Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade

Experimental Neurology

Volumn 199, Issue 2, 2006, Pages 281-290

  Tovar y Romo, Luis B ^a   Tapia, Ricardo ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Amyotrophic lateral sclerosis; Excitotoxicity; G93A mice; Glutamate; Hippocampus; HSP70; Microdialysis; Motor cortex

Indexed keywords

2,4 PYRROLIDINEDICARBOXYLIC ACID; 4 AMINOPYRIDINE; BIOLOGICAL MARKER; COPPER ZINC SUPEROXIDE DISMUTASE; DIZOCILPINE; GLUTAMIC ACID; HEAT SHOCK PROTEIN 70; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

AMINO ACID TRANSPORT; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEGENERATION; BRAIN NERVE CELL; BRAIN PERFUSION; CELL TRANSPORT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CONVULSION; EXCITOTOXICITY; EXTRACELLULAR MATRIX; FAMILIAL DISEASE; GENE MUTATION; HIPPOCAMPUS; MICRODIALYSIS; MOTOR CORTEX; MOUSE; NERVE CELL DEGENERATION; NERVE CELL LESION; NERVE ENDING; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SECRETION; TRANSGENIC MOUSE; WILD TYPE;

4-AMINOPYRIDINE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BIOLOGICAL TRANSPORT; DICARBOXYLIC ACIDS; DISEASE MODELS, ANIMAL; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; EXTRACELLULAR SPACE; GLUTAMIC ACID; HSP72 HEAT-SHOCK PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MICRODIALYSIS; NEURONS; NEUROTRANSMITTER UPTAKE INHIBITORS; PYRROLIDINES; SUPEROXIDE DISMUTASE;

EID: 33745270015     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2005.11.005     Document Type: Article

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