007. PMID:18650261.
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.295
, Issue.3
-
-
Buller, C.L.1
Loberg, R.D.2
Fan M.-H. Zhu, Q.3
Park, J.L.4
Vesely, E.5
-
10
-
-
33845968034
-
Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression
-
doi:10.1210/me.2006-0154. PMID: 17021050
-
Cleasby, M.E., Reinten, T.A., Cooney, G.J., James, D.E., and Kraegen, E.W. 2007. Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression. Mol. Endocrinol. 1(1): 215-228. doi:10.1210/me.2006-0154. PMID: 17021050.
-
(2007)
Mol. Endocrinol.
, vol.21
, Issue.1
, pp. 215-228
-
-
Cleasby, M.E.1
Reinten, T.A.2
Cooney, G.J.3
James, D.E.4
Kraegen, E.W.5
-
11
-
-
0030979722
-
Mechanism of impaired insulin-stimulated muscle glucose metabolism in subjects with insulin-dependent diabetes mellitus
-
doi:10.1172/JCI119395. PMID:9151794
-
Cline, G.W., Magnusson, I., Rothman, D., Petersen, K., Laurent, D., and Shulman, G. 1997. Mechanism of impaired insulin-stimulated muscle glucose metabolism in subjects with insulin-dependent diabetes mellitus. J. Clin. Invest. 99(9): 2219-2224. doi:10.1172/JCI119395. PMID:9151794.
-
(1997)
J. Clin. Invest.
, vol.99
, Issue.9
, pp. 2219-2224
-
-
Cline, G.W.1
Magnusson, I.2
Rothman, D.3
Petersen, K.4
Laurent, D.5
Shulman, G.6
-
12
-
-
34548371839
-
The molecular bases of training adaptation
-
doi:10.2165/00007256-200737090-00001. PMID:17722947
-
Coffey, V.G., and Hawley, J.A. 2007. The molecular bases of training adaptation. Sports Med. 37(9): 737-763. doi:10.2165/00007256-200737090-00001. PMID:17722947.
-
(2007)
Sports Med
, vol.37
, Issue.9
, pp. 737-763
-
-
Coffey, V.G.1
Hawley, J.A.2
-
13
-
-
66149104031
-
Consecutive bouts of diverse contractile activity alter acute responses in human skeletal muscle
-
doi:10.1152/japplphysiol.91221.2008. PMID:19164772
-
Coffey, V.G., Pilegaard, H., Garnham, A.P., O'Brien, B.J., and Hawley, J.A. 2009. Consecutive bouts of diverse contractile activity alter acute responses in human skeletal muscle. J. Appl. Physiol. 106(4): 1187-1197. doi:10.1152/japplphysiol.91221.2008. PMID:19164772.
-
(2009)
J. Appl. Physiol.
, vol.106
, Issue.4
, pp. 1187-1197
-
-
Coffey, V.G.1
Pilegaard, H.2
Garnham, A.P.3
O'Brien, B.J.4
Hawley, J.A.5
-
14
-
-
0141727765
-
Tissuespecific regulation of protein synthesis by insulin and free fatty acids
-
PMID:12837665
-
Crozier, S.J., Anthony, J.C., Schworer, C.M., Reiter, A.K., Anthony, T.G., Kimball, S.R., and Jefferson, L.S. 2003. Tissuespecific regulation of protein synthesis by insulin and free fatty acids. Am. J. Physiol. Endocrinol. Metab. 285(4): E754-E762. PMID:12837665.
-
(2003)
Am. J. Physiol. Endocrinol. Metab.
, vol.285
, Issue.4
-
-
Crozier, S.J.1
Anthony, J.C.2
Schworer, C.M.3
Reiter, A.K.4
Anthony, T.G.5
Kimball, S.R.6
Jefferson, L.S.7
-
15
-
-
0142024829
-
Sugars, insulin sensitivity, and the postprandial state
-
PMID:14522751
-
Daly, M. 2003. Sugars, insulin sensitivity, and the postprandial state. Am. J. Clin. Nutr. 78(4): 865S-872S. PMID:14522751.
-
(2003)
Am. J. Clin. Nutr.
, vol.78
, Issue.4
-
-
Daly, M.1
-
16
-
-
0035798097
-
Mammalian TOR: a homeostatic ATP sensor
-
doi:10.1126/science.1063518. PMID:11691993
-
Dennis, P.B., Jaeschke, A., Saitoh, M., Fowler, B., Kozma, S.C., and Thomas, G. 2001. Mammalian TOR: a homeostatic ATP sensor. Science, 294(5544): 1102-1105. doi:10.1126/science.1063518. PMID:11691993.
-
(2001)
Science
, vol.294
, Issue.5544
, pp. 1102-1105
-
-
Dennis, P.B.1
Jaeschke, A.2
Saitoh, M.3
Fowler, B.4
Kozma, S.C.5
Thomas, G.6
-
17
-
-
0032954778
-
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
-
doi:10.1172/JCI5001. PMID:9916137
-
Dresner, A., Laurent, D., Marcucci, M., Griffin, M.E., Dufour, S., Cline, G.W., et al. 1999. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J. Clin. Invest. 103(2): 253-259. doi:10.1172/JCI5001. PMID:9916137.
-
(1999)
J. Clin. Invest.
, vol.103
, Issue.2
, pp. 253-259
-
-
Dresner, A.1
Laurent, D.2
Marcucci, M.3
Griffin, M.E.4
Dufour, S.5
Cline, G.W.6
-
18
-
-
33749351995
-
Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle
-
doi:10.1113/jphysiol.2006.113175. PMID:16873412
-
Dreyer, H.C., Fujita, S., Cadenas, J.G., Chinkes, D.L., Volpi, E., and Rasmussen, B.B. 2006. Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle. J. Physiol. 576(2): 613-624. doi:10.1113/jphysiol.2006.113175. PMID:16873412.
-
(2006)
J. Physiol.
, vol.576
, Issue.2
, pp. 613-624
-
-
Dreyer, H.C.1
Fujita, S.2
Cadenas, J.G.3
Chinkes, D.L.4
Volpi, E.5
Rasmussen, B.B.6
-
19
-
-
57349197971
-
Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery
-
doi:10.1152/japplphysiol.90562.2008. PMID:18845784
-
Dreyer, H.C., Drummond, M.J., Glynn, E.L., Fujita, S., Chinkes, D.L., Volpi, E., and Rasmussen, B.B. 2008a. Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery. J. Appl. Physiol. 105(6): 1967-1974. doi:10.1152/japplphysiol.90562.2008. PMID:18845784.
-
(2008)
J. Appl. Physiol.
, vol.105
, Issue.6
, pp. 1967-1974
-
-
Dreyer, H.C.1
Drummond, M.J.2
Glynn, E.L.3
Fujita, S.4
Chinkes, D.L.5
Volpi, E.6
Rasmussen, B.B.7
-
20
-
-
38949126221
-
Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle
-
doi:10.1152/ajpendo.00582.2007. PMID:18056791
-
Dreyer, H.C., Drummond, M.J., Pennings, B., Fujita, S., Glynn, E.L., Chinkes, D.L., et al. 2008b. Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle. Am. J. Physiol. Endocrinol. Metab. 294(2): E392-E400. doi:10.1152/ajpendo.00582.2007. PMID:18056791.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.294
, Issue.2
-
-
Dreyer, H.C.1
Drummond, M.J.2
Pennings, B.3
Fujita, S.4
Glynn, E.L.5
Chinkes, D.L.6
-
21
-
-
45149131733
-
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging
-
doi:10.1152/japplphysiol.00021.2008. PMID:18323467
-
Drummond, M.J., Dreyer, H.C., Pennings, B., Fry, C.S., Dhanani, S., Dillon, E.L., et al. 2008. Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging. J. Appl. Physiol. 104(5): 1452-1461. doi:10.1152/japplphysiol.00021.2008. PMID:18323467.
