-
1
-
-
0000280462
-
Deux cas d'atrophie musculaire progressive avec lesions de la substance grise et des faisceaux antero-lateraux de la moelle epiniere
-
Charcot, J. M. & Joffory, A. Deux cas d'atrophie musculaire progressive avec lesions de la substance grise et des faisceaux antero-lateraux de la moelle epiniere. Arch. Physiol. Weurol. Pathol. 2, 744-754 (1869).
-
(1869)
Arch. Physiol. Weurol. Pathol.
, vol.2
, pp. 744-754
-
-
Charcot, J.M.1
Joffory, A.2
-
2
-
-
0023000254
-
Follow-up study on amyotrophic lateral sclerosis in Rochester, Minn., 1925 through 1984
-
Yoshida, S., Mulder, D. W., Kurland, L. T., Chu, C. P & Okazaki, H. Follow-up study on amyotrophic lateral sclerosis in Rochester, Minn., 1925 through 1984. Weuroepidemiology 5, 61-70 (1986).
-
(1986)
Weuroepidemiology
, vol.5
, pp. 61-70
-
-
Yoshida, S.1
Mulder, D.W.2
Kurland, L.T.3
Chu, C.P.4
Okazaki, H.5
-
3
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D. R. et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Wature 362, 59-62 (1993).
-
(1993)
Wature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
-
4
-
-
0021167918
-
Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis
-
Hirano, A., Donnenfeld, H., Sasaki, S. & Nakano, I. Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis. J. Weuropathol. Exp. Weurol. 43, 461-470 (1984).
-
(1984)
J. Weuropathol. Exp. Weurol.
, vol.43
, pp. 461-470
-
-
Hirano, A.1
Donnenfeld, H.2
Sasaki, S.3
Nakano, I.4
-
5
-
-
0021157469
-
Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis
-
Hirano, A. et al. Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis. J. Weuropathol. Exp. Weurol. 43, 471-480 (1984).
-
(1984)
J. Weuropathol. Exp. Weurol.
, vol.43
, pp. 471-480
-
-
Hirano, A.1
-
6
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
Bruijn, L. I. et al. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science 281, 1851-1854 (1998).
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijn, L.I.1
-
7
-
-
0022443737
-
Familial adult motor neuron disease: Amyotrophic lateral sclerosis
-
Mulder, D. W., Kurland, L. T., Offord, K. P. & Beard, C. M. Familial adult motor neuron disease: amyotrophic lateral sclerosis. Neurology 36, 511-517 (1986).
-
(1986)
Neurology
, vol.36
, pp. 511-517
-
-
Mulder, D.W.1
Kurland, L.T.2
Offord, K.P.3
Beard, C.M.4
-
8
-
-
15844429977
-
Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo
-
Longo, V. D., Gralla, E. B. & Valentine, J. S. Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo. J. Biol. Chem. 271, 12275-12280 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12275-12280
-
-
Longo, V.D.1
Gralla, E.B.2
Valentine, J.S.3
-
9
-
-
0347233829
-
-
(eds Brown, R. H., Meininger, V & Swash, M., Martin Dunitz, London
-
Andersen, P M., Morita, M. & Brown, R. H. Jr. in Amyotrophic Lateral Sclerosis (eds Brown, R. H., Meininger, V & Swash, M.) 223-250 (Martin Dunitz, London, 2000).
-
(2000)
Amyotrophic Lateral Sclerosis
, pp. 223-250
-
-
Andersen, P.M.1
Morita, M.2
Brown, R.H.3
-
10
-
-
79961149073
-
Current status of SOD1 mutations in familial amyotrophic lateral sclerosis
-
Gaudette, M., Hirano, M. & Siddique, T. Current status of SOD1 mutations in familial amyotrophic lateral sclerosis. Amyotroph. Lateral Scler. Other Motor Weuron Disord. 1, 83-89 (2000).
-
(2000)
Amyotroph. Lateral Scler. Other Motor Weuron Disord.
, vol.1
, pp. 83-89
-
-
Gaudette, M.1
Hirano, M.2
Siddique, T.3
-
12
-
-
0029010496
-
Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase
-
Andersen, P M. et al. Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase. Wature Genet. 10, 61-66 (1995).
-
(1995)
Wature Genet
, vol.10
, pp. 61-66
-
-
Andersen, P.M.1
-
13
-
-
9544236295
-
Autosomal recessive adult-onset amyotrophic lateral sclerosis associated with homozygosity for Asp90Ala CuZn-superoxide dismutase mutation. A clinical and genealogical study of 36 patients
-
Andersen, P M. et al. Autosomal recessive adult-onset amyotrophic lateral sclerosis associated with homozygosity for Asp90Ala CuZn-superoxide dismutase mutation. A clinical and genealogical study of 36 patients. Brain 119, 1153-1172 (1996).
-
(1996)
Brain
, vol.119
, pp. 1153-1172
-
-
Andersen, P.M.1
-
14
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase
-
Deng, H. X. et al. Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science 261, 1047-1051 (1993).
-
(1993)
Science
, vol.261
, pp. 1047-1051
-
-
Deng, H.X.1
-
15
-
-
0028941313
-
A novel SOD mutant and ALS
-
Orrell, R., De Belleroche, J., Marklund, S., Bowe, F. & Hallewell, R. A novel SOD mutant and ALS. Wature 374, 504-505 (1995).
-
(1995)
Wature
, vol.374
, pp. 504-505
-
-
Orrell, R.1
De Belleroche, J.2
Marklund, S.3
Bowe, F.4
Hallewell, R.5
-
16
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
-
Gurney, M. E. et al. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 264, 1772-1775 (1994).
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
-
17
-
-
0029053881
-
An adverse property of a familial ALS- linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
Wong, P C. et al. An adverse property of a familial ALS- linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Weuron 14, 1105-1116 (1995).
-
(1995)
Weuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
-
18
-
-
0028888945
-
Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
-
Ripps, M. E., Huntley, G. W., Hof, P R., Morrison, J. H. & Gordon, J. W. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc. WatlAcad. Sci. USA 92, 689-693 (1995).
-
(1995)
Proc. Watlacad. Sci. USA
, vol.92
, pp. 689-693
-
-
Ripps, M.E.1
Huntley, G.W.2
Hof, P.R.3
Morrison, J.H.4
Gordon, J.W.5
-
19
-
-
0031051485
-
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
-
Bruijn, L. I. et al. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Weuron 18, 327-338 (1997).
-
(1997)
Weuron
, vol.18
, pp. 327-338
-
-
Bruijn, L.I.1
-
20
-
-
15844393658
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
Reaume, A. G. et al. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Wature Genet. 13, 43-47 (1996).
-
(1996)
Wature Genet
, vol.13
, pp. 43-47
-
-
Reaume, A.G.1
-
21
-
-
0027965073
-
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity
-
Borchelt, D. R. et al. Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proc. Watl Acad. Sci. USA 91, 8292-8296 (1994).
-
(1994)
Proc. Watl Acad. Sci. USA
, vol.91
, pp. 8292-8296
-
-
Borchelt, D.R.1
-
22
-
-
0028940996
-
Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis
-
Bowling, A. C. et al. Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis. J. Weurochem. 64, 2366-2369 (1995).
-
(1995)
J. Weurochem.
, vol.64
, pp. 2366-2369
-
-
Bowling, A.C.1
-
23
-
-
0028811152
-
Toxic mutants in Charcot's sclerosis
-
Cleveland, D. W., Laing, N., Hurse, P. V & Brown, R. H. Jr. Toxic mutants in Charcot's sclerosis. Wature 378, 342-343 (1995).
-
(1995)
Wature
, vol.378
, pp. 342-343
-
-
Cleveland, D.W.1
Laing, N.2
Hurse, P.V.3
Brown, R.H.4
-
24
-
-
0030756459
-
Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Kostic, V, Jackson-Lewis, V, De Bilbao, F., Dubois- Dauphin, M. & Przedborski, S. Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science 277, 559-562 (1997).
-
(1997)
Science
, vol.277
, pp. 559-562
-
-
Kostic, V.1
Jackson-Lewis, V.2
De Bilbao, F.3
Dubois-Dauphin, M.4
Przedborski, S.5
-
25
-
-
0034671376
-
Delaying caspase activation by Bcl-2: A clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis
-
Vukosavic, S. et al. Delaying caspase activation by Bcl-2: a clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis. J. Weurosci. 20, 9119-9125 (2000).
-
(2000)
J. Weurosci.
, vol.20
, pp. 9119-9125
-
-
Vukosavic, S.1
-
26
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
Li, M. et al. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 288, 335-339 (2000).
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
-
27
-
-
0034610328
-
Caspase-1 and -3 are sequentially activated in motor neuron death in Cu, Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis
-
Pasinelli, P., Houseweart, M. K., Brown, R. H. Jr & Cleveland, D. W. Caspase-1 and -3 are sequentially activated in motor neuron death in Cu, Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis. Proc. Watl Acad. Sci. USA 97, 13901-13906 (2000).
-
(2000)
Proc. Watl Acad. Sci. USA
, vol.97
, pp. 13901-13906
-
-
Pasinelli, P.1
Houseweart, M.K.2
Brown, R.H.3
Cleveland, D.W.4
-
28
-
-
0035437866
-
Recruitment of the mitochondrial- dependent apoptotic pathway in amyotrophic lateral sclerosis
-
Guegan, C., Vila, M., Rosoklija, G., Hays, A. P & Przedborski, S. Recruitment of the mitochondrial- dependent apoptotic pathway in amyotrophic lateral sclerosis. J. Weurosci. 21, 6569-6576 (2001).
-
(2001)
J. Weurosci.
, vol.21
, pp. 6569-6576
-
-
Guegan, C.1
Vila, M.2
Rosoklija, G.3
Hays, A.P.4
Przedborski, S.5
-
29
-
-
0032568546
-
Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis- linked superoxide dismutase mutants
-
Corson, L. B., Strain, J. J., Culotta, V C. & Cleveland, D. W. Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis- linked superoxide dismutase mutants. Proc. Watl Acad. Sci. USA 95, 6361-6366 (1998).
-
(1998)
Proc. Watl Acad. Sci. USA
, vol.95
, pp. 6361-6366
-
-
Corson, L.B.1
Strain, J.J.2
Culotta, V.C.3
Cleveland, D.W.4
-
30
-
-
0027293275
-
SOD and peroxynitrite
-
Beckman, J. S., Carson, M., Smith, C. D. & Koppenol, W. H. ALS, SOD and peroxynitrite. Wature 364, 584 (1993).
-
(1993)
Wature
, vol.364
, pp. 584
-
-
Beckman, J.S.1
Carson, M.2
Smith, C.D.3
Koppenol, W.4
-
31
-
-
0030767498
-
Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation
-
Ferrante, R. J. et al. Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation. Ann. Weurol. 42, 326-334 (1997).
-
(1997)
Ann. Weurol.
, vol.42
, pp. 326-334
-
-
Ferrante, R.J.1
-
32
-
-
0030806228
-
Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant
-
Bruijn, L. I. et al. Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant. Proc. Watl Acad. Sci. USA 94, 7606-7611 (1997).
-
(1997)
Proc. Watl Acad. Sci. USA 94
, pp. 7606-7611
-
-
Bruijn, L.I.1
-
33
-
-
0031784348
-
Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Andrus, P K., Fleck, T J., Gurney, M. E. & Hall, E. D. Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis. J. Weurochem. 71, 2041-2048 (1998).
-
(1998)
J. Weurochem.
, vol.71
, pp. 2041-2048
-
-
Andrus, P.K.1
Fleck, T.J.2
Gurney, M.E.3
Hall, E.D.4
-
34
-
-
0030851761
-
Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis
-
Beal, M. F. et al. Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Ann. Weurol. 42, 644-654 (1997).
-
(1997)
Ann. Weurol.
, vol.42
, pp. 644-654
-
-
Beal, M.F.1
-
35
-
-
0034520591
-
Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1
-
Jaarsma, D. et al. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1. Weurobiol. Dis. 7, 623-643 (2000).
-
(2000)
Weurobiol. Dis.
, vol.7
, pp. 623-643
-
-
Jaarsma, D.1
-
36
-
-
0029671220
-
Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis
-
Wiedau-Pazos, M. et al. Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science 271, 515-518 (1996).
-
(1996)
Science
, vol.271
, pp. 515-518
-
-
Wiedau-Pazos, M.1
-
37
-
-
0032499788
-
Reexamination of the mechanism of hydroxyl radical adducts formed from the reaction between familial amyotrophic lateral sclerosis-associated Cu, Zn superoxide dismutase mutants and H2O2
-
2. Proc. Watl Acad. Sci. USA 95, 6675-6680 (1998).
-
(1998)
Proc. Watl Acad. Sci. USA
, vol.95
, pp. 6675-6680
-
-
Singh, R.J.1
-
38
-
-
0032127330
-
Relationship of oxygen radical-induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS
-
Hall, E. D., Andrus, P. K., Oostveen, J. A., Fleck, T J. & Gurney, M. E. Relationship of oxygen radical-induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS. J. Weurosci. Res. 53, 66-77 (1998).
-
(1998)
J. Weurosci. Res.
, vol.53
, pp. 66-77
-
-
Hall, E.D.1
Rus, P.K.2
Oostveen, J.A.3
Fleck, T.J.4
Gurney, M.E.5
-
39
-
-
0028813380
-
Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function
-
Borchelt, D. R. et al. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. J. Biol. Chem. 270, 3234-3238 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3234-3238
-
-
Borchelt, D.R.1
-
40
-
-
0030833449
-
Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite
-
Crow, J. P, Sampson, J. B., Zhuang, Y, Thompson, J. A. & Beckman, J. S. Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite. J. Weurochem. 69, 1936-1944 (1997).
-
(1997)
J. Weurochem.
, vol.69
, pp. 1936-1944
-
-
Crow, J.P.1
Sampson, J.B.2
Zhuang, Y.3
Thompson, J.A.4
Beckman, J.S.5
-
41
-
-
0039251419
-
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase
-
Estevez, A. G. et al. Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. Science 286, 2498-2500 (1999).
-
(1999)
Science
, vol.286
, pp. 2498-2500
-
-
Estevez, A.G.1
-
42
-
-
0034696741
-
Toxicity of ALS-linked SOD1 mutants
-
Williamson, T. L. et al. Toxicity of ALS-linked SOD1 mutants. Science 288, 399-400 (2000).
-
(2000)
Science
, vol.288
, pp. 399-400
-
-
Williamson, T.L.1
-
43
-
-
0033977325
-
Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis
-
Goto, J. J. et al. Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis. J. Biol. Chem. 275, 1007-1014 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1007-1014
-
-
Goto, J.J.1
-
44
-
-
0032954386
-
Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Facchinetti, F. et al. Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis. Weuroscience 90, 1483-1492 (1999).
-
(1999)
Weuroscience
, vol.90
, pp. 1483-1492
-
-
Facchinetti, F.1
-
45
-
-
0035826750
-
Nitrotyrosination contributes minimally to toxicity of mutant SOD1 associated with ALS
-
Doroudchi, M. M., Minotti, S., Figlewicz, D. A. & Durham, H. D. Nitrotyrosination contributes minimally to toxicity of mutant SOD1 associated with ALS. Weuroreport 12, 1239-1243 (2001).
-
(2001)
Weuroreport
, vol.12
, pp. 1239-1243
-
-
Doroudchi, M.M.1
Minotti, S.2
Figlewicz, D.A.3
Durham, H.D.4
-
46
-
-
0029082389
-
Oxidative damage to protein in sporadic motor neuron disease spinal cord
-
Shaw, P J., Ince, P. G., Falkous, G. & Mantle, D. Oxidative damage to protein in sporadic motor neuron disease spinal cord. Ann. Weurol. 38, 691-695 (1995).
-
(1995)
Ann. Weurol.
, vol.38
, pp. 691-695
-
-
Shaw, P.J.1
Ince, P.G.2
Falkous, G.3
Mantle, D.4
-
47
-
-
0027359334
-
Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
-
Bowling, A. C., Schulz, J. B., Brown, R. H. Jr & Beal, M. F. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J. Weurochem. 61, 2322-2325 (1993).
-
(1993)
J. Weurochem.
, vol.61
, pp. 2322-2325
-
-
Bowling, A.C.1
Schulz, J.B.2
Brown, R.H.3
Beal, M.F.4
-
48
-
-
0027946294
-
Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
-
Dal Canto, M. C. & Gurney, M. E. Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am. J. Pathol. 145, 1271-1279 (1994).
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1271-1279
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
49
-
-
0032079517
-
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
-
Kong, J. & Xu, Z. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J. Weurosci. 18, 3241-3250 (1998).
-
(1998)
J. Weurosci.
, vol.18
, pp. 3241-3250
-
-
Kong, J.1
Xu, Z.2
-
50
-
-
0030802648
-
The copper chaperone for superoxide dismutase
-
Culotta, V. C. et al. The copper chaperone for superoxide dismutase. J. Biol. Chem. 272, 23469-23472 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23469-23472
-
-
Culotta, V.C.1
-
51
-
-
0034646410
-
Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase
-
Wong, P. C. et al. Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase. Proc. Watl Acad. Sci. USA 97, 2886-2891 (2000).
-
(2000)
Proc. Watl Acad. Sci. USA
, vol.97
, pp. 2886-2891
-
-
Wong, P.C.1
-
52
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
Ferrante, R. J. et al. Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J. Weurochem. 69, 2064-2074 (1997).
-
(1997)
J. Weurochem.
, vol.69
, pp. 2064-2074
-
-
Ferrante, R.J.1
-
53
-
-
0033749379
-
Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
-
Johnston, J. A., Dalton, M. J., Gurney, M. E. & Kopito, R. R. Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. Proc. Watl Acad. Sci. USA 97, 12571-12576 (2000).
-
(2000)
Proc. Watl Acad. Sci. USA
, vol.97
, pp. 12571-12576
-
-
Johnston, J.A.1
Dalton, M.J.2
Gurney, M.E.3
Kopito, R.R.4
-
54
-
-
0027190478
-
Histochemical and immunocytochemical study of ubiquitinated neuronal inclusions in amyotrophic lateral sclerosis
-
Mather, K. et al. Histochemical and immunocytochemical study of ubiquitinated neuronal inclusions in amyotrophic lateral sclerosis. Weuropathol.Appl. Weurobiol. 19, 141-145 (1993).
-
(1993)
Weuropathol.Appl. Weurobiol.
, vol.19
, pp. 141-145
-
-
Mather, K.1
-
55
-
-
0025729489
-
Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity
-
Leigh, P N. et al. Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity. Brain 114, 775-788 (1991).
-
(1991)
Brain
, vol.114
, pp. 775-788
-
-
Leigh, P.N.1
-
56
-
-
0023823645
-
Ubiquitin deposits in anterior horn cells in motor neurone disease
-
Leigh, P N. et al. Ubiquitin deposits in anterior horn cells in motor neurone disease. Weurosci. Lett. 93, 197-203 (1988).
-
(1988)
Weurosci. Lett.
, vol.93
, pp. 197-203
-
-
Leigh, P.N.1
-
57
-
-
0344507132
-
Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn- superoxide dismutase mutants associated with amyotrophic lateral sclerosis
-
Bruening, W. et al. Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn- superoxide dismutase mutants associated with amyotrophic lateral sclerosis. J. Weurochem. 72, 693-699 (1999).
-
(1999)
J. Weurochem.
, vol.72
, pp. 693-699
-
-
Bruening, W.1
-
58
-
-
0030777650
-
Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS
-
Durham, H. D., Roy, J., Dong, L. & Figlewicz, D. A. Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS. J. Weuropathol. Exp. Weurol. 56, 523-530 (1997).
-
(1997)
J. Weuropathol. Exp. Weurol.
, vol.56
, pp. 523-530
-
-
Durham, H.D.1
Roy, J.2
Dong, L.3
Figlewicz, D.A.4
-
59
-
-
13344286293
-
Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
-
Rothstein, J. D. et al. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Weuron 16, 675-686 (1996).
-
(1996)
Weuron
, vol.16
, pp. 675-686
-
-
Rothstein, J.D.1
-
60
-
-
0034651102
-
Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration
-
Gong, Y. H., Parsadanian, A. S., Andreeva, A., Snider, W. D. & Elliott, J. L. Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration. J. Weurosci. 20, 660-665 (2000).
-
(2000)
J. Weurosci.
, vol.20
, pp. 660-665
-
-
Gong, Y.H.1
Parsadanian, A.S.2
Reeva, A.3
Snider, W.D.4
Elliott, J.L.5
-
61
-
-
0032482976
-
Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis- linked superoxide dismutase 1 mutant
-
Williamson, T. L. et al. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis- linked superoxide dismutase 1 mutant. Proc. Watl Acad. Sci. USA 95, 9631-9636 (1998).
-
(1998)
Proc. Watl Acad. Sci. USA
, vol.95
, pp. 9631-9636
-
-
Williamson, T.L.1
-
62
-
-
0032483016
-
Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase
-
Couillard-Despres, S. et al. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proc. Watl Acad. Sci. USA 95, 9626-9630 (1998).
-
(1998)
Proc. Watl Acad. Sci. USA
, vol.95
, pp. 9626-9630
-
-
Couillard-Despres, S.1
-
63
-
-
0035873076
-
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
-
Pramatarova, A., Laganiere, J., Roussel, J., Brisebois, K. & Rouleau, G. A. Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J. Weurosci. 21, 3369-3374 (2001).
-
(2001)
J. Weurosci.
, vol.21
, pp. 3369-3374
-
-
Pramatarova, A.1
Laganiere, J.2
Roussel, J.3
Brisebois, K.4
Rouleau, G.A.5
-
64
-
-
0014336826
-
Proximal axonal enlargement in motor neuron disease
-
Carpenter, S. Proximal axonal enlargement in motor neuron disease. Weurology 18, 841-851 (1968).
-
(1968)
Weurology
, vol.18
, pp. 841-851
-
-
Carpenter, S.1
-
65
-
-
0027410516
-
Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
-
Xu, Z., Cork, L. C., Griffin, J. W. & Cleveland, D. W. Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73, 23-33 (1993).
-
(1993)
Cell
, vol.73
, pp. 23-33
-
-
Xu, Z.1
Cork, L.C.2
Griffin, J.W.3
Cleveland, D.W.4
-
66
-
-
0027465098
-
P Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
-
Cote, F., Collard, J. F. & Julien, J. P Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell 73, 35-46 (1993).
-
(1993)
Cell
, vol.73
, pp. 35-46
-
-
Cote, F.1
Collard, J.F.2
Julien, J.3
-
67
-
-
0033830020
-
Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu, Zn superoxide dismutase
-
Couillard-Despres, S., Meier, J. & Julien, J. P. Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu, Zn superoxide dismutase. Weurobiol. Dis. 7, 462-470 (2000).
-
(2000)
Weurobiol. Dis.
, vol.7
, pp. 462-470
-
-
Couillard-Despres, S.1
Meier, J.2
Julien, J.P.3
-
68
-
-
17744368458
-
Deregulation of Cdk5 in a mouse model of ALS: Toxicity alleviated by perikaryal neurofilament inclusions
-
Nguyen, M. D., Lariviere, R. C. & Julien, J. P. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Weuron 30, 135-147 (2001).
-
(2001)
Weuron
, vol.30
, pp. 135-147
-
-
Nguyen, M.D.1
Lariviere, R.C.2
Julien, J.P.3
-
69
-
-
0033953140
-
Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis
-
Kong, J. & Xu, Z. Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis. Weurosci. Lett. 281, 72-74 (2000).
-
(2000)
Weurosci. Lett.
, vol.281
, pp. 72-74
-
-
Kong, J.1
Xu, Z.2
-
70
-
-
0033366384
-
Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
-
Williamson, T L. & Cleveland, D. W. Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Wature Weurosci. 2, 50-56 (1999).
-
(1999)
Wature Weurosci
, vol.2
, pp. 50-56
-
-
Williamson, T.L.1
Cleveland, D.W.2
-
71
-
-
0021087687
-
Modulations of neurofilament axonal transport during the development of rabbit retinal ganglion cells
-
Willard, M. & Simon, C. Modulations of neurofilament axonal transport during the development of rabbit retinal ganglion cells. Cell 35, 551-559 (1983).
-
(1983)
Cell
, vol.35
, pp. 551-559
-
-
Willard, M.1
Simon, C.2
-
72
-
-
0032926368
-
Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis
-
Al-Chalabi, A. et al. Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis. Hum. Mol. Genet. 8, 157-164 (1999).
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 157-164
-
-
Al-Chalabi, A.1
-
73
-
-
0028001606
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
-
Figlewicz, D. A. et al. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum. Mol. Genet. 3, 1757-1761 (1994).
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1757-1761
-
-
Figlewicz, D.A.1
-
74
-
-
0032427646
-
Novel insertion in the KSP region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS)
-
Tomkins, J. et al. Novel insertion in the KSP region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS). Weuroreport 9, 3967-3970 (1998).
-
(1998)
Weuroreport
, vol.9
, pp. 3967-3970
-
-
Tomkins, J.1
-
75
-
-
0035136847
-
Further evidence that neurofilament light chain gene mutations can cause Charcot-Marie-Tooth disease type 2E
-
De Jonghe, P. et al. Further evidence that neurofilament light chain gene mutations can cause Charcot-Marie-Tooth disease type 2E. Ann. Weurol. 49, 245-249 (2001).
-
(2001)
Ann. Weurol.
, vol.49
, pp. 245-249
-
-
De Jonghe, P.1
-
76
-
-
0033911099
-
A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene
-
Mersiyanova, I. V. et al. A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene. Am. J. Hum. Genet. 67, 37-46 (2000).
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 37-46
-
-
Mersiyanova, I.V.1
-
77
-
-
0029894157
-
Subunit composition of neurofilaments specifies axonal diameter
-
Xu, Z. et al. Subunit composition of neurofilaments specifies axonal diameter. J. Cell Biol. 133, 1061-1069 (1996).
-
(1996)
J. Cell Biol.
, vol.133
, pp. 1061-1069
-
-
Xu, Z.1
-
78
-
-
0019784990
-
Morphometric comparison of the vulnerability of peripheral motor and sensory neurons in amyotrophic lateral sclerosis
-
Kawamura, Y. et al. Morphometric comparison of the vulnerability of peripheral motor and sensory neurons in amyotrophic lateral sclerosis. J. Weuropathol. Exp. Weurol. 40, 667-675 (1981).
-
(1981)
J. Weuropathol. Exp. Weurol.
, vol.40
, pp. 667-675
-
-
Kawamura, Y.1
-
79
-
-
0028116467
-
A mutant neurofilament subunit causes massive, selective motor neuron death: Implications for the pathogenesis of human motor neuron disease
-
Lee, M. K., Marszalek, J. R. & Cleveland, D. W. A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease. Weuron 13, 975-988 (1994).
-
(1994)
Weuron
, vol.13
, pp. 975-988
-
-
Lee, M.K.1
Marszalek, J.R.2
Cleveland, D.W.3
-
80
-
-
0030812843
-
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1
-
Tanaka, K. et al. Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science 276, 1699-1702 (1997).
-
(1997)
Science
, vol.276
, pp. 1699-1702
-
-
Tanaka, K.1
-
81
-
-
0025873777
-
Excitatory amino acids in amyotrophic lateral sclerosis: An update
-
Rothstein, J. D. et al. Excitatory amino acids in amyotrophic lateral sclerosis: an update. Ann. Weurol. 30, 224-225 (1991).
-
(1991)
Ann. Weurol.
, vol.30
, pp. 224-225
-
-
Rothstein, J.D.1
-
82
-
-
0025299819
-
Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis
-
Rothstein, J. D. et al. Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis. Ann. Weurol. 28, 18-25 (1990).
-
(1990)
Ann. Weurol.
, vol.28
, pp. 18-25
-
-
Rothstein, J.D.1
-
83
-
-
0029067210
-
CSF and plasma amino acid levels in motor neuron disease — elevation of CSF glutamate in a subset of patients
-
Shaw, P J., Forrest, V, Ince, P. G., Richardson, J. P. & Wastell, H. J. CSF and plasma amino acid levels in motor neuron disease — elevation of CSF glutamate in a subset of patients. Weurodegeneration 4, 209-216 (1995).
-
(1995)
Weurodegeneration
, vol.4
, pp. 209-216
-
-
Shaw, P.J.1
Forrest, V.2
Ince, P.G.3
Richardson, J.P.4
Wastell, H.J.5
-
84
-
-
84984775131
-
Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis. A reapprasial using a new HPLC method with coulometric detection in a large cohort of patients
-
(in the press)
-
Spreux-Varoquaux, O. et al. Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis. A reapprasial using a new HPLC method with coulometric detection in a large cohort of patients. J. Weurol. Sci. (in the press).
-
J. Weurol. Sci
-
-
Spreux-Varoquaux, O.1
-
85
-
-
0029030610
-
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
-
Rothstein, J. D., Van Kammen, M., Levey, A. I., Martin, L. J. & Kuncl, R. W. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann. Weurol. 38, 73-84 (1995).
-
(1995)
Ann. Weurol.
, vol.38
, pp. 73-84
-
-
Rothstein, J.D.1
Van Kammen, M.2
Levey, A.I.3
Martin, L.J.4
Kuncl, R.W.5
-
86
-
-
0032032013
-
Aberrant RNA processing in a neurodegenerative disease: The cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis
-
Lin, C. L. et al. Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis. Weuron 20, 589-602 (1998).
-
(1998)
Weuron
, vol.20
, pp. 589-602
-
-
Lin, C.L.1
-
87
-
-
0032716796
-
The RNA of the glutamate transporter EAAT2 is variably spliced in amyotrophic lateral sclerosis and normal individuals
-
Meyer, T. et al. The RNA of the glutamate transporter EAAT2 is variably spliced in amyotrophic lateral sclerosis and normal individuals. J. Weurol. Sci. 170, 45-50 (1999).
-
(1999)
J. Weurol. Sci.
, vol.170
, pp. 45-50
-
-
Meyer, T.1
-
88
-
-
0034711151
-
Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls
-
Honig, L. S., Chambliss, D. D., Bigio, E. H., Carroll, S. L. & Elliott, J. L. Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls. Weurology 55, 1082-1088 (2000).
-
(2000)
Weurology
, vol.55
, pp. 1082-1088
-
-
Honig, L.S.1
Chambliss, D.D.2
Bigio, E.H.3
Carroll, S.L.4
Elliott, J.L.5
-
89
-
-
0022973208
-
Lathyrism: Evidence for the role of the neuroexcitatory amino acid BOAA
-
Spencer, P. S. et al. Lathyrism: evidence for the role of the neuroexcitatory amino acid BOAA. Lancet 2, 1066-1067 (1986).
-
(1986)
Lancet
, vol.2
, pp. 1066-1067
-
-
Spencer, P.S.1
-
90
-
-
0027741209
-
Guam ALS-PDC: Possible causes
-
Spencer, P. S. et al. Guam ALS-PDC: possible causes. Science 262, 825-826 (1993).
-
(1993)
Science
, vol.262
, pp. 825-826
-
-
Spencer, P.S.1
-
91
-
-
0346604092
-
Nitration of glutamate transporters in transgenic mice with a familial amyotrophic lateral sclerosis-linked SOD1 mutation
-
Nagano, I., Wong, P. C. & Rothstein, J. D. Nitration of glutamate transporters in transgenic mice with a familial amyotrophic lateral sclerosis-linked SOD1 mutation. Ann. Weurol. 40, 542 (1996).
-
(1996)
Ann. Weurol.
, vol.40
, pp. 542
-
-
Nagano, I.1
Wong, P.C.2
Rothstein, J.D.3
-
92
-
-
0034978562
-
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
-
Oosthuyse, B. et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Wature Genet. 28, 131-138 (2001).
-
(2001)
Wature Genet
, vol.28
, pp. 131-138
-
-
Oosthuyse, B.1
-
93
-
-
0032816137
-
Autosomal dominant juvenile amyotrophic lateral sclerosis
-
Rabin, B. A. et al. Autosomal dominant juvenile amyotrophic lateral sclerosis. Brain 122, 1539-1550 (1999).
-
(1999)
Brain
, vol.122
, pp. 1539-1550
-
-
Rabin, B.A.1
-
94
-
-
0031959591
-
Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34
-
Chance, P. F. et al. Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34. Am. J. Hum. Genet. 62, 633-640 (1998).
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 633-640
-
-
Chance, P.F.1
-
95
-
-
0032414948
-
Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers
-
Hentati, A. et al. Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers. Weurogenetics 2, 55-60 (1998).
-
(1998)
Weurogenetics 2
, pp. 55-60
-
-
Hentati, A.1
-
96
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
Hadano, S. et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Wature Genet. 29, 166-173 (2001).
-
(2001)
Wature Genet
, vol.29
, pp. 166-173
-
-
Hadano, S.1
-
97
-
-
0034785509
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
Yang, Y. et al. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Wature Genet. 29, 160-165 (2001).
-
(2001)
Wature Genet
, vol.29
, pp. 160-165
-
-
Yang, Y.1
-
98
-
-
0027210116
-
Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease
-
Ince, P. et al. Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease. Weuropathol. Appl. Weurobiol. 19, 291-299 (1993).
-
(1993)
Weuropathol. Appl. Weurobiol.
, vol.19
, pp. 291-299
-
-
Ince, P.1
-
99
-
-
7844227669
-
Recessive amyotrophic lateral sclerosis families with the D90A SOD1 mutation share a common founder: Evidence for a linked protective factor
-
Al-Chalabi, A. et al. Recessive amyotrophic lateral sclerosis families with the D90A SOD1 mutation share a common founder: evidence for a linked protective factor. Hum. Mol. Genet. 7, 2045-2050 (1998).
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 2045-2050
-
-
Al-Chalabi, A.1
-
100
-
-
0034537966
-
Genetic mapping of a mouse modifier gene that can prevent ALS onset
-
Kunst, C. B., Messer, L., Gordon, J., Haines, J. & Patterson, D. Genetic mapping of a mouse modifier gene that can prevent ALS onset. Genomics 70, 181-189 (2000).
-
(2000)
Genomics
, vol.70
, pp. 181-189
-
-
Kunst, C.B.1
Messer, L.2
Gordon, J.3
Haines, J.4
Patterson, D.5
-
101
-
-
0001389279
-
A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)
-
Kasarkis, E. J. et al. A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III). Weurology 52, 1427-1433 (1999).
-
(1999)
Weurology
, vol.52
, pp. 1427-1433
-
-
Kasarkis, E.J.1
-
102
-
-
0031562362
-
Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats
-
Akbar, M. T. et al. Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats. Weuroscience 78, 351-359 (1997).
-
(1997)
Weuroscience
, vol.78
, pp. 351-359
-
-
Akbar, M.T.1
-
103
-
-
0031722582
-
A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group
-
Borasio, G. D. et al. A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group. Weurology 51, 583-586 (1998).
-
(1998)
Weurology
, vol.51
, pp. 583-586
-
-
Borasio, G.D.1
-
104
-
-
6844266272
-
Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group
-
Lai, E. C. et al. Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group. Weurology 49, 1621-1630 (1997).
-
(1997)
Weurology
, vol.49
, pp. 1621-1630
-
-
Lai, E.C.1
-
105
-
-
0028097839
-
A controlled trial of riluzole in amyotrophic lateral sclerosis
-
Bensimon, G., Lacomblez, L., Meininger, V. & The ALS/Riluzole Study Group. A controlled trial of riluzole in amyotrophic lateral sclerosis. W. Engl. J. Med. 330, 585-591 (1994).
-
(1994)
W. Engl. J. Med.
, vol.330
, pp. 585-591
-
-
Bensimon, G.1
Lacomblez, L.2
Meininger, V.3
-
106
-
-
0029977337
-
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II
-
Lacomblez, L., Bensimon, G., Leigh, P. N., Guillet, P. & Meininger, V. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. Lancet 347, 1425-1431 (1996).
-
(1996)
Lancet
, vol.347
, pp. 1425-1431
-
-
Lacomblez, L.1
Bensimon, G.2
Leigh, P.N.3
Guillet, P.4
Meininger, V.5
-
107
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
Klivenyi, P. et al. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Mature Med. 5, 347-350 (1999).
-
(1999)
Mature Med
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
-
108
-
-
0035051503
-
Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation
-
Andreassen, O. A. et al. Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation. J. Weurochem. 77, 383-390 (2001).
-
(2001)
J. Weurochem.
, vol.77
, pp. 383-390
-
-
Andreassen, O.A.1
-
109
-
-
0035918258
-
Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis
-
Shinder, G. A., Lacourse, M. C., Minotti, S. & Durham, H. D. Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis. J. Biol. Chem. 276, 12791-12796 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12791-12796
-
-
Shinder, G.A.1
Lacourse, M.C.2
Minotti, S.3
Durham, H.D.4
-
110
-
-
0034605478
-
Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21 -q22
-
Hosler, B. A. et al. Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21 -q22. J. Am. Med. Assoc. 284, 1664-1669 (2000).
