-
1
-
-
0022443737
-
Familial adult motor neuron disease: amyotrophic lateral sclerosis
-
Familial adult motor neuron disease: amyotrophic lateral sclerosis. DW Mulder LT Kurland KP Offord CM Beard, Neurology 1986 36 511 517
-
(1986)
Neurology
, vol.36
, pp. 511-517
-
-
Mulder, D.W.1
Kurland, L.T.2
Offord, K.P.3
Beard, C.M.4
-
2
-
-
35248823549
-
Cognitive impairment in amyotrophic lateral sclerosis
-
DOI 10.1016/S1474-4422(07)70265-X, PII S147444220770265X
-
Cognitive impairment in amyotrophic lateral sclerosis. J Phukan NP Pender O Hardiman, Lancet Neurol 2007 6 994 1003 (Pubitemid 47562321)
-
(2007)
Lancet Neurology
, vol.6
, Issue.11
, pp. 994-1003
-
-
Phukan, J.1
Pender, N.P.2
Hardiman, O.3
-
3
-
-
0027055105
-
Adult onset motor neuron disease: Worldwide mortality, incidence and distribution since 1950
-
Adult onset motor neuron disease: worldwide mortality, incidence and distribution since 1950. AM Chancellor CP Warlow, J Neurol Neurosurg Psychiatry 1992 55 1106 1115
-
(1992)
J Neurol Neurosurg Psychiatry
, vol.55
, pp. 1106-1115
-
-
Chancellor, A.M.1
Warlow, C.P.2
-
4
-
-
0035936804
-
Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded
-
Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded. JP Julien, Cell 2001 104 581 591
-
(2001)
Cell
, vol.104
, pp. 581-591
-
-
Julien, J.P.1
-
5
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. DR Rosen T Siddique D Patterson DA Figlewicz P Sapp A Hentati D Donaldson J Goto JP O'Regan HX Deng Z Rhmani A Krizus D McKenna-Yasek A Cayabyab SM Gaston R Berger RE Tanzi JJ Haplerin B Herzfeldt R Van den Bergh WY Hung T Bird G Deng DW Mulder C Smyth NG Laing E Soriano MA Pericak-Vance J Haines GA Rouleau JS Gusella HR Horvitz RH Brown Jr, Nature 1993 362 59 62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
Rhmani, Z.11
Krizus, A.12
McKenna-Yasek, D.13
Cayabyab, A.14
Gaston, S.M.15
Berger, R.16
Tanzi, R.E.17
Haplerin, J.J.18
Herzfeldt, B.19
Van Den Bergh, R.20
Hung, W.Y.21
Bird, T.22
Deng, G.23
Mulder, D.W.24
Smyth, C.25
Laing, N.G.26
Soriano, E.27
Pericak-Vance, M.A.28
Haines, J.29
Rouleau, G.A.30
Gusella, J.S.31
Horvitz, H.R.32
Jr B. H, R.33
more..
-
6
-
-
33749056809
-
ALS: A disease of motor neurons and their nonneuronal neighbors
-
ALS: a disease of motor neurons and their nonneuronal neighbors. S Boillee C Vande Velde DW Cleveland, Neuron 2006 52 39 59
-
(2006)
Neuron
, vol.52
, pp. 39-59
-
-
Boillee, S.1
Velde, C.V.2
Cleveland, D.W.3
-
7
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS. LI Bruijn TM Miller DW Cleveland, Annu Rev Neurosci 2004 27 723 749
-
(2004)
Annu Rev Neurosci
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
8
-
-
0035516124
-
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
-
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. DW Cleveland JD Rothstein, Nat Rev Neurosci 2001 2 806 819
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
10
-
-
23144448320
-
Molecular and cellular pathways of neurodegeneration in motor neurone disease
-
Molecular and cellular pathways of neurodegeneration in motor neurone disease. PJ Shaw, J Neurol Neurosurg Psychiatry 2005 76 1046 1057
-
(2005)
J Neurol Neurosurg Psychiatry
, vol.76
, pp. 1046-1057
-
-
Shaw, P.J.1
-
11
-
-
23844538993
-
The pathobiology of amyotrophic lateral sclerosis: A proteinopathy?
-
The pathobiology of amyotrophic lateral sclerosis: a proteinopathy? MJ Strong S Kesavapany HC Pant, J Neuropathol Exp Neurol 2005 64 649 664
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 649-664
-
-
Strong, M.J.1
Kesavapany, S.2
Pant, H.C.3
-
12
-
-
0036257090
-
A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis
-
A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis. G Bensimon L Lacomblez JC Delumeau R Bejuit P Truffinet V Meininger, J Neurol 2002 249 609 615
-
(2002)
J Neurol
, vol.249
, pp. 609-615
-
-
Bensimon, G.1
Lacomblez, L.2
Delumeau, J.C.3
Bejuit, R.4
Truffinet, P.5
Meininger, V.6
-
13
-
-
0028097839
-
A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group
-
A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. G Bensimon L Lacomblez V Meininger, N Engl J Med 1994 330 585 591
-
(1994)
N Engl J Med
, vol.330
, pp. 585-591
-
-
Bensimon, G.1
Lacomblez, L.2
Meininger, V.3
-
14
-
-
0029753270
-
The pharmacology and mechanism of action of riluzole
-
The pharmacology and mechanism of action of riluzole. A Doble, Neurology 1996 47 S233 241
-
(1996)
Neurology
, vol.47
, pp. 233-241
-
-
Doble, A.1
-
15
-
-
0035991267
-
Long-term safety of riluzole in amyotrophic lateral sclerosis
-
DOI 10.1080/146608202317576507
-
Long-term safety of riluzole in amyotrophic lateral sclerosis. L Lacomblez G Bensimon PN Leigh C Debove R Bejuit P Truffinet V Meininger, Amyotroph Lateral Scler Other Motor Neuron Disord 2002 3 23 29 (Pubitemid 34705123)
-
(2002)
Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders
, vol.3
, Issue.1
, pp. 23-29
-
-
Lacomblez, L.1
Bensimon, G.2
Leigh, P.N.3
Debove, C.4
Bejuit, P.5
Truffinet, P.6
Meininger, V.7
-
16
-
-
0029977337
-
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II
-
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. L Lacomblez G Bensimon PN Leigh P Guillet V Meininger, Lancet 1996 347 1425 1431
-
(1996)
Lancet
, vol.347
, pp. 1425-1431
-
-
Lacomblez, L.1
Bensimon, G.2
Leigh, P.N.3
Guillet, P.4
Meininger, V.5
-
17
-
-
0029991177
-
Pathogenic mechanisms in familial amyotrophic lateral sclerosis due to mutation of Cu, Zn superoxide dismutase
-
Pathogenic mechanisms in familial amyotrophic lateral sclerosis due to mutation of Cu, Zn superoxide dismutase. ME Gurney FB Cutting P Zhai PK Andrus ED Hall, Pathol Biol (Paris) 1996 44 51 56
-
(1996)
Pathol Biol (Paris)
, vol.44
, pp. 51-56
-
-
Gurney, M.E.1
Cutting, F.B.2
Zhai, P.3
Andrus, P.K.4
Hall, E.D.5
-
18
-
-
0034624001
-
Copper- and zinc-containing superoxide dismutase can act as a superoxide reductase and a superoxide oxidase
-
Copper- and zinc-containing superoxide dismutase can act as a superoxide reductase and a superoxide oxidase. SI Liochev I Fridovich, J Biol Chem 2000 275 38482 38485
-
(2000)
J Biol Chem
, vol.275
, pp. 38482-38485
-
-
Liochev, S.I.1
Fridovich, I.2
-
19
-
-
0020374498
-
Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase
-
Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase. JA Tainer ED Getzoff KM Beem JS Richardson DC Richardson, J Mol Biol 1982 160 181 217
-
(1982)
J Mol Biol
, vol.160
, pp. 181-217
-
-
Tainer, J.A.1
Getzoff, E.D.2
Beem, K.M.3
Richardson, J.S.4
Richardson, D.C.5
-
21
-
-
0034789657
-
The geographical and ethnic distribution of the D90A CuZn-SOD mutation in the Russian Federation
-
The geographical and ethnic distribution of the D90A CuZn-SOD mutation in the Russian Federation. PM Andersen VA Spitsyn SV Makarov L Nilsson OI Kravchuk LS Bychkovskaya SL Marklund, Amyotroph Lateral Scler Other Motor Neuron Disord 2001 2 63 69
-
(2001)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.2
, pp. 63-69
-
-
Andersen, P.M.1
Spitsyn, V.A.2
Makarov, S.V.3
Nilsson, L.4
Kravchuk, O.I.5
Bychkovskaya, L.S.6
Marklund, S.L.7
-
23
-
-
9544236295
-
Autosomal recessive adult-onset amyotrophic lateral sclerosis associated with homozygosity for Asp90Ala CuZn-superoxide dismutase mutation. A clinical and genealogical study of 36 patients
-
Autosomal recessive adult-onset amyotrophic lateral sclerosis associated with homozygosity for Asp90Ala CuZn-superoxide dismutase mutation. A clinical and genealogical study of 36 patients. PM Andersen L Forsgren M Binzer P Nilsson V Ala-Hurula ML Keranen L Bergmark A Saarinen T Haltia I Tarvainen E Kinnunen B Udd SL Marklund, Brain 1996 119 Pt 4 1153 1172
-
(1996)
Brain
, vol.119
, Issue.PT 4
, pp. 1153-1172
-
-
Andersen, P.M.1
Forsgren, L.2
Binzer, M.3
Nilsson, P.4
Ala-Hurula, V.5
Keranen, M.L.6
Bergmark, L.7
Saarinen, A.8
Haltia, T.9
Tarvainen, I.10
Kinnunen, E.11
Udd, B.12
Marklund, S.L.13
-
24
-
-
0029010496
-
Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase
-
Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase. PM Andersen P Nilsson V Ala-Hurula ML Keranen I Tarvainen T Haltia L Nilsson M Binzer L Forsgren SL Marklund, Nat Genet 1995 10 61 66 10.1038/ng0595-61 7647793
-
(1995)
Nat Genet
, vol.10
, pp. 61-66
-
-
Andersen, P.M.1
Nilsson, P.2
Ala-Hurula, V.3
Keranen, M.L.4
Tarvainen, I.5
Haltia, T.6
Nilsson, L.7
Binzer, M.8
Forsgren, L.9
Marklund, S.L.10
-
25
-
-
0029584941
-
Superoxide dismutase in familial amyotrophic lateral sclerosis: Models for gain of function
-
Superoxide dismutase in familial amyotrophic lateral sclerosis: models for gain of function. RH Brown Jr, Curr Opin Neurobiol 1995 5 841 846
-
(1995)
Curr Opin Neurobiol
, vol.5
, pp. 841-846
-
-
Brown Jr., R.H.1
-
26
-
-
15844393658
