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Volumn 10, Issue 3-4, 1996, Pages 249-258

Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: An immunohistochemical study

Author keywords

3'5' cyclic guanosine monophosphate (cGMP); Amyotrophic lateral sclerosis (ALS); Light neurofilament (NF L); Motor neuron (MN); Nitric oxide (NO); Peroxynitrite (ONOO ); Superoxide (O2 )

Indexed keywords

CALMODULIN; CITRULLINE; CYCLIC GMP; NITRIC OXIDE SYNTHASE; SUPEROXIDE DISMUTASE; TYROSINE DERIVATIVE;

EID: 0029991827     PISSN: 08910618     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-0618(96)00137-8     Document Type: Conference Paper
Times cited : (149)

References (61)
  • 3
    • 0028584148 scopus 로고
    • Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration
    • Beckman, J.S., Chen, J., Crow, J.P. and Ye, Y.Z. (1994) Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration. Prog. Brain Res. 103, 371-380.
    • (1994) Prog. Brain Res. , vol.103 , pp. 371-380
    • Beckman, J.S.1    Chen, J.2    Crow, J.P.3    Ye, Y.Z.4
  • 4
    • 0028813380 scopus 로고
    • Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function
    • Borchelt, D.R., Guarnieri, M., Wong, P.C., Lee, M.K., Slunt, H.S., Xu, Z.S., Sisodia, S.S., Price, D.L. and Cleveland, D.W. (1995) Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. J. Biol. Chem. 270, 3234-3238.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3234-3238
    • Borchelt, D.R.1    Guarnieri, M.2    Wong, P.C.3    Lee, M.K.4    Slunt, H.S.5    Xu, Z.S.6    Sisodia, S.S.7    Price, D.L.8    Cleveland, D.W.9
  • 5
    • 0028960506 scopus 로고
    • Amyotrophic lateral sclerosis: Recent insights from genetics and transgenic mice
    • Brown, R.H. Jr. (1995) Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice. Cell 80, 687-692.
    • (1995) Cell , vol.80 , pp. 687-692
    • Brown R.H., Jr.1
  • 6
    • 0014336826 scopus 로고
    • Proximal axonal enlargement in motor neuron disease
    • Carpenter, S. (1968) Proximal axonal enlargement in motor neuron disease. Neurology. 18, 841-851.
    • (1968) Neurology , vol.18 , pp. 841-851
    • Carpenter, S.1
  • 7
    • 0003165970 scopus 로고
    • Pathognomy of intraneuronal inclusions in ALS
    • (eds Tsubaki, T. and Toyokura, Y.), University of Tokyo Press
    • Chou, S.M. (1979) Pathognomy of intraneuronal inclusions in ALS. In Amyotrophic Lateral Sclerosis (eds Tsubaki, T. and Toyokura, Y.), University of Tokyo Press, pp. 135-176.
    • (1979) Amyotrophic Lateral Sclerosis , pp. 135-176
    • Chou, S.M.1
  • 8
    • 0343801982 scopus 로고
    • Neuropathology of upper motor neurons in ALS
    • Chou, S.M. (1991) Neuropathology of upper motor neurons in ALS. In Proc XIth Int. Cong. Neuropathol., pp. 595-598.
    • (1991) Proc XIth Int. Cong. Neuropathol. , pp. 595-598
    • Chou, S.M.1
  • 9
    • 0343537855 scopus 로고
    • Accumulation of disassembled neurofilaments in upper motor neurons of amyotrophic lateral sclerosis
    • (ed Rose, F.C.), chapter 22. Smith-Gordon, London
    • Chou, S.M. (1994) Accumulation of disassembled neurofilaments in upper motor neurons of amyotrophic lateral sclerosis. In ALS -From Charcot to the Present and into the Future (ed Rose, F.C.), chapter 22. Smith-Gordon, London.
