-
1
-
-
34548694728
-
Advances in Alzheimer therapy: Development of innovative new strategies
-
Greig, N.H.; Giacobini, E.; Lahiri, D.K. Advances in Alzheimer therapy: development of innovative new strategies. Curr. Alzheimer Res., 2007, 4(4), 336-339.
-
(2007)
Curr. Alzheimer Res
, vol.4
, Issue.4
, pp. 336-339
-
-
Greig, N.H.1
Giacobini, E.2
Lahiri, D.K.3
-
2
-
-
43649099862
-
Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: An open-label, crossover, single-centre study
-
Shua-Haim, J.; Smith, J.; Picard, F.; Sedek, G.; Athalye, S.; Pommier, F.; Lefèvre, G. Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: an open-label, crossover, single-centre study. Clin. Drug Invest., 2008, 6, 361-374.
-
(2008)
Clin. Drug Invest
, vol.6
, pp. 361-374
-
-
Shua-Haim, J.1
Smith, J.2
Picard, F.3
Sedek, G.4
Athalye, S.5
Pommier, F.6
Lefèvre, G.7
-
3
-
-
0000545124
-
Structure-activity relationships of acetylcholinesterase inhibitors: Donepezil hydrochloride for the treatment of Alzheimer's Disease
-
Sugimoto, H. Structure-activity relationships of acetylcholinesterase inhibitors: Donepezil hydrochloride for the treatment of Alzheimer's Disease. Pure Appl. Chem., 1999, 71, 2031-2037.
-
(1999)
Pure Appl. Chem
, vol.71
, pp. 2031-2037
-
-
Sugimoto, H.1
-
4
-
-
9644301088
-
Novel neuronal targets for the acetylcholinesterase inhibitor donepezil
-
Sortino, M.A.; Frasca, G.; Chisari, M.; Platania, P.; Chiechio, S.; Vancheri, C.; Copani, A.; Canonico, P.L. Novel neuronal targets for the acetylcholinesterase inhibitor donepezil. Neuropharmacology, 2004, 47, 1198-1204.
-
(2004)
Neuropharmacology
, vol.47
, pp. 1198-1204
-
-
Sortino, M.A.1
Frasca, G.2
Chisari, M.3
Platania, P.4
Chiechio, S.5
Vancheri, C.6
Copani, A.7
Canonico, P.L.8
-
5
-
-
0034664203
-
Kinetics of human acetylcholinesterase inhibition by the novel experimental alzheimer therapeutic agent, tolserine
-
Kamal, M.A.; Greig, N.H.; Alhomida, A.S.; Al-Jafari, A.A. Kinetics of human acetylcholinesterase inhibition by the novel experimental alzheimer therapeutic agent, tolserine. Biochem. Pharmacol. 2000, 60 (4), 561-570.
-
(2000)
Biochem. Pharmacol
, vol.60
, Issue.4
, pp. 561-570
-
-
Kamal, M.A.1
Greig, N.H.2
Alhomida, A.S.3
Al-Jafari, A.A.4
-
6
-
-
33644633856
-
A new, simple and economical approach to analyse the inhibition kinetics of acetylcholinesterase using tolserine
-
Kamal, M.A.; Greig, N.H.; Al-Jafari, A.A. A new, simple and economical approach to analyse the inhibition kinetics of acetylcholinesterase using tolserine. Em. Med. J., 2002, 20(3), 333-337.
-
(2002)
Em. Med. J
, vol.20
, Issue.3
, pp. 333-337
-
-
Kamal, M.A.1
Greig, N.H.2
Al-Jafari, A.A.3
-
7
-
-
0033787766
-
Brain acetylcholinesterase inhibition kinetics of two experimental Alzheimer's disease drugs, phenserine and tolserine, in the rat
-
Al-Jafari, A.A.; Kamal, M.A.; