-
1
-
-
0036523088
-
Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl
-
Anantharam V., Kitazawa M., Wagner J., Kaul S., and Kanthasamy A.G. Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl. J. Neurosci. 22 (2002) 1738-1751
-
(2002)
J. Neurosci.
, vol.22
, pp. 1738-1751
-
-
Anantharam, V.1
Kitazawa, M.2
Wagner, J.3
Kaul, S.4
Kanthasamy, A.G.5
-
2
-
-
0016170523
-
Studies on a murine form of spontaneous lower motor neuron degeneration - the wobbler (wa) mouse
-
Andrews J.M., Gardner M.B., Wolfgram F.J., Ellison G.W., Porter D.D., and Brandkamp W.W. Studies on a murine form of spontaneous lower motor neuron degeneration - the wobbler (wa) mouse. Am. J. Pathol. 76 (1974) 63-78
-
(1974)
Am. J. Pathol.
, vol.76
, pp. 63-78
-
-
Andrews, J.M.1
Gardner, M.B.2
Wolfgram, F.J.3
Ellison, G.W.4
Porter, D.D.5
Brandkamp, W.W.6
-
3
-
-
0035189072
-
Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels
-
Bendotti C., Tortarolo M., Suchak S.K., Calvaresi N., Carvelli L., Bastone A., Rizzi M., Rattray M., and Mennini T. Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels. J. Neurochem. 79 (2001) 737-746
-
(2001)
J. Neurochem.
, vol.79
, pp. 737-746
-
-
Bendotti, C.1
Tortarolo, M.2
Suchak, S.K.3
Calvaresi, N.4
Carvelli, L.5
Bastone, A.6
Rizzi, M.7
Rattray, M.8
Mennini, T.9
-
4
-
-
0020468038
-
Quantitative light and electron microscopic studies on the ventral roots of the wobbler mutant mouse
-
Biscoe T.J., and Lewkowicz S.J. Quantitative light and electron microscopic studies on the ventral roots of the wobbler mutant mouse. Q J. Exp. Physiol. 67 (1982) 543-555
-
(1982)
Q J. Exp. Physiol.
, vol.67
, pp. 543-555
-
-
Biscoe, T.J.1
Lewkowicz, S.J.2
-
5
-
-
0037087082
-
Motoneuron morphological alterations before and after the onset of the disease in the wobbler mouse
-
Blondet B., Carpentier G., Ait-Ikhlef A., Murawsky M., and Rieger F. Motoneuron morphological alterations before and after the onset of the disease in the wobbler mouse. Brain Res. 930 (2002) 53-57
-
(2002)
Brain Res.
, vol.930
, pp. 53-57
-
-
Blondet, B.1
Carpentier, G.2
Ait-Ikhlef, A.3
Murawsky, M.4
Rieger, F.5
-
6
-
-
0028142392
-
-
B.R. Brooks, El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors, J. Neurol. Sci. 124 (Suppl.) (1994) 96-107.
-
-
-
-
7
-
-
0043166646
-
Early mitochondrial dysfunction occurs in motor cortex and spinal cord at the onset of disease in the Wobbler mouse
-
Dave K.R., Bradley W.G., and Perez-Pinzon M.A. Early mitochondrial dysfunction occurs in motor cortex and spinal cord at the onset of disease in the Wobbler mouse. Exp. Neurol. 182 (2003) 412-420
-
(2003)
Exp. Neurol.
, vol.182
, pp. 412-420
-
-
Dave, K.R.1
Bradley, W.G.2
Perez-Pinzon, M.A.3
-
8
-
-
11844306671
-
Aberrant deltaPKC activation in the spinal cord of Wobbler mouse: a model of motor neuron disease
-
Dave K.R., Raval A.P., Purroy J., Kirkinezos I.G., Moraes C.T., Bradley W.G., and Perez-Pinzon M.A. Aberrant deltaPKC activation in the spinal cord of Wobbler mouse: a model of motor neuron disease. Neurobiol. Dis. 18 (2005) 126-133
-
(2005)
Neurobiol. Dis.
, vol.18
, pp. 126-133
-
-
Dave, K.R.1
Raval, A.P.2
Purroy, J.3
Kirkinezos, I.G.4
Moraes, C.T.5
Bradley, W.G.6
Perez-Pinzon, M.A.7
-
9
-
-
0014368955
-
An hereditary motor neurone disease with progressive denervation of muscle in the mouse: the mutant 'wobbler'
-
Duchen L.W., and Strich S.J. An hereditary motor neurone disease with progressive denervation of muscle in the mouse: the mutant 'wobbler'. J. Neurol. Neurosurg. Psychiatry 31 (1968) 535-542
-
(1968)
J. Neurol. Neurosurg. Psychiatry
, vol.31
, pp. 535-542
-
-
Duchen, L.W.1
Strich, S.J.2
-
10
-
-
34247880171
-
Transcription factor p53 in degenerating spinal cords
-
Eve D.J., Dennis J.S., and Citron B.A. Transcription factor p53 in degenerating spinal cords. Brain Res. 1150 (2007) 174-181
-
(2007)
Brain Res.
