-
1
-
-
0035516124
-
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
-
Cleveland DW, Rothstein JD. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2001;2:806-819.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
2
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
Bruijn LI, Miller TM, Cleveland DW. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 2004;27:723-749.
-
(2004)
Annu Rev Neurosci
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
3
-
-
0028334717
-
Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35
-
Hentati A, Bejaoui K, Pericak-Vance MA, et al. Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35. Nat Genet 1994;7:425-428.
-
(1994)
Nat Genet
, vol.7
, pp. 425-428
-
-
Hentati, A.1
Bejaoui, K.2
Pericak-Vance, M.A.3
-
4
-
-
0032443063
-
Refined mapping and characterization of the recessive familial amyotrophic lateral sclerosis locus (ALS2) on chromosome 2q33
-
Hosler BA, Sapp PC, Berger R, et al. Refined mapping and characterization of the recessive familial amyotrophic lateral sclerosis locus (ALS2) on chromosome 2q33. Neurogenetics 1998;2:34-42.
-
(1998)
Neurogenetics
, vol.2
, pp. 34-42
-
-
Hosler, B.A.1
Sapp, P.C.2
Berger, R.3
-
5
-
-
0032949267
-
A yeast artificial chromosome-based physical map of the juvenile amyotrophic lateral sclerosis (ALS2) critical region on human chromosome 2q33-q34
-
Hadano S, Nichol K, Brinkman RR, et al. A yeast artificial chromosome-based physical map of the juvenile amyotrophic lateral sclerosis (ALS2) critical region on human chromosome 2q33-q34. Genomics 1999;55:106-112.
-
(1999)
Genomics
, vol.55
, pp. 106-112
-
-
Hadano, S.1
Nichol, K.2
Brinkman, R.R.3
-
6
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
Hadano S, Hand CK, Osuga H, et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet 2001;29:166-173.
-
(2001)
Nat Genet
, vol.29
, pp. 166-173
-
-
Hadano, S.1
Hand, C.K.2
Osuga, H.3
-
7
-
-
0034785509
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
Yang Y, Hentati A, Deng HX, et al. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat Genet 2001;29:160-165.
-
(2001)
Nat Genet
, vol.29
, pp. 160-165
-
-
Yang, Y.1
Hentati, A.2
Deng, H.X.3
-
8
-
-
0025237394
-
Hereditary motor system diseases (chronic juvenile amyotrophic lateral sclerosis). Conditions combining a bilateral pyramidal syndrome with limb and bulbar amyotrophy
-
Ben Hamida M, Hentati F, Ben Hamida C. Hereditary motor system diseases (chronic juvenile amyotrophic lateral sclerosis). Conditions combining a bilateral pyramidal syndrome with limb and bulbar amyotrophy. Brain 1990;113(pt 2):347-363.
-
(1990)
Brain
, vol.113
, Issue.PART 2
, pp. 347-363
-
-
Ben Hamida, M.1
Hentati, F.2
Ben Hamida, C.3
-
9
-
-
0036724052
-
Infantile-onset ascending hereditary spastic paralysis is associated with mutations in the alsin gene
-
Eymard-Pierre E, Lesca G, Dollet S, et al. Infantile-onset ascending hereditary spastic paralysis is associated with mutations in the alsin gene. Am J Hum Genet 2002;71:518-527.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 518-527
-
-
Eymard-Pierre, E.1
Lesca, G.2
Dollet, S.3
-
10
-
-
0037234133
-
An ALS2 gene mutation causes hereditary spastic paraplegia in a Pakistani kindred
-
Gros-Louis F, Meijer IA, Hand CK, et al. An ALS2 gene mutation causes hereditary spastic paraplegia in a Pakistani kindred. Ann Neurol 2003;53:144-145.
-
(2003)
Ann Neurol
, vol.53
, pp. 144-145
-
-
Gros-Louis, F.1
Meijer, I.A.2
Hand, C.K.3
-
11
-
-
0042914405
-
The first nonsense mutation in alsin results in a homogeneous phenotype of infantile-onset ascending spastic paralysis with bulbar involvement in two siblings
-
Devon R, Helm J, Rouleau G, et al. The first nonsense mutation in alsin results in a homogeneous phenotype of infantile-onset ascending spastic paralysis with bulbar involvement in two siblings. Clin Genet 2003;64:210-215.
