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Volumn 6, Issue 5, 1999, Pages 335-346

Preclinical testing of neuroprotective neurotrophic factors in a model of chronic motor neuron degeneration

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID DERIVATIVE; BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLINE ACETYLTRANSFERASE; CILIARY NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLUTAMIC ACID; NEUROTROPHIC FACTOR; NEUROTROPHIN 3; NEUROTROPHIN 4; SOMATOMEDIN C;

EID: 0032702435     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1006/nbdi.1999.0253     Document Type: Article
Times cited : (90)

References (73)
  • 1
    • 2442646665 scopus 로고    scopus 로고
    • Neurology. 46:1996;1244-1249.
    • (1996) Neurology , vol.46 , pp. 1244-1249
  • 2
    • 0026691620 scopus 로고
    • Effects of astrocytes, insulin, and insulin-like growth factor I on the survival of motoneurons in vitro
    • Ang L. C., Bhaumick B., Munoz D. G., Sass J., Juurlink B. H. J. Effects of astrocytes, insulin, and insulin-like growth factor I on the survival of motoneurons in vitro. J. Neurol. Sci. 109:1992;168-172.
    • (1992) J. Neurol. Sci. , vol.109 , pp. 168-172
    • Ang, L.C.1    Bhaumick, B.2    Munoz, D.G.3    Sass, J.4    Juurlink, B.H.J.5
  • 3
    • 0025514410 scopus 로고
    • Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines
    • Arakawa Y., Sendtner M., Thoenon H. Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines. J. Neurosci. 10:1990;3507-3515.
    • (1990) J. Neurosci. , vol.10 , pp. 3507-3515
    • Arakawa, Y.1    Sendtner, M.2    Thoenon, H.3
  • 4
    • 0026098977 scopus 로고
    • Expression of choline acetyltransferase and nerve growth factor receptor within hypoglossal motoneuron following nerve injury
    • Armstrong D. M., Brady R., Hersh L. B., Hayes R. C., Wiley R. G. Expression of choline acetyltransferase and nerve growth factor receptor within hypoglossal motoneuron following nerve injury. J. Comp. Neurol. 304:1991;596-607.
    • (1991) J. Comp. Neurol. , vol.304 , pp. 596-607
    • Armstrong, D.M.1    Brady, R.2    Hersh, L.B.3    Hayes, R.C.4    Wiley, R.G.5
  • 6
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • Bensimon G., Lacomblez L., Meininger V. A controlled trial of riluzole in amyotrophic lateral sclerosis. N. Engl. J. Med. 330:1994;585-591.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 8
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 71:1976;248-254.
    • (1976) Anal. Biochem. , vol.71 , pp. 248-254
    • Bradford, M.M.1
  • 9
    • 0032189448 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and basic fibroblast growth factor downregulate NMDA receptor function in cerebellar granule cells
    • Brandoli C., Sanna A., De Bernardi M. A., Follesa P., Brooker G., Mocchetti I. Brain-derived neurotrophic factor and basic fibroblast growth factor downregulate NMDA receptor function in cerebellar granule cells. J. Neurosci. 18:1998;7953-7961.
    • (1998) J. Neurosci. , vol.18 , pp. 7953-7961
    • Brandoli, C.1    Sanna, A.2    De Bernardi, M.A.3    Follesa, P.4    Brooker, G.5    Mocchetti, I.6
  • 10
    • 0000675639 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in amyotrophic lateral sclerosis: A failed drug or a failed trial
    • Cedarbaum J. M., Stambler N., Brooks B. R., Bradley W. Brain-derived neurotrophic factor in amyotrophic lateral sclerosis: A failed drug or a failed trial. Ann. Neurol. 44:1998;506-507.
    • (1998) Ann. Neurol. , vol.44 , pp. 506-507
    • Cedarbaum, J.M.1    Stambler, N.2    Brooks, B.R.3    Bradley, W.4
  • 12
    • 0028321583 scopus 로고
    • Neurotrophin-4/5 protects hippocampal and cortical neurons against energy deprivation and excitatory amino acid-induced injury
    • Cheng B., Goodman Y., Begley J. G., Mattson M. P. Neurotrophin-4/5 protects hippocampal and cortical neurons against energy deprivation and excitatory amino acid-induced injury. Brain Res. 650:1994;331-335.
