Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells

Journal of the Neurological Sciences

Volumn 232, Issue 1-2, 2005, Pages 95-103

  Rizzardini, Milena ^a   Mangolini, Alessandra ^a   Lupi, Monica ^a   Ubezio, Paolo ^a   Bendotti, Caterina ^a   Cantoni, Lavinia ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Amyotrophic lateral sclerosis; Cu Zn superoxide dismutase; Flow cytometry; Mitochondria; Mitochondrial membrane potential; Motor neuron(s); Neurodegeneration; Oxidative stress

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MUTANT PROTEIN; REACTIVE OXYGEN METABOLITE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL GROWTH; CELL LINE; CELL MEMBRANE DEPOLARIZATION; CELL POPULATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; EXPERIMENTAL MODEL; FLOW CYTOMETRY; GENETIC TRANSFECTION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL TOXICITY; MOTONEURON; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

EID: 17844364182     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2005.02.004     Document Type: Article

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