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Volumn 296, Issue 4, 2009, Pages

Amino acid transceptors: Gate keepers of nutrient exchange and regulators of nutrient signaling

Author keywords

GCN2; Mammalian target of rapamycin; Receptors; SNAT2; Transporters

Indexed keywords

AMINO ACID RECEPTOR; AMINO ACID TRANSPORTER; ANTI NEUTRAL AMINO ACID TRANSPORTER; FUNGAL PROTEIN; GENERAL AMINO ACID PERMEASE; GLUTAMATE RECEPTOR; PERMEASE; PHOSPHATIDYLINOSITOL 3 KINASE; SSY1 PROTEIN; SYSTEM A AMINO ACID TRANSPORTER; TARGET OF RAPAMYCIN KINASE; UNCLASSIFIED DRUG; AMINO ACID;

EID: 65649152957     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.91002.2008     Document Type: Review
Times cited : (258)

References (107)
  • 1
    • 7644241534 scopus 로고    scopus 로고
    • Amino acid signaling in yeast: Casein kinase I and the Ssy5 endoprotease are key determinants of endoproteolytic activation of the membrane-bound Stp1 transcription factor
    • DOI 10.1128/MCB.24.22.9771-9785.2004
    • Abdel-Sater F, El Bakkoury M, Urrestarazu A, Vissers S, Andre B. Amino acid signaling in yeast: casein kinase I and the Ssy5 endoprotease are key determinants of endoproteolytic activation of the membrane-bound Stp1 transcription factor. Mol Cell Biol 24: 9771-9785, 2004. (Pubitemid 39458806)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.22 , pp. 9771-9785
    • Abdel-Sater, F.1    El Bakkoury, M.2    Urrestarazu, A.3    Vissers, S.4    Andre, B.5
  • 2
    • 0035169052 scopus 로고    scopus 로고
    • Possible linkage between glutamate transporter and mitogen-activated protein kinase cascade in cultured rat cortical astrocytes
    • DOI 10.1046/j.1471-4159.2001.00062.x
    • Abe K, Saito H. Possible linkage between glutamate transporter and mitogen-activated protein kinase cascade in cultured rat cortical astrocytes. J Neurochem 76: 217-223, 2001. (Pubitemid 32044385)
    • (2001) Journal of Neurochemistry , vol.76 , Issue.1 , pp. 217-223
    • Abe, K.1    Saito, H.2
  • 3
    • 0041353145 scopus 로고    scopus 로고
    • Structure and mechanism of the lactose permease of Escherichia coli
    • DOI 10.1126/science.1088196
    • Abramson J, Smirnova I, Kasho V, Verner G, Kaback HR, Iwata S. Structure and mechanism of the lactose permease of Escherichia coli. Science 301: 610-615, 2003. (Pubitemid 36927939)
    • (2003) Science , vol.301 , Issue.5633 , pp. 610-615
    • Abramson, J.1    Smirnova, I.2    Kasho, V.3    Verner, G.4    Kaback, H.R.5    Iwata, S.6
  • 4
    • 34447121352 scopus 로고    scopus 로고
    • Role of the transcription factor ATF4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids
    • Adams CM. Role of the transcription factor ATF4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids. J Biol Chem 282: 16744-16753, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 16744-16753
    • Adams, C.M.1
  • 5
    • 0020362670 scopus 로고
    • Plasma and muscle free amino acids in uremia: Influence of nutrition with amino acids
    • Alvestrand A, Fürst P, Bergström J. Plasma and muscle free amino acids in uremia: influence of nutrition with amino acids. Clin Nephrol 18: 297-303, 1982. (Pubitemid 13202007)
    • (1982) Clinical Nephrology , vol.18 , Issue.6 , pp. 297-305
    • Alvestrand, A.1    Furst, P.2    Bergstrom, J.3
  • 6
    • 0035993231 scopus 로고    scopus 로고
    • Excitatory amino acid transporters: Keeping up with glutamate
    • Amara SG, Fontana AC. Excitatory amino acid transporters: keeping up with glutamate. Neurochem Int 41: 313-318, 2002.
    • (2002) Neurochem Int , vol.41 , pp. 313-318
    • Amara, S.G.1    Fontana, A.C.2
  • 8
    • 33749173604 scopus 로고    scopus 로고
    • Identification of two cationic amino acid transporters required for nutritional signaling during mosquito reproduction
    • Attardo GM, Hansen IA, Shiao SH, Raikhel AS. Identification of two cationic amino acid transporters required for nutritional signaling during mosquito reproduction. J Exp Biol 209: 3071-3078, 2006.
    • (2006) J Exp Biol , vol.209 , pp. 3071-3078
    • Attardo, G.M.1    Hansen, I.A.2    Shiao, S.H.3    Raikhel, A.S.4
  • 10
    • 33846217457 scopus 로고    scopus 로고
    • Transporters for L-glutamate: An update on their molecular pharmacology and pathological involvement
    • Beart PM, O'shea RD. Transporters for L-glutamate: an update on their molecular pharmacology and pathological involvement. Br J Pharmacol 150: 5-17, 2007.