    • (1994) Brain Res. , vol.650 , pp. 331-335
    • Cheng, B.1    Goodman, Y.2    Begley, J.G.3    Mattson, M.P.4
  • 13
    • 0028862867 scopus 로고
    • PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: Evidence for induction of antioxidant pathways
    • Cheng B., Mattson M. P. PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: Evidence for induction of antioxidant pathways. Neuroscience. 15:1995;7095-7104.
    • (1995) Neuroscience , vol.15 , pp. 7095-7104
    • Cheng, B.1    Mattson, M.P.2
  • 14
    • 0003299278 scopus 로고
    • Organotypic spinal cord cultures and a model of chronic glutamate-mediated motor neuron degeneration
    • S. T. Ohnishi, & T. Ohnishi. New York: CRC Press
    • Corse A. M., Rothstein J. D. Organotypic spinal cord cultures and a model of chronic glutamate-mediated motor neuron degeneration. Ohnishi S. T., Ohnishi T. Central Nervous System Trauma Research Techniques. 1995;341-351 CRC Press, New York.
    • (1995) Central Nervous System Trauma Research Techniques , pp. 341-351
    • Corse, A.M.1    Rothstein, J.D.2
  • 17
    • 0032513554 scopus 로고    scopus 로고
    • RET-like immunostaining of spinal motoneurons in amyotrophic lateral sclerosis
    • Duberley R. M., Johnson I. P., Martin J. E., Anand P. RET-like immunostaining of spinal motoneurons in amyotrophic lateral sclerosis. Brain Res. 789:1998;351-354.
    • (1998) Brain Res. , vol.789 , pp. 351-354
    • Duberley, R.M.1    Johnson, I.P.2    Martin, J.E.3    Anand, P.4
  • 19
    • 0016468979 scopus 로고
    • A rapid radiochemical method for the determination of choline acetyltransferase
    • Fonnum F. A rapid radiochemical method for the determination of choline acetyltransferase. J. Neurochem. 24:1975;407-409.
    • (1975) J. Neurochem. , vol.24 , pp. 407-409
    • Fonnum, F.1
  • 23
    • 17344369235 scopus 로고    scopus 로고
    • Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro
    • Hanson M. G., Shen S., Wiemelt A. P., McMorris F. A., Barres B. Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro. J. Neurosci. 18:1998;7361-7368.
    • (1998) J. Neurosci. , vol.18 , pp. 7361-7368
    • Hanson, M.G.1    Shen, S.2    Wiemelt, A.P.3    McMorris, F.A.4    Barres, B.5
  • 26
    • 0027399644 scopus 로고
    • Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain
    • Ip N. Y., Wiegand S. J., Morse J., Rudge J. S. Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain. Eur. J. Neurosci. 5:1993;25-533.
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 25-533
    • Ip, N.Y.1    Wiegand, S.J.2    Morse, J.3    Rudge, J.S.4
  • 27
    • 0025240761 scopus 로고
    • Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance
    • Jackson G. R., Apffel L., Werrbach-Perez K., Perez-Polo J. R. Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance. J. Neurosci. Res. 25:1990;360-368.
    • (1990) J. Neurosci. Res. , vol.25 , pp. 360-368
    • Jackson, G.R.1    Apffel, L.2    Werrbach-Perez, K.3    Perez-Polo, J.R.4
  • 28
    • 0032190095 scopus 로고    scopus 로고
    • Spinal cord neuronal precursors generate multiple neuronal phenotypes in culture
    • Kalyani A. J., Piper D., Mujtaba T., Lucero M. T., Rao M. S. Spinal cord neuronal precursors generate multiple neuronal phenotypes in culture. J. Neurosci. 18:1998;7856-7868.
    • (1998) J. Neurosci. , vol.18 , pp. 7856-7868
    • Kalyani, A.J.1    Piper, D.2    Mujtaba, T.3    Lucero, M.T.4    Rao, M.S.5
  • 29
    • 0031128211 scopus 로고    scopus 로고
    • BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth
    • Kishino A., Ishige Y., Tatsuno T., Nakayama C., Noguchi H. BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth. Exp. Neurol. 144:1997;273-286.
