-
1
-
-
0028998398
-
Amyotrophic lateral sclerosis is a multifactorial disease
-
Eisen, A. 1995. Amyotrophic lateral sclerosis is a multifactorial disease. Muscle and Nerve 18:741-752.
-
(1995)
Muscle and Nerve
, vol.18
, pp. 741-752
-
-
Eisen, A.1
-
2
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J. P., Deng, H-X., Rahmani, Z., Krizus, A., McKenna-Yasek, D., Cayabyab, A., Gaston, S. M., Berger, R., Tanzi, R. E., Halperin, J. J., Herzfeldt, B., Van den Bergh, R., Hung, W-Y., Bird, T., Deng, G., Mulder, D. W., Smyth, C., Laing, N. G., Soriano, E., Pericak-Vance, M. A., Haines, J., Rouleau, G. A., Gusella, J. S., Horvitz, H. R., and Brown, R. H. Jr. 1993. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362:59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.-X.10
Rahmani, Z.11
Krizus, A.12
McKenna-Yasek, D.13
Cayabyab, A.14
Gaston, S.M.15
Berger, R.16
Tanzi, R.E.17
Halperin, J.J.18
Herzfeldt, B.19
Van Den Bergh, R.20
Hung, W.-Y.21
Bird, T.22
Deng, G.23
Mulder, D.W.24
Smyth, C.25
Laing, N.G.26
Soriano, E.27
Pericak-Vance, M.A.28
Haines, J.29
Rouleau, G.A.30
Gusella, J.S.31
Horvitz, H.R.32
Brown Jr., R.H.33
more..
-
3
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase
-
Deng, H. X., Hentati, A., Tainer, J. A., Iqbal, Z., Cayabyab, A., Hung, W-Y., Getzoff, E. D., Hu, P., Herzfeldt, B., Roos, R. P., Warner, C., Deng, G., Soriano, E., Smyth, C., Parge, H. E., Ahmed, A., Roses, A. D., Hallewell, R. A., Pericak-Vance, M. A., and Siddique, T. 1993. Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science 261:1047-1050.
-
(1993)
Science
, vol.261
, pp. 1047-1050
-
-
Deng, H.X.1
Hentati, A.2
Tainer, J.A.3
Iqbal, Z.4
Cayabyab, A.5
Hung, W.-Y.6
Getzoff, E.D.7
Hu, P.8
Herzfeldt, B.9
Roos, R.P.10
Warner, C.11
Deng, G.12
Soriano, E.13
Smyth, C.14
Parge, H.E.15
Ahmed, A.16
Roses, A.D.17
Hallewell, R.A.18
Pericak-Vance, M.A.19
Siddique, T.20
more..
-
4
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
-
Gurney, M. E., Pu, H., Chiu, A. Y., Dal Canto, M. C., Polchow, C. Y., Alexander, D. D., Caliendo, J., Hentati, A., Kwon, Y. W., Deng, H-X., Chen, W., Zhai, P., Sum, R. L., and Siddique, T. 1994. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 264:1772-1775.
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.-X.10
Chen, W.11
Zhai, P.12
Sum, R.L.13
Siddique, T.14
-
5
-
-
0029010496
-
Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase
-
Andersen, P. M., Nilsson, P., Ala-Hurula, V., Keranen, M., Tarvainen, I., Haltia, T., Nilsson, L., Binzer, M., Forsgren, L., and Marklund, S. L. 1995. Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase. Genetics 10:61-66.
-
(1995)
Genetics
, vol.10
, pp. 61-66
-
-
Andersen, P.M.1
Nilsson, P.2
Ala-Hurula, V.3
Keranen, M.4
Tarvainen, I.5
Haltia, T.6
Nilsson, L.7
Binzer, M.8
Forsgren, L.9
Marklund, S.L.10
-
6
-
-
0028813380
-
Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function
-
Borchelt, D. R., Guarnieri, M., Wong, P. C., Lee, M. K., Slunt, H. S., Xu, Z., Sisodia, S. S., Price, D. L., and Cleveland, D. W. 1995. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. J. Biol. Chem. 270:3234-3238.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3234-3238
-
-
Borchelt, D.R.1
Guarnieri, M.2
Wong, P.C.3
Lee, M.K.4
Slunt, H.S.5
Xu, Z.6
Sisodia, S.S.7
Price, D.L.8
Cleveland, D.W.9
-
7
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
Ames, B. N., Shigenaga, M. K., and Hagen, T. M. 1993. Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA. 90:7915-7922.
-
(1993)
Proc. Natl. Acad. Sci. USA.