-
(2003)
Clin Genet
, vol.64
, pp. 210-215
-
-
Devon, R.1
Helm, J.2
Rouleau, G.3
-
12
-
-
0030019925
-
Infantile onset of hereditary ascending spastic paralysis with bulbar involvement
-
Lerman-Sagie T, Filiano J, Smith DW, Korson M. Infantile onset of hereditary ascending spastic paralysis with bulbar involvement. J Child Neurol 1996;11:54-57.
-
(1996)
J Child Neurol
, vol.11
, pp. 54-57
-
-
Lerman-Sagie, T.1
Filiano, J.2
Smith, D.W.3
Korson, M.4
-
13
-
-
0028891994
-
Familial childhood primary lateral sclerosis with associated gaze paresis
-
Gascon GG, Chavis P, Yaghmour A, et al. Familial childhood primary lateral sclerosis with associated gaze paresis. Neuropediatrics 1995;26:313-319.
-
(1995)
Neuropediatrics
, vol.26
, pp. 313-319
-
-
Gascon, G.G.1
Chavis, P.2
Yaghmour, A.3
-
14
-
-
27644488582
-
Novel mutation in the ALS2 gene in juvenile amyotrophic lateral sclerosis
-
Kress JA, Kuhnlein P, Winter P, et al. Novel mutation in the ALS2 gene in juvenile amyotrophic lateral sclerosis. Ann Neurol 2005;58:800-803.
-
(2005)
Ann Neurol
, vol.58
, pp. 800-803
-
-
Kress, J.A.1
Kuhnlein, P.2
Winter, P.3
-
15
-
-
33744816471
-
Novel missense mutation in ALS2 gene results in IAHSP
-
Eymard-Pierre E, Yamanaka K, Haeussler M, et al. Novel missense mutation in ALS2 gene results in IAHSP. Ann Neurol 2006;59:976-980.
-
(2006)
Ann Neurol
, vol.59
, pp. 976-980
-
-
Eymard-Pierre, E.1
Yamanaka, K.2
Haeussler, M.3
-
16
-
-
0346734108
-
Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease
-
Yamanaka K, Vande Velde C, Eymard-Pierre E, et al. Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease. Proc Natl Acad Sci U S A 2003;100:16041-16046.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 16041-16046
-
-
Yamanaka, K.1
Vande Velde, C.2
Eymard-Pierre, E.3
-
17
-
-
0041308082
-
ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics
-
Otomo A, Hadano S, Okada T, et al. ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics. Hum Mol Genet 2003;12: 1671-1687.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1671-1687
-
-
Otomo, A.1
Hadano, S.2
Okada, T.3
-
19
-
-
14244264186
-
A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death
-
Kanekura K, Hashimoto Y, Kita Y, et al. A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. J Biol Chem 2005;280:4532-4543.
-
(2005)
J Biol Chem
, vol.280
, pp. 4532-4543
-
-
Kanekura, K.1
Hashimoto, Y.2
Kita, Y.3
-
20
-
-
27144530084
-
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth
-
Tudor EL, Perkinton MS, Schmidt A, et al. ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth. J Biol Chem 2005;280:34735-34740.
-
(2005)
J Biol Chem
, vol.280
, pp. 34735-34740
-
-
Tudor, E.L.1
Perkinton, M.S.2
Schmidt, A.3
-
21
-
-
31144448704
-
Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking
-
Hadano S, Benn SC, Kakuta S, et al. Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking. Hum Mol Genet 2006;15:233-250.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 233-250
-
-
Hadano, S.1
Benn, S.C.2
Kakuta, S.3
-
22
-
-
23844448652
-
Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress
-
Cai H, Lin X, Xie C, et al. Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress. J Neurosci 2005;25: 7567-7574.