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. AG Reaume JL Elliott EK Hoffman NW Kowall RJ Ferrante DF Siwek HM Wilcox DG Flood MF Beal RH Brown Jr RW Scott WD Snider, Nat Genet 1996 13 43 47
-
(1996)
Nat Genet
, vol.13
, pp. 43-47
-
-
Reaume, A.G.1
Elliott, J.L.2
Hoffman, E.K.3
Kowall, N.W.4
Ferrante, R.J.5
Siwek, D.F.6
Wilcox, H.M.7
Flood, D.G.8
Beal, M.F.9
Jr B. H, R.10
Scott, R.W.11
Snider, W.D.12
-
27
-
-
0027965073
-
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity
-
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. DR Borchelt MK Lee HS Slunt M Guarnieri ZS Xu PC Wong RH Brown Jr DL Price SS Sisodia DW Cleveland, Proc Natl Acad Sci USA 1994 91 8292 8296
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8292-8296
-
-
Borchelt, D.R.1
Lee, M.K.2
Slunt, H.S.3
Guarnieri, M.4
Xu, Z.S.5
Wong, P.C.6
Jr B. H, R.7
Price, D.L.8
Sisodia, S.S.9
Cleveland, D.W.10
-
28
-
-
0028940996
-
Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis
-
Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis. AC Bowling EE Barkowski D McKenna-Yasek P Sapp HR Horvitz MF Beal RH Brown Jr, J Neurochem 1995 64 2366 2369
-
(1995)
J Neurochem
, vol.64
, pp. 2366-2369
-
-
Bowling, A.C.1
Barkowski, E.E.2
McKenna-Yasek, D.3
Sapp, P.4
Horvitz, H.R.5
Beal, M.F.6
Jr B. H, R.7
-
29
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. LI Bruijn MK Houseweart S Kato KL Anderson SD Anderson E Ohama AG Reaume RW Scott DW Cleveland, Science 1998 281 1851 1854
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijn, L.I.1
Houseweart, M.K.2
Kato, S.3
Anderson, K.L.4
Anderson, S.D.5
Ohama, E.6
Reaume, A.G.7
Scott, R.W.8
Cleveland, D.W.9
-
30
-
-
0034520591
-
Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1
-
Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1. D Jaarsma ED Haasdijk JA Grashorn R Hawkins W van Duijn HW Verspaget J London JC Holstege, Neurobiol Dis 2000 7 623 643
-
(2000)
Neurobiol Dis
, vol.7
, pp. 623-643
-
-
Jaarsma, D.1
Haasdijk, E.D.2
Grashorn, J.A.3
Hawkins, R.4
Van Duijn, W.5
Verspaget, H.W.6
London, J.7
Holstege, J.C.8
-
31
-
-
38849182472
-
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model
-
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model. MM Harraz JJ Marden W Zhou Y Zhang A Williams VS Sharov K Nelson M Luo H Paulson C Schoneich JF Engelhardt, J Clin Invest 2008 118 659 670
-
(2008)
J Clin Invest
, vol.118
, pp. 659-670
-
-
Harraz, M.M.1
Marden, J.J.2
Zhou, W.3
Zhang, Y.4
Williams, A.5
Sharov, V.S.6
Nelson, K.7
Luo, M.8
Paulson, H.9
Schoneich, C.10
Engelhardt, J.F.11
-
32
-
-
33645798615
-
Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model
-
Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model. H Kikuchi G Almer S Yamashita C Guegan M Nagai Z Xu AA Sosunov GM McKhann 2nd S Przedborski, Proc Natl Acad Sci USA 2006 103 6025 6030
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6025-6030
-
-
Kikuchi, H.1
Almer, G.2
Yamashita, S.3
Guegan, C.4
Nagai, M.5
Xu, Z.6
Sosunov, A.A.7
McKhann II, G.M.8
Przedborski, S.9
-
33
-
-
44849124411
-
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
-
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1. H Nishitoh H Kadowaki A Nagai T Maruyama T Yokota H Fukutomi T Noguchi A Matsuzawa K Takeda H Ichijo, Genes Dev 2008 22 1451 1464
-
(2008)
Genes Dev
, vol.22
, pp. 1451-1464
-
-
Nishitoh, H.1
Kadowaki, H.2
Nagai, A.3
Maruyama, T.4
Yokota, T.5
Fukutomi, H.6
Noguchi, T.7
Matsuzawa, A.8
Takeda, K.9
Ichijo, H.10
-
34
-
-
0028933344
-
Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: A model of familial amyotrophic lateral sclerosis (FALS)
-
Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). MC Dal Canto ME Gurney, Brain Res 1995 676 25 40
-
(1995)
Brain Res
, vol.676
, pp. 25-40
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
35
-
-
0029991827
-
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: An immunohistochemical study
-
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study. SM Chou HS Wang K Komai, J Chem Neuroanat 1996 10 249 258
-
(1996)
J Chem Neuroanat
, vol.10
, pp. 249-258
-
-
Chou, S.M.1
Wang, H.S.2
Komai, K.3
-
36
-
-
0030797166
-
Pathological characterization of astrocytic hyaline inclusions in familial amyotrophic lateral sclerosis
-
Pathological characterization of astrocytic hyaline inclusions in familial amyotrophic lateral sclerosis. S Kato H Hayashi K Nakashima E Nanba M Kato A Hirano I Nakano K Asayama E Ohama, Am J Pathol 1997 151 611 620
-
(1997)
Am J Pathol
, vol.151
, pp. 611-620
-
-
Kato, S.1
Hayashi, H.2
Nakashima, K.3
Nanba, E.4
Kato, M.5
Hirano, A.6
Nakano, I.7
Asayama, K.8
Ohama, E.9
-
37
-
-
0029842923
-
Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis
-
Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis. N Shibata K Asayama A Hirano M Kobayashi, Dev Neurosci 1996 18 492 498
-
(1996)
Dev Neurosci
, vol.18
, pp. 492-498
-
-
Shibata, N.1
Asayama, K.2
Hirano, A.3
Kobayashi, M.4
-
38
-
-
33749070043
-
Insoluble mutant SOD1 is partly oligoubiquitinated in amyotrophic lateral sclerosis mice
-
Insoluble mutant SOD1 is partly oligoubiquitinated in amyotrophic lateral sclerosis mice. M Basso T Massignan G Samengo C Cheroni S De Biasi M Salmona C Bendotti V Bonetto, J Biol Chem 2006 281 33325 33335
-
(2006)
J Biol Chem
, vol.281
, pp. 33325-33335
-
-
Basso, M.1
Massignan, T.2
Samengo, G.3
Cheroni, C.4
De Biasi, S.5
Salmona, M.6
Bendotti, C.7
Bonetto, V.8
-
40
-
-
42949166848
-
Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: Prevention by mitochondrial-targeted antioxidants
-
Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants. P Cassina A Cassina M Pehar R Castellanos M Gandelman A de Leon KM Robinson RP Mason JS Beckman L Barbeito R Radi, J Neurosci 2008 28 4115 4122
-
(2008)
J Neurosci
, vol.28
, pp. 4115-4122
-
-
Cassina, P.1
Cassina, A.2
Pehar, M.3
Castellanos, R.4
Gandelman, M.5
De Leon, A.6
Robinson, K.M.7
Mason, R.P.8
Beckman, J.S.9
Barbeito, L.10
Radi, R.11
-
41
-
-
0141642203
-
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
-
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. AM Clement MD Nguyen EA Roberts ML Garcia S Boillee M Rule AP McMahon W Doucette D Siwek RJ Ferrante RH Brown Jr JP Julien LS Goldstein DW Cleveland, Science 2003 302 113 117
-
(2003)
Science
, vol.302
, pp. 113-117
-
-
Clement, A.M.1
Nguyen, M.D.2
Roberts, E.A.3
Garcia, M.L.4
Boillee, S.5
Rule, M.6
McMahon, A.P.7
Doucette, W.8
Siwek, D.9
Ferrante, R.J.10
Jr B. H, R.11
Julien, J.P.12
Goldstein, L.S.13
Cleveland, D.W.14
-
42
-
-
44649152645
-
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice
-
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. K Yamanaka S Boillee EA Roberts ML Garcia M McAlonis-Downes OR Mikse DW Cleveland LS Goldstein, Proc Natl Acad Sci USA 2008 105 7594 7599
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7594-7599
-
-
Yamanaka, K.1
Boillee, S.2
Roberts, E.A.3
Garcia, M.L.4
McAlonis-Downes, M.5
Mikse, O.R.6
Cleveland, D.W.7
Goldstein, L.S.8
-
43
-
-
38449113556
-
Genetics of sporadic amyotrophic lateral sclerosis
-
Genetics of sporadic amyotrophic lateral sclerosis. JC Schymick K Talbot BJ Traynor, Hum Mol Genet 2007 16 Spec No 2 R233 242
-
(2007)
Hum Mol Genet
, vol.16
, Issue.SPEC NO 2
, pp. 233-242
-
-
Schymick, J.C.1
Talbot, K.2
Traynor, B.J.3
-
44
-
-
37849043062
-
Genetics of familial amyotrophic lateral sclerosis
-
Genetics of familial amyotrophic lateral sclerosis. PN Valdmanis GA Rouleau, Neurology 2008 70 144 152
-
(2008)
Neurology
, vol.70
, pp. 144-152
-
-
Valdmanis, P.N.1
Rouleau, G.A.2
-
45
-
-
0028334717
-
Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35
-
DOI 10.1038/ng0794-425
-
Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35. A Hentati K Bejaoui MA Pericak-Vance F Hentati MC Speer WY Hung DA lewicz J Haines J Rimmler C Ben Hamida M Ben Hamida RH Brown Jr T Siddique, Nat Genet 1994 7 425 428 (Pubitemid 24204421)
-
(1994)
Nature Genetics
, vol.7
, Issue.3
, pp. 425-428
-
-
Hentati, A.1
Bejaoui, K.2
Pericak-Vance, M.A.3
Hentati, F.4
Speer, M.C.5
Hung, W.-Y.6
Figlewicz, D.A.7
Haines, J.8
Rimmler, J.9
Ben Hamida, C.10
Ben Hamida, M.11
Brown Jr., R.H.12
Siddique, T.13
-
46
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. S Hadano CK Hand H Osuga Y Yanagisawa A Otomo RS Devon N Miyamoto J Showguchi-Miyata Y Okada R Singaraja DA Figlewicz T Kwiatkowski BA Hosler T Sagie J Skaug J Nasir RH Brown Jr SW Scherer GA Rouleau MR Hayden JE Ikeda, Nat Genet 2001 29 166 173
-
(2001)
Nat Genet
, vol.29
, pp. 166-173
-
-
Hadano, S.1
Hand, C.K.2
Osuga, H.3
Yanagisawa, Y.4
Otomo, A.5
Devon, R.S.6
Miyamoto, N.7
Showguchi-Miyata, J.8
Okada, Y.9
Singaraja, R.10
Figlewicz, D.A.11
Kwiatkowski, T.12
Hosler, B.A.13
Sagie, T.14
Skaug, J.15
Nasir, J.16
Jr B. H, R.17
Scherer, S.W.18
Rouleau, G.A.19
Hayden, M.R.20
Ikeda, J.E.21
more..
