Elevated plasma free fatty acids decrease basal protein synthesis, but not the anabolic effect of leucine, in skeletal muscle

American Journal of Physiology - Endocrinology and Metabolism

Volumn 291, Issue 3, 2006, Pages

  Lang, Charles H ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Eukaryotic initiation factor 4E binding protein 1; Eukaryotic initiation factor 4G; Insulin like growth factor I; Leucine; Mammalian target of rapamycin; Tuberous sclerosis complex 2

Indexed keywords

FATTY ACID; HEPARIN; INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; INITIATION FACTOR 4G; INSULIN RECEPTOR SUBSTRATE 1; INTRALIPID; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN S6; S6 KINASE; S6 KINASE 1; SOMATOMEDIN C; TUBERIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; COMPLEX FORMATION; CONTROLLED STUDY; FATTY ACID BLOOD LEVEL; GLUCOSE TRANSPORT; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRANSLATION INITIATION;

ANIMALS; CARRIER PROTEINS; CONSCIOUSNESS; EUKARYOTIC INITIATION FACTOR-4E; EUKARYOTIC INITIATION FACTOR-4G; FAT EMULSIONS, INTRAVENOUS; FATTY ACIDS, NONESTERIFIED; HEPARIN; HYPERLIPIDEMIAS; INSULIN-LIKE GROWTH FACTOR I; LEUCINE; MALE; MUSCLE PROTEINS; MUSCLE, SKELETAL; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6; RIBOSOMAL PROTEIN S6 KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 33748452108     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00065.2006     Document Type: Article

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