Blockade of Ca2+-permeable AMPA/kainate channels decreases oxygen-glucose deprivation-induced Zn2+ accumulation and neuronal loss in hippocampal pyramidal neurons

Journal of Neuroscience

Volumn 22, Issue 4, 2002, Pages 1273-1279

  Yin, Hong Z ^a   Sensi, Stefano L ^a   Ogoshi, Fumio ^a,b   Weiss, John H ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CHIETI   (Italy)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

AMPA; Glutamate; Hippocampal slice; Ischemia; Naphthyl acetyl spermine; Neurotoxicity; Pyramidal neuron; Timm's stain; Zinc

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; GLUCOSE; KAINIC ACID; OXYGEN; ZINC; 1 NAPHTHYLACETYLSPERMINE; 1-NAPHTHYLACETYLSPERMINE; AMINO ACID RECEPTOR BLOCKING AGENT; AMPA RECEPTOR; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; COBALT; DRUG DERIVATIVE; KAINIC ACID RECEPTOR; SPERMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HIPPOCAMPUS; HYPOXIA; ISCHEMIA; LABELING INDEX; MOUSE; NERVE DEGENERATION; NERVE INJURY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RECEPTOR BLOCKING; SYNAPTIC TRANSMISSION; ANIMAL; BRAIN HYPOXIA; CELL CULTURE; CELL HYPOXIA; COCULTURE; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; IN VITRO STUDY; METABOLISM; PHYSIOLOGY;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CELL HYPOXIA; CELLS, CULTURED; COBALT; COCULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; GLUCOSE; HIPPOCAMPUS; HYPOXIA, BRAIN; MICE; PYRAMIDAL CELLS; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID; SPERMINE; ZINC;

EID: 0037082328     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-04-01273.2002     Document Type: Article

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