    • (1994) ALS -from Charcot to the Present and into the Future
    • Chou, S.M.1
  • 10
    • 0003049433 scopus 로고
    • Pathology of motor system disorders
    • (eds Leigh, N. and Swash, M.), chapter 4. Springer-Verlag, London
    • Chou, S.M. (1995) Pathology of motor system disorders. In Motor Neuron Disease: Biology and Management (eds Leigh, N. and Swash, M.), chapter 4. Springer-Verlag, London.
    • (1995) Motor Neuron Disease: Biology and Management
    • Chou, S.M.1
  • 12
    • 0029004898 scopus 로고
    • Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis
    • Collard, J.-F., Côté, F. and Julien, J.-P. (1995) Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis. Nature 375, 61-64.
    • (1995) Nature , vol.375 , pp. 61-64
    • Collard, J.-F.1    Côté, F.2    Julien, J.-P.3
  • 13
    • 0027465098 scopus 로고
    • Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
    • Côté, F., Collard, J.-F. and Julien, J.-P. (1993) Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell 73, 35-46.
    • (1993) Cell , vol.73 , pp. 35-46
    • Côté, F.1    Collard, J.-F.2    Julien, J.-P.3
  • 14
    • 0027946294 scopus 로고
    • Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
    • Del Canto, M.C. and Gurney, M.E. (1994) Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am. J. Pathol. 145, 1271-1280.
    • (1994) Am. J. Pathol. , vol.145 , pp. 1271-1280
    • Del Canto, M.C.1    Gurney, M.E.2
  • 15
    • 0027426169 scopus 로고
    • Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase
    • Deng, H.-X., Hentati, A., Tainer, J.A. et al. (1993) Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science 261, 1047-1051.
    • (1993) Science , vol.261 , pp. 1047-1051
    • Deng, H.-X.1    Hentati, A.2    Tainer, J.A.3
  • 16
    • 0028226788 scopus 로고
    • Nitric oxide synthase immunoreactivity in rat pontine medullary neurons
    • Dun, N.J., Dun, S.L. and Forstermann, U. (1994) Nitric oxide synthase immunoreactivity in rat pontine medullary neurons. Neuroscience 59, 429-445.
    • (1994) Neuroscience , vol.59 , pp. 429-445
    • Dun, N.J.1    Dun, S.L.2    Forstermann, U.3
  • 17
  • 18
    • 0026077959 scopus 로고
    • Glutamate, nitric oxide and cell-cell signaling in the nervous system
    • Garthwaite, J. (1991) Glutamate, nitric oxide and cell-cell signaling in the nervous system. Trends Neurosci. 14, 60-67.
    • (1991) Trends Neurosci. , vol.14 , pp. 60-67
    • Garthwaite, J.1
  • 19
    • 0028853371 scopus 로고
    • Neural nitric oxide signalling
    • Garthwaite, J. (1995) Neural nitric oxide signalling. Trends Neurosci. 18, 51-52.
    • (1995) Trends Neurosci. , vol.18 , pp. 51-52
    • Garthwaite, J.1
  • 20
    • 0021092750 scopus 로고
    • Neurofilament architecture combines structural principles of intermediate filaments with carboxyl-terminal extensions increasing in size between triplet proteins
    • Geisler, N., Kaufmann, E., Fischer, S., Plessman, U. and Weber, K. (1983) Neurofilament architecture combines structural principles of intermediate filaments with carboxyl-terminal extensions increasing in size between triplet proteins. EMBO 2, 1295-1302.
    • (1983) EMBO , vol.2 , pp. 1295-1302
    • Geisler, N.1    Kaufmann, E.2    Fischer, S.3    Plessman, U.4    Weber, K.5
  • 21
    • 0019888431 scopus 로고
    • Self assembly in vitro of the 68 000-mw component of the mammalian neurofilament triplet protein into intermediate sized filament
    • Geisler, N. and Weber, K. (1981) Self assembly in vitro of the 68 000-mw component of the mammalian neurofilament triplet protein into intermediate sized filament. J. Mol. Biol. 151, 565-571.