-
47
-
-
0034785509
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Y Yang A Hentati HX Deng O Dabbagh T Sasaki M Hirano WY Hung K Ouahchi J Yan AC Azim N Cole G Gascon A Yagmour M Ben-Hamida M Pericak-Vance F Hentati T Siddique, Nat Genet 2001 29 160 165
-
(2001)
Nat Genet
, vol.29
, pp. 160-165
-
-
Yang, Y.1
Hentati, A.2
Deng, H.X.3
Dabbagh, O.4
Sasaki, T.5
Hirano, M.6
Hung, W.Y.7
Ouahchi, K.8
Yan, J.9
Azim, A.C.10
Cole, N.11
Gascon, G.12
Yagmour, A.13
Ben-Hamida, M.14
Pericak-Vance, M.15
Hentati, F.16
Siddique, T.17
-
48
-
-
0037234133
-
An ALS2 gene mutation causes hereditary spastic paraplegia in a Pakistani kindred
-
An ALS2 gene mutation causes hereditary spastic paraplegia in a Pakistani kindred. F Gros-Louis IA Meijer CK Hand MP Dube DL MacGregor MH Seni RS Devon MR Hayden F Andermann E Andermann GA Rouleau, Ann Neurol 2003 53 144 145
-
(2003)
Ann Neurol
, vol.53
, pp. 144-145
-
-
Gros-Louis, F.1
Meijer, I.A.2
Hand, C.K.3
Dube, M.P.4
MacGregor, D.L.5
Seni, M.H.6
Devon, R.S.7
Hayden, M.R.8
Andermann, F.9
Andermann, E.10
Rouleau, G.A.11
-
50
-
-
0025237394
-
Hereditary motor system diseases (chronic juvenile amyotrophic lateral sclerosis). Conditions combining a bilateral pyramidal syndrome with limb and bulbar amyotrophy
-
Hereditary motor system diseases (chronic juvenile amyotrophic lateral sclerosis). Conditions combining a bilateral pyramidal syndrome with limb and bulbar amyotrophy. M Ben Hamida F Hentati C Ben Hamida, Brain 1990 113 Pt 2 347 363
-
(1990)
Brain
, vol.113
, Issue.PT 2
, pp. 347-363
-
-
Ben Hamida, M.1
Hentati, F.2
Ben Hamida, C.3
-
51
-
-
38449092804
-
Alsin and the molecular pathways of amyotrophic lateral sclerosis
-
Alsin and the molecular pathways of amyotrophic lateral sclerosis. J Chandran J Ding H Cai, Mol Neurobiol 2007 36 224 231
-
(2007)
Mol Neurobiol
, vol.36
, pp. 224-231
-
-
Chandran, J.1
Ding, J.2
Cai, H.3
-
52
-
-
49249118746
-
TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander
-
TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander. GT Banks A Kuta AM Isaacs EM Fisher, Mamm Genome 2008 19 299 305
-
(2008)
Mamm Genome
, vol.19
, pp. 299-305
-
-
Banks, G.T.1
Kuta, A.2
Isaacs, A.M.3
Fisher, E.M.4
-
53
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. TJ Kwiatkowski Jr DA Bosco AL Leclerc E Tamrazian CR Vanderburg C Russ A Davis J Gilchrist EJ Kasarskis T Munsat P Valdmanis GA Rouleau BA Hosler P Cortelli PJ de Jong Y Yoshinaga JL Haines MA Pericak-Vance J Yan N Ticozzi T Siddique D McKenna-Yasek PC Sapp HR Horvitz JE Landers RH Brown Jr, Science 2009 323 1205 1208
-
(2009)
Science
, vol.323
, pp. 1205-1208
-
-
Jr K. J, T.1
Bosco, D.A.2
Leclerc, A.L.3
Tamrazian, E.4
Vanderburg, C.R.5
Russ, C.6
Davis, A.7
Gilchrist, J.8
Kasarskis, E.J.9
Munsat, T.10
Valdmanis, P.11
Rouleau, G.A.12
Hosler, B.A.13
Cortelli, P.14
De Jong, P.J.15
Yoshinaga, Y.16
Haines, J.L.17
Pericak-Vance, M.A.18
Yan, J.19
Ticozzi, N.20
Siddique, T.21
McKenna-Yasek, D.22
Sapp, P.C.23
Horvitz, H.R.24
Landers, J.E.25
Jr B. H, R.26
more..
-
54
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. C Vance B Rogelj T Hortobagyi KJ De Vos AL Nishimura J Sreedharan X Hu B Smith D Ruddy P Wright J Ganesalingam KL Williams V Tripathi S Al-Saraj A Al-Chalabi PN Leigh IP Blair G Nicholson J de Belleroche JM Gallo CC Miller CE Shaw, Science 2009 323 1208 1211
-
(2009)
Science
, vol.323
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobagyi, T.3
De Vos, K.J.4
Nishimura, A.L.5
Sreedharan, J.6
Hu, X.7
Smith, B.8
Ruddy, D.9
Wright, P.10
Ganesalingam, J.11
Williams, K.L.12
Tripathi, V.13
Al-Saraj, S.14
Al-Chalabi, A.15
Leigh, P.N.16
Blair, I.P.17
Nicholson, G.18
De Belleroche, J.19
Gallo, J.M.20
Miller, C.C.21
Shaw, C.E.22
more..
-
55
-
-
0042536473
-
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
-
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. M Arundine M Tymianski, Cell Calcium 2003 34 325 337
-
(2003)
Cell Calcium
, vol.34
, pp. 325-337
-
-
Arundine, M.1
Tymianski, M.2
-
56
-
-
0032709462
-
Calcium, glutamate, and amyotrophic lateral sclerosis: More evidence but no certainties
-
Calcium, glutamate, and amyotrophic lateral sclerosis: more evidence but no certainties. PJ Shaw, Ann Neurol 1999 46 803 805
-
(1999)
Ann Neurol
, vol.46
, pp. 803-805
-
-
Shaw, P.J.1
-
57
-
-
0027946813
-
The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis
-
The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis. ME Alexianu BK Ho AH Mohamed V La Bella RG Smith SH Appel, Ann Neurol 1994 36 846 858
-
(1994)
Ann Neurol
, vol.36
, pp. 846-858
-
-
Alexianu, M.E.1
Ho, B.K.2
Mohamed, A.H.3
La Bella, V.4
Smith, R.G.5
Appel, S.H.6
-
58
-
-
0025358573
-
Calbindin D-28k and parvalbumin in the rat nervous system
-
Calbindin D-28k and parvalbumin in the rat nervous system. MR Celio, Neuroscience 1990 35 375 475
-
(1990)
Neuroscience
, vol.35
, pp. 375-475
-
-
Celio, M.R.1
-
59
-
-
0027210116
-
Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease
-
Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease. P Ince N Stout P Shaw J Slade W Hunziker CW Heizmann KG Baimbridge, Neuropathol Appl Neurobiol 1993 19 291 299
-
(1993)
Neuropathol Appl Neurobiol
, vol.19
, pp. 291-299
-
-
Ince, P.1
Stout, N.2
Shaw, P.3
Slade, J.4
Hunziker, W.5
Heizmann, C.W.6
Baimbridge, K.G.7
-
60
-
-
0033569575
-
Calcium dynamics and buffering in motoneurones of the mouse spinal cord
-
Calcium dynamics and buffering in motoneurones of the mouse spinal cord. J Palecek MB Lips BU Keller, J Physiol 1999 520 Pt 2 485 502
-
(1999)
J Physiol
, vol.520
, Issue.PT 2
, pp. 485-502
-
-
Palecek, J.1
Lips, M.B.2
Keller, B.U.3
-
62
-
-
0025923461
-
Ca2+ permeability of KA-AMPA - Gated glutamate receptor channels depends on subunit composition
-
Ca2+ permeability of KA-AMPA - gated glutamate receptor channels depends on subunit composition. M Hollmann M Hartley S Heinemann, Science 1991 252 851 853
-
(1991)
Science
, vol.252
, pp. 851-853
-
-
Hollmann, M.1
Hartley, M.2
Heinemann, S.3
-
63
-
-
0025784548
-
Identification of a site in glutamate receptor subunits that controls calcium permeability
-
Identification of a site in glutamate receptor subunits that controls calcium permeability. RI Hume R Dingledine SF Heinemann, Science 1991 253 1028 1031
-
(1991)
Science
, vol.253
, pp. 1028-1031
-
-
Hume, R.I.1
Dingledine, R.2
Heinemann, S.F.3
-
64
-
-
0026543243
-
Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit
-
Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit. N Burnashev H Monyer PH Seeburg B Sakmann, Neuron 1992 8 189 198
-
(1992)
Neuron
, vol.8
, pp. 189-198
-
-
Burnashev, N.1
Monyer, H.2
Seeburg, P.H.3
Sakmann, B.4
-
65
-
-
0028941168
-
In vitro kainate injury to large, SMI-32(+) spinal neurons is Ca2+ dependent
-
In vitro kainate injury to large, SMI-32(+) spinal neurons is Ca2+ dependent. SG Carriedo HZ Yin R Lamberta JH Weiss, Neuroreport 1995 6 945 948
-
(1995)
Neuroreport
, vol.6
, pp. 945-948
-
-
Carriedo, S.G.1
Yin, H.Z.2
Lamberta, R.3
Weiss, J.H.4
-
66
-
-
0030015076
-
Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro
-
Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro. SG Carriedo HZ Yin JH Weiss, J Neurosci 1996 16 4069 4079
-
(1996)
J Neurosci
, vol.16
, pp. 4069-4079
-
-
Carriedo, S.G.1
Yin, H.Z.2
Weiss, J.H.3
-
68
-
-
0024454210
-
Kainic acid induces early and delayed degenerative neuronal changes in rat spinal cord
-
Kainic acid induces early and delayed degenerative neuronal changes in rat spinal cord. J Hugon JM Vallat PS Spencer MJ Leboutet D Barthe, Neurosci Lett 1989 104 258 262
-
(1989)
Neurosci Lett
, vol.104
, pp. 258-262
-
-
Hugon, J.1
Vallat, J.M.2
Spencer, P.S.3
Leboutet, M.J.4
Barthe, D.5
-
69
-
-
0029113872
-
Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity
-
Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity. JD Rothstein RW Kuncl, J Neurochem 1995 65 643 651
-
(1995)
J Neurochem
, vol.65
, pp. 643-651
-
-
Rothstein, J.D.1
Kuncl, R.W.2
-
70
-
-