    • (2007) Br J Pharmacol , vol.150 , pp. 5-17
    • Beart, P.M.1    O'Shea, R.D.2
  • 11
    • 0001598487 scopus 로고    scopus 로고
    • Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2α kinase
    • DOI 10.1046/j.1432-1327.1999.00780.x
    • Berlanga JJ, Santoyo J, de Haro C. Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase. Eur J Biochem 265: 754-762, 1999. (Pubitemid 29489008)
    • (1999) European Journal of Biochemistry , vol.265 , Issue.2 , pp. 754-762
    • Berlanga, J.J.1    Santoyo, J.2    De Haro, C.3
  • 14
    • 0034916960 scopus 로고    scopus 로고
    • The acid-labile subunit (ALS) of the 150 kDa IGF-binding protein complex: An important but forgotten component of the circulating IGF system
    • DOI 10.1677/joe.0.1700063
    • Boisclair YR, Rhoads RP, Ueki I, Wang J, Ooi GT. The acid-labile subunit (ALS) of the 150 kDa IGF-binding protein complex: an important but forgotten component of the circulating IGF system. J Endocrinol 170: 63-70, 2001. (Pubitemid 32677567)
    • (2001) Journal of Endocrinology , vol.170 , Issue.1 , pp. 63-70
    • Boisclair, Y.R.1    Rhoads, R.P.2    Ueki, I.3    Wang, J.4    Ooi, G.T.5
  • 15
    • 1242295153 scopus 로고    scopus 로고
    • The SLC36 family: Proton-coupled transporters for the absorption of selected amino acids from extracellular and intracellular proteolysis
    • DOI 10.1007/s00424-003-1073-4, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Boll M, Daniel H, Gasnier B. The SLC36 family: proton-coupled transporters for the absorption of selected amino acids from extracellular and intracellular proteolysis. Pflügers Arch 447: 776-779, 2004. (Pubitemid 38241466)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 776-779
    • Boll, M.1    Daniel, H.2    Gasnier, B.3
  • 16
    • 25444457577 scopus 로고    scopus 로고
    • HVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase
    • Byfield MP, Murray JT, Backer JM. hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase. J Biol Chem 280: 33076-33082, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 33076-33082
    • Byfield, M.P.1    Murray, J.T.2    Backer, J.M.3
  • 17
    • 0025095302 scopus 로고
    • Role of amino-acid transport and counter-transport in nutrition and metabolism
    • Christensen HN. Role of amino-acid transport and counter-transport in nutrition and metabolism. Physiol Rev 70: 43-77, 1990.
    • (1990) Physiol Rev , vol.70 , pp. 43-77
    • Christensen, H.N.1
  • 18
    • 0037155888 scopus 로고    scopus 로고
    • Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a TOR-dependent manner
    • Christie GR, Hajduch E, Hundal HS, Proud CG, Taylor PM. Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a TOR-dependent manner. J Biol Chem 277: 9952-9953, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 9952-9953
    • Christie, G.R.1    Hajduch, E.2    Hundal, H.S.3    Proud, C.G.4    Taylor, P.M.5
  • 19
    • 0141733277 scopus 로고    scopus 로고
    • A nutrient sensor mechanism controls Drosophila growth
    • DOI 10.1016/S0092-8674(03)00713-X
    • Colombani J, Raisin S, Pantalacci S, Radimerski T, Montagne J, Leopold P. A nutrient sensor mechanism controls Drosophila growth. Cell 114: 739-749, 2003. (Pubitemid 37186768)
    • (2003) Cell , vol.114 , Issue.6 , pp. 739-749
    • Colombani, J.1    Raisin, S.2    Pantalacci, S.3    Radimerski, T.4    Montagne, J.5    Leopold, P.6
  • 20
    • 0030850943 scopus 로고    scopus 로고
    • The Sch9 protein kinase in the yeast Saccharomyces cerevisiae controls cAPK activity and is required for nitrogen activation of the fermentable-growth-medium-induced (FGM) pathway
    • Crauwels M, Donaton MC, Pernambuco MB, Winderickx J, de Winde JH, Thevelein JM. The Sch9 protein kinase in the yeast Saccharomyces cerevisiae controls cAPK activity and is required for nitrogen activation of the fermentable-growth-medium-induced (FGM) pathway. Microbiology 143: 2627-2637, 1997. (Pubitemid 27389948)
    • (1997) Microbiology , vol.143 , Issue.8 , pp. 2627-2637
    • Crauwels, M.1    Donaton, M.C.V.2    Pernambuco, M.B.3    Winderickx, J.4    De Winde, J.H.5    Thevelein, J.M.6
  • 21
    • 33646548305 scopus 로고    scopus 로고
    • The amino acid sensitive TOR pathway from yeast to mammals
    • DOI 10.1016/j.febslet.2006.04.068, PII S0014579306005084
    • Dann SG, Thomas G. The amino acid sensitive TOR pathway from yeast to mammals. FEBS Lett 580: 2821-2829, 2006. (Pubitemid 43729161)
    • (2006) FEBS Letters , vol.580 , Issue.12 , pp. 2821-2829
    • Dann, S.G.1    Thomas, G.2
  • 22
    • 0033807807 scopus 로고    scopus 로고
    • Transport rates of GABA transporters: Regulation by the N-terminal domain and syntaxin 1A
    • Deken SL, Beckman ML, Boos L, Quick MW. Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A. Nat Neurosci 3: 998-1003, 2000.
    • (2000) Nat Neurosci , vol.3 , pp. 998-1003
    • Deken, S.L.1    Beckman, M.L.2    Boos, L.3    Quick, M.W.4
  • 23
    • 0029927351 scopus 로고    scopus 로고
    • Amino acids induce expression of BAP2, a branched-chain amino acid permease gene in Saccharomyces cerevisiae
    • Didion T, Grausland M, Kielland-Brandt C, Andersen HA. Amino acids induce expression of BAP2, a branched-chain amino acid permease gene in Saccharomyces cerevisiae. J Bacteriol 178: 2025-2029, 1996. (Pubitemid 26110548)
    • (1996) Journal of Bacteriology , vol.178 , Issue.7 , pp. 2025-2029
    • Didion, T.1    Grauslund, M.2    Kielland-Brandt, M.C.3    Andersen, H.A.4
  • 24
    • 0031963197 scopus 로고    scopus 로고
    • The permease homologue Ssy1p controls the expression of amino acid and peptide transporter genes in Saccharomyces cerevisiae
    • DOI 10.1046/j.1365-2958.1998.00714.x
    • Didion T, Regenberg B, Jorgensen MU, KiellandBrandt MC, Andersen HA. The permease homologue Ssy1p controls the expression of amino acid and peptide transporter genes in saccharomyces cerevisiae. Mol Microbiol 27: 643-650, 1998. (Pubitemid 28045745)
    • (1998) Molecular Microbiology , vol.27 , Issue.3 , pp. 643-650
    • Didion, T.1    Regenberg, B.2    Jorgensen, M.U.3    Kielland-Brandt, M.C.4    Andersen, H.A.5
  • 25
    • 0242437856 scopus 로고    scopus 로고
    • The Gap1 general amino acid permease acts as an amino acid sensor for activation of protein kinase a targets in the yeast Saccharomyces cerevisiae
    • DOI 10.1046/j.1365-2958.2003.03732.x
    • Donaton MC, Holsbeeks I, Lagatie O, Van Zeebroeck G, Crauwels M, Winderickx J, Thevelein JM. The Gap1 general amino acid permease acts as an amino acid sensor for activation of protein kinase A targets in the yeast Saccharomyces cerevisiae. Mol Microbiol 50: 911-929, 2003. (Pubitemid 37372253)
    • (2003) Molecular Microbiology , vol.50 , Issue.3 , pp. 911-929
    • Donaton, M.C.V.1    Holsbeeks, I.2    Lagatie, O.3    Van Zeebroeck, G.4    Crauwels, M.5    Winderickx, J.6    Thevelein, J.M.7
  • 27
    • 0033501641 scopus 로고    scopus 로고
    • Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST
    • Duan S, Anderson CM, Stein BA, Swanson RA. Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST. J Neurosci 19: 10193-10200, 1999. (Pubitemid 30228026)
    • (1999) Journal of Neuroscience , vol.19 , Issue.23 , pp. 10193-10200
    • Duan, S.1    Anderson, C.M.2    Stein, B.A.3    Swanson, R.A.4
  • 30
    • 0034306249 scopus 로고    scopus 로고
    • Amino acid regulation of gene expression
    • Fafournoux P, Bruhat A, Jousse C. Amino acid regulation of gene expression. Biochem J 351: 1-12, 2000.
    • (2000) Biochem J , vol.351 , pp. 1-12
    • Fafournoux, P.1    Bruhat, A.2    Jousse, C.3
  • 32
    • 0030710958 scopus 로고    scopus 로고
    • Complementation of dominant suppression implicates CD98 in integrin activation
    • DOI 10.1038/36349
    • Fenczik CA, Sethi T, Ramos JW, Hughes PE, Ginsberg MH. Complementation of dominant suppression implicates CD98 in integrin activation. Nature 390: 81-85, 1997. (Pubitemid 27494760)
    • (1997) Nature , vol.390 , Issue.6655 , pp. 81-85
    • Fenczik, C.A.1    Sethi, T.2    Ramos, J.W.3    Hughes, P.E.4    Ginsberg, M.H.5
  • 33
    • 34147141941 scopus 로고    scopus 로고
    • A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling
    • DOI 10.1042/BJ20061881
    • Findlay GM, Yan L, Procter J, Mieulet V, Lamb RF. A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling. Biochem J 403: 13-20, 2007. (Pubitemid 46569862)
    • (2007) Biochemical Journal , vol.403 , Issue.1 , pp. 13-20
    • Findlay, G.M.1    Yan, L.2    Procter, J.3    Mieulet, V.4    Lamb, R.F.5
  • 34
    • 0025117461 scopus 로고
    • Substrate-dependent adaptive regulation and trans-inhibition of System A-mediated amino acid transport. Studies using rat hepatoma plasma membrane vesicles
    • Fong AD, Handlogten ME, Kilberg MS. Substrate-dependent adaptive regulation and trans-inhibition of System A-mediated amino acid transport. Studies using rat hepatoma plasma membrane vesicles. Biochim Biophys Acta 1022: 325-332, 1990.
    • (1990) Biochim Biophys Acta , vol.1022 , pp. 325-332
    • Fong, A.D.1    Handlogten, M.E.2    Kilberg, M.S.3
  • 35
    • 0035139183 scopus 로고    scopus 로고
    • Genetic and biochemical analysis of the yeast plasma membrane Ssy1p-Ptr3p-Ssy5p sensor of extracellular amino acids
    • DOI 10.1128/MCB.21.3.814-826.2001
    • Forsberg H, Ljungdahl PO. Genetic and biochemical analysis of the yeast plasma membrane Ssy1p-Ptr3p-Ssy5p sensor of extracellular amino acids. Mol Cell Biol 21: 814-826, 2001. (Pubitemid 32104730)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.3 , pp. 814-826
    • Forsberg, H.1    Ljungdahl, P.O.2
  • 36
    • 20144371132 scopus 로고    scopus 로고
    • Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: Role of glutamine and of cell shrinkage
    • DOI 10.1002/jcp.20272
    • Fumarola C, La Monica S, Guidotti GG. Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: role of glutamine and of cell shrinkage. J Cell Physiol 204: 155-165, 2005. (Pubitemid 40776818)
    • (2005) Journal of Cellular Physiology , vol.204 , Issue.1 , pp. 155-165
    • Fumarola, C.1    La Monica, S.2    Guidotti, G.G.3
  • 37
    • 33745838924 scopus 로고    scopus 로고
    • Amino acid starvation induces the SNAT2 neutral amino acid transporter by a mechanism that involves eukaryotic initiation factor 2α phosphorylation and cap-independent translation
    • DOI 10.1074/jbc.M600341200
    • Gaccioli F, Huang CC, Wang C, Bevilacqua E, Franchi-Gazzola R, Gazzola GC, Bussolati O, Snider MD, Hatzoglou M. Amino acid starvation induces the SNAT2 neutral amino acid transporter by a mechanism that involves eukaryotic initiation factor 2alpha phosphorylation and cap-independent translation. J Biol Chem 281: 17929-17940, 2006. (Pubitemid 44035592)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.26 , pp. 17929-17940
    • Gaccioli, F.1    Huang, C.C.2    Wang, C.3    Bevilacqua, E.4    Franchi-Gazzola, R.5    Gazzola, G.C.6    Bussolati, O.7    Snider, M.D.8    Hatzoglou, M.9
  • 38
    • 0036164788 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 increases activity and surface levels of the GLAST subtype of glutamate transporter
    • DOI 10.1016/S0197-0186(01)00106-1, PII S0197018601001061
    • Gamboa C, Ortega A. Insulin-like growth factor-1 increases activity and surface levels of the GLAST subtype of glutamate transporter. Neurochem Int 40: 397-403, 2002. (Pubitemid 34121984)
    • (2002) Neurochemistry International , vol.40 , Issue.5 , pp. 397-403
    • Gamboa, C.1    Ortega, A.2
  • 39
    • 0019829306 scopus 로고
    • Adaptive regulation of amino acid transport in cultured human fibroblasts. Sites and mechanism of action
    • Gazzola GC, Dall'Asta V, Guidotti GG. Adaptive regulation of amino acid transport in cultured human fibroblasts. Sites and mechanism of action. J Biol Chem 256: 3191-3198, 1981.