-
(2000)
J. Am. Med. Assoc.
, vol.284
, pp. 1664-1669
-
-
Hosler, B.A.1
-
111
-
-
0007731688
-
X-linked dominant locus for late-onset familial amyotrophic lateral sclerosis
-
Siddique, T. et al. X-linked dominant locus for late-onset familial amyotrophic lateral sclerosis. Am. J. Hum. Genet. 63, A308 (1998).
-
(1998)
Am. J. Hum. Genet.
, vol.63
, pp. A308
-
-
Siddique, T.1
-
112
-
-
0035947221
-
Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model
-
Jung, C. et al. Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model. Weurosci. Lett. 304, 157-160 (2001).
-
(2001)
Weurosci. Lett.
, vol.304
, pp. 157-160
-
-
Jung, C.1
-
113
-
-
0032827346
-
Therapeutic benefits of putrescine-modified catalase in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Reinholz, M. M., Merkle, C. M. & Poduslo, J. F. Therapeutic benefits of putrescine-modified catalase in a transgenic mouse model of familial amyotrophic lateral sclerosis. Exp. Weurol. 159, 204-216 (1999).
-
(1999)
Exp. Weurol.
, vol.159
, pp. 204-216
-
-
Reinholz, M.M.1
Merkle, C.M.2
Poduslo, J.F.3
-
114
-
-
0035068202
-
Effects of an inhibitor of poly(ADP- ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice
-
Andreassen, O. A. et al. Effects of an inhibitor of poly(ADP- ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice. Exp. Weurol. 168, 419-424 (2001).
-
(2001)
Exp. Weurol.
, vol.168
, pp. 419-424
-
-
Andreassen, O.A.1
-
115
-
-
0034327293
-
Beneficial effect of ginseng root in SOD-1 (G93A) transgenic mice
-
Jiang, F., DeSilva, S. & Turnbull, J. Beneficial effect of ginseng root in SOD-1 (G93A) transgenic mice. J. Weurol. Sci. 180, 52-54 (2000).
-
(2000)
J. Weurol. Sci.
, vol.180
, pp. 52-54
-
-
Jiang, F.1
Desilva, S.2
Turnbull, J.3
-
116
-
-
0034601439
-
I. W-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis
-
Andreassen, O. A., Dedeoglu, A., Klivenyi, P, Beal, M. F & Bush, A. I. W-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis. Weuroreport 11, 2491-2493 (2000).
-
(2000)
Weuroreport
, vol.11
, pp. 2491-2493
-
-
Andreassen, O.A.1
Dedeoglu, A.2
Klivenyi, P.3
Beal, M.F.4
Bush, A.5
-
117
-
-
0035155759
-
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP
-
Andreassen, O. A. et al. Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. Exp. Weurol. 167, 189-195 (2001).
-
(2001)
Exp. Weurol.
, vol.167
, pp. 189-195
-
-
Andreassen, O.A.1
-
118
-
-
0034614353
-
A specific inhibitor of janus kinase-3 increases survival in a transgenic mouse model of amyotrophic lateral sclerosis
-
Trieu, V. N., Liu, R., Liu, X. P. & Uckun, F. M. A specific inhibitor of janus kinase-3 increases survival in a transgenic mouse model of amyotrophic lateral sclerosis. Biochem. Biophys. Res. Commun. 267, 22-25 (2000).
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.267
, pp. 22-25
-
-
Trieu, V.N.1
Liu, R.2
Liu, X.P.3
Uckun, F.M.4
-
119
-
-
0033064535
-
Administration of nitric oxide synthase inhibitors does not alter disease course of amyotrophic lateral sclerosis SOD1 mutant transgenic mice
-
Upton-Rice, M. N., Cudkowicz, M. E., Mathew, R. K., Reif, D. & Brown, R. H. Jr. Administration of nitric oxide synthase inhibitors does not alter disease course of amyotrophic lateral sclerosis SOD1 mutant transgenic mice. Ann. Weurol. 45, 413-414 (1999).
-
(1999)
Ann. Weurol.
, vol.45
, pp. 413-414
-
-
Upton-Rice, M.N.1
Cudkowicz, M.E.2
Mathew, R.K.3
Reif, D.4
Brown, R.H.5
-
120
-
-
0033597218
-
Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice
-
Nagano, S., Ogawa, Y, Yanagihara, T. & Sakoda, S. Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice. Weurosci. Lett. 265, 159-162 (1999).
-
(1999)
Weurosci. Lett.
, vol.265
, pp. 159-162
-
-
Nagano, S.1
Ogawa, Y.2
Yanagihara, T.3
Sakoda, S.4
-
121
-
-
0030050727
-
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
-
Gurney, M. E. et al. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann. Weurol. 39, 147-157 (1996).
-
(1996)
Ann. Weurol.
, vol.39
, pp. 147-157
-
-
Gurney, M.E.1
-
122
-
-
0001897915
-
Carboxyfullerenes as neuroprotective agents
-
Dugan, L. L. et al. Carboxyfullerenes as neuroprotective agents. Proc. Watl Acad. Sci. USA 94, 9434-9439 (1997).
-
(1997)
Proc. Watl Acad. Sci. USA
, vol.94
, pp. 9434-9439
-
-
Dugan, L.L.1
-
123
-
-
0035007860
-
Double-blind, placebo-controlled randomized clinical trial of a-tocopherol (Vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS Riluzole-Tocopherol Study Group
-
Desnuelle, C., Dib, M., Garrel, C. & Favier, A. A double-blind, placebo-controlled randomized clinical trial of a-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS Riluzole-Tocopherol Study Group. Amyotroph. Lateral Scler. Other Motor Weuron Disord. 2, 9-18 (2001).
-
(2001)
Amyotroph. Lateral Scler. Other Motor Weuron Disord.
, vol.2
, pp. 9-18
-
-
Desnuelle, C.1
Dib, M.2
Garrel, C.3
Favier, A.A.4
-
124
-
-
0030862630
-
The copper chelator D-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Hottinger, A. F., Fine, E. G., Gurney M. E., Zurn, A. D. & Aebischer, P. The copper chelator D-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis. Eur. J. Weurosci. 9, 1548-1551 (1997).
-
(1997)
Eur. J. Weurosci.
, vol.9
, pp. 1548-1551
-
-
Hottinger, A.F.1
Fine, E.G.2
Gurney, M.E.3
Zurn, A.D.4
Aebischer, P.5
-
125
-
-
0035896440
-
Intrathecal cyclosporin prolongs survival of late-stage ALS mice
-
Keep, M., Elmer, E., Fong, K S. & Csiszar, K. Intrathecal cyclosporin prolongs survival of late-stage ALS mice. Brain Res. 894, 327-331 (2001).
-
(2001)
Brain Res
, vol.894
, pp. 327-331
-
-
Keep, M.1
Elmer, E.2
Fong, K.S.3
Csiszar, K.4
-
126
-
-
0344609220
-
Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis
-
Barneoud, P & Curet, O. Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis. Exp. Weurol. 155, 243-251 (1999).
-
(1999)
Exp. Weurol.
, vol.155
, pp. 243-251
-
-
Barneoud, P.1
Curet, O.2
-
127
-
-
84984755124
-
COX-2 inhibition prolongs survival in a transgenic mouse model of ALS
-
(in the press)
-
Frank, K. M., Coccia, C., Drachman, D. B. & Rothstein, J. D. COX-2 inhibition prolongs survival in a transgenic mouse model of ALS. Soc. Weurosci.Abstr. 27 (in the press).