    • (1997) Exp. Neurol. , vol.144 , pp. 273-286
    • Kishino, A.1    Ishige, Y.2    Tatsuno, T.3    Nakayama, C.4    Noguchi, H.5
  • 30
    • 0029065517 scopus 로고
    • Potentiated necrosis of cultured cortical neurons by neurotrophins
    • Koh J., Gwag B. J., Lobner D., Choi D. W. Potentiated necrosis of cultured cortical neurons by neurotrophins. Science. 268:1995;573-575.
    • (1995) Science , vol.268 , pp. 573-575
    • Koh, J.1    Gwag, B.J.2    Lobner, D.3    Choi, D.W.4
  • 31
    • 0031831089 scopus 로고    scopus 로고
    • IGF-I stimulates intestinal muscle cell growth by activating distinct PI 3-kinase and MAP kinase pathways
    • Kuemmerle J. F., Bushman T. L. IGF-I stimulates intestinal muscle cell growth by activating distinct PI 3-kinase and MAP kinase pathways. Am. J. Physiol. 275:1998;151-158.
    • (1998) Am. J. Physiol. , vol.275 , pp. 151-158
    • Kuemmerle, J.F.1    Bushman, T.L.2
  • 33
    • 0027976317 scopus 로고
    • Developmental expression of trkC, the neurotrophin-3 receptor, in the mammalian nervous system
    • Lamballe F., Smeyne R. J., Barbacid M. Developmental expression of trkC, the neurotrophin-3 receptor, in the mammalian nervous system. J. Neurosci. 14:1994;14-28.
    • (1994) J. Neurosci. , vol.14 , pp. 14-28
    • Lamballe, F.1    Smeyne, R.J.2    Barbacid, M.3
  • 34
    • 0028279370 scopus 로고
    • Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse
    • Li L., Oppenheim R. W., Lei M., Houenou L. J. Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse. J. Neurobio. 25:1994;759-766.
    • (1994) J. Neurobio. , vol.25 , pp. 759-766
    • Li, L.1    Oppenheim, R.W.2    Lei, M.3    Houenou, L.J.4
  • 35
    • 0028822549 scopus 로고
    • Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor
    • Li L., Wu W., Lin L. H., Lei M., Oppenheim R. W., Houenou L. J. Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc. Natl. Acad. Sci USA. 92:1995;9771-9775.
    • (1995) Proc. Natl. Acad. Sci USA , vol.92 , pp. 9771-9775
    • Li, L.1    Wu, W.2    Lin, L.H.3    Lei, M.4    Oppenheim, R.W.5    Houenou, L.J.6
  • 36
    • 0032032013 scopus 로고    scopus 로고
    • Aberrant RNA processing in a neurodegenerative disease: A common cause for loss of glutamate transport EAAT2 protein in sporadic amyotrophic lateral sclerosis
    • Lin C-L. G., Bristol L. A., Jin L., Dykes-Hoberg M., Crawford T., Rothstein J. D. Aberrant RNA processing in a neurodegenerative disease: A common cause for loss of glutamate transport EAAT2 protein in sporadic amyotrophic lateral sclerosis. Neuron. 20:1998;589-602.
    • (1998) Neuron , vol.20 , pp. 589-602
    • Lin, C.-L.G.1    Bristol, L.A.2    Jin, L.3    Dykes-Hoberg, M.4    Crawford, T.5    Rothstein, J.D.6
  • 37
    • 0026550179 scopus 로고
    • Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro
    • Martinou J. C., Martinou I., Kato A. C. Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro. Neuron. 8:1992;737-744.
    • (1992) Neuron , vol.8 , pp. 737-744
    • Martinou, J.C.1    Martinou, I.2    Kato, A.C.3
  • 38
    • 0030959485 scopus 로고    scopus 로고
    • Long-term survival effects of GDNF on neonatal rat facial motoneurons after axotomy
    • Matheson C. R., Wang J., Collins F. D., Yan Q. Long-term survival effects of GDNF on neonatal rat facial motoneurons after axotomy. Neuroreport. 8:1997;1739-1742.
