-
2
-
-
0027401203
-
Mutations in Cu/Zn Superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen DR, Siddique T, Patterson D, et al. Mutations in Cu/Zn Superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993:362:59-62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
-
3
-
-
0028940996
-
Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis
-
Bowling AC, Barkowski EE, McKenna-Yasek D, et al. Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis. J Neurochem 1995:64:2366-2369
-
(1995)
J Neurochem
, vol.64
, pp. 2366-2369
-
-
Bowling, A.C.1
Barkowski, E.E.2
McKenna-Yasek, D.3
-
4
-
-
15844393658
-
Motor neurons in Cu/Zn Superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
Reaume AG, Elliott JL, Huffman EK, et al. Motor neurons in Cu/Zn Superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet 1996:13:43-47
-
(1996)
Nat Genet
, vol.13
, pp. 43-47
-
-
Reaume, A.G.1
Elliott, J.L.2
Huffman, E.K.3
-
5
-
-
0028960506
-
Amyotrophic lateral sclerosis: Recent insights from genetics and transgenic mice
-
Brown RH Jr. Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice. Cell 1995:80:687-692
-
(1995)
Cell
, vol.80
, pp. 687-692
-
-
Brown Jr., R.H.1
-
6
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu.Zn Superoxide dismutase mutation
-
Gurney ME, Chiu AY, Dal Canto MC, et al. Motor neuron degeneration in mice that express a human Cu.Zn Superoxide dismutase mutation. Science 1994;264:1772-1775
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Chiu, A.Y.2
Dal Canto, M.C.3
-
7
-
-
0028888945
-
Transgenic mice expressing an altered murine Superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
-
Ripps ME, Huntley GW, Hof PR, et al. Transgenic mice expressing an altered murine Superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc Natl Acad Sei USA 1995:92:689-693
-
(1995)
Proc Natl Acad Sei USA
, vol.92
, pp. 689-693
-
-
Ripps, M.E.1
Huntley, G.W.2
Hof, P.R.3
-
8
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
Wong PC, Pardo CA, Borchelt DR, et al. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 1995:14:1105-1116
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
-
9
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu.Zn Superoxide dismutase
-
Deng H-X, Hentati A, Tainer JA, et al. Amyotrophic lateral sclerosis and structural defects in Cu.Zn Superoxide dismutase. Science 1993:261:1047-1051
-
(1993)
Science
, vol.261
, pp. 1047-1051
-
-
Deng, H.-X.1
Hentati, A.2
Tainer, J.A.3
-
10
-
-
16044366720
-
Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein
-
Lyons TJ, Liu H, Goto JJ, et al. Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein. Proc Natl Acad Sei USA 1996:93:12240-12244
-
(1996)
Proc Natl Acad Sei USA
, vol.93
, pp. 12240-12244
-
-
Lyons, T.J.1
Liu, H.2
Goto, J.J.3
-
11
-
-
0029671220
-
Altered reactivity of Superoxide dismutase in familial amyotrophic lateral sclerosis
-
Wiedau-Pazos M, Goto JJ, Rabizadeh S, et al. Altered reactivity of Superoxide dismutase in familial amyotrophic lateral sclerosis. Science 1996;271:515-518
-
(1996)
Science
, vol.271
, pp. 515-518
-
-
Wiedau-Pazos, M.1
Goto, J.J.2
Rabizadeh, S.3
-
12
-
-
0029939471
-
A gain-of-function of an amyotrophic lateral sclerosis-associated Cu.Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide
-