0036713846
-
GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity
-
GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity. P Van Damme L Van Den Bosch E Van Houtte G Callewaert W Robberecht, J Neurophysiol 2002 88 1279 1287
-
(2002)
J Neurophysiol
, vol.88
, pp. 1279-1287
-
-
Van Damme, P.1
Van Den Bosch, L.2
Van Houtte, E.3
Callewaert, G.4
Robberecht, W.5
-
72
-
-
0030789347
-
Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors: A molecular determinant of selective vulnerability in amyotrophic lateral sclerosis
-
Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors: a molecular determinant of selective vulnerability in amyotrophic lateral sclerosis. TL Williams NC Day PG Ince RK Kamboj PJ Shaw, Ann Neurol 1997 42 200 207
-
(1997)
Ann Neurol
, vol.42
, pp. 200-207
-
-
Williams, T.L.1
Day, N.C.2
Ince, P.G.3
Kamboj, R.K.4
Shaw, P.J.5
-
73
-
-
2542498984
-
AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo
-
AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo. JC Corona R Tapia, J Neurochem 2004 89 988 997
-
(2004)
J Neurochem
, vol.89
, pp. 988-997
-
-
Corona, J.C.1
Tapia, R.2
-
74
-
-
34047131622
-
Ca2+-permeable AMPA receptors and intracellular Ca2+ determine motoneuron vulnerability in rat spinal cord in vivo
-
Ca2+-permeable AMPA receptors and intracellular Ca2+ determine motoneuron vulnerability in rat spinal cord in vivo. JC Corona R Tapia, Neuropharmacology 2007 52 1219 1228
-
(2007)
Neuropharmacology
, vol.52
, pp. 1219-1228
-
-
Corona, J.C.1
Tapia, R.2
-
75
-
-
0035001341
-
Glutamate uptake
-
Glutamate uptake. NC Danbolt, Prog Neurobiol 2001 65 1 105
-
(2001)
Prog Neurobiol
, vol.65
, pp. 1-105
-
-
Danbolt, N.C.1
-
76
-
-
0026597010
-
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
-
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. JD Rothstein LJ Martin RW Kuncl, N Engl J Med 1992 326 1464 1468
-
(1992)
N Engl J Med
, vol.326
, pp. 1464-1468
-
-
Rothstein, J.D.1
Martin, L.J.2
Kuncl, R.W.3
-
77
-
-
0028168346
-
[3H]D-aspartate binding sites in the normal human spinal cord and changes in motor neuron disease: A quantitative autoradiographic study
-
[3H]D-aspartate binding sites in the normal human spinal cord and changes in motor neuron disease: a quantitative autoradiographic study. PJ Shaw RM Chinnery PG Ince, Brain Res 1994 655 195 201
-
(1994)
Brain Res
, vol.655
, pp. 195-201
-
-
Shaw, P.J.1
Chinnery, R.M.2
Ince, P.G.3
-
78
-
-
0033938202
-
Excitatory amino acid transporter 1 and 2 immunoreactivity in the spinal cord in amyotrophic lateral sclerosis
-
Excitatory amino acid transporter 1 and 2 immunoreactivity in the spinal cord in amyotrophic lateral sclerosis. S Sasaki T Komori M Iwata, Acta Neuropathol 2000 100 138 144
-
(2000)
Acta Neuropathol
, vol.100
, pp. 138-144
-
-
Sasaki, S.1
Komori, T.2
Iwata, M.3
-
79
-
-
0023617392
-
Abnormal glutamate metabolism in amyotrophic lateral sclerosis
-
Abnormal glutamate metabolism in amyotrophic lateral sclerosis. A Plaitakis JT Caroscio, Ann Neurol 1987 22 575 579
-
(1987)
Ann Neurol
, vol.22
, pp. 575-579
-
-
Plaitakis, A.1
Caroscio, J.T.2
-
80
-
-
0025299819
-
Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis
-
Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis. JD Rothstein G Tsai RW Kuncl L Clawson DR Cornblath DB Drachman A Pestronk BL Stauch JT Coyle, Ann Neurol 1990 28 18 25
-
(1990)
Ann Neurol
, vol.28
, pp. 18-25
-
-
Rothstein, J.D.1
Tsai, G.2
Kuncl, R.W.3
Clawson, L.4
Cornblath, D.R.5
Drachman, D.B.6
Pestronk, A.7
Stauch, B.L.8
Coyle, J.T.9
-
81
-
-
0029067210
-
CSF and plasma amino acid levels in motor neuron disease: Elevation of CSF glutamate in a subset of patients
-
CSF and plasma amino acid levels in motor neuron disease: elevation of CSF glutamate in a subset of patients. PJ Shaw V Forrest PG Ince JP Richardson HJ Wastell, Neurodegeneration 1995 4 209 216
-
(1995)
Neurodegeneration
, vol.4
, pp. 209-216
-
-
Shaw, P.J.1
Forrest, V.2
Ince, P.G.3
Richardson, J.P.4
Wastell, H.J.5
-
82
-
-
0037081113
-
Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: A reappraisal using a new HPLC method with coulometric detection in a large cohort of patients
-
Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients. O Spreux-Varoquaux G Bensimon L Lacomblez F Salachas PF Pradat N Le Forestier A Marouan M Dib V Meininger, J Neurol Sci 2002 193 73 78
-
(2002)
J Neurol Sci
, vol.193
, pp. 73-78
-
-
Spreux-Varoquaux, O.1
Bensimon, G.2
Lacomblez, L.3
Salachas, F.4
Pradat, P.F.5
Le Forestier, N.6
Marouan, A.7
Dib, M.8
Meininger, V.9
-
83
-
-
60949096316
-
Chronic elevation of extracellular glutamate due to transport blockade is innocuous for spinal motoneurons in vivo
-
Chronic elevation of extracellular glutamate due to transport blockade is innocuous for spinal motoneurons in vivo. LB Tovar-y-Romo LD Santa-Cruz A Zepeda R Tapia, Neurochem Int 2009 54 186 191 10.1016/j.neuint.2008.09.015 19100799
-
(2009)
Neurochem Int
, vol.54
, pp. 186-191
-
-
Tovar-Y-Romo, L.B.1
Santa-Cruz, L.D.2
Zepeda, A.3
Tapia, R.4
-
84
-
-
33745270015
-
Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade
-
Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade. LB Tovar-y-Romo R Tapia, Exp Neurol 2006 199 281 290
-
(2006)
Exp Neurol
, vol.199
, pp. 281-290
-
-
Tovar-Y-Romo, L.B.1
Tapia, R.2
-
85
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. RJ Ferrante SE Browne LA Shinobu AC Bowling MJ Baik U MacGarvey NW Kowall RH Brown Jr MF Beal, J Neurochem 1997 69 2064 2074
-
(1997)
J Neurochem
, vol.69
, pp. 2064-2074
-
-
Ferrante, R.J.1
Browne, S.E.2
Shinobu, L.A.3
Bowling, A.C.4
Baik, M.J.5
MacGarvey, U.6
Kowall, N.W.7
Jr B. H, R.8
Beal, M.F.9
-
86
-
-
0030162231
-
Evidence for DNA damage in amyotrophic lateral sclerosis
-
Evidence for DNA damage in amyotrophic lateral sclerosis. PS Fitzmaurice IC Shaw HE Kleiner RT Miller TJ Monks SS Lau JD Mitchell PG Lynch, Muscle Nerve 1996 19 797 798
-
(1996)
Muscle Nerve
, vol.19
, pp. 797-798
-
-
Fitzmaurice, P.S.1
Shaw, I.C.2
Kleiner, H.E.3
Miller, R.T.4
Monks, T.J.5
Lau, S.S.6
Mitchell, J.D.7
Lynch, P.G.8
-
87
-
-
0029082389
-
Oxidative damage to protein in sporadic motor neuron disease spinal cord
-
Oxidative damage to protein in sporadic motor neuron disease spinal cord. PJ Shaw PG Ince G Falkous D Mantle, Ann Neurol 1995 38 691 695
-
(1995)
Ann Neurol
, vol.38
, pp. 691-695
-
-
Shaw, P.J.1
Ince, P.G.2
Falkous, G.3
Mantle, D.4
-
88
-
-
0028971936
-
Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis
-
Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis. K Abe LH Pan M Watanabe T Kato Y Itoyama, Neurosci Lett 1995 199 152 154
-
(1995)
Neurosci Lett
, vol.199
, pp. 152-154
-
-
Abe, K.1
Pan, L.H.2
Watanabe, M.3
Kato, T.4
Itoyama, Y.5
-
89
-
-
0030888919
-
Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis
-
Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis. K Abe LH Pan M Watanabe H Konno T Kato Y Itoyama, Neurol Res 1997 19 124 128
-
(1997)
Neurol Res
, vol.19
, pp. 124-128
-
-
Abe, K.1
Pan, L.H.2
Watanabe, M.3
Konno, H.4
Kato, T.5
Itoyama, Y.6
-
91
-
-
0035955478
-
Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients
-
Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients. N Shibata R Nagai K Uchida S Horiuchi S Yamada A Hirano M Kawaguchi T Yamamoto S Sasaki M Kobayashi, Brain Res 2001 917 97 104
-
(2001)
Brain Res
, vol.917
, pp. 97-104
-
-
Shibata, N.1
Nagai, R.2
Uchida, K.3
Horiuchi, S.4
Yamada, S.5
Hirano, A.6
Kawaguchi, M.7
Yamamoto, T.8
Sasaki, S.9
Kobayashi, M.10
-
92
-
-
0033807443
-
Increased oxidative damage to DNA in ALS patients
-
Increased oxidative damage to DNA in ALS patients. M Bogdanov RH Brown W Matson R Smart D Hayden H O'Donnell M Flint Beal M Cudkowicz, Free Radic Biol Med 2000 29 652 658
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 652-658
-
-
Bogdanov, M.1
Brown, R.H.2
Matson, W.3
Smart, R.4
Hayden, D.5
O'Donnell, H.6
Flint Beal, M.7
Cudkowicz, M.8
-
93
-
-
13244275028
-