    • (1997) Neuroreport , vol.8 , pp. 1739-1742
    • Matheson, C.R.1    Wang, J.2    Collins, F.D.3    Yan, Q.4
  • 39
    • 0031048002 scopus 로고    scopus 로고
    • Neuroprotective signal transduction: Relevance to stroke
    • Mattson M. P. Neuroprotective signal transduction: Relevance to stroke. Neurosci. Biobehav. Rev. 21:1997;193-206.
    • (1997) Neurosci. Biobehav. Rev. , vol.21 , pp. 193-206
    • Mattson, M.P.1
  • 40
    • 0027332958 scopus 로고
    • Basic fibroblast growth factor regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in cultures hippocampal neurons
    • Mattson M. P., Kumar K., Cheng B., Wang H., Michaelis E. K. Basic fibroblast growth factor regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in cultures hippocampal neurons. J. Neurosci. 13:1993;4575-4588.
    • (1993) J. Neurosci. , vol.13 , pp. 4575-4588
    • Mattson, M.P.1    Kumar, K.2    Cheng, B.3    Wang, H.4    Michaelis, E.K.5
  • 41
    • 0029150526 scopus 로고
    • 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons
    • 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. J. Neurochem. 65:1995;1740-1751.
    • (1995) J. Neurochem. , vol.65 , pp. 1740-1751
    • Mattson, M.P.1    Lovell, M.A.2    Furukawa, K.3    Markesbery, W.R.4
  • 42
    • 0024345451 scopus 로고
    • Fibroblast growth factor and glutamate: Opposing roles in the generation and degeneration of hippocampal neuroarchitecture
    • Mattson M. P., Murrain M., Guthrie P. B., Kater S. B. Fibroblast growth factor and glutamate: Opposing roles in the generation and degeneration of hippocampal neuroarchitecture. J. Neurosci. 9:1989;3728-3740.
    • (1989) J. Neurosci. , vol.9 , pp. 3728-3740
    • Mattson, M.P.1    Murrain, M.2    Guthrie, P.B.3    Kater, S.B.4
  • 43
    • 85030370213 scopus 로고    scopus 로고
    • Anti-excitotoxic drugs and therapeutic efficacy
    • 1998
    • Miller, R. G. 1998, Anti-excitotoxic drugs and therapeutic efficacy, Muscle Nerve, 22, S52, 1998.
    • (1998) Muscle Nerve , vol.22
    • Miller, R.G.1
  • 44
    • 0020429617 scopus 로고
    • Murine motor neuron disease (the wobbler mouse)
    • Mitsumoto H., Bradley W. G. Murine motor neuron disease (the wobbler mouse). Brain. 105:1982;811-834.
    • (1982) Brain , vol.105 , pp. 811-834
    • Mitsumoto, H.1    Bradley, W.G.2
  • 45
  • 47
    • 0030762723 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo
    • Novikov L., Novikova L., Kellerth J.-O. Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo. Neurosci. 79:1997;765-774.
    • (1997) Neurosci. , vol.79 , pp. 765-774
    • Novikov, L.1    Novikova, L.2    Kellerth, J.-O.3
  • 49
    • 0025811297 scopus 로고
    • Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor
    • Oppenheim R. W., Prevette D., Qin-Wei Y., Collins F., MacDonald J. Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor. Science. 251:1991;1616-1618.
    • (1991) Science , vol.251 , pp. 1616-1618
    • Oppenheim, R.W.1    Prevette, D.2    Qin-Wei, Y.3    Collins, F.4    MacDonald, J.5
  • 50
    • 0027094145 scopus 로고
    • Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death
    • Oppenheim R. W., Qin-Wei Y., Prevette D., Yan Q. Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death. Nature. 360:1992;755-757.
    • (1992) Nature , vol.360 , pp. 755-757
    • Oppenheim, R.W.1    Qin-Wei, Y.2    Prevette, D.3    Yan, Q.4
  • 51
    • 0032513548 scopus 로고    scopus 로고
    • The trophic requirements of mature motoneurons
    • Oorschot D. E., McLennan I. S. The trophic requirements of mature motoneurons. Brain Res. 789:1998;315-321.