    • (1981) J. Mol. Biol. , vol.151 , pp. 565-571
    • Geisler, N.1    Weber, K.2
  • 22
    • 0027763184 scopus 로고
    • The rod domain of NF-L determines neurofilament architecture, whereas the end domains specify filament assembly and network formation
    • Heins, S., Wong, P.C., Muller, S., Goldie, K., Cleveland, D.W. and Aebi, U. (1993) The rod domain of NF-L determines neurofilament architecture, whereas the end domains specify filament assembly and network formation. J. Cell Biol. 123, 1517-1533.
    • (1993) J. Cell Biol. , vol.123 , pp. 1517-1533
    • Heins, S.1    Wong, P.C.2    Muller, S.3    Goldie, K.4    Cleveland, D.W.5    Aebi, U.6
  • 23
    • 0002671681 scopus 로고
    • Molecular architecture and dynamics of the neuronal cytoskeleton
    • (ed Burgoyne, R.D.), Wiley-Liss, New York
    • Hirokawa, N. (1991) Molecular architecture and dynamics of the neuronal cytoskeleton. In The Neuronal Cytoskeleton (ed Burgoyne, R.D.), pp. 5-74. Wiley-Liss, New York.
    • (1991) The Neuronal Cytoskeleton , pp. 5-74
    • Hirokawa, N.1
  • 24
    • 0015108227 scopus 로고
    • Ultrastructure of anterior horn motor neurons in the Hirano-Kurland-Sayre type of combined neurological system degeneration
    • Hughes, J.T. and Jerrome, D. (1971) Ultrastructure of anterior horn motor neurons in the Hirano-Kurland-Sayre type of combined neurological system degeneration. J. Neurol. Sci. 13, 389-399.
    • (1971) J. Neurol. Sci. , vol.13 , pp. 389-399
    • Hughes, J.T.1    Jerrome, D.2
  • 25
    • 0342496743 scopus 로고
    • Pathological changes of amyotrophic lateral sclerosis. An autopsy case of 10 months' duration
    • Tokyo
    • Inoue, K. and Hirano, A. (1979) Pathological changes of amyotrophic lateral sclerosis. An autopsy case of 10 months' duration. Neurol. Med. (Tokyo) 11, 448-455.
    • (1979) Neurol. Med. , vol.11 , pp. 448-455
    • Inoue, K.1    Hirano, A.2
  • 28
    • 0028116467 scopus 로고
    • A mutant neurofilament subunit causes massive, selective motor neuron death: Implication for the pathogenesis of human motor neuron disease
    • Lee, M.K., Marszalek, J.R. and Cleveland, D.W. (1994) A mutant neurofilament subunit causes massive, selective motor neuron death: implication for the pathogenesis of human motor neuron disease. Neuron 13, 975-988.
    • (1994) Neuron , vol.13 , pp. 975-988
    • Lee, M.K.1    Marszalek, J.R.2    Cleveland, D.W.3
  • 30
    • 0023709286 scopus 로고
    • Ubiquitin is a component of neurofibrillary tangles in a variety of neurodegenerative diseases
    • Lennox, G., Lowe, J., Morrell, K. et al. (1988) Ubiquitin is a component of neurofibrillary tangles in a variety of neurodegenerative diseases. Neurosci. Lett. 24, 211-217.
    • (1988) Neurosci. Lett. , vol.24 , pp. 211-217
    • Lennox, G.1    Lowe, J.2    Morrell, K.3
  • 31
    • 0023927981 scopus 로고
    • Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and Mallory bodies in alcoholic liver disease
    • Low, J., Blanchard, A., Morrell, K. et al. (1988) Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and Mallory bodies in alcoholic liver disease. J. Pathol. 155, 9-15.
    • (1988) J. Pathol. , vol.155 , pp. 9-15
    • Low, J.1    Blanchard, A.2    Morrell, K.3
  • 32
    • 0028096184 scopus 로고
    • Nitric oxide-dependent efflux of cGMP in rat cerebellar cortex: An in vivo microdialysis study
    • Luo, D., Leung, E. and Vincent, S.R. (1994) Nitric oxide-dependent efflux of cGMP in rat cerebellar cortex: an in vivo microdialysis study. J. Neurosci. 14, 263-271.