Oxidative stress and metal content in blood and cerebrospinal fluid of amyotrophic lateral sclerosis patients with and without a Cu, Zn-superoxide dismutase mutation
-
Oxidative stress and metal content in blood and cerebrospinal fluid of amyotrophic lateral sclerosis patients with and without a Cu, Zn-superoxide dismutase mutation. Y Ihara K Nobukuni H Takata T Hayabara, Neurol Res 2005 27 105 108 10.1179/016164105X18430 15829169
-
(2005)
Neurol Res
, vol.27
, pp. 105-108
-
-
Ihara, Y.1
Nobukuni, K.2
Takata, H.3
Hayabara, T.4
-
94
-
-
0034283331
-
Blood oxidative stress in amyotrophic lateral sclerosis
-
Blood oxidative stress in amyotrophic lateral sclerosis. D Bonnefont-Rousselot L Lacomblez M Jaudon S Lepage F Salachas G Bensimon C Bizard V Doppler J Delattre V Meininger, J Neurol Sci 2000 178 57 62
-
(2000)
J Neurol Sci
, vol.178
, pp. 57-62
-
-
Bonnefont-Rousselot, D.1
Lacomblez, L.2
Jaudon, M.3
Lepage, S.4
Salachas, F.5
Bensimon, G.6
Bizard, C.7
Doppler, V.8
Delattre, J.9
Meininger, V.10
-
95
-
-
0030968429
-
Evaluation of antioxidants, protein, and lipid oxidation products in blood from sporadic amyotrophic lateral sclerosis patients
-
Evaluation of antioxidants, protein, and lipid oxidation products in blood from sporadic amyotrophic lateral sclerosis patients. PI Oteiza OD Uchitel F Carrasquedo AL Dubrovski JC Roma CG Fraga, Neurochem Res 1997 22 535 539
-
(1997)
Neurochem Res
, vol.22
, pp. 535-539
-
-
Oteiza, P.I.1
Uchitel, O.D.2
Carrasquedo, F.3
Dubrovski, A.L.4
Roma, J.C.5
Fraga, C.G.6
-
96
-
-
2442701519
-
Increased lipid peroxidation in sera of ALS patients: A potential biomarker of disease burden
-
Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden. EP Simpson YK Henry JS Henkel RG Smith SH Appel, Neurology 2004 62 1758 1765
-
(2004)
Neurology
, vol.62
, pp. 1758-1765
-
-
Simpson, E.P.1
Henry, Y.K.2
Henkel, J.S.3
Smith, R.G.4
Appel, S.H.5
-
97
-
-
0031722955
-
Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis
-
Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis. RG Smith YK Henry MP Mattson SH Appel, Ann Neurol 1998 44 696 699
-
(1998)
Ann Neurol
, vol.44
, pp. 696-699
-
-
Smith, R.G.1
Henry, Y.K.2
Mattson, M.P.3
Appel, S.H.4
-
98
-
-
0033009113
-
Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis
-
Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis. H Tohgi T Abe K Yamazaki T Murata E Ishizaki C Isobe, Ann Neurol 1999 46 129 131
-
(1999)
Ann Neurol
, vol.46
, pp. 129-131
-
-
Tohgi, H.1
Abe, T.2
Yamazaki, K.3
Murata, T.4
Ishizaki, E.5
Isobe, C.6
-
99
-
-
1842788079
-
Cerebrospinal fluid levels of free 3-nitrotyrosine are not elevated in the majority of patients with amyotrophic lateral sclerosis or Alzheimer's disease
-
Cerebrospinal fluid levels of free 3-nitrotyrosine are not elevated in the majority of patients with amyotrophic lateral sclerosis or Alzheimer's disease. H Ryberg AS Soderling P Davidsson K Blennow K Caidahl LI Persson, Neurochem Int 2004 45 57 62
-
(2004)
Neurochem Int
, vol.45
, pp. 57-62
-
-
Ryberg, H.1
Soderling, A.S.2
Davidsson, P.3
Blennow, K.4
Caidahl, K.5
Persson, L.I.6
-
100
-
-
0031784348
-
Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis. PK Andrus TJ Fleck ME Gurney ED Hall, J Neurochem 1998 71 2041 2048
-
(1998)
J Neurochem
, vol.71
, pp. 2041-2048
-
-
Andrus, P.K.1
Fleck, T.J.2
Gurney, M.E.3
Hall, E.D.4
-
101
-
-
18144398928
-
Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: Possible multifunctional role in the pathogenesis
-
Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis. F Casoni M Basso T Massignan E Gianazza C Cheroni M Salmona C Bendotti V Bonetto, J Biol Chem 2005 280 16295 16304
-
(2005)
J Biol Chem
, vol.280
, pp. 16295-16304
-
-
Casoni, F.1
Basso, M.2
Massignan, T.3
Gianazza, E.4
Cheroni, C.5
Salmona, M.6
Bendotti, C.7
Bonetto, V.8
-
102
-
-
0030767498
-
Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation
-
Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation. RJ Ferrante LA Shinobu JB Schulz RT Matthews CE Thomas NW Kowall ME Gurney MF Beal, Ann Neurol 1997 42 326 334
-
(1997)
Ann Neurol
, vol.42
, pp. 326-334
-
-
Ferrante, R.J.1
Shinobu, L.A.2
Schulz, J.B.3
Matthews, R.T.4
Thomas, C.E.5
Kowall, N.W.6
Gurney, M.E.7
Beal, M.F.8
-
103
-
-
0031768025
-
Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis. R Liu JS Althaus BR Ellerbrock DA Becker ME Gurney, Ann Neurol 1998 44 763 770
-
(1998)
Ann Neurol
, vol.44
, pp. 763-770
-
-
Liu, R.1
Althaus, J.S.2
Ellerbrock, B.R.3
Becker, D.A.4
Gurney, M.E.5
-
104
-
-
22544448129
-
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice - A model of familial amyotrophic lateral sclerosis
-
DOI 10.1016/j.freeradbiomed.2005.03.030, PII S0891584905001875
-
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice - a model of familial amyotrophic lateral sclerosis. HF Poon K Hensley V Thongboonkerd ML Merchant BC Lynn WM Pierce JB Klein V Calabrese DA Butterfield, Free Radic Biol Med 2005 39 453 462 (Pubitemid 41021644)
-
(2005)
Free Radical Biology and Medicine
, vol.39
, Issue.4
, pp. 453-462
-
-
Poon, H.F.1
Hensley, K.2
Thongboonkerd, V.3
Merchant, M.L.4
Lynn, B.C.5
Pierce, W.M.6
Klein, J.B.7
Calabrese, V.8
Butterfield, D.A.9
-
105
-
-
0034004476
-
AMPA exposures induce mitochondrial Ca(2+) overload and ROS generation in spinal motor neurons in vitro
-
AMPA exposures induce mitochondrial Ca(2+) overload and ROS generation in spinal motor neurons in vitro. SG Carriedo SL Sensi HZ Yin JH Weiss, J Neurosci 2000 20 240 250
-
(2000)
J Neurosci
, vol.20
, pp. 240-250
-
-
Carriedo, S.G.1
Sensi, S.L.2
Yin, H.Z.3
Weiss, J.H.4
-
107
-
-
0032926368
-
Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis
-
Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis. A Al-Chalabi PM Andersen P Nilsson B Chioza JL Andersson C Russ CE Shaw JF Powell PN Leigh, Hum Mol Genet 1999 8 157 164
-
(1999)
Hum Mol Genet
, vol.8
, pp. 157-164
-
-
Al-Chalabi, A.1
Andersen, P.M.2
Nilsson, P.3
Chioza, B.4
Andersson, J.L.5
Russ, C.6
Shaw, C.E.7
Powell, J.F.8
Leigh, P.N.9
-
108
-
-
0028001606
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. DA Figlewicz A Krizus MG Martinoli V Meininger M Dib GA Rouleau JP Julien, Hum Mol Genet 1994 3 1757 1761
-
(1994)
Hum Mol Genet
, vol.3
, pp. 1757-1761
-
-
Figlewicz, D.A.1
Krizus, A.2
Martinoli, M.G.3
Meininger, V.4
Dib, M.5
Rouleau, G.A.6
Julien, J.P.7
-
109
-
-
0032427646
-
Novel insertion in the KSP region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS)
-
Novel insertion in the KSP region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS). J Tomkins P Usher JY Slade PG Ince A Curtis K Bushby PJ Shaw, Neuroreport 1998 9 3967 3970
-
(1998)
Neuroreport
, vol.9
, pp. 3967-3970
-
-
Tomkins, J.1
Usher, P.2
Slade, J.Y.3
Ince, P.G.4
Curtis, A.5
Bushby, K.6
Shaw, P.J.7
-
110
-
-
0027465098
-
Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
-
Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. F Cote JF Collard JP Julien, Cell 1993 73 35 46
-
(1993)
Cell
, vol.73
, pp. 35-46
-
-
Cote, F.1
Collard, J.F.2
Julien, J.P.3
-
111
-
-
0027410516
-
Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
-
Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Z Xu LC Cork JW Griffin DW Cleveland, Cell 1993 73 23 33
-
(1993)
Cell
, vol.73
, pp. 23-33
-
-
Xu, Z.1
Cork, L.C.2
Griffin, J.W.3
Cleveland, D.W.4
-
112
-
-
0017669602
-
Mouse spinal cord in cell culture. I. Morphology and intrinsic neuronal electrophysiologic properties
-
Mouse spinal cord in cell culture. I. Morphology and intrinsic neuronal electrophysiologic properties. BR Ransom E Neale M Henkart PN Bullock PG Nelson, J Neurophysiol 1977 40 1132 1150
-
(1977)
J Neurophysiol
, vol.40
, pp. 1132-1150
-
-
Ransom, B.R.1
Neale, E.2
Henkart, M.3
Bullock, P.N.4
Nelson, P.G.5
-
113
-
-
0019794038
-
Separation of cell types from embryonic chicken and 333062 rat spinal cord: Characterization of motoneuron-enriched fractions
-
7264717
-