    • (1981) J Biol Chem , vol.256 , pp. 3191-3198
    • Gazzola, G.C.1    Dall'Asta, V.2    Guidotti, G.G.3
  • 40
    • 0035830702 scopus 로고    scopus 로고
    • The adaptive regulation of amino acid transport system a is associated to changes in ATA2 expression
    • DOI 10.1016/S0014-5793(01)02126-3, PII S0014579301021263
    • Gazzola RF, Sala R, Bussolati O, Visigalli R, Dall'Asta V, Ganapathy V, Gazzola GC. The adaptive regulation of amino acid transport system A is associated to changes in ATA2 expression. FEBS Lett 490: 11-14, 2001. (Pubitemid 32126635)
    • (2001) FEBS Letters , vol.490 , Issue.1-2 , pp. 11-14
    • Franchi Gazzola, R.1    Sala, R.2    Bussolati, O.3    Visigalli, R.4    Dall'Asta, V.5    Ganapathy, V.6    Gazzola, G.C.7
  • 41
    • 33645877686 scopus 로고    scopus 로고
    • High-affinity glutamate transporter GLAST/EAAT1 regulates cell surface expression of glutamine/neutral amino acid transporter ASCT2 in human fetal astrocytes
    • Gegelashvili M, Rodriguez-Kern A, Pirozhkova I, Zhang J, Sung L, Gegelashvili G. High-affinity glutamate transporter GLAST/EAAT1 regulates cell surface expression of glutamine/neutral amino acid transporter ASCT2 in human fetal astrocytes. Neurochem Int 48: 611-615, 2006.
    • (2006) Neurochem Int , vol.48 , pp. 611-615
    • Gegelashvili, M.1    Rodriguez-Kern, A.2    Pirozhkova, I.3    Zhang, J.4    Sung, L.5    Gegelashvili, G.6
  • 42
    • 34250730132 scopus 로고    scopus 로고
    • Glutamate transporter GLAST/EAAT1 directs cell surface expression of FXYD2/γ subunit of Na, K-ATPase in human fetal astrocytes
    • DOI 10.1016/j.neuint.2006.12.015, PII S0197018607000216
    • Gegelashvili M, Rodriguez-Kern A, Sung L, Shimamoto K, Gegelashvili G. Glutamate transporter GLAST/EAAT1 directs cell surface expression of FXYD2/gamma subunit of Na,K-ATPase in human fetal astrocytes. Neurochem Int 50: 916-920, 2007. (Pubitemid 46962814)
    • (2007) Neurochemistry International , vol.50 , Issue.7-8 , pp. 916-920
    • Gegelashvili, M.1    Rodriguez-Kern, A.2    Sung, L.3    Shimamoto, K.4    Gegelashvili, G.5
  • 43
    • 21044440310 scopus 로고    scopus 로고
    • PAT-related amino acid transporters regulate growth via a novel mechanism that does not require bulk transport of amino acids
    • DOI 10.1242/dev.01821
    • Goberdhan DC, Meredith D, Boyd CA, Wilson C. PAT-related amino acid transporters regulate growth via a novel mechanism that does not require bulk transport of amino acids. Development 132: 2365-2375, 2005. (Pubitemid 40872806)
    • (2005) Development , vol.132 , Issue.10 , pp. 2365-2375
    • Goberdhan, D.C.I.1    Meredith, D.2    Boyd, C.A.R.3    Wilson, C.4
  • 45
    • 0015392613 scopus 로고
    • Hormonal and adaptive control of amino acid transport in muscle
    • Guidotti GG. Hormonal and adaptive control of amino acid transport in muscle. Proc Nutr Soc 31: 179-184, 1972.
    • (1972) Proc Nutr Soc , vol.31 , pp. 179-184
    • Guidotti, G.G.1
  • 47
    • 0029942882 scopus 로고    scopus 로고
    • Association of hepatic system a amino acid transporter with the membrane-cytoskeletal proteins ankyrin and fodrin
    • DOI 10.1016/0005-2736(96)00046-6
    • Handlogten ME, Dudenhausen EE, Yang W, Kilberg MS. Association of hepatic system A amino acid transporter with the membranecytoskeletal proteins ankyrin and fodrin. Biochim Biophys Acta 1282: 107-114, 1996. (Pubitemid 26189204)
    • (1996) Biochimica et Biophysica Acta - Biomembranes , vol.1282 , Issue.1 , pp. 107-114
    • Handlogten, M.E.1    Dudenhausen, E.E.2    Yang, W.3    Kilberg, M.S.4
  • 48
    • 20144366618 scopus 로고    scopus 로고
    • Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito
    • Hansen IA, Attardo GM, Roy SG, Raikhel AS. Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito. J Biol Chem 280: 20565-20572, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 20565-20572
    • Hansen, I.A.1    Attardo, G.M.2    Roy, S.G.3    Raikhel, A.S.4
  • 50
    • 33846003862 scopus 로고    scopus 로고
    • Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2
    • DOI 10.1074/jbc.M606577200
    • Hatanaka T, Hatanaka Y, Setou M. Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2. J Biol Chem 281: 35922-35930, 2006. (Pubitemid 46041324)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.47 , pp. 35922-35930
    • Hatanaka, T.1    Hatanaka, Y.2    Setou, M.3
  • 51
    • 33745235142 scopus 로고    scopus 로고
    • TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth
    • DOI 10.1083/jcb.200511140
    • Hennig KM, Colombani J, Neufeld TP. TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth. J Cell Biol 173: 963-974, 2006. (Pubitemid 43920703)
    • (2006) Journal of Cell Biology , vol.173 , Issue.6 , pp. 963-974
    • Hennig, K.M.1    Colombani, J.2    Neufeld, T.P.3
  • 53
    • 0025762903 scopus 로고
    • Role of membrane transport in the regulation of skeletal muscle glutamine turnover
    • Hundal HS. Role of membrane transport in the regulation of skeletal muscle glutamine turnover. Clin Nutr 10 Suppl: 33-42, 1991.