    • (1994) J. Neurosci. , vol.14 , pp. 263-271
    • Luo, D.1    Leung, E.2    Vincent, S.R.3
  • 33
    • 0028956596 scopus 로고
    • CNS distribution and overexpression of neurofilament light proteins (NF-L) in mice transgenic for the human NF-L: Aberrant accumulation in thalamic perikarya
    • Mathieu, J.F., Ma, D., Descarries, L., Vallee, A., Parent, A., Julien, J.P. and Doucet, G. (1995) CNS distribution and overexpression of neurofilament light proteins (NF-L) in mice transgenic for the human NF-L: aberrant accumulation in thalamic perikarya. Exp. Neurol. 132, 134-146.
    • (1995) Exp. Neurol. , vol.132 , pp. 134-146
    • Mathieu, J.F.1    Ma, D.2    Descarries, L.3    Vallee, A.4    Parent, A.5    Julien, J.P.6    Doucet, G.7
  • 34
    • 0025305245 scopus 로고
    • Chemical influences on the specificity of tyrosine phosphorylation
    • Martin, B.L., Wu, D., Jakes, S. and Graves, D.J. (1990) Chemical influences on the specificity of tyrosine phosphorylation. J. Biol. Chem. 265, 7108-7111.
    • (1990) J. Biol. Chem. , vol.265 , pp. 7108-7111
    • Martin, B.L.1    Wu, D.2    Jakes, S.3    Graves, D.J.4
  • 35
    • 0025063609 scopus 로고
    • Excitatory amino acid neurotoxicity and neurodegenerative disease
    • Meldrum, B.S. and Garthwaite, J. (1990) Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol. Sci. 11, 379-387.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 379-387
    • Meldrum, B.S.1    Garthwaite, J.2
  • 36
    • 0025214380 scopus 로고
    • Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis
    • Murayama, S., Mori, H., Ihara, Y., Bouldin, T.W., Suzuki, K. and Tomonaga, M. (1990) Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis. Ann. Neurol. 27, 137-148.
    • (1990) Ann. Neurol. , vol.27 , pp. 137-148
    • Murayama, S.1    Mori, H.2    Ihara, Y.3    Bouldin, T.W.4    Suzuki, K.5    Tomonaga, M.6
  • 37
    • 0027473029 scopus 로고
    • Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle
    • Nakane, M., Schmidt, H., Pollock, J.S., Förstermann, U. and Murad, F. (1993) Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle. FEBS 316, 175-180.
    • (1993) FEBS , vol.316 , pp. 175-180
    • Nakane, M.1    Schmidt, H.2    Pollock, J.S.3    Förstermann, U.4    Murad, F.5
  • 38
    • 0029015626 scopus 로고
    • Cu/Zn superoxide dismutase-like immunoreactivity is present in Lewy bodies from Parkinson disease: A light and electron microscopic immunocytochemical study
    • Nishiyama, K., Murayama, S., Shimizu, J., Ohya, Y. et al. (1995) Cu/Zn superoxide dismutase-like immunoreactivity is present in Lewy bodies from Parkinson disease: a light and electron microscopic immunocytochemical study. Acta. Neuropathol. 89, 471-474.
    • (1995) Acta. Neuropathol. , vol.89 , pp. 471-474
    • Nishiyama, K.1    Murayama, S.2    Shimizu, J.3    Ohya, Y.4
  • 39
    • 0027531842 scopus 로고
    • The regulation of neurofilament protein dynamics by phosphorylation: Clues to neurofibrillary pathology
    • Nixon, R.A. (1993) The regulation of neurofilament protein dynamics by phosphorylation: clues to neurofibrillary pathology. Brain Pathol. 3, 29-38.