-
(2005)
J Neurosci
, vol.25
, pp. 7567-7574
-
-
Cai, H.1
Lin, X.2
Xie, C.3
-
26
-
-
0031051485
-
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
-
Bruijn LI, Becher MW, Lee MK, et al. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron 1997;18:327-338.
-
(1997)
Neuron
, vol.18
, pp. 327-338
-
-
Bruijn, L.I.1
Becher, M.W.2
Lee, M.K.3
-
27
-
-
0032486428
-
Axonal swellings and degeneration in mice lacking the major proteolipid of myelin
-
Griffiths I, Klugmann M, Anderson T, et al. Axonal swellings and degeneration in mice lacking the major proteolipid of myelin. Science 1998;280:1610-1613.
-
(1998)
Science
, vol.280
, pp. 1610-1613
-
-
Griffiths, I.1
Klugmann, M.2
Anderson, T.3
-
28
-
-
1342310772
-
Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport
-
Ferreirinha F, Quattrini A, Pirozzi M, et al. Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport. J Clin Invest 2004;113:231-242.
-
(2004)
J Clin Invest
, vol.113
, pp. 231-242
-
-
Ferreirinha, F.1
Quattrini, A.2
Pirozzi, M.3
-
30
-
-
0037465372
-
Infantile ascending hereditary spastic paralysis (IAHSP): Clinical features in 11 families
-
Lesca G, Eymard-Pierre E, Santorelli FM, et al. Infantile ascending hereditary spastic paralysis (IAHSP): clinical features in 11 families. Neurology 2003;60:674-682.
-
(2003)
Neurology
, vol.60
, pp. 674-682
-
-
Lesca, G.1
Eymard-Pierre, E.2
Santorelli, F.M.3
-
31
-
-
0029042577
-
Anatomy, development and lesion-induced plasticity of rodent corticospinal tract
-
Terashima T. Anatomy, development and lesion-induced plasticity of rodent corticospinal tract. Neurosci Res 1995;22: 139-161.
-
(1995)
Neurosci Res
, vol.22
, pp. 139-161
-
-
Terashima, T.1
-
32
-
-
1942420813
-
The dorsolateral corticospinal tract in mice: An alternative route for corticospinal input to caudal segments following dorsal column lesions
-
Steward O, Zheng B, Ho C, et al. The dorsolateral corticospinal tract in mice: an alternative route for corticospinal input to caudal segments following dorsal column lesions. J Comp Neurol 2004;472:463-477.
-
(2004)
J Comp Neurol
, vol.472
, pp. 463-477
-
-
Steward, O.1
Zheng, B.2
Ho, C.3
-
33
-
-
0032750048
-
The hereditary spastic paraplegias
-
Reid E. The hereditary spastic paraplegias. J Neurol 1999;246: 995-1003.
-
(1999)
J Neurol
, vol.246
, pp. 995-1003
-
-
Reid, E.1
-
34
-
-
0037392912
-
An electron microscopic examination of the corticospinal projection to the cervical spinal cord in the rat: Lack of evidence for cortico-motoneuronal synapses
-
Yang HW, Lemon RN. An electron microscopic examination of the corticospinal projection to the cervical spinal cord in the rat: lack of evidence for cortico-motoneuronal synapses. Exp Brain Res 2003;149:458-469.
-
(2003)
Exp Brain Res
, vol.149
, pp. 458-469
-
-
Yang, H.W.1
Lemon, R.N.2
-
35
-
-
4544335087
-
ALS2CL, the novel protein highly homologous to the carboxy-terminal half of ALS2, binds to Rab5 and modulates endosome dynamics
-
Hadano S, Otomo A, Suzuki-Utsunomiya K, et al. ALS2CL, the novel protein highly homologous to the carboxy-terminal half of ALS2, binds to Rab5 and modulates endosome dynamics. FEBS Lett 2004;575:64-70.
-
(2004)
FEBS Lett
, vol.575
, pp. 64-70
-
-
Hadano, S.1
Otomo, A.2
Suzuki-Utsunomiya, K.3
|