Yim MB, Kang J-H, Yim H-S, et al. A gain-of-function of an amyotrophic lateral sclerosis-associated Cu.Zn-superoxide dismutase mutant: an enhancement of free radical formation due to a decrease in Km for hydrogen peroxide. Proc Natl Acad Sei USA 1996:93:5709-5714
-
(1996)
Proc Natl Acad Sei USA
, vol.93
, pp. 5709-5714
-
-
Yim, M.B.1
Kang, J.-H.2
Yim, H.-S.3
-
13
-
-
0027293275
-
ALS, SOD and peroxynitrite
-
Letter
-
Beckman JS, Carson M, Smith CD, Koppenol WH. ALS, SOD and peroxynitrite. Nature 1993:364:584 (Letter)
-
(1993)
Nature
, vol.364
, pp. 584
-
-
Beckman, J.S.1
Carson, M.2
Smith, C.D.3
Koppenol, W.H.4
-
14
-
-
0026439963
-
Kinetics of superoxide dismutase- And iron-catalyzed nitration of phenolics by peroxynitrite
-
Beckman JS, Ischiropoulos H, Zhu L, et al. Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite. Arch Biochem Biophys 1992:298:438-445
-
(1992)
Arch Biochem Biophys
, vol.298
, pp. 438-445
-
-
Beckman, J.S.1
Ischiropoulos, H.2
Zhu, L.3
-
15
-
-
0026485192
-
Peroxynitrite-mediated tyrosine nitration catalyzed by Superoxide dismutase
-
Ischiropoulos H, Zhu L, Chen J, et al. Peroxynitrite-mediated tyrosine nitration catalyzed by Superoxide dismutase. Arch Biochem Biophys 1992:298:431-437
-
(1992)
Arch Biochem Biophys
, vol.298
, pp. 431-437
-
-
Ischiropoulos, H.1
Zhu, L.2
Chen, J.3
-
16
-
-
33847449985
-
Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
-
Dal Canto MC, Gurney ME. Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am J Pathol 1994;l45:12711280
-
(1994)
Am J Pathol
, vol.45
, pp. 12711280
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
17
-
-
0028933344
-
Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu.Zn SOD, and in mice overexpressing wild rype human SOD: A model of familial amyotrophic lateral sclerosis (FALS)
-
Dal Canto MC, Gurney ME. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu.Zn SOD, and in mice overexpressing wild rype human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Res 1995:676:25-40
-
(1995)
Brain Res
, vol.676
, pp. 25-40
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
18
-
-
0025161567
-
Kynurenine pathway measurements in Huntington's disease striatum: Evidence for reduced formation of kynurenic acid
-
Béai MF, Maison WR, Swartz KJ, et al. Kynurenine pathway measurements in Huntington's disease striatum: evidence for reduced formation of kynurenic acid. J Neurochem 1990;55: 1327-1339
-
(1990)
J Neurochem
, vol.55
, pp. 1327-1339
-
-
Béai, M.F.1
Maison, W.R.2
Swartz, K.J.3
-
19
-
-
13344261420
-
Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo
-
Schulz JB, Matthews RT, Jenkins BG, et al. Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo. J Neurosci 1995:15:8419-8429
-
(1995)
J Neurosci
, vol.15
, pp. 8419-8429
-
-
Schulz, J.B.1
Matthews, R.T.2
Jenkins, B.G.3
-
20
-
-
0028304790
-
High-performance liquid chromatography-based thiobarbituric acid tests
-
Chirico S. High-performance liquid chromatography-based thiobarbituric acid tests. Methods Enzymol 1994:223:314-318
-
(1994)
Methods Enzymol
, vol.223
, pp. 314-318
-
-
Chirico, S.1
-
21
-
-
0027396021
-
Excitotoxin lesions in primates as a model for Huntington's disease: Histopathologic and neutochemical characterization
-
Ferrante RJ, Kowall NW, Cipolloni PB, et al. Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neutochemical characterization. Exp Neurol 1993:119:46-71
-
(1993)
Exp Neurol
, vol.119
, pp. 46-71
-
-
Ferrante, R.J.1
Kowall, N.W.2