    • (1993) Brain Pathol. , vol.3 , pp. 29-38
    • Nixon, R.A.1
  • 40
    • 0028815433 scopus 로고
    • Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons
    • Pardo, C.A., Xu, Z., Borchelt, D.R., Price, D., Sisodia, S. and Cleveland, D.W. (1995) Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc. Natl. Acad. Sci. USA 92, 954-958.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 954-958
    • Pardo, C.A.1    Xu, Z.2    Borchelt, D.R.3    Price, D.4    Sisodia, S.5    Cleveland, D.W.6
  • 41
    • 0025856774 scopus 로고
    • Citrulline in the rat brain: Immunohistochemistry and coexistence with NADPH-diaphorase
    • Pasquaolotto, B.A., Hope, B.T. and Vincent, S.R. (1991) Citrulline in the rat brain: immunohistochemistry and coexistence with NADPH-diaphorase. Neurosci. Lett. 128, 155-160.
    • (1991) Neurosci. Lett. , vol.128 , pp. 155-160
    • Pasquaolotto, B.A.1    Hope, B.T.2    Vincent, S.R.3
  • 44
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen, D.R. et al. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62.
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1
  • 46
    • 0028899301 scopus 로고
    • Amyotrophic lateral sclerosis: Human challenge for neuroscience
    • Rowland, L.P. (1995) Amyotrophic lateral sclerosis: human challenge for neuroscience. Proc. Natl. Soc. Sci. USA 92, 1251-1253.
    • (1995) Proc. Natl. Soc. Sci. USA , vol.92 , pp. 1251-1253
    • Rowland, L.P.1
  • 48
    • 0023786805 scopus 로고
    • Swelling of neuronal processes in motor neuron disease
    • Sasaki, S., Kamei, H., Yamane, K. and Murayama, S. (1992) Swelling of neuronal processes in motor neuron disease. Neurology 38, 1114-1118.
    • (1992) Neurology , vol.38 , pp. 1114-1118
    • Sasaki, S.1    Kamei, H.2    Yamane, K.3    Murayama, S.4
  • 49
    • 0024373326 scopus 로고
    • Swelling of the proximal axons in a case of motor neuron disease
    • Sasaki, S., Maruyama, S. and Yamane, K. (1989). Swelling of the proximal axons in a case of motor neuron disease. Ann. Neurol. 25, 520-522.
    • (1989) Ann. Neurol. , vol.25 , pp. 520-522
    • Sasaki, S.1    Maruyama, S.2    Yamane, K.3
  • 50
    • 0029014792 scopus 로고
    • Distribution of nitric oxide synthase in the central nervous system of Macaca fuscata: Subcortical regions
    • Satoh, K., Arai, R., Ikemoto, K., Narita, M., Nagai, T., Ohshima, H. and Kitahama, K. (1995) Distribution of nitric oxide synthase in the central nervous system of Macaca fuscata: subcortical regions. Neuroscience 66, 685-696.
    • (1995) Neuroscience , vol.66 , pp. 685-696
    • Satoh, K.1    Arai, R.2    Ikemoto, K.3    Narita, M.4    Nagai, T.5    Ohshima, H.6    Kitahama, K.7
  • 51
    • 85015902212 scopus 로고
    • Immunohistochemical demonstration of Cu/Zn superoxide dismutase in the spinal cord of patients with familial amyotrophic lateral sclerosis
    • Shibata, N., Hirano, M., and Kobayashi, K. (1993) Immunohistochemical demonstration of Cu/Zn superoxide dismutase in the spinal cord of patients with familial amyotrophic lateral sclerosis. Acta. Histochem. Cytochem. 26, 619-621.
    • (1993) Acta. Histochem. Cytochem. , vol.26 , pp. 619-621
    • Shibata, N.1    Hirano, M.2    Kobayashi, K.3
  • 52
    • 0027966078 scopus 로고
    • Cu/Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis
    • Shibata, N., Hirano, A., Kobayashi, K. et al. (1994) Cu/Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis. Neurosci. Lett. 179, 149-152.