    • (1991) Clin Nutr , Issue.10 SUPPL. , pp. 33-42
    • Hundal, H.S.1
  • 54
    • 0035340912 scopus 로고    scopus 로고
    • Subcellular localization and adaptive up-regulation of the System a (SAT2) amino acid transporter in skeletal-muscle cells and adipocytes
    • Hyde R, Christie GR, Litherland GJ, Hajduch E, Taylor PM, Hundal HS. Subcellular localization and adaptive up-regulation of the System A (SAT2) amino acid transporter in skeletal-muscle cells and adipocytes. Biochem J 355: 563-568, 2001. (Pubitemid 32434071)
    • (2001) Biochemical Journal , vol.355 , Issue.3 , pp. 563-568
    • Hyde, R.1    Christie, G.R.2    Litherland, G.J.3    Hajduch, E.4    Taylor, P.M.5    Hundal, H.S.6
  • 55
    • 34547124353 scopus 로고    scopus 로고
    • Distinct sensor pathways in the hierarchical control of SNAT2, a putative amino acid transceptor, by amino acid availability
    • DOI 10.1074/jbc.M611520200
    • Hyde R, Cwiklinski EL, MacAulay K, Taylor PM, Hundal HS. Distinct sensor pathways in the hierarchical control of SNAT2, a putative amino acid transceptor, by amino acid availability. J Biol Chem 282: 19788-19798, 2007. (Pubitemid 47100096)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.27 , pp. 19788-19798
    • Hyde, R.1    Cwiklinski, E.L.2    MacAulay, K.3    Taylor, P.M.4    Hundal, H.S.5
  • 56
    • 14644417747 scopus 로고    scopus 로고
    • Ceramide down-regulates System a amino acid transport and protein synthesis in rat skeletal muscle cells
    • DOI 10.1096/fj.04-2284fje
    • Hyde R, Hajduch E, Powell DJ, Taylor PM, Hundal HS. Ceramide down-regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells. FASEB J 19: 461-463, 2005. (Pubitemid 40316550)
    • (2005) FASEB Journal , vol.19 , Issue.3 , pp. 461-463
    • Hyde, R.1    Hajduch, E.2    Powell, D.J.3    Taylor, P.M.4    Hundal, H.S.5
  • 57
    • 0038682500 scopus 로고    scopus 로고
    • Amino acid transporters: Roles in amino acid sensing and signalling in animal cells
    • DOI 10.1042/BJ20030405
    • Hyde R, Taylor PM, Hundal HS. Amino acid transporters: roles in amino acid sensing and signalling in animal cells. Biochem J 373: 1-18, 2003. (Pubitemid 36819495)
    • (2003) Biochemical Journal , vol.373 , Issue.1 , pp. 1-18
    • Hyde, R.1    Taylor, P.M.2    Hundal, H.S.3
  • 58
    • 0036784803 scopus 로고    scopus 로고
    • Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons
    • Ingram SL, Prasad BM, Amara SG. Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons. Nat Neurosci 5: 971-978, 2002.
    • (2002) Nat Neurosci , vol.5 , pp. 971-978
    • Ingram, S.L.1    Prasad, B.M.2    Amara, S.G.3
  • 59
    • 51649104153 scopus 로고    scopus 로고
    • Leucine induces phosphorylation and activation of p70S6K in cortical neurons via the system L amino acid transporter
    • Ishizuka Y, Kakiya N, Nawa H, Takei N. Leucine induces phosphorylation and activation of p70S6K in cortical neurons via the system L amino acid transporter. J Neurochem 106: 934-942, 2008.
    • (2008) J Neurochem , vol.106 , pp. 934-942
    • Ishizuka, Y.1    Kakiya, N.2    Nawa, H.3    Takei, N.4
  • 61
    • 1242317710 scopus 로고    scopus 로고
    • The glutamate/neutral amino acid transporter family SLC1: Molecular, physiological and pharmacological aspects
    • DOI 10.1007/s00424-003-1146-4, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Kanai Y, Hediger MA. The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects. Pflügers Arch 447: 469-479, 2004. (Pubitemid 38241433)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 469-479
    • Kanai, Y.1    Hediger, M.A.2
  • 62
    • 49449116748 scopus 로고    scopus 로고
    • Symmetric transporters for asymmetric transport
    • Structural Biology
    • Karpowich NK, Wang Structural biology DN. Symmetric transporters for asymmetric transport. Science 321: 781-782, 2008.
    • (2008) Science , vol.321 , pp. 781-782
    • Karpowich, N.K.1    Wang, D.N.2
  • 63
    • 0021993469 scopus 로고
    • Adaptive regulation of neutral amino acid transport System a in rat H4 hepatoma cells
    • DOI 10.1002/jcp.1041220219
    • Kilberg MS, Han H, Barber EF, Chiles TC. Adaptive regulation of neutral amino acid transport System A in rat H4 hepatoma cells. J Cell Physiol 122: 290-298, 1985. (Pubitemid 15164132)
    • (1985) Journal of Cellular Physiology , vol.122 , Issue.2 , pp. 290-298
    • Kilberg, M.S.1    Han, H.-P.2    Barber, E.F.3    Chiles, T.C.4
  • 64
    • 23944431858 scopus 로고    scopus 로고
    • Nutritional control of gene expression: How mammalian cells respond to amino acid limitation
    • DOI 10.1146/annurev.nutr.24.012003.132145
    • Kilberg MS, Pan YX, Chen H, Leung-Pineda V. Nutritional control of gene expression: how mammalian cells respond to amino acid limitation. Annu Rev Nutr 25: 59-85, 2005. (Pubitemid 41208994)
    • (2005) Annual Review of Nutrition , vol.25 , pp. 59-85
    • Kilberg, M.S.1    Pan, Y.-X.2    Chen, H.3    Leung-Pineda, V.4
  • 65
    • 0032778041 scopus 로고    scopus 로고
    • Ssy1p and Ptr3p are plasma membrane components of a yeast system that senses extracellular amino acids
    • Klasson H, Fink GR, Ljungdahl PO. Ssy1p and Ptr3p are plasma membrane components of a yeast system that senses extracellular amino acids. Mol Cell Biol 19: 5405-5416, 1999. (Pubitemid 29339899)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.8 , pp. 5405-5416
    • Klasson, H.1    Fink, G.R.2    Ljungdahl, P.O.3
  • 66
    • 14744267948 scopus 로고    scopus 로고
    • Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle
    • Lang CH, Frost RA. Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle. J Cell Physiol 203: 144-155, 2005.