, vol.1150
, pp. 174-181
-
-
Eve, D.J.1
Dennis, J.S.2
Citron, B.A.3
-
11
-
-
34648870671
-
-
D. Falconer, Wobbler mouse, News Lett. 15 (1956) 23.
-
-
-
-
12
-
-
0345578686
-
Progesterone neuroprotection in the Wobbler mouse, a genetic model of spinal cord motor neuron disease
-
Gonzalez Deniselle M.C., Lopez-Costa J.J., Saavedra J.P., Pietranera L., Gonzalez S.L., Garay L., Guennoun R., Schumacher M., and De Nicola A.F. Progesterone neuroprotection in the Wobbler mouse, a genetic model of spinal cord motor neuron disease. Neurobiol. Dis. 11 (2002) 457-468
-
(2002)
Neurobiol. Dis.
, vol.11
, pp. 457-468
-
-
Gonzalez Deniselle, M.C.1
Lopez-Costa, J.J.2
Saavedra, J.P.3
Pietranera, L.4
Gonzalez, S.L.5
Garay, L.6
Guennoun, R.7
Schumacher, M.8
De Nicola, A.F.9
-
13
-
-
0035437866
-
Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis
-
Guegan C., Vila M., Rosoklija G., Hays A.P., and Przedborski S. Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis. J. Neurosci. 21 (2001) 6569-6576
-
(2001)
J. Neurosci.
, vol.21
, pp. 6569-6576
-
-
Guegan, C.1
Vila, M.2
Rosoklija, G.3
Hays, A.P.4
Przedborski, S.5
-
14
-
-
0037094335
-
Rapid and reproducible methods using fluorogold for labelling a subpopulation of cervical motoneurons: application in the wobbler mouse
-
Haenggeli C., and Kato A.C. Rapid and reproducible methods using fluorogold for labelling a subpopulation of cervical motoneurons: application in the wobbler mouse. J. Neurosci. Methods 116 (2002) 119-124
-
(2002)
J. Neurosci. Methods
, vol.116
, pp. 119-124
-
-
Haenggeli, C.1
Kato, A.C.2
-
15
-
-
0036062628
-
Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
-
Hensley K., Floyd R.A., Gordon B., Mou S., Pye Q.N., Stewart C., West M., and Williamson K. Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. J. Neurochem. 82 (2002) 365-374
-
(2002)
J. Neurochem.
, vol.82
, pp. 365-374
-
-
Hensley, K.1
Floyd, R.A.2
Gordon, B.3
Mou, S.4
Pye, Q.N.5
Stewart, C.6
West, M.7
Williamson, K.8
-
16
-
-
0021367128
-
Species-specific second antibodies reduce spurious staining in immunocytochemistry
-
Houser C.R., Barber R.P., Crawford G.D., Matthews D.A., Phelps P.E., Salvaterra P.M., and Vaughn J.E. Species-specific second antibodies reduce spurious staining in immunocytochemistry. J. Histochem. Cytochem. 32 (1984) 395-402
-
(1984)
J. Histochem. Cytochem.
, vol.32
, pp. 395-402
-
-
Houser, C.R.1
Barber, R.P.2
Crawford, G.D.3
Matthews, D.A.4
Phelps, P.E.5
Salvaterra, P.M.6
Vaughn, J.E.7
-
17
-
-
0025727137
-
Changes in sizes of cortical and lower motor neurons in amyotrophic lateral sclerosis
-
Kiernan J.A., and Hudson A.J. Changes in sizes of cortical and lower motor neurons in amyotrophic lateral sclerosis. Brain 114 Pt 2 (1991) 843-853
-
(1991)
Brain
, vol.114
, Issue.PART 2
, pp. 843-853
-
-
Kiernan, J.A.1
Hudson, A.J.2
-
18
-
-
18844367752
-
Characterization of the human GARP (Golgi associated retrograde protein) complex
-
Liewen H., Meinhold-Heerlein I., Oliveira V., Schwarzenbacher R., Luo G., Wadle A., Jung M., Pfreundschuh M., and Stenner-Liewen F. Characterization of the human GARP (Golgi associated retrograde protein) complex. Exp. Cell Res. 306 (2005) 24-34
-
(2005)
Exp. Cell Res.