-
Soc. Weurosci.Abstr
, vol.27
-
-
Frank, K.M.1
Coccia, C.2
Drachman, D.B.3
Rothstein, J.D.4
-
128
-
-
0027997173
-
Trial of immunosuppression in amyotrophic lateral sclerosis using total lymphoid irradiation
-
Haverkamp, L. J., Smith, R. G. & Appel, S. H. Trial of immunosuppression in amyotrophic lateral sclerosis using total lymphoid irradiation. Ann. Weurol. 36, 253-254 (1994).
-
(1994)
Ann. Weurol.
, vol.36
, pp. 253-254
-
-
Haverkamp, L.J.1
Smith, R.G.2
Appel, S.H.3
-
129
-
-
0023949295
-
A double-blind study of the effectiveness of cyclosporine in amyotrophic lateral sclerosis
-
Appel, S. H. et al. A double-blind study of the effectiveness of cyclosporine in amyotrophic lateral sclerosis. Arch. Weurol. 45, 381-386 (1988).
-
(1988)
Arch. Weurol.
, vol.45
, pp. 381-386
-
-
Appel, S.H.1
-
130
-
-
0022521502
-
Intrathecal administration of natural human interferon a in amyotrophic lateral sclerosis
-
Mora, J. S. et al. Intrathecal administration of natural human interferon a in amyotrophic lateral sclerosis. Weurology 36, 1137-1140 (1986).
-
(1986)
Weurology
, vol.36
, pp. 1137-1140
-
-
Mora, J.S.1
-
131
-
-
0022570201
-
Therapeutic plasmapheresis and plasma exchange
-
Patten, E. Therapeutic plasmapheresis and plasma exchange. Crit. Rev. Clin. Lab. Sci. 23, 147-175 (1986).
-
(1986)
Crit. Rev. Clin. Lab. Sci.
, vol.23
, pp. 147-175
-
-
Patten, E.1
-
132
-
-
0021241929
-
Ganglioside therapy for amyotrophic lateral sclerosis: A double-blind controlled trial
-
Harrington, H., Hallett, M. & Tyler, H. R. Ganglioside therapy for amyotrophic lateral sclerosis: a double-blind controlled trial. Weurology 34, 1083-1085 (1984).
-
(1984)
Weurology
, vol.34
, pp. 1083-1085
-
-
Harrington, H.1
Hallett, M.2
Tyler, H.R.3
-
133
-
-
0021253595
-
A double-blind controlled trial of bovine brain gangliosides in amyotrophic lateral sclerosis
-
Bradley, W. G. et al. A double-blind controlled trial of bovine brain gangliosides in amyotrophic lateral sclerosis. Weurology 34, 1079-1082 (1984).
-
(1984)
Weurology
, vol.34
, pp. 1079-1082
-
-
Bradley, W.G.1
-
134
-
-
0021306178
-
Trials of ganglioside therapy for amyotrophic lateral sclerosis and diabetic neuropathy
-
Hallett, M., Harrington, H., Tyler, H. R., Flood, T. & Slater, N. Trials of ganglioside therapy for amyotrophic lateral sclerosis and diabetic neuropathy. Adv. Exp. Med. Biol. 174, 575-579 (1984).
-
(1984)
Adv. Exp. Med. Biol.
, vol.174
, pp. 575-579
-
-
Hallett, M.1
Harrington, H.2
Tyler, H.R.3
Flood, T.4
Slater, N.5
-
135
-
-
0021298875
-
Double-blind controlled trial of purified brain gangliosides in amyotrophic lateral sclerosis and experience with peripheral neuropathies
-
Bradley, W. G. Double-blind controlled trial of purified brain gangliosides in amyotrophic lateral sclerosis and experience with peripheral neuropathies. Adv. Exp. Med. Biol. 174, 565-573 (1984).
-
(1984)
Adv. Exp. Med. Biol.
, vol.174
, pp. 565-573
-
-
Bradley, W.G.1
-
136
-
-
1842407161
-
Inhibition of ICE slows ALS in mice
-
Friedlander, R. M., Brown, R. H., Gagliardini, V, Wang, J. & Yuan, J. Inhibition of ICE slows ALS in mice. Wature 388, 31 (1997).
-
(1997)
Wature
, vol.388
, pp. 31
-
-
Friedlander, R.M.1
Brown, R.H.2
Gagliardini, V.3
Wang, J.4
Yuan, J.5
-
137
-
-
0034613225
-
Motor neuron cell death in a mouse model of FALS is not mediated by the p53 cell survival regulator
-
Prudlo, J. et al. Motor neuron cell death in a mouse model of FALS is not mediated by the p53 cell survival regulator. Brain Res. 879, 183-187 (2000).
-
(2000)
Brain Res
, vol.879
, pp. 183-187
-
-
Prudlo, J.1
-
138
-
-
0030006282
-
A clinical trial of verapamil in amyotrophic lateral sclerosis
-
Miller, R. G. et al. A clinical trial of verapamil in amyotrophic lateral sclerosis. Muscle Wen/e 19, 511-515 (1996).
-
(1996)
Muscle Wen/E
, vol.19
, pp. 511-515
-
-
Miller, R.G.1
-
139
-
-
0029923440
-
Controlled trial of nimodipine in amyotrophic lateral sclerosis
-
Miller, R. G. et al. Controlled trial of nimodipine in amyotrophic lateral sclerosis. Weuromuscul. Disord. 6, 101-104 (1996).
-
(1996)
Weuromuscul. Disord.
, vol.6
, pp. 101-104
-
-
Miller, R.G.1
-
140
-
-
0347233783
-
Naaladase inhibition increases survival and delays clinical symptoms in SOD transgenic model of ALS
-
Slusher, B. S. et al. Naaladase inhibition increases survival and delays clinical symptoms in SOD transgenic model of ALS. Soc. Weurosci. Abstr. 26, 43.10 (2000).
-
(2000)
Soc. Weurosci. Abstr.
, vol.26
, Issue.43
, pp. 10
-
-
Slusher, B.S.1
-
141
-
-
84884526436
-
EAAT2 overexpression plays a neuroprotective role in the SOD1 G93A model of amyotrophic lateral sclerosis
-
(in the press)
-
Sutherland, M. L., Martinowich, K. & Rothstein, J. D. EAAT2 overexpression plays a neuroprotective role in the SOD1 G93A model of amyotrophic lateral sclerosis. Soc. Weurosci. Abstr. 27, (in the press).
-
Soc. Weurosci. Abstr
, vol.27
-
-
Sutherland, M.L.1
Martinowich, K.2
Rothstein, J.D.3
-
142
-
-
0023913736
-
Pilot trial of branched-chain amino acids in amyotrophic lateral sclerosis
-
Plaitakis, A., Smith, J., Mandeli, J. & Yahr, M. D. Pilot trial of branched-chain amino acids in amyotrophic lateral sclerosis. Lancet 1, 1015-1018 (1988).
-
(1988)
Lancet
, vol.1
, pp. 1015-1018
-
-
Plaitakis, A.1
Smith, J.2
Mandeli, J.3
Yahr, M.D.4
-
143
-
-
0033587480
-
Intramuscular grafts of myoblasts genetically modified to secrete glial cell line-derived neurotrophic factor prevent motoneuron loss and disease progression in a mouse model of familial amyotrophic lateral sclerosis
-
Mohajeri, M. H., Figlewicz, D. A. & Bohn, M. C. Intramuscular grafts of myoblasts genetically modified to secrete glial cell line-derived neurotrophic factor prevent motoneuron loss and disease progression in a mouse model of familial amyotrophic lateral sclerosis. Hum. Gene Tier. 10, 1853-1866 (1999).