    • (2005) J Cell Physiol , vol.203 , pp. 144-155
    • Lang, C.H.1    Frost, R.A.2
  • 67
    • 0035795723 scopus 로고    scopus 로고
    • Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system a
    • DOI 10.1016/S0005-2736(01)00310-8, PII S0005273601003108
    • Ling R, Bridges CC, Sugawara M, Fujita T, Leibach FH, Prasad PD, Ganapathy V. Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A. Biochim Biophys Acta 1512: 15-21, 2001. (Pubitemid 32378780)
    • (2001) Biochimica et Biophysica Acta - Biomembranes , vol.1512 , Issue.1 , pp. 15-21
    • Ling, R.1    Bridges, C.C.2    Sugawara, M.3    Fujita, T.4    Leibach, F.H.5    Prasad, P.D.6    Ganapathy, V.7
  • 68
    • 37849030140 scopus 로고    scopus 로고
    • Activation of the SPS amino acid-sensing pathway in Saccharomyces cerevisiae correlates with the phosphorylation state of a sensor component, Ptr3
    • Liu Z, Thornton J, Spirek M, Butow RA. Activation of the SPS amino acid-sensing pathway in Saccharomyces cerevisiae correlates with the phosphorylation state of a sensor component, Ptr3. Mol Cell Biol 28: 551-563, 2008.
    • (2008) Mol Cell Biol , vol.28 , pp. 551-563
    • Liu, Z.1    Thornton, J.2    Spirek, M.3    Butow, R.A.4
  • 69
    • 4744369968 scopus 로고    scopus 로고
    • Glutamate-dependent transcriptional regulation of GLAST: Role of PKC
    • DOI 10.1111/j.1471-4159.2004.02706.x
    • Lopez-Bayghen E, Ortega A. Glutamate-dependent transcriptional regulation of GLAST: role of PKC. J Neurochem 91: 200-209, 2004. (Pubitemid 39314950)
    • (2004) Journal of Neurochemistry , vol.91 , Issue.1 , pp. 200-209
    • Lopez-Bayghen, E.1    Ortega, A.2
  • 70
    • 0030726759 scopus 로고    scopus 로고
    • Involvement of integrins and the cytoskeleton in modulation of skeletal muscle glycogen synthesis by changes in cell volume
    • Low SY, Rennie MJ, Taylor PM. Involvement of integrins and the cytoskeleton in modulation of skeletal muscle glycogen synthesis by changes in cell volume. FEBS Lett 417: 101-103, 1997.
    • (1997) FEBS Lett , vol.417 , pp. 101-103
    • Low, S.Y.1    Rennie, M.J.2    Taylor, P.M.3
  • 71
    • 0030771661 scopus 로고    scopus 로고
    • Signaling elements involved in amino acid transport responses to altered muscle cell volume
    • Low SY, Rennie MJ, Taylor PM. Signaling elements involved in amino acid transport responses to altered muscle cell volume. FASEB J 11: 1111-1117, 1997.
    • (1997) FASEB J , vol.11 , pp. 1111-1117
    • Low, S.Y.1    Rennie, M.J.2    Taylor, P.M.3
  • 72
    • 1242317638 scopus 로고    scopus 로고
    • Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family
    • DOI 10.1007/s00424-003-1117-9, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Mackenzie B, Erickson JD. Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family. Pflügers Arch 447: 784-795, 2004. (Pubitemid 38241468)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 784-795
    • Mackenzie, B.1    Erickson, J.D.2
  • 74
    • 50349087339 scopus 로고    scopus 로고
    • Insulin signaling and the general amino acid control response. Two distinct pathways to amino acid synthesis and uptake
    • Malmberg SE, Adams CM. Insulin signaling and the general amino acid control response. Two distinct pathways to amino acid synthesis and uptake. J Biol Chem 283: 19229-19234, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 19229-19234
    • Malmberg, S.E.1    Adams, C.M.2
  • 75
    • 0033569524 scopus 로고    scopus 로고
    • C-terminal interactions modulate the affinity of GLAST glutamate transporters in salamander retinal glial cells
    • DOI 10.1111/j.1469-7793.1999.00393.x
    • Marie H, Attwell D. C-terminal interactions modulate the affinity of GLAST glutamate transporters in salamander retinal glial cells. J Physiol 520: 393-397, 1999. (Pubitemid 29511903)
    • (1999) Journal of Physiology , vol.520 , Issue.2 , pp. 393-397
    • Marie, H.1    Attwell, D.2
  • 77
    • 0034176584 scopus 로고    scopus 로고
    • Minidiscs encodes a putative amino acid transporter subunit required non-autonomously for imaginal cell proliferation
    • DOI 10.1016/S0925-4773(99)00338-X, PII S092547739900338X
    • Martin JF, Hersperger E, Simcox A, Shearn A. minidiscs encodes a putative amino acid transporter subunit required non-autonomously for imaginal cell proliferation. Mech Dev 92: 155-167, 2000. (Pubitemid 30155911)
    • (2000) Mechanisms of Development , vol.92 , Issue.2 , pp. 155-167
    • Martin, J.F.1    Hersperger, E.2    Simcox, A.3    Shearn, A.4
  • 78
    • 0028971547 scopus 로고
    • Identification of the integrin alpha 3 beta 1 as a component of a partially purified A-system amino acid transporter from Ehrlich cell plasma membranes
    • McCormick JI, Johnstone RM. Identification of the integrin alpha 3 beta 1 as a component of a partially purified A-system amino acid transporter from Ehrlich cell plasma membranes. Biochem J 311: 743-751, 1995.