, vol.306
, pp. 24-34
-
-
Liewen, H.1
Meinhold-Heerlein, I.2
Oliveira, V.3
Schwarzenbacher, R.4
Luo, G.5
Wadle, A.6
Jung, M.7
Pfreundschuh, M.8
Stenner-Liewen, F.9
-
19
-
-
3042551352
-
Excitotoxicity in amyotrophic lateral sclerosis: selective vulnerability of motor neurons
-
Ferrarese C., and Beal M.F. (Eds), Kluwer Academic Publishers
-
Mennini T., and Bendotti C. Excitotoxicity in amyotrophic lateral sclerosis: selective vulnerability of motor neurons. In: Ferrarese C., and Beal M.F. (Eds). Excitotoxicity in Neurological Diseases. New Therapeutic Challenge (2004), Kluwer Academic Publishers 217-228
-
(2004)
Excitotoxicity in Neurological Diseases. New Therapeutic Challenge
, pp. 217-228
-
-
Mennini, T.1
Bendotti, C.2
-
20
-
-
0032863462
-
Lack of apoptosis in mice with ALS
-
Migheli A., Atzori C., Piva R., Tortarolo M., Girelli M., Schiffer D., and Bendotti C. Lack of apoptosis in mice with ALS. Nat. Med. 5 (1999) 966-967
-
(1999)
Nat. Med.
, vol.5
, pp. 966-967
-
-
Migheli, A.1
Atzori, C.2
Piva, R.3
Tortarolo, M.4
Girelli, M.5
Schiffer, D.6
Bendotti, C.7
-
21
-
-
0030700577
-
Diverse cell death pathways result from a single missense mutation in weaver mouse
-
Migheli A., Piva R., Wei J., Attanasio A., Casolino S., Hodes M.E., Dlouhy S.R., Bayer S.A., and Ghetti B. Diverse cell death pathways result from a single missense mutation in weaver mouse. Am. J. Pathol. 151 (1997) 1629-1638
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1629-1638
-
-
Migheli, A.1
Piva, R.2
Wei, J.3
Attanasio, A.4
Casolino, S.5
Hodes, M.E.6
Dlouhy, S.R.7
Bayer, S.A.8
Ghetti, B.9
-
22
-
-
0020429617
-
Murine motor neuron disease (the wobbler mouse): degeneration and regeneration of the lower motor neuron
-
Mitsumoto H., and Bradley W.G. Murine motor neuron disease (the wobbler mouse): degeneration and regeneration of the lower motor neuron. Brain 105 Pt 4 (1982) 811-834
-
(1982)
Brain
, vol.105
, Issue.PART 4
, pp. 811-834
-
-
Mitsumoto, H.1
Bradley, W.G.2
-
24
-
-
3242703300
-
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria
-
Pasinelli P., Belford M.E., Lennon N., Bacskai B.J., Hyman B.T., Trotti D., and Brown Jr. R.H. Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria. Neuron 43 (2004) 19-30
-
(2004)
Neuron
, vol.43
, pp. 19-30
-
-
Pasinelli, P.1
Belford, M.E.2
Lennon, N.3
Bacskai, B.J.4
Hyman, B.T.5
Trotti, D.6
Brown Jr., R.H.7
-
25
-
-
0029890292
-
Early upregulation of medium neurofilament gene expression in developing spinal cord of the wobbler mouse mutant
-
Pernas-Alonso R., Schaffner A.E., Perrone-Capano C., Orlando A., Morelli F., Hansen C.T., Barker J.L., Esposito B., Cacucci F., and di Porzio U. Early upregulation of medium neurofilament gene expression in developing spinal cord of the wobbler mouse mutant. Brain Res. Mol. Brain Res. 38 (1996) 267-275
-
(1996)
Brain Res. Mol. Brain Res.
, vol.38
, pp. 267-275
-
-
Pernas-Alonso, R.1
Schaffner, A.E.2
Perrone-Capano, C.3
Orlando, A.4
Morelli, F.5
Hansen, C.T.6
Barker, J.L.7
Esposito, B.8
Cacucci, F.9
di Porzio, U.10
-
26
-
-
0031080386
-
TRPM-2 expression and tunel staining in neurodegenerative diseases: studies in wobbler and rd mice
-
Popper P., Farber D.B., Micevych P.E., Minoofar K., and Bronstein J.M. TRPM-2 expression and tunel staining in neurodegenerative diseases: studies in wobbler and rd mice. Exp. Neurol. 143 (1997) 246-254
-
(1997)
Exp. Neurol.