Cipolloni, P.B.3
-
22
-
-
0029966363
-
Transgenic mice carrying a human mutant Superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
-
Tu P-H, Raju P, Robinson KA, et al. Transgenic mice carrying a human mutant Superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc Natl Acad Sei USA 1996:93:31553160
-
(1996)
Proc Natl Acad Sei USA
, vol.93
, pp. 31553160
-
-
Tu, P.-H.1
Raju, P.2
Robinson, K.A.3
-
23
-
-
0025189864
-
Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and Superoxide
-
Beckman JS, Beckman TW, Chen J, et al. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and Superoxide. Proc Natl Acad Sei USA 1990:87:1620-1624
-
(1990)
Proc Natl Acad Sei USA
, vol.87
, pp. 1620-1624
-
-
Beckman, J.S.1
Beckman, T.W.2
Chen, J.3
-
25
-
-
0028796770
-
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP induced neurotoxicity in mice
-
Schulz JB, Matthews RT, Muqit MMK, et al. Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP induced neurotoxicity in mice. J Neurochem 1995:64:936-939
-
(1995)
J Neurochem
, vol.64
, pp. 936-939
-
-
Schulz, J.B.1
Matthews, R.T.2
Muqit, M.M.K.3
-
26
-
-
0025369970
-
The measurement and mechanism of lipid peroxidation in biological systems
-
Gutteridge JMC, Halliwell B. The measurement and mechanism of lipid peroxidation in biological systems. Trends Biochem Sei 1990;15:129-135
-
(1990)
Trends Biochem Sei
, vol.15
, pp. 129-135
-
-
Gutteridge, J.M.C.1
Halliwell, B.2
-
27
-
-
0027300736
-
Lipid peroxidation: Its mechanism, measurement, and significance
-
Halliwell B, Chirico S. Lipid peroxidation: its mechanism, measurement, and significance. Am J Clin Nutr 1993:57:7155725S
-
(1993)
Am J Clin Nutr
, vol.57
-
-
Halliwell, B.1
Chirico, S.2
-
28
-
-
0030050727
-
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
-
Gurney ME, Cutting FB, Zhai P, et al. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol 1996:39:147-157
-
(1996)
Ann Neurol
, vol.39
, pp. 147-157
-
-
Gurney, M.E.1
Cutting, F.B.2
Zhai, P.3
-
29
-
-
0028929896
-
Differential expression of heme oxygenase-1 in cultured cortical neurons and astrocytes determined by the aid of a new heme oxygenase antibody
-
Dwyer BE, Nishimura RN, Lu S-Y. Differential expression of heme oxygenase-1 in cultured cortical neurons and astrocytes determined by the aid of a new heme oxygenase antibody. Response to oxidative stress. Mol Brain Res 1995:30:37-47
-
(1995)
Response to Oxidative Stress. Mol Brain Res
, vol.30
, pp. 37-47
-
-
Dwyer, B.E.1
Nishimura, R.N.2
Lu, S.-Y.3
-
30
-
-
0028864283
-
Induction of heme oxygenase-1 (HO-1) after traumatic brain injury in the rat
-
Fukuda K, Panter SS, Sharp FR, Noble LJ. Induction of heme oxygenase-1 (HO-1) after traumatic brain injury in the rat. Neurosci Lett 1995:199:127-130
-
(1995)
Neurosci Lett
, vol.199
, pp. 127-130
-
-
Fukuda, K.1
Panter, S.S.2
Sharp, F.R.3
Noble, L.J.4
-
31
-
-
0028890354
-
Induction of heme oxygenase 1 in the retina by intense visible light: Suppression by the antioxidant dimethylthiourea
-
Kutty RK, Kutty G, Wiggert B, et al. Induction of heme oxygenase 1 in the retina by intense visible light: suppression by the antioxidant dimethylthiourea. Proc Natl Acad Sei USA 1995:92:1177-1181
-
(1995)
Proc Natl Acad Sei USA
, vol.92
, pp. 1177-1181
-
-
Kutty, R.K.1
Kutty, G.2
Wiggert, B.3
-
32
-
-
0029983162
-
Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: Lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide
-
Kong S-K, Yim MB, Stadtman ER, Chock PB. Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide. Proc Natl Acad Sei USA 1996; 93:3377-3382
-
(1996)
Proc Natl Acad Sei USA
, vol.93
, pp. 3377-3382
-
-
Kong, S.-K.1
Yim, M.B.2
Stadtman, E.R.3
Chock, P.B.4
-
33
-
-
0028116467
-
A mutant neurofilament subunit causes massive, selective motor neuron death: Implications for the pathogenesis of human motor neuron disease
-
Lee MK, Marszalek JR, Cleveland DW. A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease. Neuron 1994:13:975-988
-
(1994)
Neuron
, vol.13
, pp. 975-988
-
-
Lee, M.K.1
Marszalek, J.R.2
Cleveland, D.W.3
-
34
-
-
0028001606
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
-
Figlewicz DA, Krizus A, Martinoli MG, et al. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum Mol Genet 1994; 3:1757-1761
-
(1994)
Hum Mol Genet
, vol.3
, pp. 1757-1761
-
-
Figlewicz, D.A.1
Krizus, A.2
Martinoli, M.G.3
-
36
-
-
0029004898
-
Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis
-
Collard J-F, Cote F, Julien J-P. Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis. Nature 1995:375:61-64
-
(1995)
Nature
, vol.375
, pp. 61-64
-
-
Collard, J.-F.1
Cote, F.2
Julien, J.-P.3
-
37
-
-
0029812897
-
Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis
-
Sasaki S, Iwata M. Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis. Neurology 1996;47:535-540
-
(1996)
Neurology
, vol.47
, pp. 535-540
-
-
Sasaki, S.1
Iwata, M.2
-
38
-
-
0028971936
-
Induction of nitrotyrosinelike immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis
-
Abe K, Pan L-H, Watanabe M, et al. Induction of nitrotyrosinelike immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis. Neurosci Lett 1995:199:152-154
-
(1995)
Neurosci Lett
, vol.199
, pp. 152-154
-
-
Abe, K.1
Pan, L.-H.2
Watanabe, M.3
-
40
-
-
0029991827
-
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: An immunohistochemical study
-
Chou SM, Wang HS, Komai K. Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study. J Chem Neuroanat 1996;10:249-258
-
(1996)
J Chem Neuroanat
, vol.10
, pp. 249-258
-
-
Chou, S.M.1
Wang, H.S.2
Komai, K.3
-
41
-
-
0029840369
-
Role of SOD-1 and nitric oxide/cyclic GMP cascade on neurofilament aggregatin in ALS/ MND
-
Chou SM, Wang HS, Taniguchi A. Role of SOD-1 and nitric oxide/cyclic GMP cascade on neurofilament aggregatin in ALS/ MND. J Neurol Sei 1996:139:16-26
-
(1996)
J Neurol Sei
, vol.139
, pp. 16-26
-
-
Chou, S.M.1
Wang, H.S.2
Taniguchi, A.3
-
42
-
-
1842368366
-
Carboxybuckminsterfullerenes: Novel antioxidants with neuroprotective efficacy in vitro and in a mouse model of ALS
-
Abstract
-
Dugan LL, Turetsky DM, Du C, et al. Carboxybuckminsterfullerenes: novel antioxidants with neuroprotective efficacy in vitro and in a mouse model of ALS. Soc Neurosci Abstr 1996:22:2142 (Abstract)
-
(1996)
Soc Neurosci Abstr
, vol.22
, pp. 2142
-
-
Dugan, L.L.1
Turetsky, D.M.2
Du, C.3
-
43
-
-
0000614594
-
Is neuronal nitric oxide synthase involved in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Abstract
-
Sasaki M, Facchinetti F, Christov V, et al. Is neuronal nitric oxide synthase involved in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis. Soc Neurosci Abstr 1996;22:2142 (Abstract)
-
(1996)
Soc Neurosci Abstr
, vol.22
, pp. 2142
-
-
Sasaki, M.1
Facchinetti, F.2
Christov, V.3
|