    • (1995) Biochem J , vol.311 , pp. 743-751
    • McCormick, J.I.1    Johnstone, R.M.2
  • 79
    • 0034257160 scopus 로고    scopus 로고
    • +-dependent glutamate transport activity
    • DOI 10.1016/S0197-0186(00)00018-8, PII S0197018600000188
    • Munir M, Correale DM, Robinson MB. Substrate-induced up-regulation of Na(+)-dependent glutamate transport activity. Neurochem Int 37: 147-162, 2000. (Pubitemid 30254147)
    • (2000) Neurochemistry International , vol.37 , Issue.2-3 , pp. 147-162
    • Munir, M.1    Correale, D.M.2    Robinson, M.B.3
  • 80
    • 34247273080 scopus 로고    scopus 로고
    • Mechanism and putative structure of B(0)-like neutral amino acid transporters
    • O'Mara M, Oakley A, Broer S. Mechanism and putative structure of B(0)-like neutral amino acid transporters. J Membr Biol 213: 111-118, 2006.
    • (2006) J Membr Biol , vol.213 , pp. 111-118
    • O'Mara, M.1    Oakley, A.2    Broer, S.3
  • 81
    • 33750456519 scopus 로고    scopus 로고
    • Global, in Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks
    • DOI 10.1016/j.cell.2006.09.026, PII S0092867406012748
    • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127: 635-648, 2006. (Pubitemid 44647421)
    • (2006) Cell , vol.127 , Issue.3 , pp. 635-648
    • Olsen, J.V.1    Blagoev, B.2    Gnad, F.3    Macek, B.4    Kumar, C.5    Mortensen, P.6    Mann, M.7
  • 82
    • 0031751209 scopus 로고    scopus 로고
    • Molecular biology of mammalian plasma membrane amino acid transporters
    • Palacin M, Estevez R, Bertran J, Zorzano A. Molecular biology of mammalian plasma membrane amino acid transporters. Physiol Rev 78: 969-1054, 1998. (Pubitemid 28491947)
    • (1998) Physiological Reviews , vol.78 , Issue.4 , pp. 969-1054
    • Palacin, M.1    Estevez, R.2    Bertran, J.3    Zorzano, A.4
  • 83
    • 1242295213 scopus 로고    scopus 로고
    • The ancillary proteins of HATs: SLC3 family of amino acid transporters
    • Palacin M, Kanai Y. The ancillary proteins of HATs: SLC3 family of amino acid transporters. Pflügers Arch 447: 490-494, 2004.
    • (2004) Pflügers Arch , vol.447 , pp. 490-494
    • Palacin, M.1    Kanai, Y.2
  • 84
    • 33646228377 scopus 로고    scopus 로고
    • Characterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System a transporter gene
    • Palii SS, Thiaville MM, Pan YX, Zhong C, Kilberg MS. Characterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System A transporter gene. Biochem J 395: 517-527, 2006.
    • (2006) Biochem J , vol.395 , pp. 517-527
    • Palii, S.S.1    Thiaville, M.M.2    Pan, Y.X.3    Zhong, C.4    Kilberg, M.S.5
  • 85
    • 39849093575 scopus 로고    scopus 로고
    • Hyper- and hyporesponsive mutant forms of the Saccharomyces cerevisiae Ssy1 amino acid sensor
    • Poulsen P, Gaber RF, Kielland-Brandt MC. Hyper- and hyporesponsive mutant forms of the Saccharomyces cerevisiae Ssy1 amino acid sensor. Mol Membr Biol 25: 164-176, 2008.
    • (2008) Mol Membr Biol , vol.25 , pp. 164-176
    • Poulsen, P.1    Gaber, R.F.2    Kielland-Brandt, M.C.3
  • 86
    • 33645063703 scopus 로고    scopus 로고
    • Mapping of an internal protease cleavage site in the Ssy5p component of the amino acid sensor of Saccharomyces cerevisiae and functional characterization of the resulting pro- And protease domains by gain-of-function genetics
    • Poulsen P, Lo LL, Kielland-Brandt MC. Mapping of an internal protease cleavage site in the Ssy5p component of the amino acid sensor of Saccharomyces cerevisiae and functional characterization of the resulting pro- and protease domains by gain-of-function genetics. Eukaryot Cell 5: 601-608, 2006.
    • (2006) Eukaryot Cell , vol.5 , pp. 601-608
    • Poulsen, P.1    Lo, L.L.2    Kielland-Brandt, M.C.3
  • 87
    • 0037117487 scopus 로고    scopus 로고
    • Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner
    • Quick MW. Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner. Proc Natl Acad Sci USA 99: 5686-5691, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5686-5691
    • Quick, M.W.1
  • 88
    • 33845544947 scopus 로고    scopus 로고
    • Signalling mechanisms underlying the release of glucagon-like peptide-1
    • Reimann F, Ward PS, Gribble FM. Signalling mechanisms underlying the release of glucagon-like peptide-1. Diabetes 55: S78-S85, 2006.
    • (2006) Diabetes , vol.55
    • Reimann, F.1    Ward, P.S.2    Gribble, F.M.3
  • 89
    • 37348999201 scopus 로고    scopus 로고
    • Lessons from "lower" organisms: What worms, flies, and zebrafish can teach us about human energy metabolism
    • Schlegel A, Stainier DY. Lessons from "lower" organisms: what worms, flies, and zebrafish can teach us about human energy metabolism. PLoS Genet 3: e199, 2007.
    • (2007) PLoS Genet , vol.3
    • Schlegel, A.1    Stainier, D.Y.2
  • 91
    • 44949086583 scopus 로고    scopus 로고
    • The mechanism of a neurotransmitter:sodium symporter-inward release of Na+ and substrate is triggered by substrate in a second binding site
    • Shi L, Quick M, Zhao Y, Weinstein H, Javitch JA. The mechanism of a neurotransmitter:sodium symporter-inward release of Na+ and substrate is triggered by substrate in a second binding site. Mol Cell 30: 667-677, 2008.