-
(2008)
J. Appl. Physiol.
, vol.104
, Issue.5
, pp. 1452-1461
-
-
Drummond, M.J.1
Dreyer, H.C.2
Pennings, B.3
Fry, C.S.4
Dhanani, S.5
Dillon, E.L.6
-
22
-
-
0035976615
-
Phosphatidic acid-mediated mitogenic activation of mTOR signaling
-
doi:10.1126/science.1066015. PMID:11729323
-
Fang, Y., Vilella-Bach, M., Bachmann, R., Flanigan, A., and Chen, J. 2001. Phosphatidic acid-mediated mitogenic activation of mTOR signaling. Science, 294(5548): 1942-1945. doi:10.1126/science.1066015. PMID:11729323.
-
(2001)
Science
, vol.294
, Issue.5548
, pp. 1942-1945
-
-
Fang, Y.1
Vilella-Bach, M.2
Bachmann, R.3
Flanigan, A.4
Chen, J.5
-
23
-
-
0014669160
-
Plasma amino acid levels and insulin secretion in obesity
-
PMID:5809519
-
Felig, P., Marliss, E., and Cahill, G.F., Jr. 1969. Plasma amino acid levels and insulin secretion in obesity. N. Engl. J. Med. 281(15): 811-816. PMID:5809519.
-
(1969)
N. Engl. J. Med.
, vol.281
, Issue.15
, pp. 811-816
-
-
Felig, P.1
Marliss, E.2
Cahill G.F., Jr.3
-
24
-
-
0031887111
-
Amino acids stimulate phosphorylation of p70S6k and organization of rat adipocytes into multicellular clusters
-
PMID:9458729
-
Fox, H.L., Kimball, S.R., Jefferson, L.S., and Lynch, C.J. 1998a. Amino acids stimulate phosphorylation of p70S6k and organization of rat adipocytes into multicellular clusters. Am. J. Physiol. Cell Physiol. 274(1): C206-C213. PMID:9458729.
-
(1998)
Am. J. Physiol. Cell Physiol.
, vol.274
, Issue.1
-
-
Fox, H.L.1
Kimball, S.R.2
Jefferson, L.S.3
Lynch, C.J.4
-
25
-
-
0031730304
-
Amino acid effects on translational repressor 4EBP1 are mediated primarily by L-leucine in isolated adipocytes
-
PMID:9814971
-
Fox, H.L., Pham, P.T., Kimball, S.R., Jefferson, L.S., and Lynch, C.J. 1998b. Amino acid effects on translational repressor 4EBP1 are mediated primarily by L-leucine in isolated adipocytes. Am. J. Physiol. Cell Physiol. 275(5): C1232-C1238. PMID:9814971.
-
(1998)
Am. J. Physiol. Cell Physiol.
, vol.275
, Issue.5
-
-
Fox, H.L.1
Pham, P.T.2
Kimball, S.R.3
Jefferson, L.S.4
Lynch, C.J.5
-
26
-
-
33748471980
-
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s
-
doi:10.1016/j.cub.2006.08.001. PMID:16919458
-
Frias, M.A., Thoreen, C.C., Jaffe, J.D., Schroder, W., Sculley, T., Carr, S.A., and Sabatini, D.M. 2006. mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Curr. Biol. 16(18): 1865-1870. doi:10.1016/j.cub.2006.08.001. PMID:16919458.
-
(2006)
Curr. Biol.
, vol.16
, Issue.18
, pp. 1865-1870
-
-
Frias, M.A.1
Thoreen, C.C.2
Jaffe, J.D.3
Schroder, W.4
Sculley, T.5
Carr, S.A.6
Sabatini, D.M.7
-
27
-
-
34547570876
-
Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160
-
doi:10.2337/db06-1698. PMID:17513702
-
Frosig, C., Rose, A.J., Treebak, J.T., Kiens, B., Richter, E.A., and Wojtaszewski, J.F. 2007. Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160. Diabetes, 56(8): 2093-2102. doi:10.2337/db06-1698. PMID:17513702.
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 2093-2102
-
-
Frosig, C.1
Rose, A.J.2
Treebak, J.T.3
Kiens, B.4
Richter, E.A.5
Wojtaszewski, J.F.6
-
28
-
-
34249678700
-
Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling
-
doi:10.2337/db06-1566. PMID:17351147
-
Fujita, S., Rasmussen, B.B., Cadenas, J.G., Drummond, M.J., Glynn, E.L., Sattler, F.R., and Volpi, E. 2007. Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling. Diabetes, 56(6): 1615-1622. doi:10.2337/db06-1566. PMID:17351147.
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1615-1622
-
-
Fujita, S.1
Rasmussen, B.B.2
Cadenas, J.G.3
Drummond, M.J.4
Glynn, E.L.5
Sattler, F.R.6
Volpi, E.7
-
29
-
-
0038433304
-
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
-
doi:10.1016/S1097-2765(03)00220-X. PMID:12820960
-
Garami, A., Zwartkruis, F.J., Nobukuni, T., Joaquin, M., Roccio, M., Stocker, H., et al. 2003. Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Mol. Cell, 11(6): 1457-1466. doi:10.1016/S1097-2765(03)00220-X. PMID:12820960.
-
(2003)
Mol. Cell
, vol.11
, Issue.6
, pp. 1457-1466
-
-
Garami, A.1
Zwartkruis, F.J.2
Nobukuni, T.3
Joaquin, M.4
Roccio, M.5
Stocker, H.6
-
30
-
-
0035904293
-
Rapamycin's resurrection: a new way to target the cancer cell cycle
-
PMID:11604470
-
Garber, K. 2001. Rapamycin's resurrection: a new way to target the cancer cell cycle. J. Natl. Cancer Inst. 93(20): 1517-1519. PMID:11604470.
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, Issue.20
, pp. 1517-1519
-
-
Garber, K.1
-
31
-
-
39749190584
-
A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle
-
doi:10.1139/H07-149. PMID:18347658
-
Glynn, E.L., Lujan, H.L., Kramer, V.J., Drummond, M.J., DiCarlo, S.E., and Rasmussen, B.B. 2008. A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle. Appl. Physiol. Nutr. Metab. 33(1): 93-101. doi:10.1139/H07-149. PMID:18347658.
-
(2008)
Appl. Physiol. Nutr. Metab.
, vol.33
, Issue.1
, pp. 93-101
-
-
Glynn, E.L.1
Lujan, H.L.2
Kramer, V.J.3
Drummond, M.J.4
DiCarlo, S.E.5
Rasmussen, B.B.6
-
32
-
-
68149096799
-
The pharmacology of mTOR inhibition
-
PMID:19383975
-
Guertin, D.A., and Sabatini, D.M. 2009. The pharmacology of mTOR inhibition. Sci. Signal. 2(67): pe24. PMID:19383975.
-
(2009)
Sci. Signal.
, Issue.67
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
33
-
-
34247120977
-
Nutrient sensing in the mTOR/S6K1 signalling pathway
-
Pt. 2, doi:10.1042/BST0350236. PMID:17371247
-
Gulati, P., and Thomas, G. 2007. Nutrient sensing in the mTOR/S6K1 signalling pathway. Biochem. Soc. Trans. 35(Pt. 2): 236-238. doi:10.1042/BST0350236. PMID:17371247.
-
(2007)
Biochem. Soc. Trans.