-
(1999)
Hum. Gene Tier.
, vol.10
, pp. 1853-1866
-
-
Mohajeri, M.H.1
Figlewicz, D.A.2
Bohn, M.C.3
-
144
-
-
84984762646
-
Intracisternal injection of bone morphogenic protein-7 at time of disease onset did not alter disease course in a transgenic mouse model of amyotrophic lateral sclerosis
-
Dreibelbis, J. E., Cudkowicz, M. E., Pastuszak, K. A., Smith, E. R. & Brown, R. H. Jr. Intracisternal injection of bone morphogenic protein-7 at time of disease onset did not alter disease course in a transgenic mouse model of amyotrophic lateral sclerosis. Soc. Weurosci.Abstr. 26, 865-4 (2000).
-
(2000)
Soc. Weurosci.Abstr.
, vol.26
, pp. 865-874
-
-
Dreibelbis, J.E.1
Cudkowicz, M.E.2
Pastuszak, K.A.3
Smith, E.R.4
Brown, R.H.5
-
145
-
-
0035444173
-
Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice
-
Bordet, T. et al. Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice. Hum. Mol. Genet. 10, 1925-1933 (2001).
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1925-1933
-
-
Bordet, T.1
-
146
-
-
0345972723
-
Hepatocyte growth factor gene transfer improves life span, motor function and motorneuronal death in an ALS transgenic mouse model
-
(in the press)
-
Sun, W. & Funakoshi, H. N. T. Hepatocyte growth factor gene transfer improves life span, motor function and motorneuronal death in an ALS transgenic mouse model. Soc. Weurosci. Abstr. 27, (in the press).
-
Soc. Weurosci. Abstr
, vol.27
-
-
Sun, W.1
Funakoshi, H.2
-
147
-
-
0026729250
-
Intrathecal thyrotropin-releasing hormone does not alter the progressive course of ALS: Experience with an intrathecal drug delivery system
-
Munsat, T. L. et al. Intrathecal thyrotropin-releasing hormone does not alter the progressive course of ALS: experience with an intrathecal drug delivery system. Weurology 42, 1049-1053 (1992).
-
(1992)
Weurology
, vol.42
, pp. 1049-1053
-
-
Munsat, T.L.1
-
148
-
-
0023142099
-
Intravenous thyrotropin- releasing hormone in patients with amyotrophic lateral sclerosis. Dose-response and randomized concurrent placebo-controlled pilot studies
-
Brooks, B. R., Sufit, R. L., Montgomery, G. K., Beaulieu, D. A. & Erickson, L. M. Intravenous thyrotropin- releasing hormone in patients with amyotrophic lateral sclerosis. Dose-response and randomized concurrent placebo-controlled pilot studies. Weurol. Clin. 5, 143-158 (1987).
-
(1987)
Weurol. Clin.
, vol.5
, pp. 143-158
-
-
Brooks, B.R.1
Sufit, R.L.2
Montgomery, G.K.3
Beaulieu, D.A.4
Erickson, L.M.5
-
149
-
-
0022636979
-
A double-blind, placebo-controlled trial of TRH in amyotrophic lateral sclerosis
-
Caroscio, J. T. et al. A double-blind, placebo-controlled trial of TRH in amyotrophic lateral sclerosis. Weurology 36, 141-145 (1986).
-
(1986)
Weurology
, vol.36
, pp. 141-145
-
-
Caroscio, J.T.1
-
150
-
-
0033583834
-
Genistein is neuroprotective in murine models of familial amyotrophic lateral sclerosis and stroke
-
Trieu, V N. & Uckun, F. M. Genistein is neuroprotective in murine models of familial amyotrophic lateral sclerosis and stroke. Biochem. Biophys. Res. Commun. 258, 685-688 (1999).
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.258
, pp. 685-688
-
-
Trieu, V.N.1
Uckun, F.M.2
-
151
-
-
0022518578
-
Trial of octacosanol in amyotrophic lateral sclerosis
-
Norris, F. H., Denys, E. H. & Fallat, R. J. Trial of octacosanol in amyotrophic lateral sclerosis. Weurology 36, 1263-1264 (1986).
-
(1986)
Weurology
, vol.36
, pp. 1263-1264
-
-
Norris, F.H.1
Denys, E.H.2
Fallat, R.J.3
-
152
-
-
0019453541
-
Amantadine and guanidine are ineffective in ALS
-
Munsat, T. L., Easterday, C. S., Levy, S., Wolff, S. M. & Hiatt, R. Amantadine and guanidine are ineffective in ALS. Weurology 31, 1054-1055 (1981).
-
(1981)
Weurology
, vol.31
, pp. 1054-1055
-
-
Munsat, T.L.1
Easterday, C.S.2
Levy, S.3
Wolff, S.M.4
Hiatt, R.5
-
153
-
-
0018321151
-
Transfer factor is ineffective in amyotrophic lateral sclerosis
-
Olarte, M. R., Gersten, J. C., Zabriskie, J. & Rowland, L. P. Transfer factor is ineffective in amyotrophic lateral sclerosis. Ann. Weurol. 5, 385-388 (1979).
-
(1979)
Ann. Weurol.
, vol.5
, pp. 385-388
-
-
Olarte, M.R.1
Gersten, J.C.2
Zabriskie, J.3
Rowland, L.P.4
-
154
-
-
0018075269
-
Therapeutic trial of tilorone in ALS: Lack of benefit in a double-blind, placebo-controlled study
-
Olson, W. H., Simons, J. A. & Halaas, G. W. Therapeutic trial of tilorone in ALS: lack of benefit in a double-blind, placebo-controlled study. Weurology 28, 1293-1295 (1978).
-
(1978)
Weurology
, vol.28
, pp. 1293-1295
-
-
Olson, W.H.1
Simons, J.A.2
Halaas, G.W.3
-
155
-
-
0015128099
-
The use of isoprinosine in patients with amyotrophic lateral sclerosis
-
Fareed, G. C. & Tyler, H. R. The use of isoprinosine in patients with amyotrophic lateral sclerosis. Weurology 21, 937-940 (1971).
-
(1971)
Weurology
, vol.21
, pp. 937-940
-
-
Fareed, G.C.1
Tyler, H.R.2
-
156
-
-
0034717016
-
Human umbilical cord blood effect on sod mice (Amyotrophic lateral sclerosis)
-
Ende, N., Weinstein, F, Chen, R. & Ende, M. Human umbilical cord blood effect on sod mice (amyotrophic lateral sclerosis). Life Sci. 67, 53-59 (2000).
-
(2000)
Life Sci
, vol.67
, pp. 53-59
-
-
Ende, N.1
Weinstein, F.2
Chen, R.3
Ende, M.4
-
157
-
-
0141613347
-
Transplanted neural stem cells are capable of engraftment and diffrentiation in transgenic mutant SOD1 mice
-
Maragakis, N. J. et al. Transplanted neural stem cells are capable of engraftment and diffrentiation in transgenic mutant SOD1 mice. Soc. Weurosci.Abstr. 26, 668.3 (2000).
-
(2000)
Soc. Weurosci.Abstr.
, vol.26
, Issue.668
, pp. 3
-
-
Maragakis, N.J.1
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