Separation of cell types from embryonic chicken and rat spinal cord: characterization of motoneuron-enriched fractions. RI Schnaar AE Schaffner, J Neurosci 1981 1 204 217 7264717
-
(1981)
J Neurosci
, vol.1
, pp. 204-217
-
-
Schnaar, R.I.1
Schaffner, A.E.2
-
114
-
-
0026630523
-
Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor
-
Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor. W Camu CE Henderson, J Neurosci Methods 1992 44 59 70
-
(1992)
J Neurosci Methods
, vol.44
, pp. 59-70
-
-
Camu, W.1
Henderson, C.E.2
-
115
-
-
0021522805
-
Motoneurons purified by cell sorting respond to two distinct activities in myotube-conditioned medium
-
Motoneurons purified by cell sorting respond to two distinct activities in myotube-conditioned medium. AL Calof LF Reichardt, Dev Biol 1984 106 194 210
-
(1984)
Dev Biol
, vol.106
, pp. 194-210
-
-
Calof, A.L.1
Reichardt, L.F.2
-
116
-
-
0037047320
-
Directed differentiation of embryonic stem cells into motor neurons
-
Directed differentiation of embryonic stem cells into motor neurons. H Wichterle I Lieberam JA Porter TM Jessell, Cell 2002 110 385 397
-
(2002)
Cell
, vol.110
, pp. 385-397
-
-
Wichterle, H.1
Lieberam, I.2
Porter, J.A.3
Jessell, T.M.4
-
117
-
-
0345269737
-
Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons
-
Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons. SD Rao HZ Yin JH Weiss, J Neurosci 2003 23 2627 2633
-
(2003)
J Neurosci
, vol.23
, pp. 2627-2633
-
-
Rao, S.D.1
Yin, H.Z.2
Weiss, J.H.3
-
118
-
-
34247473080
-
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
-
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. FP Di Giorgio MA Carrasco MC Siao T Maniatis K Eggan, Nat Neurosci 2007 10 608 614
-
(2007)
Nat Neurosci
, vol.10
, pp. 608-614
-
-
Di Giorgio, F.P.1
Carrasco, M.A.2
Siao, M.C.3
Maniatis, T.4
Eggan, K.5
-
119
-
-
34247475338
-
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
-
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. M Nagai DB Re T Nagata A Chalazonitis TM Jessell H Wichterle S Przedborski, Nat Neurosci 2007 10 615 622
-
(2007)
Nat Neurosci
, vol.10
, pp. 615-622
-
-
Nagai, M.1
Re, D.B.2
Nagata, T.3
Chalazonitis, A.4
Jessell, T.M.5
Wichterle, H.6
Przedborski, S.7
-
120
-
-
34548233140
-
Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia
-
Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia. Q Xiao W Zhao DR Beers AA Yen W Xie JS Henkel SH Appel, J Neurochem 2007 102 2008 2019
-
(2007)
J Neurochem
, vol.102
, pp. 2008-2019
-
-
Xiao, Q.1
Zhao, W.2
Beers, D.R.3
Yen, A.A.4
Xie, W.5
Henkel, J.S.6
Appel, S.H.7
-
121
-
-
0026465350
-
Neuroblastoma × spinal cord (NSC) hybrid cell lines resemble developing motor neurons
-
Neuroblastoma × spinal cord (NSC) hybrid cell lines resemble developing motor neurons. NR Cashman HD Durham JK Blusztajn K Oda T Tabira IT Shaw S Dahrouge JP Antel, Dev Dyn 1992 194 209 221
-
(1992)
Dev Dyn
, vol.194
, pp. 209-221
-
-
Cashman, N.R.1
Durham, H.D.2
Blusztajn, J.K.3
Oda, K.4
Tabira, T.5
Shaw, I.T.6
Dahrouge, S.7
Antel, J.P.8
-
122
-
-
43149109289
-
Establishment of a cell model of ALS disease: Golgi apparatus disruption occurs independently from apoptosis
-
Establishment of a cell model of ALS disease: Golgi apparatus disruption occurs independently from apoptosis. C Gomes AS Palma R Almeida M Regalla LF McCluskey JQ Trojanowski J Costa, Biotechnol Lett 2008 30 603 610
-
(2008)
Biotechnol Lett
, vol.30
, pp. 603-610
-
-
Gomes, C.1
Palma, A.S.2
Almeida, R.3
Regalla, M.4
McCluskey, L.F.5
Trojanowski, J.Q.6
Costa, J.7
-
123
-
-
33746215801
-
Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1
-
Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1. A Raimondi A Mangolini M Rizzardini S Tartari S Massari C Bendotti M Francolini N Borgese L Cantoni G Pietrini, Eur J Neurosci 2006 24 387 399
-
(2006)
Eur J Neurosci
, vol.24
, pp. 387-399
-
-
Raimondi, A.1
Mangolini, A.2
Rizzardini, M.3
Tartari, S.4
Massari, S.5
Bendotti, C.6
Francolini, M.7
Borgese, N.8
Cantoni, L.9
Pietrini, G.10
-
124
-
-
33749563294
-
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1
-
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1. JD Atkin MA Farg BJ Turner D Tomas JA Lysaght J Nunan A Rembach P Nagley PM Beart SS Cheema MK Horne, J Biol Chem 2006 281 30152 30165
-
(2006)
J Biol Chem
, vol.281
, pp. 30152-30165
-
-
Atkin, J.D.1
Farg, M.A.2
Turner, B.J.3
Tomas, D.4
Lysaght, J.A.5
Nunan, J.6
Rembach, A.7
Nagley, P.8
Beart, P.M.9
Cheema, S.S.10
Horne, M.K.11
-
125
-
-
38149115471
-
Cysteine 111 affects aggregation and cytotoxicity of mutant Cu, Zn-superoxide dismutase associated with familial amyotrophic lateral sclerosis
-
Cysteine 111 affects aggregation and cytotoxicity of mutant Cu, Zn-superoxide dismutase associated with familial amyotrophic lateral sclerosis. M Cozzolino I Amori MG Pesaresi A Ferri M Nencini MT Carri, J Biol Chem 2008 283 866 874
-
(2008)
J Biol Chem
, vol.283
, pp. 866-874
-
-
Cozzolino, M.1
Amori, I.2
Pesaresi, M.G.3
Ferri, A.4
Nencini, M.5
Carri, M.T.6
-
126
-
-
17844364182
-
Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells
-
Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells. M Rizzardini A Mangolini M Lupi P Ubezio C Bendotti L Cantoni, J Neurol Sci 2005 232 95 103
-
(2005)
J Neurol Sci
, vol.232
, pp. 95-103
-
-
Rizzardini, M.1
Mangolini, A.2
Lupi, M.3
Ubezio, P.4
Bendotti, C.5
Cantoni, L.6
-
127
-
-
0037541152
-
The MYC oncogene as a cancer drug target
-
The MYC oncogene as a cancer drug target. H Hermeking, Curr Cancer Drug Targets 2003 3 163 175
-
(2003)
Curr Cancer Drug Targets
, vol.3
, pp. 163-175
-
-
Hermeking, H.1
-
128
-
-
0024391672
-
Ventral and dorsal horn acetylcholinesterase neurons are maintained in organotypic cultures of postnatal rat spinal cord explants
-
Ventral and dorsal horn acetylcholinesterase neurons are maintained in organotypic cultures of postnatal rat spinal cord explants. J Delfs J Friend S Ishimoto D Saroff, Brain Res 1989 488 31 42
-
(1989)
Brain Res
, vol.488
, pp. 31-42
-
-
Delfs, J.1
Friend, J.2
Ishimoto, S.3
Saroff, D.4
-
130
-
-
0032702435
-
Preclinical testing of neuroprotective neurotrophic factors in a model of chronic motor neuron degeneration
-
Preclinical testing of neuroprotective neurotrophic factors in a model of chronic motor neuron degeneration. AM Corse MM Bilak SR Bilak M Lehar JD Rothstein RW Kuncl, Neurobiol Dis 1999 6 335 346
-
(1999)
Neurobiol Dis
, vol.6
, pp. 335-346
-
-
Corse, A.M.1
Bilak, M.M.2
Bilak, S.R.3
Lehar, M.4
Rothstein, J.D.5
Kuncl, R.W.6
-
131
-
-
42549127816
-
Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase
-
Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase. L Tolosa M Mir VJ Asensio G Olmos J Llado, J Neurochem 2008
-
(2008)
J Neurochem
-
-
Tolosa, L.1
Mir, M.2
Asensio, V.J.3
Olmos, G.4
Llado, J.5
-
132
-
-
0026594583
-
Wobbler, a mutation affecting motoneuron survival and gonadal functions in the mouse, maps to proximal chromosome 11
-
Wobbler, a mutation affecting motoneuron survival and gonadal functions in the mouse, maps to proximal chromosome 11. K Kaupmann D Simon-Chazottes JL Guenet H Jockusch, Genomics 1992 13 39 43
-
(1992)
Genomics
, vol.13
, pp. 39-43
-
-
Kaupmann, K.1
Simon-Chazottes, D.2
Guenet, J.L.3
Jockusch, H.4
-
133
-
-
27644469489
-
Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse
-
Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse. T Schmitt-John C Drepper A Mussmann P Hahn M Kuhlmann C Thiel M Hafner A Lengeling P Heimann JM Jones MH Meisler H Jockusch, Nat Genet 2005 37 1213 1215
-
(2005)
Nat Genet
, vol.37
, pp. 1213-1215
-
-
Schmitt-John, T.1
Drepper, C.2
Mussmann, A.3
Hahn, P.4
Kuhlmann, M.5
Thiel, C.6
Hafner, M.7
Lengeling, A.8
Heimann, P.9
Jones, J.M.10
Meisler, M.H.11
Jockusch, H.12
-
134
-
-
0020429617
-
Murine motor neuron disease (the wobbler mouse): Degeneration and regeneration of the lower motor neuron
-
Murine motor neuron disease (the wobbler mouse): degeneration and regeneration of the lower motor neuron. H Mitsumoto WG Bradley, Brain 1982 105 Pt 4 811 834
-
(1982)