    • (2008) Mol Cell , vol.30 , pp. 667-677
    • Shi, L.1    Quick, M.2    Zhao, Y.3    Weinstein, H.4    Javitch, J.A.5
  • 92
    • 55249112985 scopus 로고    scopus 로고
    • Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex
    • Thiaville MM, Dudenhausen EE, Awad KS, Gjymishka A, Zhong C, Kilberg MS. Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex. Nucleic Acids Res 36: 5571-5580, 2008.
    • (2008) Nucleic Acids Res , vol.36 , pp. 5571-5580
    • Thiaville, M.M.1    Dudenhausen, E.E.2    Awad, K.S.3    Gjymishka, A.4    Zhong, C.5    Kilberg, M.S.6
  • 94
    • 57749119180 scopus 로고    scopus 로고
    • Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor
    • Van Zeebroeck G, Bonini BM, Versele M, Thevelein JM. Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Nat Chem Biol 5: 45-52, 2008.
    • (2008) Nat Chem Biol , vol.5 , pp. 45-52
    • Van Zeebroeck, G.1    Bonini, B.M.2    Versele, M.3    Thevelein, J.M.4
  • 95
    • 1342281232 scopus 로고    scopus 로고
    • CATs and HATs: The SLC7 family of amino acid transporters
    • DOI 10.1007/s00424-003-1086-z, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Verrey F, Closs EI, Wagner CA, Palacin M, Endou H, Kanai Y. CATs and HATs: the SLC7 family of amino acid transporters. Pflügers Arch 447: 532-542, 2004. (Pubitemid 38258215)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 532-542
    • Verrey, F.1    Closs, E.I.2    Wagner, C.A.3    Palacin, M.4    Endou, H.5    Kanai, Y.6
  • 96
    • 0016703172 scopus 로고
    • Influence of the postoperative state on the intracellular free amino acids in human muscle tissue
    • Vinnars E, Bergström J, Fürst P. Influence of the postoperative state on the intracellular free amino acids in human muscle tissue. Ann Surg 182: 665-671, 1975.
    • (1975) Ann Surg , vol.182 , pp. 665-671
    • Vinnars, E.1    Bergström, J.2    Fürst, P.3
  • 97
    • 33749431713 scopus 로고    scopus 로고
    • The mTOR pathway in the control of protein synthesis
    • Wang X, Proud CG. The mTOR pathway in the control of protein synthesis. Physiology (Bethesda) 21: 362-369, 2006.
    • (2006) Physiology (Bethesda) , vol.21 , pp. 362-369
    • Wang, X.1    Proud, C.G.2
  • 98
    • 32544446451 scopus 로고    scopus 로고
    • Coping with stress: EIF2 kinases and translational control
    • Wek RC, Jiang HY, Anthony TG. Coping with stress: eIF2 kinases and translational control. Biochem Soc Trans 34: 7-11, 2006.
    • (2006) Biochem Soc Trans , vol.34 , pp. 7-11
    • Wek, R.C.1    Jiang, H.Y.2    Anthony, T.G.3
  • 100
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • DOI 10.1016/j.cell.2006.01.016, PII S0092867406001085
    • Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 124: 471-484, 2006. (Pubitemid 43199434)
    • (2006) Cell , vol.124 , Issue.3 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 102
    • 24644470065 scopus 로고    scopus 로고
    • --dependent neurotransmitter transporters
    • DOI 10.1038/nature03978
    • Yamashita A, Singh SK, Kawate T, Jin Y, Gouaux E. Crystal structure of a bacterial homologue of Na+/Cl- dependent neurotransmitter transporters. Nature 437: 215-223, 2005. (Pubitemid 41294479)
    • (2005) Nature , vol.437 , Issue.7056 , pp. 215-223
    • Yamashita, A.1    Singh, S.K.2    Kawate, T.3    Jin, Y.4    Gouaux, E.5
  • 103
    • 0034312315 scopus 로고    scopus 로고
    • Regulation of cellular growth by the Drosophila target of rapamycin dTOR
    • DOI 10.1101/gad.835000
    • Zhang H, Stallock JP, Ng JC, Reinhard C, Neufeld TP. Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev 14: 2712-2724, 2000. (Pubitemid 32531198)
    • (2000) Genes and Development , vol.14 , Issue.21 , pp. 2712-2724
    • Zhang, H.1    Stallock, J.P.2    Ng, J.C.3    Reinhard, C.4    Neufeld, T.P.5
  • 105
    • 34047192789 scopus 로고    scopus 로고
    • The sodium-coupled neutral amino acid transporter SNAT2 mediates an anion leak conductance that is differentially inhibited by transported substrates
    • DOI 10.1529/biophysj.106.100776
    • Zhang Z, Grewer C. The sodium-coupled neutral amino acid transporter SNAT2 mediates an anion leak conductance that is differentially inhibited by transported substrates. Biophys J 92: 2621-2632, 2007. (Pubitemid 46536441)
    • (2007) Biophysical Journal , vol.92 , Issue.7 , pp. 2621-2632
    • Zhang, Z.1    Grewer, C.2
  • 106
    • 0033960571 scopus 로고    scopus 로고
    • Association of L-arginine transporters with fodrin: Implications for hypoxic inhibition of arginine uptake
    • Zharikov SI, Block ER. Association of L-arginine transporters with fodrin: implications for hypoxic inhibition of arginine uptake. Am J Physiol Lung Cell Mol Physiol 278: L111-L117, 2000.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.278
    • Zharikov, S.I.1    Block, E.R.2
  • 107
    • 34548684744 scopus 로고    scopus 로고
    • LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake
    • DOI 10.1126/science.1147614
    • Zhou Z, Zhen J, Karpowich NK, Goetz RM, Law CJ, Reith ME, Wang DN. LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. Science 317: 1390-1393, 2007. (Pubitemid 47417479)
    • (2007) Science , vol.317 , Issue.5843 , pp. 1390-1393
    • Zhou, Z.1    Zhen, J.2    Karpowich, N.K.3    Goetz, R.M.4    Law, C.J.5    Reith, M.E.A.6    Wang, D.-N.7


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