    • (1994) Neurosci. Lett. , vol.179 , pp. 149-152
    • Shibata, N.1    Hirano, A.2    Kobayashi, K.3
  • 53
    • 0014516558 scopus 로고
    • Intraneuronal conglomerates in sporadic motor neuron disease
    • Chic
    • Schochet, S.S. Jr, Hardman, J.M., Ladewig, P.P. and Earle, K.M. (1969) Intraneuronal conglomerates in sporadic motor neuron disease. Arch. Neurol. (Chic) 20, 548-553.
    • (1969) Arch. Neurol. , vol.20 , pp. 548-553
    • Schochet S.S., Jr.1    Hardman, J.M.2    Ladewig, P.P.3    Earle, K.M.4
  • 54
    • 0027384515 scopus 로고
    • The nitric oxide-cyclic GMP signalling
    • Southam, E. and Garthwaite, J. (1993) The nitric oxide-cyclic GMP signalling. Neuropharmacology 32, 1267-1277.
    • (1993) Neuropharmacology , vol.32 , pp. 1267-1277
    • Southam, E.1    Garthwaite, J.2
  • 55
    • 0027219352 scopus 로고
    • Coexistence of NADPH diaphorase with GABA, glycine, and acetylcholine in rat spinal cord
    • Spike, R.C., Todd, A.J. and Johnson, H.M. (1993) Coexistence of NADPH diaphorase with GABA, glycine, and acetylcholine in rat spinal cord. J. Comp. Neurol. 335, 320-333.
    • (1993) J. Comp. Neurol. , vol.335 , pp. 320-333
    • Spike, R.C.1    Todd, A.J.2    Johnson, H.M.3
  • 56
    • 0026452101 scopus 로고
    • Neurofilament and glial alterations in the cerebral cortex in amyotrophic lateral sclerosis
    • Troost, D., Sillevis Smitt, P.A.E., de Jong, J.M.B. and Swaab, D.F. (1992) Neurofilament and glial alterations in the cerebral cortex in amyotrophic lateral sclerosis. Acta. Neuropathol. 84, 664-673.
    • (1992) Acta. Neuropathol. , vol.84 , pp. 664-673
    • Troost, D.1    Sillevis Smitt, P.A.E.2    De Jong, J.M.B.3    Swaab, D.F.4
  • 57
    • 0343365393 scopus 로고
    • Histochemistry of the neuronal nitric oxide system
    • Vincent, S.R. (1993). Histochemistry of the neuronal nitric oxide system. J. Histochem. Cytochem. 41, 1126.
    • (1993) J. Histochem. Cytochem. , vol.41 , pp. 1126
    • Vincent, S.R.1
  • 58
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong, P.C., Pardo, C.A., Borchelt, D.R., Lee, M.K., Copeland, N.G., Jenkins, N.A., Sisodia, S.S., Cleveland, D.W. and Price, D.L. (1995) An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14, 1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9
  • 59
    • 0027157901 scopus 로고
    • Inhibition of nitric oxide synthase reduces motor neuron death due to spinal root avulsion
    • Wu, W. and Li, L. (1993) Inhibition of nitric oxide synthase reduces motor neuron death due to spinal root avulsion. Neurosci. Lett. 153, 121-124.
    • (1993) Neurosci. Lett. , vol.153 , pp. 121-124
    • Wu, W.1    Li, L.2
  • 60
    • 0028324027 scopus 로고
    • Nitric oxide synthase in motor neurons after axotomy
    • Yu, W.-H.A. (1994) Nitric oxide synthase in motor neurons after axotomy. J. Histochem. Cytochem. 42, 451-457.
    • (1994) J. Histochem. Cytochem. , vol.42 , pp. 451-457
    • Yu, W.-H.A.1
  • 61
    • 0027410516 scopus 로고
    • Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
    • Xu, Z., Cork, L., Griffin, J.W. and Cleveland, D.W. (1993) Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73, 23-33.
    • (1993) Cell , vol.73 , pp. 23-33
    • Xu, Z.1    Cork, L.2    Griffin, J.W.3    Cleveland, D.W.4


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