Brain
, vol.105
, Issue.PT 4
, pp. 811-834
-
-
Mitsumoto, H.1
Bradley, W.G.2
-
135
-
-
0028316075
-
Abnormal astrocyte differentiation and defective cellular interactions in wobbler mouse spinal cord
-
Abnormal astrocyte differentiation and defective cellular interactions in wobbler mouse spinal cord. D Hantaz-Ambroise B Blondet M Murawsky F Rieger, J Neurocytol 1994 23 179 192
-
(1994)
J Neurocytol
, vol.23
, pp. 179-192
-
-
Hantaz-Ambroise, D.1
Blondet, B.2
Murawsky, M.3
Rieger, F.4
-
136
-
-
0035800232
-
Glutamate transporters in the spinal cord of the wobbler mouse
-
Glutamate transporters in the spinal cord of the wobbler mouse. P Bigini A Bastone T Mennini, Neuroreport 2001 12 1815 1820
-
(2001)
Neuroreport
, vol.12
, pp. 1815-1820
-
-
Bigini, P.1
Bastone, A.2
Mennini, T.3
-
137
-
-
32644434547
-
Riluzole, unlike the AMPA antagonist RPR119990, reduces motor impairment and partially prevents motoneuron death in the wobbler mouse, a model of neurodegenerative disease
-
Riluzole, unlike the AMPA antagonist RPR119990, reduces motor impairment and partially prevents motoneuron death in the wobbler mouse, a model of neurodegenerative disease. E Fumagalli P Bigini S Barbera M De Paola T Mennini, Exp Neurol 2006 198 114 128
-
(2006)
Exp Neurol
, vol.198
, pp. 114-128
-
-
Fumagalli, E.1
Bigini, P.2
Barbera, S.3
De Paola, M.4
Mennini, T.5
-
138
-
-
0031080386
-
TRPM-2 expression and tunel staining in neurodegenerative diseases: Studies in wobbler and rd mice
-
TRPM-2 expression and tunel staining in neurodegenerative diseases: studies in wobbler and rd mice. P Popper DB Farber PE Micevych K Minoofar JM Bronstein, Exp Neurol 1997 143 246 254
-
(1997)
Exp Neurol
, vol.143
, pp. 246-254
-
-
Popper, P.1
Farber, D.B.2
Micevych, P.E.3
Minoofar, K.4
Bronstein, J.M.5
-
139
-
-
34648835011
-
Lack of caspase-dependent apoptosis in spinal motor neurons of the wobbler mouse
-
Lack of caspase-dependent apoptosis in spinal motor neurons of the wobbler mouse. P Bigini C Atzori E Fumagalli A Cagnotto S Barbera A Migheli T Mennini, Neurosci Lett 2007 426 106 110
-
(2007)
Neurosci Lett
, vol.426
, pp. 106-110
-
-
Bigini, P.1
Atzori, C.2
Fumagalli, E.3
Cagnotto, A.4
Barbera, S.5
Migheli, A.6
Mennini, T.7
-
140
-
-
0037175395
-
Missense mutation in the tubulin-specific chaperone e (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease
-
Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease. H Bommel G Xie W Rossoll S Wiese S Jablonka T Boehm M Sendtner, J Cell Biol 2002 159 563 569
-
(2002)
J Cell Biol
, vol.159
, pp. 563-569
-
-
Bommel, H.1
Xie, G.2
Rossoll, W.3
Wiese, S.4
Jablonka, S.5
Boehm, T.6
Sendtner, M.7
-
141
-
-
0036842251
-
A missense mutation in Tbce causes progressive motor neuronopathy in mice
-
A missense mutation in Tbce causes progressive motor neuronopathy in mice. N Martin J Jaubert P Gounon E Salido G Haase M Szatanik JL Guenet, Nat Genet 2002 32 443 447
-
(2002)
Nat Genet
, vol.32
, pp. 443-447
-
-
Martin, N.1
Jaubert, J.2
Gounon, P.3
Salido, E.4
Haase, G.5
Szatanik, M.6
Guenet, J.L.7
-
143
-
-
0032728304
-
Experimental models of amyotrophic lateral sclerosis
-
Experimental models of amyotrophic lateral sclerosis. JL Elliott, Neurobiol Dis 1999 6 310 320
-
(1999)
Neurobiol Dis
, vol.6
, pp. 310-320
-
-
Elliott, J.L.1
-
144
-
-
0030953519
-
Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors
-
Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors. G Haase P Kennel B Pettmann E Vigne S Akli F Revah H Schmalbruch A Kahn, Nat Med 1997 3 429 436
-
(1997)
Nat Med
, vol.3
, pp. 429-436
-
-
Haase, G.1
Kennel, P.2
Pettmann, B.3
Vigne, E.4
Akli, S.5
Revah, F.6
Schmalbruch, H.7
Kahn, A.8
-
145
-
-
0031723577
-
Adenovirus-mediated transfer of the neurotrophin-3 gene into skeletal muscle of pmn mice: Therapeutic effects and mechanisms of action
-
Adenovirus-mediated transfer of the neurotrophin-3 gene into skeletal muscle of pmn mice: therapeutic effects and mechanisms of action. G Haase B Pettmann E Vigne L Castelnau-Ptakhine H Schmalbruch A Kahn, J Neurol Sci 1998 160 Suppl 1 S97 105
-
(1998)
J Neurol Sci
, vol.160
, Issue.SUPPL 1
, pp. 97-105
-
-
Haase, G.1
Pettmann, B.2
Vigne, E.3
Castelnau-Ptakhine, L.4
Schmalbruch, H.5
Kahn, A.6
-
146
-
-
0034326241
-
Riluzole prolongs survival and delays muscle strength deterioration in mice with progressive motor neuronopathy (pmn)
-
Riluzole prolongs survival and delays muscle strength deterioration in mice with progressive motor neuronopathy (pmn). P Kennel F Revah GA Bohme R Bejuit P Gallix JM Stutzmann A Imperato J Pratt, J Neurol Sci 2000 180 55 61
-
(2000)
J Neurol Sci
, vol.180
, pp. 55-61
-
-
Kennel, P.1
Revah, F.2
Bohme, G.A.3
Bejuit, R.4
Gallix, P.5
Stutzmann, J.M.6
Imperato, A.7
Pratt, J.8
-
147
-
-
0024458118
-
Ultrastructural, morphometric, and immunocytochemical study of anterior horn cells in mice with "wasted" mutation
-
Ultrastructural, morphometric, and immunocytochemical study of anterior horn cells in mice with "wasted" mutation. HL Lutsep M Rodriguez, J Neuropathol Exp Neurol 1989 48 519 533
-
(1989)
J Neuropathol Exp Neurol
, vol.48
, pp. 519-533
-
-
Lutsep, H.L.1
Rodriguez, M.2
-
148
-
-
0025499594
-
Equine motor neuron disease; A preliminary report
-
Equine motor neuron disease; a preliminary report. JF Cummings A de Lahunta C George L Fuhrer BA Valentine BJ Cooper BA Summers CR Huxtable HO Mohammed, Cornell Vet 1990 80 357 379
-
(1990)
Cornell Vet
, vol.80
, pp. 357-379
-
-
Cummings, J.F.1
De Lahunta, A.2
George, C.3
Fuhrer, L.4
Valentine, B.A.5
Cooper, B.J.6
Summers, B.A.7
Huxtable, C.R.8
Mohammed, H.O.9
-
150
-
-
23844448652
-
Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress
-
Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress. H Cai X Lin C Xie FM Laird C Lai H Wen HC Chiang H Shim MH Farah A Hoke DL Price PC Wong, J Neurosci 2005 25 7567 7574
-
(2005)
J Neurosci
, vol.25
, pp. 7567-7574
-
-
Cai, H.1
Lin, X.2
Xie, C.3
Laird, F.M.4
Lai, C.5
Wen, H.6
Chiang, H.C.7
Shim, H.8
Farah, M.H.9
Hoke, A.10
Price, D.L.11
Wong, P.C.12
-
151
-
-
33745473350
-
Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities
-
Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities. RS Devon PC Orban K Gerrow MA Barbieri C Schwab LP Cao JR Helm N Bissada R Cruz-Aguado TL Davidson J Witmer M Metzler CK Lam W Tetzlaff EM Simpson JM McCaffery AE El-Husseini BR Leavitt MR Hayden, Proc Natl Acad Sci USA 2006 103 9595 9600
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9595-9600
-
-
Devon, R.S.1
Orban, P.C.2
Gerrow, K.3
Barbieri, M.A.4
Schwab, C.5
Cao, L.P.6
Helm, J.R.7
Bissada, N.8
Cruz-Aguado, R.9
Davidson, T.L.10
Witmer, J.11
Metzler, M.12
Lam, C.K.13
Tetzlaff, W.14
Simpson, E.M.15
McCaffery, J.M.16
El-Husseini, A.E.17
Leavitt, B.R.18
Hayden, M.R.19
-
152
-
-
31144448704
-
Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking
-
Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking. S Hadano SC Benn S Kakuta A Otomo K Sudo R Kunita K Suzuki-Utsunomiya H Mizumura JM Shefner GA Cox Y Iwakura RH Brown Jr JE Ikeda, Hum Mol Genet 2006 15 233 250
-
(2006)
Hum Mol Genet
, vol.15
, pp. 233-250
-
-
Hadano, S.1
Benn, S.C.2
Kakuta, S.3
Otomo, A.4
Sudo, K.5
Kunita, R.6
Suzuki-Utsunomiya, K.7
Mizumura, H.8
Shefner, J.M.9
Cox, G.A.10
Iwakura, Y.11
Jr B. H, R.12
Ikeda, J.E.13
-
153
-
-
35748930544
-
Distal axonopathy in an alsin-deficient mouse model
-
Distal axonopathy in an alsin-deficient mouse model. HX Deng H Zhai R Fu Y Shi GH Gorrie Y Yang E Liu MC Dal Canto E Mugnaini T Siddique, Hum Mol Genet 2007 16 2911 2920
-
(2007)
Hum Mol Genet
, vol.16
, pp. 2911-2920
-
-
Deng, H.X.1
Zhai, H.2
Fu, R.3
Shi, Y.4
Gorrie, G.H.5
Yang, Y.6
Liu, E.7
Dal Canto, M.C.8
Mugnaini, E.9
Siddique, T.10
-
154
-
-
41849141904
-
ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth
-
ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth. A Otomo R Kunita K Suzuki-Utsunomiya H
-
(2008)
Biochem Biophys Res Commun
, vol.370
, pp. 87-92
-
-
Otomo, A.1