    • (1998) Brain Res. , vol.789 , pp. 315-321
    • Oorschot, D.E.1    McLennan, I.S.2
  • 52
    • 0023804850 scopus 로고
    • The neuroexcitotoxic amino acids glutamate and aspartate are altered in the spinal cord and brain in amyotrophic lateral sclerosis
    • Plaitakis A., Constantakakis E., Smith J. The neuroexcitotoxic amino acids glutamate and aspartate are altered in the spinal cord and brain in amyotrophic lateral sclerosis. Ann. Neurol. 24:1988;446-449.
    • (1988) Ann. Neurol. , vol.24 , pp. 446-449
    • Plaitakis, A.1    Constantakakis, E.2    Smith, J.3
  • 53
    • 0027274623 scopus 로고
    • Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity
    • Rothstein J. D., Jin L., Dykes-Hoberg M., Kuncl R. W. Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity. Proc. Natl. Acad. Sci. USA. 90:1993;6591-6595.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6591-6595
    • Rothstein, J.D.1    Jin, L.2    Dykes-Hoberg, M.3    Kuncl, R.W.4
  • 54
    • 0029113872 scopus 로고
    • Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity
    • Rothstein J. D., Kuncl R. W. Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity. J. Neurochem. 65:1995;643-651.
    • (1995) J. Neurochem. , vol.65 , pp. 643-651
    • Rothstein, J.D.1    Kuncl, R.W.2
  • 55
    • 0026597010 scopus 로고
    • Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
    • Rothstein J. D., Martin L. J., Kuncl R. W. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med. 236:1992;1464-1468.
    • (1992) N. Engl. J. Med. , vol.236 , pp. 1464-1468
    • Rothstein, J.D.1    Martin, L.J.2    Kuncl, R.W.3
  • 57
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • Rothstein J. D., Van Kammen M., Levey A., Martin L. J., Kuncl R. W. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann. Neurol. 38:1995;73-84.
    • (1995) Ann. Neurol. , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.3    Martin, L.J.4    Kuncl, R.W.5
  • 58
    • 0029950147 scopus 로고    scopus 로고
    • GDNF slows loss of motorneurons but not axonal degeneration or premature death of pmn/pmn mice
    • Sagot Y., Tan S. A., Hammang J. P., Aebischer P., Kato A. C. GDNF slows loss of motorneurons but not axonal degeneration or premature death of pmn/pmn mice. J. Neurosci. 16:1996;2335-2341.
    • (1996) J. Neurosci. , vol.16 , pp. 2335-2341
    • Sagot, Y.1    Tan, S.A.2    Hammang, J.P.3    Aebischer, P.4    Kato, A.C.5
  • 60
    • 0027070473 scopus 로고
    • Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats and nerve section
    • Sendtner M., Holtmann B., Kolbeck R., Thoenen H., Barde Y. A. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats and nerve section. Nature. 360:1992;757-759.
    • (1992) Nature , vol.360 , pp. 757-759
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3    Thoenen, H.4    Barde, Y.A.5
  • 61
    • 0025325548 scopus 로고
    • Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy
    • Sendtner M., Kreutzberg G. W., Thoenen H. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature. 345:1990;440-441.
    • (1990) Nature , vol.345 , pp. 440-441
    • Sendtner, M.1    Kreutzberg, G.W.2    Thoenen, H.3
  • 62
    • 0026749255 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy
    • Sendtner M., Schmalbruch H., Stockli K. A., Carroll P., Kreutzberg G. W., Thoenen H. Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature. 358:1992;502-504.
    • (1992) Nature , vol.358 , pp. 502-504
    • Sendtner, M.1    Schmalbruch, H.2    Stockli, K.A.3    Carroll, P.4    Kreutzberg, G.W.5    Thoenen, H.6
  • 63
    • 0030927075 scopus 로고    scopus 로고
    • Glutamate excitotoxicity and amyotrophic lateral sclerosis
    • Shaw P. J., Ince P. G. Glutamate excitotoxicity and amyotrophic lateral sclerosis. J. Neurol. 244:1997;S3-S14.