, vol.5
, pp. 236-238
-
-
Gulati, P.1
Thomas, G.2
-
34
-
-
42649112409
-
Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34
-
doi:10.1016/j.cmet.2008.03.002. PMID:18460336
-
Gulati, P., Gaspers, L.D., Dann, S.G., Joaquin, M., Nobukuni, T., Natt, F., et al. 2008. Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. Cell Metab. 7(5): 456-465. doi:10.1016/j.cmet.2008.03.002. PMID:18460336.
-
(2008)
Cell Metab
, vol.7
, Issue.5
, pp. 456-465
-
-
Gulati, P.1
Gaspers, L.D.2
Dann, S.G.3
Joaquin, M.4
Nobukuni, T.5
Natt, F.6
-
35
-
-
0242637318
-
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF
-
doi:10.1128/MCB.23.23.8862-8877.2003. PMID:14612424
-
Hannan, K.M., Brandenburger, Y., Jenkins, A., Sharkey, K., Cavanaugh, A., Rothblum, L., et al. 2003. mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF. Mol. Cell. Biol. 23(23): 8862-8877. doi:10.1128/MCB.23.23.8862-8877.2003. PMID:14612424.
-
(2003)
Mol. Cell. Biol.
, vol.23
, Issue.23
, pp. 8862-8877
-
-
Hannan, K.M.1
Brandenburger, Y.2
Jenkins, A.3
Sharkey, K.4
Cavanaugh, A.5
Rothblum, L.6
-
36
-
-
0032486268
-
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
-
doi:10.1074/jbc.273.23.14484. PMID:9603962
-
Hara, K., Yonezawa, K., Weng, Q.-P., Kozlowski, M.T., Belham, C., and Avruch, J. 1998. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J. Biol. Chem. 273(23): 14484-14494. doi:10.1074/jbc.273.23.14484. PMID:9603962.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.23
, pp. 14484-14494
-
-
Hara, K.1
Yonezawa, K.2
Weng Q.-P. Kozlowski, M.T.3
Belham, C.4
Avruch, J.5
-
37
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
doi:10.1016/S0092-8674(02)00833-4. PMID:12150926
-
Hara, K., Maruki, Y., Long, X., Yoshino, K., Oshiro, N., Hidayat, S., et al. 2002. Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell, 110(2): 177-189. doi:10.1016/S0092-8674(02)00833-4. PMID:12150926.
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.4
Oshiro, N.5
Hidayat, S.6
-
38
-
-
37249066135
-
Exercise training-induced improvements in insulin action
-
PMID:18171435
-
Hawley, J.A., and Lessard, S.J. 2008. Exercise training-induced improvements in insulin action. Acta Physiol. (Oxf.), 192(1): 127-135. PMID:18171435.
-
(2008)
Acta Physiol. (Oxf.)
, vol.192
, Issue.1
, pp. 127-135
-
-
Hawley, J.A.1
Lessard, S.J.2
-
39
-
-
4043171462
-
Upstream and downstream of mTOR
-
doi:10.1101/gad.1212704. PMID:15314020
-
Hay, N., and Sonenberg, N. 2004. Upstream and downstream of mTOR. Genes Dev. 18(16): 1926-1945. doi:10.1101/gad.1212704. PMID:15314020.
-
(2004)
Genes Dev
, vol.18
, Issue.16
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
40
-
-
0025776523
-
Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast
-
doi:10.1126/science.1715094. PMID:1715094
-
Heitman, J., Movva, N.R., and Hall, M.N. 1991. Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science, 253(5022): 905-909. doi:10.1126/science.1715094. PMID:1715094.
-
(1991)
Science
, vol.253
, Issue.5022
, pp. 905-909
-
-
Heitman, J.1
Movva, N.R.2
Hall, M.N.3
-
41
-
-
0842310044
-
Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes
-
doi:10.2337/diabetes.53.2.294. PMID:14747278
-
Holten, M.K., Zacho, M., Gaster, M., Juel, C., Wojtaszewski, J.F., and Dela, F. 2004. Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes, 53(2): 294-305. doi:10.2337/diabetes.53.2.294. PMID:14747278.
-
(2004)
Diabetes
, vol.53
, Issue.2
, pp. 294-305
-
-
Holten, M.K.1
Zacho, M.2
Gaster, M.3
Juel, C.4
Wojtaszewski, J.F.5
Dela, F.6
-
42
-
-
33746622168
-
Regulation of mTOR by mechanically induced signaling events in skeletal muscle
-
PMID:16855395
-
Hornberger, T.A., Sukhija, K.B., and Chien, S. 2006a. Regulation of mTOR by mechanically induced signaling events in skeletal muscle. Cell Cycle, 5(13): 1391-1396. PMID:16855395.
-
(2006)
Cell Cycle
, vol.5
, Issue.13
, pp. 1391-1396
-
-
Hornberger, T.A.1
Sukhija, K.B.2
Chien, S.3
-
43
-
-
33645241260
-
The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle
-
doi:10.1073/pnas.0600678103. PMID:16537399
-
Hornberger, T.A., Chu, W.K., Mak, Y.W., Hsiung, J.W., Huang, S.A., and Chien, S. 2006b. The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle. Proc. Natl. Acad. Sci. U.S.A. 103(12): 4741-4746. doi:10.1073/pnas.0600678103. PMID:16537399.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, Issue.12
, pp. 4741-4746
-
-
Hornberger, T.A.1
Chu, W.K.2
Mak, Y.W.3
Hsiung, J.W.4
Huang, S.A.5
Chien, S.6
-
44
-
-
34548693675
-
mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k)
-
doi:10.1016/j.febslet.2007.08.045. PMID:17825298
-
Hornberger, T.A., Sukhija, K.B., Wang, X.R., and Chien, S. 2007. mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k). FEBS Lett. 581(24): 4562-4566. doi:10. 1016/j.febslet.2007.08.045. PMID:17825298.
-
(2007)
FEBS Lett
, vol.581
, Issue.24
, pp. 4562-4566
-
-
Hornberger, T.A.1
Sukhija, K.B.2
Wang, X.R.3
Chien, S.4
-
45
-
-
0347993713
-
Effect of the volume and intensity of exercise training on insulin sensitivity
-
doi:10.1152/japplphysiol.00707.2003. PMID:12972442
-
Houmard, J.A., Tanner, C.J., Slentz, C.A., Duscha, B.D., McCartney, J.S., and Kraus, W.E. 2004. Effect of the volume and intensity of exercise training on insulin sensitivity. J. Appl. Physiol. 96(1): 101-106. doi:10.1152/japplphysiol.00707.2003. PMID:12972442.
-
(2004)
J. Appl. Physiol.
, vol.96
, Issue.1
, pp. 101-106
-
-
Houmard, J.A.1
Tanner, C.J.2
Slentz, C.A.3
Duscha, B.D.4
McCartney, J.S.5
Kraus, W.E.6
-
46
-
-
38949103750
-
The effect of exercise and insulin on AS160 phosphorylation and 14-3-3 binding capacity in human skeletal muscle
-
doi:10.1152/ajpendo.00542.2007. PMID:18042670
-
Howlett, K.F., Mathews, A., Garnham, A., and Sakamoto, K. 2008. The effect of exercise and insulin on AS160 phosphorylation and 14-3-3 binding capacity in human skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 294(2): E401-E407. doi:10.1152/ajpendo.00542.2007. PMID:18042670.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.294
, Issue.2
-
-
Howlett, K.F.1
Mathews, A.2
Garnham, A.3
Sakamoto, K.4
-
47
-
-
28844434558
-
mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes
-
doi:10.1074/jbc.M508361200. PMID:16221682
-
Hresko, R.C., and Mueckler, M. 2005. mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. J. Biol. Chem. 280(49): 40406-40416. doi:10.1074/jbc.M508361200. PMID:16221682.