, vol.90
, pp. 7915-7922
-
-
Ames, B.N.1
Shigenaga, M.K.2
Hagen, T.M.3
-
8
-
-
0023915949
-
Lipid peroxidation measured as thiobarbituric acid reactive substances in tissue slices: Characterization and comparison with homogenates and microsomes
-
Fraga, C. G., Leibovitz, B. E., and Tappel, A. L. 1988. Lipid peroxidation measured as thiobarbituric acid reactive substances in tissue slices: characterization and comparison with homogenates and microsomes. Free Radical. Biol. Med. 4:155-161.
-
(1988)
Free Radical. Biol. Med.
, vol.4
, pp. 155-161
-
-
Fraga, C.G.1
Leibovitz, B.E.2
Tappel, A.L.3
-
9
-
-
0028054149
-
Measurement of antioxidants in human blood plasma
-
Motchnik, P. M., Frei, B., and Ames, B. N. 1994. Measurement of antioxidants in human blood plasma. Meth. Enzymol. 234:269-279.
-
(1994)
Meth. Enzymol.
, vol.234
, pp. 269-279
-
-
Motchnik, P.M.1
Frei, B.2
Ames, B.N.3
-
10
-
-
0021288878
-
Superoxide dismutase assays
-
Flohé, L., and Otting F. 1984. Superoxide dismutase assays. Meth. Enzymol. 105:93-104.
-
(1984)
Meth. Enzymol.
, vol.105
, pp. 93-104
-
-
Flohé, L.1
Otting, F.2
-
11
-
-
0023181066
-
Age-related changes in oxidized proteins
-
Oliver, C. N., Bong-whan A., Moerman, E. J., Goldstein, S, and Stadtman, E. R. 1987. Age-related changes in oxidized proteins. J. Biol. Chem. 262:5488-5491.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 5488-5491
-
-
Oliver, C.N.1
Bong-whan, A.2
Moerman, E.J.3
Goldstein, S.4
Stadtman, E.R.5
-
12
-
-
0025102226
-
Determination of carbonyl content in oxidatively modified proteins
-
Levine, R. L., Garland, D., Oliver, C., Amici, A., Climent, I., Lenz, A., Ahn, B., Shaltiel, S., and Stadtman, E. 1990. Determination of carbonyl content in oxidatively modified proteins. Meth. Enzymol. 186:464-478.
-
(1990)
Meth. Enzymol.
, vol.186
, pp. 464-478
-
-
Levine, R.L.1
Garland, D.2
Oliver, C.3
Amici, A.4
Climent, I.5
Lenz, A.6
Ahn, B.7
Shaltiel, S.8
Stadtman, E.9
-
14
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principles of protein-dye binding
-
Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principles of protein-dye binding. Anal. Biochem. 72:248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
15
-
-
0028940996
-
Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis
-
Bowling, A. C., Barkowski, E. E., McKenna-Yasek, D., Sapp, P., Horvitz, R. H., Beal F., and Brown, R. H. Jr. 1995. Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis. J. Neurochem. 64:2366-2369.
-
(1995)
J. Neurochem.
, vol.64
, pp. 2366-2369
-
-
Bowling, A.C.1
Barkowski, E.E.2
McKenna-Yasek, D.3
Sapp, P.4
Horvitz, R.H.5
Beal, F.6
Brown Jr., R.H.7
-
16
-
-
0027452090
-
Mild ALS in Japan associated with novel SOD mutation
-
Ogasawara, M., Matsubara, Y., Narisawa, K., Aoki, M., Nakamura, S., Itoyama, Y., and Abe, K. 1993. Mild ALS in Japan associated with novel SOD mutation. Nature Genet. 5:323-324.
-
(1993)
Nature Genet.
, vol.5
, pp. 323-324
-
-
Ogasawara, M.1
Matsubara, Y.2
Narisawa, K.3
Aoki, M.4
Nakamura, S.5
Itoyama, Y.6
Abe, K.7
-
17
-
-
0027952571
-
Cu/Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis
-
Robberecht, W., Sapp, P., Viaene, M. K., Rosen, D., McKenna-Yasek, D., Haines, J., Horvitz, R., Theys, P., and Brown, R. Jr. 1994. Cu/Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis. J. Neurochem. 62:384-387.
-
(1994)
J. Neurochem.
, vol.62
, pp. 384-387
-
-
Robberecht, W.1
Sapp, P.2
Viaene, M.K.3
Rosen, D.4
McKenna-Yasek, D.5
Haines, J.6
Horvitz, R.7
Theys, P.8
Brown Jr., R.9
-
18
-
-
0028971936
-
Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis
-
Abe, K., Pan, L. H., Watanabe, M., Kato, T., and Itoyama, Y. 1995. Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis. Neurosci. Letters. 199:152-154.