, vol.143
, pp. 246-254
-
-
Popper, P.1
Farber, D.B.2
Micevych, P.E.3
Minoofar, K.4
Bronstein, J.M.5
-
27
-
-
0037068836
-
Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations
-
Raoul C., Estevez A.G., Nishimune H., Cleveland D.W., deLapeyriere O., Henderson C.E., Haase G., and Pettmann B. Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron 35 (2002) 1067-1083
-
(2002)
Neuron
, vol.35
, pp. 1067-1083
-
-
Raoul, C.1
Estevez, A.G.2
Nishimune, H.3
Cleveland, D.W.4
deLapeyriere, O.5
Henderson, C.E.6
Haase, G.7
Pettmann, B.8
-
28
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., Donaldson D., Goto J., O'Regan J.P., Goto J., and Deng H.X. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362 (1993) 59-62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Goto, J.10
Deng, H.X.11
-
29
-
-
0031823351
-
Quantitative reverse transcriptase PCR to gauge increased protease-active receptor 1 (PAR-1) mRNA copy numbers in the Wobbler mutant mouse
-
Salcedo R.M., Festoff B.W., and Citron B.A. Quantitative reverse transcriptase PCR to gauge increased protease-active receptor 1 (PAR-1) mRNA copy numbers in the Wobbler mutant mouse. J. Mol. Neurosci. 10 (1998) 113-119
-
(1998)
J. Mol. Neurosci.
, vol.10
, pp. 113-119
-
-
Salcedo, R.M.1
Festoff, B.W.2
Citron, B.A.3
-
30
-
-
5144219600
-
Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease
-
Santoro B., Bigini P., Levandis G., Nobile V., Biggiogera M., Botti F., Mennini T., and Curti D. Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease. Neurobiol. Dis. 17 (2004) 349-357
-
(2004)
Neurobiol. Dis.
, vol.17
, pp. 349-357
-
-
Santoro, B.1
Bigini, P.2
Levandis, G.3
Nobile, V.4
Biggiogera, M.5
Botti, F.6
Mennini, T.7
Curti, D.8
-
31
-
-
27644469489
-
Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse
-
Schmitt-John T., Drepper C., Mussmann A., Hahn P., Kuhlmann M., Thiel C., Hafner M., Lengeling A., Heimann P., Jones J.M., Meisler M.H., and Jockusch H. Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse. Nat. Genet. 37 (2005) 1213-1215
-
(2005)
Nat. Genet.
, vol.37
, pp. 1213-1215
-
-
Schmitt-John, T.1
Drepper, C.2
Mussmann, A.3
Hahn, P.4
Kuhlmann, M.5
Thiel, C.6
Hafner, M.7
Lengeling, A.8
Heimann, P.9
Jones, J.M.10
Meisler, M.H.11
Jockusch, H.12
-
32
-
-
0342657086
-
Motor neurons are rich in non-phosphorylated neurofilaments: cross-species comparison and alterations in ALS
-
Tsang Y.M., Chiong F., Kuznetsov D., Kasarskis E., and Geula C. Motor neurons are rich in non-phosphorylated neurofilaments: cross-species comparison and alterations in ALS. Brain Res. 861 (2000) 45-58
-
(2000)
Brain Res.
, vol.861
, pp. 45-58
-
-
Tsang, Y.M.1
Chiong, F.2
Kuznetsov, D.3
Kasarskis, E.4
Geula, C.5
-
33
-
-
32244441514
-
Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS
-
Veglianese P., Lo Coco D., Bao Cutrona M., Magnoni R., Pennacchini D., Pozzi B., Gowing G., Julien J.P., Tortarolo M., and Bendotti C. Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS. Mol. Cell. Neurosci. 31 (2006) 218-231
-
(2006)
Mol. Cell. Neurosci.
, vol.31
, pp. 218-231
-
-
Veglianese, P.1
Lo Coco, D.2
Bao Cutrona, M.3
Magnoni, R.4
Pennacchini, D.5
Pozzi, B.6
Gowing, G.7
Julien, J.P.8
Tortarolo, M.9
Bendotti, C.10
-
34
-
-
0032810012
-
ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation
-
Volbracht C., Leist M., and Nicotera P. ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation. Mol. Med. 5 (1999) 477-489
-
(1999)
Mol. Med.
, vol.5
, pp. 477-489
-
-
Volbracht, C.1
Leist, M.2
Nicotera, P.3
-
35
-
-
85047699103
-
Is motoneuronal cell death in amyotrophic lateral sclerosis apoptosis?
-
Yamazaki M., Esumi E., and Nakano I. Is motoneuronal cell death in amyotrophic lateral sclerosis apoptosis?. Neuropathology 25 (2005) 381-387
-
(2005)
Neuropathology
, vol.25
, pp. 381-387
-
-
Yamazaki, M.1
Esumi, E.2
Nakano, I.3
|