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.49
, pp. 40406-40416
-
-
Hresko, R.C.1
Mueckler, M.2
-
48
-
-
65649152957
-
Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling
-
doi:10.1152/ajpendo.91002.2008. PMID:19158318
-
Hundal, H.S., and Taylor, P.M. 2009. Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling. Am. J. Physiol. Endocrinol. Metab. 296(4): E603-E613. doi:10.1152/ajpendo.91002.2008. PMID:19158318.
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.296
, Issue.4
-
-
Hundal, H.S.1
Taylor, P.M.2
-
49
-
-
0031902198
-
Resistance training improves insulin sensitivity in NIDDM subjects without altering maximal oxygen uptake
-
doi:10.2337/diacare.21.8.1353. PMID:9702447
-
Ishii, T., Yamakita, T., Sato, T., Tanaka, S., and Fujii, S. 1998. Resistance training improves insulin sensitivity in NIDDM subjects without altering maximal oxygen uptake. Diabetes Care, 21(8): 1353-1355. doi:10.2337/diacare.21.8.1353. PMID:9702447.
-
(1998)
Diabetes Care
, vol.21
, Issue.8
, pp. 1353-1355
-
-
Ishii, T.1
Yamakita, T.2
Sato, T.3
Tanaka, S.4
Fujii, S.5
-
50
-
-
7944235758
-
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
-
doi:10.1038/ncb1183. PMID:15467718.
-
Jacinto, E., Loewith, R., Schmidt, A., Lin, S., Ruegg, M.A., Hall, A., and Hall, M.N. 2004. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat. Cell Biol. 6(11): 1122-1128. doi:10.1038/ncb1183. PMID:15467718.
-
(2004)
Nat. Cell Biol.
, vol.6
, Issue.11
, pp. 1122-1128
-
-
Jacinto, E.1
Loewith, R.2
Schmidt, A.3
Lin, S.4
Ruegg, M.A.5
Hall, A.6
Hall, M.N.7
-
51
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
doi:10.1016/j.cell.2006.08.033. PMID:16962653
-
Jacinto, E., Facchinetti, V., Liu, D., Soto, N., Wei, S., Jung, S.Y., et al. 2006. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell, 127(1): 125-137. doi:10.1016/j.cell.2006.08.033. PMID:16962653.
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
Soto, N.4
Wei, S.5
Jung, S.Y.6
-
52
-
-
37549028779
-
Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function
-
doi:10.1080/08977190701779101. PMID:18092230
-
Jastrzebski, K., Hannan, K.M., Tchoubrieva, E.B., Hannan, R.D., and Pearson, R.B. 2007. Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function. Growth Factors, 25(4): 209-226. doi:10.1080/08977190701779101. PMID:18092230.
-
(2007)
Growth Factors,
, vol.25
, Issue.4
, pp. 209-226
-
-
Jastrzebski, K.1
Hannan, K.M.2
Tchoubrieva, E.B.3
Hannan, R.D.4
Pearson, R.B.5
-
53
-
-
0033849777
-
Obesity and insulin resistance
-
doi:10.1172/JCI10842. PMID:10953022
-
Kahn, B.B., and Flier, J.S. 2000. Obesity and insulin resistance. J. Clin. Invest. 106(4): 473-481. doi:10.1172/JCI10842. PMID:10953022.
-
(2000)
J. Clin. Invest.
, vol.106
, Issue.4
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
54
-
-
14244256097
-
Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance
-
doi:10.1210/en.2004-0921. PMID:15604215
-
Khamzina, L., Veilleux, A., Bergeron, S., and Marette, A. 2005. Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance. Endocrinology, 146(3): 1473-1481. doi:10.1210/en.2004-0921. PMID:15604215.
-
(2005)
Endocrinology
, vol.146
, Issue.3
, pp. 1473-1481
-
-
Khamzina, L.1
Veilleux, A.2
Bergeron, S.3
Marette, A.4
-
55
-
-
0034085886
-
Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats
-
doi:10.2337/diabetes.49.5.847. PMID:10905496
-
Kim, Y.B., Peroni, O.D., Franke, T.F., and Kahn, B.B. 2000. Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats. Diabetes, 49(5): 847-856. doi:10.2337/diabetes.49.5.847. PMID:10905496.
-
(2000)
Diabetes
, vol.49
, Issue.5
, pp. 847-856
-
-
Kim, Y.B.1
Peroni, O.D.2
Franke, T.F.3
Kahn, B.B.4
-
56
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
doi:10.1016/S00928674(02)00808-5. PMID:12150925
-
Kim, D.-H., Sarbassov, D.D., Ali, S.M., King, J.E., Latek, R.R., Erdjument-Bromage, H., et al. 2002. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell, 110(2): 163-175. doi:10.1016/S00928674(02)00808-5. PMID:12150925.
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 163-175
-
-
Kim D.-H. Sarbassov, D.D.1
Ali, S.M.2
King, J.E.3
Latek, R.R.4
Erdjument-Bromage, H.5
-
57
-
-
34548081433
-
Protein ingestion further augments S6K1 phosphorylation in skeletal muscle following resistance type exercise in males
-
PMID:17634259
-
Koopman, R., Pennings, B., Zorenc, A.H.G., and van Loon, L.J.C. 2007. Protein ingestion further augments S6K1 phosphorylation in skeletal muscle following resistance type exercise in males. J. Nutr. 137(8): 1880-1886. PMID:17634259.
-
(2007)
J. Nutr.
, vol.137
, Issue.8
, pp. 1880-1886
-
-
Koopman, R.1
Pennings, B.2
Zorenc, A.H.G.3
van Loon, L.J.C.4
-
58
-
-
33750922694
-
Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice
-
doi:10.1007/s00125-006-0439-5. PMID:17006666
-
Korsheninnikova, E., van der Zon, G.C., Voshol, P.J., Janssen, G.M., Havekes, L.M., Grefhorst, A., et al. 2006. Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice. Diabetologia, 49(12): 3049-3057. doi:10.1007/s00125-006-0439-5. PMID:17006666.
-
(2006)
Diabetologia
, vol.49
, Issue.12
, pp. 3049-3057
-
-
Korsheninnikova, E.1
van der Zon, G.C.2
Voshol, P.J.3
Janssen, G.M.4
Havekes, L.M.5
Grefhorst, A.6
-
59
-
-
33845998942
-
AS160 regulates insulin-and contraction-stimulated glucose uptake in mouse skeletal muscle
-
doi:10.1074/jbc.M605461200. PMID:16935857
-
Kramer, H.F., Witczak, C., Taylor, E., Fujii, N., Hirshman, M., and Goodyear, L. 2006. AS160 regulates insulin-and contraction-stimulated glucose uptake in mouse skeletal muscle. J. Biol. Chem. 281(42): 31478-31485. doi:10.1074/jbc.M605461200. PMID:16935857.
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.42
, pp. 31478-31485
-
-
Kramer, H.F.1
Witczak, C.2
Taylor, E.3
Fujii, N.4
Hirshman, M.5
Goodyear, L.6
-
60
-
-
1842534924
-
Nutrient-induced insulin resistance in human skeletal muscle
-
doi:10.2174/0929867043455620. PMID:15078172
-
Krebs, M., and Roden, M. 2004. Nutrient-induced insulin resistance in human skeletal muscle. Curr. Med. Chem. 11(7): 901-908. doi:10.2174/0929867043455620. PMID:15078172.
-
(2004)
Curr. Med. Chem.