Kunita, R.2
Suzuki-Utsunomiya, K.3
Mizumura, H.4
Onoe, K.5
Osuga, H.6
Hadano, S.7
Ikeda, J.E.8
-
156
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
-
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. ME Gurney H Pu AY Chiu MC Dal Canto CY Polchow DD Alexander J Caliendo A Hentati YW Kwon HX Deng W Chen P Zhai RL Sufit T Siddique, Science 1994 264 1772 1775 (Pubitemid 24227760)
-
(1994)
Science
, vol.264
, Issue.5166
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.-X.10
Chen, W.11
Zhai, P.12
Sufit, R.L.13
Siddique, T.14
-
157
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. PC Wong CA Pardo DR Borchelt MK Lee NG Copeland NA Jenkins SS Sisodia DW Cleveland DL Price, Neuron 1995 14 1105 1116
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
Lee, M.K.4
Copeland, N.G.5
Jenkins, N.A.6
Sisodia, S.S.7
Cleveland, D.W.8
Price, D.L.9
-
158
-
-
0031051485
-
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
-
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. LI Bruijn MW Becher MK Lee KL Anderson NA Jenkins NG Copeland SS Sisodia JD Rothstein DR Borchelt DL Price DW Cleveland, Neuron 1997 18 327 338
-
(1997)
Neuron
, vol.18
, pp. 327-338
-
-
Bruijn, L.I.1
Becher, M.W.2
Lee, M.K.3
Anderson, K.L.4
Jenkins, N.A.5
Copeland, N.G.6
Sisodia, S.S.7
Rothstein, J.D.8
Borchelt, D.R.9
Price, D.L.10
Cleveland, D.W.11
-
159
-
-
0034060692
-
What transgenic mice tell us about neurodegenerative disease
-
What transgenic mice tell us about neurodegenerative disease. ME Gurney, Bioessays 2000 22 297 304
-
(2000)
Bioessays
, vol.22
, pp. 297-304
-
-
Gurney, M.E.1
-
160
-
-
0028888945
-
Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
-
Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. ME Ripps GW Huntley PR Hof JH Morrison JW Gordon, Proc Natl Acad Sci USA 1995 92 689 693
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 689-693
-
-
Ripps, M.E.1
Huntley, G.W.2
Hof, P.R.3
Morrison, J.H.4
Gordon, J.W.5
-
161
-
-
0037022339
-
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
-
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). DS Howland J Liu Y She B Goad NJ Maragakis B Kim J Erickson J Kulik L DeVito G Psaltis LJ DeGennaro DW Cleveland JD Rothstein, Proc Natl Acad Sci USA 2002 99 1604 1609
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1604-1609
-
-
Howland, D.S.1
Liu, J.2
She, Y.3
Goad, B.4
Maragakis, N.J.5
Kim, B.6
Erickson, J.7
Kulik, J.8
Devito, L.9
Psaltis, G.10
Degennaro, L.J.11
Cleveland, D.W.12
Rothstein, J.D.13
-
162
-
-
0035575761
-
Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: Associated mutations develop motor neuron disease
-
Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease. M Nagai M Aoki I Miyoshi M Kato P Pasinelli N Kasai RH Brown Jr Y Itoyama, J Neurosci 2001 21 9246 9254 11717358
-
(2001)
J Neurosci
, vol.21
, pp. 9246-9254
-
-
Nagai, M.1
Aoki, M.2
Miyoshi, I.3
Kato, M.4
Pasinelli, P.5
Kasai, N.6
Jr B. H, R.7
Itoyama, Y.8
-
163
-
-
0032949602
-
Oxidative stress and motor neurone disease
-
Oxidative stress and motor neurone disease. MR Cookson PJ Shaw, Brain Pathol 1999 9 165 186
-
(1999)
Brain Pathol
, vol.9
, pp. 165-186
-
-
Cookson, M.R.1
Shaw, P.J.2
-
164
-
-
34948822926
-
Redox modifier genes in amyotrophic lateral sclerosis in mice
-
Redox modifier genes in amyotrophic lateral sclerosis in mice. JJ Marden MM Harraz AJ Williams K Nelson M Luo H Paulson JF Engelhardt, J Clin Invest 2007 117 2913 2919
-
(2007)
J Clin Invest
, vol.117
, pp. 2913-2919
-
-
Marden, J.J.1
Harraz, M.M.2
Williams, A.J.3
Nelson, K.4
Luo, M.5
Paulson, H.6
Engelhardt, J.F.7
-
165
-
-
36749049874
-
Glutamate excitotoxicity and therapeutic targets for amyotrophic lateral sclerosis
-
Glutamate excitotoxicity and therapeutic targets for amyotrophic lateral sclerosis. JC Corona LB Tovar-y-Romo R Tapia, Expert Opin Ther Targets 2007 11 1415 1428
-
(2007)
Expert Opin Ther Targets
, vol.11
, pp. 1415-1428
-
-
Corona, J.C.1
Tovar-Y-Romo, L.B.2
Tapia, R.3
-
166
-
-
21844454460
-
Mitochondria in amyotrophic lateral sclerosis: A trigger and a target
-
DOI 10.1159/000085063
-
Mitochondria in amyotrophic lateral sclerosis: a trigger and a target. L Dupuis JL Gonzalez de Aguilar H Oudart M de Tapia L Barbeito JP Loeffler, Neurodegener Dis 2004 1 245 254 (Pubitemid 40960427)
-
(2004)
Neurodegenerative Diseases
, vol.1
, Issue.6
, pp. 245-254
-
-
Dupuis, L.1
Gonzalez De Aguilar, J.-L.2
Oudart, H.3
De Tapia, M.4
Barbeito, L.5
Loeffler, J.-P.6
-
167
-
-
33646241740
-
Mitochondrial dysfunction and amyotrophic lateral sclerosis
-
Mitochondrial dysfunction and amyotrophic lateral sclerosis. I Hervias MF Beal G Manfredi, Muscle Nerve 2006 33 598 608
-
(2006)
Muscle Nerve
, vol.33
, pp. 598-608
-
-
Hervias, I.1
Beal, M.F.2
Manfredi, G.3
-
168
-
-
23644437653
-
Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene
-
Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene. S Sasaki H Warita K Abe M Iwata, Acta Neuropathol 2005 110 48 56
-
(2005)
Acta Neuropathol
, vol.110
, pp. 48-56
-
-
Sasaki, S.1
Warita, H.2
Abe, K.3
Iwata, M.4
-
169
-
-
38049097948
-
Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice
-
Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice. D Kieran I Woods A Villunger A Strasser JH Prehn, Proc Natl Acad Sci USA 2007 104 20606 20611
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20606-20611
-
-
Kieran, D.1
Woods, I.2
Villunger, A.3
Strasser, A.4
Prehn, J.H.5
-
170
-
-
33947323759
-
Lost in translation: Treatment trials in the SOD1 mouse and in human ALS
-
Lost in translation: treatment trials in the SOD1 mouse and in human ALS. M Benatar, Neurobiol Dis 2007 26 1 13
-
(2007)
Neurobiol Dis
, vol.26
, pp. 1-13
-
-
Benatar, M.1
-
171
-
-
39349107014
-
Design, power, and interpretation of studies in the standard murine model of ALS
-
Design, power, and interpretation of studies in the standard murine model of ALS. S Scott JE Kranz J Cole JM Lincecum K Thompson N Kelly A Bostrom J Theodoss BM Al-Nakhala FG Vieira J Ramasubbu JA Heywood, Amyotroph Lateral Scler 2008 9 4 15
-
(2008)
Amyotroph Lateral Scler
, vol.9
, pp. 4-15
-
-
Scott, S.1
Kranz, J.E.2
Cole, J.3
Lincecum, J.M.4
Thompson, K.5
Kelly, N.6
Bostrom, A.7
Theodoss, J.8
Al-Nakhala, B.M.9
Vieira, F.G.10
Ramasubbu, J.11
Heywood, J.A.12
-
172
-
-
46249106545
-
Calpain Inhibition Protects Spinal Motoneurons from the Excitotoxic Effects of AMPA in vivo
-
Calpain Inhibition Protects Spinal Motoneurons from the Excitotoxic Effects of AMPA In vivo. JC Corona R Tapia, Neurochem Res 2008
-
(2008)
Neurochem Res
-
-
Corona, J.C.1
Tapia, R.2
-
173
-
-
0030814058
-
Blocking effect of 1-naphthyl acetyl spermine on Ca(2+)-permeable AMPA receptors in cultured rat hippocampal neurons
-
Blocking effect of 1-naphthyl acetyl spermine on Ca(2+)-permeable AMPA receptors in cultured rat hippocampal neurons. M Koike M Iino S Ozawa, Neurosci Res 1997 29 27 36
-
(1997)
Neurosci Res
, vol.29
, pp. 27-36
-
-
Koike, M.1
Iino, M.2
Ozawa, S.3
-
175
-
-
0037082328
-
Blockade of Ca2+-permeable AMPA/kainate channels decreases oxygen-glucose deprivation-induced Zn2+ accumulation and neuronal loss in hippocampal pyramidal neurons
-
Blockade of Ca2+-permeable AMPA/kainate channels decreases oxygen-glucose deprivation-induced Zn2+ accumulation and neuronal loss in hippocampal pyramidal neurons. HZ Yin SL Sensi F Ogoshi JH Weiss, J Neurosci 2002 22 1273 1279
-
(2002)
J Neurosci
, vol.22
, pp. 1273-1279
-
-
Yin, H.Z.1
Sensi, S.L.2
Ogoshi, F.3
Weiss, J.H.4
-
176
-
-
34948909599
-
Vascular endothelial growth factor prevents paralysis and motoneuron death in a rat model of excitotoxic spinal cord neurodegeneration
-
Vascular endothelial growth factor prevents paralysis and motoneuron death in a rat model of excitotoxic spinal cord neurodegeneration. LB Tovar-y-Romo A Zepeda R Tapia, J Neuropathol Exp Neurol 2007 66 913 922
-
(2007)
J Neuropathol Exp Neurol
, vol.66
, pp. 913-922
-
-
Tovar-Y-Romo, L.B.1
Zepeda, A.2
Tapia, R.3
|