    • (1997) J. Neurol. , vol.244
    • Shaw, P.J.1    Ince, P.G.2
  • 64
    • 0031978372 scopus 로고    scopus 로고
    • Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: Selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway
    • Skaper S. D., Floreani M., Negro A., Facci L., Giusti P. Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: Selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway. J. Neurochem. 70:1998;1859-1868.
    • (1998) J. Neurochem. , vol.70 , pp. 1859-1868
    • Skaper, S.D.1    Floreani, M.2    Negro, A.3    Facci, L.4    Giusti, P.5
  • 65
    • 0026779874 scopus 로고
    • Recombinant human CNTF alters the threshold of hippocampal pyramidal neuron sensitivity to excitotoxin damage: Synergistic effects of monosialogangliosides
    • Skaper S. D., Nergo A., Toso R. D., Facci L. Recombinant human CNTF alters the threshold of hippocampal pyramidal neuron sensitivity to excitotoxin damage: Synergistic effects of monosialogangliosides. J. Neurosci. Res. 33:1993;330-337.
    • (1993) J. Neurosci. Res. , vol.33 , pp. 330-337
    • Skaper, S.D.1    Nergo, A.2    Toso, R.D.3    Facci, L.4
  • 66
    • 0002918293 scopus 로고
    • Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ
    • Sternberger L. A., Sternberger N. H. Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. Proc. Natl. Acad. Sci. USA. 80:1983;6126-6130.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6126-6130
    • Sternberger, L.A.1    Sternberger, N.H.2
  • 68
    • 0004369643 scopus 로고    scopus 로고
    • Insulin-like growth factor-I regulates the caspase cascade in neurons
    • Von Golen C. M., Russell J. W., Feldman E. L. Insulin-like growth factor-I regulates the caspase cascade in neurons. Neurology. 50:1998;S66.005.
    • (1998) Neurology , vol.50 , pp. 66005
    • Von Golen, C.M.1    Russell, J.W.2    Feldman, E.L.3
  • 69
    • 0018135394 scopus 로고
    • Immunochemical demonstration of reversible reduction in choline acetyltransferase concentration in rat hypoglossal nucleus after hypoglossal nerve transection
    • Wooten G. F., Park D. H., Joh T. H., Reis D. J. Immunochemical demonstration of reversible reduction in choline acetyltransferase concentration in rat hypoglossal nucleus after hypoglossal nerve transection. Nature. 275:1978;324-325.
    • (1978) Nature , vol.275 , pp. 324-325
    • Wooten, G.F.1    Park, D.H.2    Joh, T.H.3    Reis, D.J.4
  • 70
    • 0027987963 scopus 로고
    • Implantation of PNS graft inhibits the induction of neuronal nitric oxide synthase and enhances the survival of spinal motoneurons following root avulsion
    • Wu W., Han K., Li L., Schinco F. P. Implantation of PNS graft inhibits the induction of neuronal nitric oxide synthase and enhances the survival of spinal motoneurons following root avulsion. Exp. Neurol. 129:1994;335-339.
    • (1994) Exp. Neurol. , vol.129 , pp. 335-339
    • Wu, W.1    Han, K.2    Li, L.3    Schinco, F.P.4
  • 71
    • 0027067035 scopus 로고
    • Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy induced cell death
    • Yan Q., Elliott J., Snider W. D. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy induced cell death. Nature. 360:1992;753-755.
    • (1992) Nature , vol.360 , pp. 753-755
    • Yan, Q.1    Elliott, J.2    Snider, W.D.3
  • 72
    • 0028854836 scopus 로고
    • In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
    • Yan Q., Matheson C., Lopez O. T. In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature. 373:1995;341-344.
    • (1995) Nature , vol.373 , pp. 341-344
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3
  • 73
    • 0027969192 scopus 로고
    • The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor
    • Yan Q., Matheson C., Lopez O., Miller J. The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor. J. Neurosci. 14:1994;5281-5291.
    • (1994) J. Neurosci. , vol.14 , pp. 5281-5291
    • Yan, Q.1    Matheson, C.2    Lopez, O.3    Miller, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.