, vol.11
, Issue.7
, pp. 901-908
-
-
Krebs, M.1
Roden, M.2
-
61
-
-
0036313574
-
Mechanism of amino acid-induced skeletal muscle insulin resistance in humans
-
doi:10.2337/diabetes.51.3.599. PMID:11872656
-
Krebs, M., Krssak, M., Bernroider, E., Anderwald, C., Brehm, A., Meyerspeer, M., et al. 2002. Mechanism of amino acid-induced skeletal muscle insulin resistance in humans. Diabetes, 51(3): 599-605. doi:10.2337/diabetes.51.3.599. PMID:11872656.
-
(2002)
Diabetes
, vol.51
, Issue.3
, pp. 599-605
-
-
Krebs, M.1
Krssak, M.2
Bernroider, E.3
Anderwald, C.4
Brehm, A.5
Meyerspeer, M.6
-
62
-
-
34249679233
-
The mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man
-
doi:10.2337/db06-1016. PMID:17329620
-
Krebs, M., Brunmair, B., Brehm, A., Artwohl, M., Szendroedi, J., Nowotny, P., et al. 2007. The mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man. Diabetes, 56(6): 1600-1607. doi:10.2337/db06-1016. PMID:17329620.
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1600-1607
-
-
Krebs, M.1
Brunmair, B.2
Brehm, A.3
Artwohl, M.4
Szendroedi, J.5
Nowotny, P.6
-
63
-
-
37549000623
-
Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity
-
doi:10.1128/MCB.01405-07. PMID:17967879
-
Kumar, A., Harris, T.E., Keller, S.R., Choi, K.M., Magnuson, M.A., and Lawrence, J.C., Jr. 2008. Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity. Mol. Cell. Biol. 28(1): 61-70. doi:10.1128/MCB.01405-07. PMID:17967879.
-
(2008)
Mol. Cell. Biol.
, vol.28
, Issue.1
, pp. 61-70
-
-
Kumar, A.1
Harris, T.E.2
Keller, S.R.3
Choi, K.M.4
Magnuson, M.A.5
Lawrence J.C., Jr.6
-
64
-
-
33748452108
-
Elevated plasma free fatty acids decrease basal protein synthesis, but not the anabolic effect of leucine, in skeletal muscle
-
doi:10.1152/ajpendo.00065.2006. PMID:16684854
-
Lang, C.H. 2006. Elevated plasma free fatty acids decrease basal protein synthesis, but not the anabolic effect of leucine, in skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 291(3): E666-E674. doi:10.1152/ajpendo.00065.2006. PMID:16684854.
-
(2006)
Am. J. Physiol. Endocrinol. Metab.
, vol.291
, Issue.3
-
-
Lang, C.H.1
-
65
-
-
33750400410
-
Akt signalling through GSK-3, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy
-
doi:10.1113/jphysiol.2006.116715. PMID:16916907
-
Leger, B., Cartoni, R., Praz, M., Lamon, S., Deriaz, O., Crettenand, A., et al. 2006. Akt signalling through GSK-3, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy. J. Physiol. 576(3): 923-933. doi:10.1113/jphysiol.2006.116715. PMID:16916907.
-
(2006)
J. Physiol.
, vol.576
, Issue.3
, pp. 923-933
-
-
Leger, B.1
Cartoni, R.2
Praz, M.3
Lamon, S.4
Deriaz, O.5
Crettenand, A.6
-
66
-
-
34347390598
-
Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance
-
doi:10.2337/db06-1065. PMID:17440174
-
Lessard, S.J., Rivas, D.A., Chen, Z.-P., Bonen, A., Febbraio, M.A., Reeder, D.W., et al. 2007. Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance. Diabetes, 56(7): 1856-1864. doi:10.2337/db06-1065. PMID:17440174.
-
(2007)
Diabetes
, vol.56
, Issue.7
, pp. 1856-1864
-
-
Lessard, S.J.1
Rivas, D.A.2
Chen Z.-P. Bonen, A.3
Febbraio, M.A.4
Reeder, D.W.5
-
67
-
-
58149287669
-
mVps34 is activated following high-resistance contractions
-
Pt. 1: doi:10.1113/jphysiol.2008.159830. PMID:19015198
-
MacKenzie, M.G., Hamilton, D., Murray, J., Taylor, P., and Baar, K. 2009. mVps34 is activated following high-resistance contractions. J. Physiol. 87(Pt. 1): 253-260. doi:10.1113/jphysiol.2008.159830. PMID:19015198.
-
(2009)
J. Physiol.
, vol.87
, pp. 253-260
-
-
MacKenzie, M.G.1
Hamilton, D.2
Murray, J.3
Taylor, P.4
Baar, K.5
-
68
-
-
0036385637
-
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways
-
doi:10.1016/S0065-230X(02)86001-8. PMID:12374276
-
Martin, K.A., and Blenis, J. 2002. Coordinate regulation of translation by the PI 3-kinase and mTOR pathways. Adv. Cancer Res. 86: 1-39. doi:10.1016/S0065-230X(02)86001-8. PMID:12374276.
-
(2002)
Adv. Cancer Res.
, vol.86
, pp. 1-39
-
-
Martin, K.A.1
Blenis, J.2
-
69
-
-
34547683916
-
Changes in signalling pathways regulating protein synthesis in human muscle in the recovery period after endurance exercise
-
doi:10.1111/j.1748-1716.2007.01712.x. PMID:17488244
-
Mascher, H., Andersson, H., Nilsson, P.A., Ekblom, B., and Blomstrand, E. 2007. Changes in signalling pathways regulating protein synthesis in human muscle in the recovery period after endurance exercise. Acta Physiol. (Oxf.), 191(1): 67-75. doi:10.1111/j.1748-1716.2007.01712.x. PMID:17488244.
-
(2007)
Acta Physiol. (Oxf.)
, vol.191
, Issue.1
, pp. 67-75
-
-
Mascher, H.1
Andersson, H.2
Nilsson, P.A.3
Ekblom, B.4
Blomstrand, E.5
-
70
-
-
38349043742
-
Repeated resistance exercise training induces different changes in mRNA expression of MAFbx and MuRF-1 in human skeletal muscle
-
doi:10.1152/ajpendo.00504.2007. PMID:17971512
-
Mascher, H., Tannerstedt, J., Brink-Elfegoun, T., Ekblom, B., Gustafsson, T., and Blomstrand, E. 2008. Repeated resistance exercise training induces different changes in mRNA expression of MAFbx and MuRF-1 in human skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 294(1): E43-E51. doi:10.1152/ajpendo.00504.2007. PMID:17971512.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.294
, Issue.1
-
-
Mascher, H.1
Tannerstedt, J.2
Brink-Elfegoun, T.3
Ekblom, B.4
Gustafsson, T.5
Blomstrand, E.6
-
71
-
-
0036894449
-
Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance
-
PMID:12450892
-
McCullough, M.L., Feskanich, D., Stampfer, M.J., Giovannucci, E.L., Rimm, E.B., Hu, F.B., et al. 2002. Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance. Am. J. Clin. Nutr. 76(6): 1261-1271. PMID:12450892.
-
(2002)
Am. J. Clin. Nutr.
, vol.76
, Issue.6
, pp. 1261-1271
-
-
McCullough, M.L.1
Feskanich, D.2
Stampfer, M.J.3
Giovannucci, E.L.4
Rimm, E.B.5
Hu, F.B.6
-
72
-
-
34548092167
-
Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes
-
doi:10.1016/j.bbrc.2007.08.004. PMID:17698034
-
Mordier, S., and Iynedjian, P.B. 2007. Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes. Biochem. Biophys. Res. Commun. 362(1): 206-211. doi:10.1016/j.bbrc.2007.08.004. PMID:17698034.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.362
, Issue.1
, pp. 206-211
-
-
Mordier, S.1
Iynedjian, P.B.2
-
73
-
-
27744549321
-
mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators
-
doi:10.1152/ajpcell.00165.2005. PMID:16079186
-
Nader, G.A., McLoughlin, T.J., and Esser, K.A. 2005. mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators. Am. J. Physiol. Cell Physiol. 289(6): -. doi:10.1152/ajpcell.00165.2005. PMID:16079186.