-
(1995)
Neurosci. Letters.
, vol.199
, pp. 152-154
-
-
Abe, K.1
Pan, L.H.2
Watanabe, M.3
Kato, T.4
Itoyama, Y.5
-
19
-
-
0027359334
-
Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
-
Bowling, A. C., Schulz, J. B., Brown, R. H. Jr., and Beal, F. 1993. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J. Neurochem. 61:2322-2325.
-
(1993)
J. Neurochem.
, vol.61
, pp. 2322-2325
-
-
Bowling, A.C.1
Schulz, J.B.2
Brown Jr., R.H.3
Beal, F.4
-
20
-
-
0028343223
-
A frequent Ala 4 to Val mutation in exon 1 of the superoxide dismutase-1 gene: Decreased enzyme activity is associated with a rapidly progressive familial ALS
-
Rosen, D. R., Bowling, A. C., Patterson, D., Usdin, T. B., Sapp, P., Mezey, E., McKenna-Yasek, D., O'Regan, J. P., Rhamani, Z., Ferrante, R. J., Brownstein, M. J., Kowall, N. W., Beal, M. F., Horvitz, H. R., and Brown, R. H. Jr. 1994. A frequent Ala 4 to Val mutation in exon 1 of the superoxide dismutase-1 gene: decreased enzyme activity is associated with a rapidly progressive familial ALS. Hum. Mol. Genet. 3:981-987.
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 981-987
-
-
Rosen, D.R.1
Bowling, A.C.2
Patterson, D.3
Usdin, T.B.4
Sapp, P.5
Mezey, E.6
McKenna-Yasek, D.7
O'Regan, J.P.8
Rhamani, Z.9
Ferrante, R.J.10
Brownstein, M.J.11
Kowall, N.W.12
Beal, M.F.13
Horvitz, H.R.14
Brown Jr., R.H.15
-
21
-
-
0026086025
-
Risk of angina pectoris and plasma concentrations of vitamins A,C, and E and carotene
-
Riemersma, R. A., Wood, D. A., Macintyre, C. C. A., Elton, R. A., Gey, K. F., and Oliver, M. F. 1991, Risk of angina pectoris and plasma concentrations of vitamins A,C, and E and carotene. Lancet 337:1-5.
-
(1991)
Lancet
, vol.337
, pp. 1-5
-
-
Riemersma, R.A.1
Wood, D.A.2
Macintyre, C.C.A.3
Elton, R.A.4
Gey, K.F.5
Oliver, M.F.6
-
22
-
-
0028788091
-
Superoxide dismutase and free radicals in sporadic amyotrophic lateral sclerosis: Relationship to clinical data
-
Ihara, Y., Mori, A., Hayabara, T., Kawai, M., Namba, R., Nobukuni, K., Sato, K., and Kibata, M. 1995. Superoxide dismutase and free radicals in sporadic amyotrophic lateral sclerosis: relationship to clinical data. J. Neurol. Sci. 134:51-56.
-
(1995)
J. Neurol. Sci.
, vol.134
, pp. 51-56
-
-
Ihara, Y.1
Mori, A.2
Hayabara, T.3
Kawai, M.4
Namba, R.5
Nobukuni, K.6
Sato, K.7
Kibata, M.8
-
23
-
-
0029939471
-
A gain of function of an amyotrophic lateral sclerosis-associated Cu, Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide
-
Yim, M. B., Kang, J. H., Yim, H. S., Kwak, H. S. Chock, P. B., and Stadtman, E. R. 1996. A gain of function of an amyotrophic lateral sclerosis-associated Cu, Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide. Proc. Natl. Acad. Sci. USA. 93:5709-5714.
-
(1996)
Proc. Natl. Acad. Sci. USA.
, vol.93
, pp. 5709-5714
-
-
Yim, M.B.1
Kang, J.H.2
Yim, H.S.3
Kwak, H.S.4
Chock, P.B.5
Stadtman, E.R.6
-
24
-
-
0029671220
-
Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis
-
Wiedau-Pazos, M., Goto, J. J., Rabizadeh, S., Gralla, E. B., Roe, J. A., Lee, M. K., Valentine, J. S., and Bredesen, D. E. 1996. Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science. 271:515-518.
-
(1996)
Science.
, vol.271
, pp. 515-518
-
-
Wiedau-Pazos, M.1
Goto, J.J.2
Rabizadeh, S.3
Gralla, E.B.4
Roe, J.A.5
Lee, M.K.6
Valentine, J.S.7
Bredesen, D.E.8
|