-
(2005)
Am. J. Physiol. Cell Physiol.
, vol.289
, Issue.6
-
-
Nader, G.A.1
McLoughlin, T.J.2
Esser, K.A.3
-
74
-
-
26444575415
-
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OHkinase
-
doi:10.1073/pnas.0506925102. PMID:16176982
-
Nobukuni, T., Joaquin, M., Roccio, M., Dann, S.G., Kim, S.Y., Gulati, P., et al. 2005. Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OHkinase. Proc. Natl. Acad. Sci. U.S.A. 102(40): 14238-14243. doi:10.1073/pnas.0506925102. PMID:16176982.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, Issue.40
, pp. 14238-14243
-
-
Nobukuni, T.1
Joaquin, M.2
Roccio, M.3
Dann, S.G.4
Kim, S.Y.5
Gulati, P.6
-
75
-
-
0001437616
-
Bidirectional modulation of insulin action by amino acids
-
doi:10.1172/JCI1326. PMID:9525995
-
Patti, M.-E., Brambilla, E., Luzi, L., Landaker, E.J., and Kahn, R.C. 1998. Bidirectional modulation of insulin action by amino acids. J. Clin. Invest. 101(7): 1519-1529. doi:10.1172/JCI1326. PMID:9525995.
-
(1998)
J. Clin. Invest.
, vol.101
, Issue.7
, pp. 1519-1529
-
-
Patti M.-E. Brambilla, E.1
Luzi, L.2
Landaker, E.J.3
Kahn, R.C.4
-
76
-
-
50049116472
-
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
-
doi:10.1016/j.cmet.2008.07.007. PMID:18762023
-
Porstmann, T., Santos, C.R., Griffiths, B., Cully, M., Wu, M., Leevers, S., et al. 2008. SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth. Cell Metab. 8(3): 224-236. doi:10.1016/j.cmet.2008.07.007. PMID:18762023.
-
(2008)
Cell Metab
, vol.8
, Issue.3
, pp. 224-236
-
-
Porstmann, T.1
Santos, C.R.2
Griffiths, B.3
Cully, M.4
Wu, M.5
Leevers, S.6
-
77
-
-
58149141517
-
Protein, amino acids and the control of food intake
-
doi:10.1097/MCO.0b013e32831b9e01. PMID:19057188
-
Potier, M., Darcel, N., and Tome, D. 2009. Protein, amino acids and the control of food intake. Curr. Opin. Clin. Nutr. Metab. Care, 12(1): 54-58. doi:10.1097/MCO.0b013e32831b9e01. PMID:19057188.
-
(2009)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.12
, Issue.1
, pp. 54-58
-
-
Potier, M.1
Darcel, N.2
Tome, D.3
-
78
-
-
52049106904
-
Cell growth control: mTOR takes on fat
-
doi:10.1016/j.molcel.2008.09.006. PMID:18922461
-
Powers, T. 2008. Cell growth control: mTOR takes on fat. Mol. Cell, 31(6): 775-776. doi:10.1016/j.molcel.2008.09.006. PMID:18922461.
-
(2008)
Mol. Cell
, vol.31
, Issue.6
, pp. 775-776
-
-
Powers, T.1
-
79
-
-
0014618879
-
Amino acid balance across tissues of the forearm in postabsorptive man. Effects of insulin at two dose levels
-
doi:10.1172/JCI106193. PMID:5355340
-
Pozefsky, T., Felig, P., Tobin, J.D., Soeldner, J.S., and Cahill, G.F., Jr. 1969. Amino acid balance across tissues of the forearm in postabsorptive man. Effects of insulin at two dose levels. J. Clin. Invest. 48(12): 2273-2282. doi:10.1172/JCI106193. PMID:5355340.
-
(1969)
J. Clin. Invest.
, vol.48
, Issue.12
, pp. 2273-2282
-
-
Pozefsky, T.1
Felig, P.2
Tobin, J.D.3
Soeldner, J.S.4
Cahill G.F., Jr.5
-
80
-
-
0032578998
-
Phosphorylation and activation of p70s6k by PDK1
-
doi:10.1126/science.279.5351.707. PMID:9445476
-
Pullen, N., Dennis, P.B., Andjelkovic, M., Dufner, A., Kozma, S.C., Hemmings, B.A., and Thomas, G. 1998. Phosphorylation and activation of p70s6k by PDK1. Science, 279(5351): 707-710. doi:10.1126/science.279.5351.707. PMID:9445476.
-
(1998)
Science
, vol.279
, Issue.5351
, pp. 707-710
-
-
Pullen, N.1
Dennis, P.B.2
Andjelkovic, M.3
Dufner, A.4
Kozma, S.C.5
Hemmings, B.A.6
Thomas, G.7
-
81
-
-
70349323414
-
Lipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5'-aminoimidazole-4-carboxamide-1-D-ribofuranoside
-
PMID:19574345
-
Rivas, D.A., Yaspelkis, B.B., III, Hawley, J.A., and Lessard, S.J. 2009. Lipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5'-aminoimidazole-4-carboxamide-1-D-ribofuranoside. J. Endocrinol. 202: 441-451. PMID: 19574345.
-
(2009)
J. Endocrinol.
, vol.202
, pp. 441-451
-
-
Rivas, D.A.1
Yaspelkis B.B.III2
Hawley, J.A.3
Lessard, S.J.4
-
82
-
-
0028000563
-
Differentiating glucose toxicity from glucose desensitization: a new message from the insulin gene
-
doi:10.2337/diabetes.43.9.1085. PMID:8070607
-
Robertson, R.P., Olson, L., and Zhang, H. 1994. Differentiating glucose toxicity from glucose desensitization: a new message from the insulin gene. Diabetes, 43(9): 1085-1089. doi:10.2337/diabetes.43.9.1085. PMID:8070607.
-
(1994)
Diabetes
, vol.43
, Issue.9
, pp. 1085-1089
-
-
Robertson, R.P.1
Olson, L.2
Zhang, H.3
-
83
-
-
44049092767
-
Signaling mechanisms in skeletal muscle: acute responses and chronic adaptations to exercise
-
doi:10.1002/iub.21. PMID:18380005
-
Röckl, K.S.C., Witczak, C.A., and Goodyear, L.J. 2008. Signaling mechanisms in skeletal muscle: acute responses and chronic adaptations to exercise. IUBMB Life, 60(3): 145-153. doi:10.1002/iub.21. PMID:18380005.
-
(2008)
IUBMB Life
, vol.60
, Issue.3
, pp. 145-153
-
-
Röckl, K.S.C.1
Witczak, C.A.2
Goodyear, L.J.3
-
84
-
-
33747819801
-
mTOR and cancer: insights into a complex relationship
-
doi:10.1038/nrc1974. PMID:16915295
-
Sabatini, D.M. 2006. mTOR and cancer: insights into a complex relationship. Nat. Rev. Cancer, 6(9): 729-734. doi:10.1038/nrc1974. PMID:16915295.
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.9
, pp. 729-734
-
-
Sabatini, D.M.1
-
85
-
-
0028239893
-
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
-
doi:10.1016/0092-8674(94)90570-3. PMID:7518356
-
Sabatini, D.M., Erdjument-Bromage, H., Lui, M., Tempst, P., and Snyder, S.H. 1994. RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell, 78(1): 35-43. doi:10.1016/0092-8674(94)90570-3. PMID:7518356.
-
(1994)
Cell
, vol.78
, Issue.1
, pp. 35-43
-
-
Sabatini, D.M.1
Erdjument-Bromage, H.2
Lui, M.3
Tempst, P.4
Snyder, S.H.5
-
86
-
-
36148932174
-
The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation
-
doi:10.1074/jbc.M704150200. PMID:17848569
-
Saito, T., Jones, C.C., Huang, S., Czech, M.P., and Pilch, P.F. 2007. The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation. J. Biol. Chem. 282(44): 32280-32287. doi:10.1074/jbc.M704150200. PMID:17848569.
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.44
, pp. 32280-32287
-
-
Saito, T.1
Jones, C.C.2
Huang, S.3
Czech, M.P.4
Pilch, P.F.5
-
87
-
-
45849105156
-
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
doi:10.1126/science.1157535. PMID:18497260
-
Sancak, Y., Peterson, T.R., Shaul, Y.D., Lindquist, R.A., Thoreen, C.C., Bar-Peled, L., and Sabatini, D.M. 2008. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science, 320(5882): 1496-1501. doi:10.1126/science.1157535. PMID:18497260.
-
(2008)
Science
, vol.320
, Issue.5882
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
Lindquist, R.A.4
Thoreen, C.C.5
Bar-Peled, L.6
Sabatini, D.M.7
-
88
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor independent pathway that regulates the cytoskeleton
-
doi:10.1016/j.cub.2004.06.054. PMID:15268862
-
Sarbassov, D.D., Ali, S.M., Kim, D.-H., Guertin, D.A., Latek, R.R., Erdjument-Bromage, H., et al. 2004. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor independent pathway that regulates the cytoskeleton. Curr. Biol. 14(14): 1296-1302. doi:10.1016/j.cub.2004.06.054. PMID:15268862.
-
(2004)
Curr. Biol.
, vol.14
, Issue.14
, pp. 1296-1302
-
-
Sarbassov, D.D.1
Ali, S.M.2
Kim D.-H. Guertin, D.A.3
Latek, R.R.4
Erdjument-Bromage, H.5
-
89
-
-
27544500981
-
Growing roles for the mTOR pathway
-
doi:10.1016/j.ceb.2005.09.009. PMID:16226444
-
Sarbassov, D.D., Ali, S.M., and Sabatini, D.M. 2005a. Growing roles for the mTOR pathway. Curr. Opin. Cell Biol. 17(6): 596-603. doi:10.1016/j.ceb.2005.09.009. PMID:16226444.
-
(2005)
Curr. Opin. Cell Biol.
, vol.17
, Issue.6
, pp. 596-603
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sabatini, D.M.3
-
90
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
doi:10.1126/science.1106148. PMID:15718470
-
Sarbassov, D.D., Guertin, D.A., Ali, S.M., and Sabatini, D.M. 2005b. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science, 307(5712): 1098-1101. doi:10.1126/science.1106148. PMID:15718470.
-
(2005)
Science
, vol.307
, Issue.5712
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
91
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
doi:10.1016/j.molcel.2006.03.029. PMID:16603397
-
Sarbassov, D.D., Ali, S.M., Sengupta, S., Sheen, J.H., Hsu, P.P., Bagley, A.F., et al. 2006. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol. Cell, 22(2): 159-168. doi:10.1016/j.molcel.2006.03.029. PMID:16603397.
-
(2006)
Mol. Cell
, vol.22
, Issue.2
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
-
92
-
-
35248820393
-
Rapamycinmediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation
-
doi:10.1016/j.metabol.2006.08.002. PMID:17142137
-
Sipula, I.J., Brown, N.F., and Perdomo, G. 2006. Rapamycinmediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation. Metabolism, 55(12): 1637-1644. doi:10.1016/j.metabol.2006.08.002. PMID:17142137.
-
(2006)
Metabolism
, vol.55
, Issue.12
, pp. 1637-1644
-
-
Sipula, I.J.1
Brown, N.F.2
Perdomo, G.3
-
93
-
-
21244480367
-
The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses
-
doi:10.1074/jbc.M414499200. PMID:15772076
-
Smith, E.M., Finn, S.G., Tee, A.R., Browne, G.J., and Proud, C.G. 2005. The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses. J. Biol. Chem. 280(19): 18717-18727. doi:10.1074/jbc.M414499200. PMID:15772076.
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.19
, pp. 18717-18727
-
-
Smith, E.M.1
Finn, S.G.2
Tee, A.R.3
Browne, G.J.4
Proud, C.G.5
-
94
-
-
46149098447
-
Phospholipase D1 is an effector of Rheb in the mTOR pathway
-
PMID:18550814
-
Sun, Y., Fang, Y., Yoon, M.S., Zhang, C., Roccio, M., Zwartkruis, F.J. 2008. Phospholipase D1 is an effector of Rheb in the mTOR pathway. Proc. Natl. Acad. Sci. U S A, 105(24): 8286-8291. PMID:18550814.
-
(2008)
Proc. Natl. Acad. Sci. U S A
, vol.105
, Issue.24
, pp. 8286-8291
-
-
Sun, Y.1
Fang, Y.2
Yoon, M.S.3
Zhang, C.4
Roccio, M.5
Zwartkruis, F.J.6
-
95
-
-
33244464562
-
Critical nodes in signalling pathways: insights into insulin action
-
PMID:16493415
-
Taniguchi, C.M., Emanuelli, B., and Kahn, C.R. 2006. Critical nodes in signalling pathways: insights into insulin action. Nature reviews 7(2): 85-96. PMID:16493415.
-
(2006)
Nature reviews
, vol.7
, Issue.2
, pp. 85-96
-
-
Taniguchi, C.M.1
Emanuelli, B.2
Kahn, C.R.3
-
96
-
-
65549145048
-
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
-
doi:10.1074/jbc.M900301200. PMID:19150980
-
Thoreen, C.C., Kang, S., Chang, J., Liu, Q., Zhang, J., Gao, Y., et al. 2009. An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J. Biol. Chem. 284(12): 8023-8032. doi:10.1074/jbc.M900301200. PMID:19150980.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.12
, pp. 8023-8032
-
-
Thoreen, C.C.1
Kang, S.2
Chang, J.3
Liu, Q.4
Zhang, J.5
Gao, Y.6
-
97
-
-
62849111751
-
Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin
-
doi:10.1128/MCB.00782-08. PMID:19114562
-
Toschi, A., Lee, E., Xu, L., Garcia, A., Gadir, N., and Foster, D.A. 2009. Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin. Mol. Cell. Biol. 29(6): 1411-1420. doi:10.1128/MCB.00782-08. PMID:19114562.
-
(2009)
Mol. Cell. Biol.
, vol.29
, Issue.6
, pp. 1411-1420
-
-
Toschi, A.1
Lee, E.2
Xu, L.3
Garcia, A.4
Gadir, N.5
Foster, D.A.6
-
98
-
-
0035851205
-
Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells
-
PMID:11498541
-
Tremblay, F., and Marette, A. 2001. Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells. J. Biol. Chem. 276(41): 38052-38060. PMID:11498541.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.41
, pp. 38052-38060
-
-
Tremblay, F.1
Marette, A.2
-
99
-
-
20844451550
-
Modulation of insulin action by dietary proteins and amino acids: role of the mammalian target of rapamycin nutrient sensing pathway
-
PMID:15930974
-
Tremblay, F., Jacques, H., and Marette, A. 2005. Modulation of insulin action by dietary proteins and amino acids: role of the mammalian target of rapamycin nutrient sensing pathway. Curr. Opin. Clin. Nutr. Metab. Care, 8(4): 457-462. PMID:15930974.
-
(2005)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.8
, Issue.4
, pp. 457-462
-
-
Tremblay, F.1
Jacques, H.2
Marette, A.3
-
100
-
-
35348832340
-
Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient-and obesity-induced insulin resistance
-
doi:10.1073/pnas.0706517104. PMID:17709744
-
Tremblay, F., Brule, S., Hee Um, S., Li, Y., Masuda, K., Roden, M., et al. 2007. Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient-and obesity-induced insulin resistance. Proc. Natl. Acad. Sci. U.S.A. 104(35): 14056-14061. doi:10.1073/pnas.0706517104. PMID:17709744.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, Issue.35
, pp. 14056-14061
-
-
Tremblay, F.1
Brule, S.2
Hee Um, S.3
Li, Y.4
Masuda, K.5
Roden, M.6
-
101
-
-
33644886769
-
Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTORmediated insulin receptor substrate 1 phosphorylation
-
doi:10.1128/MCB.26.1.63-76.2006. PMID:16354680
-
Tzatsos, A., and Kandror, K.V. 2006. Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTORmediated insulin receptor substrate 1 phosphorylation. Mol. Cell. Biol. 26(1): 63-76. doi:10.1128/MCB.26.1.63-76.2006. PMID:16354680.
-
(2006)
Mol. Cell. Biol.
, vol.26
, Issue.1
, pp. 63-76
-
-
Tzatsos, A.1
Kandror, K.V.2
-
102
-
-
4544220704
-
Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity
-
doi:10.1038/nature02866. PMID:15306821
-
Um, S.H., Frigerio, F., Watanabe, M., Picard, F., Joaquin, M., Sticker, M., et al. 2004. Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity. Nature, 431(7005): 200-205. doi:10.1038/nature02866. PMID:15306821.
-
(2004)
Nature
, vol.431
, Issue.7005
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
Sticker, M.6
-
103
-
-
33744505375
-
Nutrient overload insulin resistance, and ribosomal protein S6 kinase 1, S6K1
-
doi:10.1016/j.cmet.2006.05.003. PMID: 16753575
-
Um, S.H., D'Alessio, D., and Thomas, G. 2006. Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab. 3(6): 393-402. doi:10.1016/j.cmet.2006.05.003. PMID:16753575.
-
(2006)
Cell Metab
, vol.3
, Issue.6
, pp. 393-402
-
-
Um, S.H.1
D'Alessio, D.2
Thomas, G.3
-
104
-
-
0037022261
-
Dietary patterns and risk for type 2 diabetes mellitus in U.S. men
-
PMID:11827496
-
van Dam, R.M., Rimm, E.B., Willett, W.C., Stampfer, M.J., and Hu, F.B. 2002. Dietary patterns and risk for type 2 diabetes mellitus in U.S. men. Ann. Intern. Med. 136(3): 201-209. PMID:11827496.
-
(2002)
Ann. Intern. Med.
, vol.136
, Issue.3
, pp. 201-209
-
-
van Dam, R.M.1
Rimm, E.B.2
Willett, W.C.3
Stampfer, M.J.4
Hu, F.B.5
-
105
-
-
0032528917
-
Amino acid availability regulates p70 S6 kinase and multiple translation factors
-
PMID:9693128
-
Wang, X., Campbell, L.E., Miller, C.M., and Proud, C.G. 1998. Amino acid availability regulates p70 S6 kinase and multiple translation factors. Biochem. J. 334(1): 261-267. PMID:9693128.
-
(1998)
Biochem. J.
, vol.334
, Issue.1
, pp. 261-267
-
-
Wang, X.1
Campbell, L.E.2
Miller, C.M.3
Proud, C.G.4
-
106
-
-
48549107440
-
Differential effects of resistance and endurance exercise in the fed state on signaling molecule phosphorylation and protein synthesis in human muscle
-
Pt. 15: doi:10.1113/jphysiol.2008.153916. PMID:18556367
-
Wilkinson, S.B., Phillips, S.M., Atherton, P.J., Patel, R., Yarasheski, K.E., Tarnopolsky, M.A., and Rennie, M.J. 2008. Differential effects of resistance and endurance exercise in the fed state on signaling molecule phosphorylation and protein synthesis in human muscle. J. Physiol. 586(Pt. 15): 3701-3717. doi:10.1113/jphysiol.2008.153916. PMID:18556367.
-
(2008)
J. Physiol.
, vol.586
, pp. 3701-3717
-
-
Wilkinson, S.B.1
Phillips, S.M.2
Atherton, P.J.3
Patel, R.4
Yarasheski, K.E.5
Tarnopolsky, M.A.6
Rennie, M.J.7
-
107
-
-
39049179892
-
Effects of acute exercise and training on insulin action and sensitivity: focus on molecular mechanisms in muscle
-
doi:10.1042/bse0420031. PMID:17144878
-
Wojtaszewski, J.F., and Richter, E.A. 2006. Effects of acute exercise and training on insulin action and sensitivity: focus on molecular mechanisms in muscle. Essays Biochem. 42: 31-46. doi:10.1042/bse0420031. PMID:17144878.
-
(2006)
Essays Biochem
, vol.42
, pp. 31-46
-
-
Wojtaszewski, J.F.1
Richter, E.A.2
-
108
-
-
34547907805
-
Expanding mTOR signaling
-
doi:10.1038/cr.2007.64. PMID:17680028
-
Yang, Q., and Guan, K.L. 2007. Expanding mTOR signaling. Cell Res. 17(8): 666-681. doi:10.1038/cr.2007.64. PMID:17680028.
-
(2007)
Cell Res
, vol.17
, Issue.8
, pp. 666-681
-
-
Yang, Q.1
Guan, K.L.2
-
109
-
-
33645638721
-
Resistance training improves insulin signaling and action in skeletal muscle
-
doi:10.1097/00003677-200601000-00009. PMID:16394814
-
Yaspelkis, B.B., 3rd. 2006. Resistance training improves insulin signaling and action in skeletal muscle. Exerc. Sport Sci. Rev. 34(1): 42-46. doi:10.1097/00003677-200601000-00009. PMID:16394814.
-
(2006)
Exerc. Sport Sci. Rev.
, vol.34
, Issue.1
, pp. 42-46
-
-
Yaspelkis B.B., 3rd.1
-
110
-
-
27344447850
-
Elevated glucose activates protein synthesis in cultured cardiac myocytes
-
doi:10.1016/j.metabol.2005.05.010. PMID:16253633
-
Yeshao, W., Gu, J., Peng, X., Nairn, A.C., and Nadler, J.L. 2005. Elevated glucose activates protein synthesis in cultured cardiac myocytes. Metabolism, 54(11): 1453-1460. doi:10.1016/j.metabol.2005.05.010. PMID:16253633.
-
(2005)
Metabolism
, vol.54
, Issue.11
, pp. 1453-1460
-
-
Yeshao, W.1
Gu, J.2
Peng, X.3
Nairn, A.C.4
Nadler, J.L.5
-
111
-
-
47549087332
-
Signal transduction: Linking nutrients to growth
-
doi:10.1038/454287a. PMID:18633406
-
Zinzalla, V., and Hall, M.N. 2008. Signal transduction: Linking nutrients to growth. Nature, 454(7202): 287-288. doi:10.1038/454287a. PMID:18633406.
-
(2008)
Nature
, vol.454
, Issue.7202
, pp. 287-288
-
-
Zinzalla, V.1
Hall, M.N.2
|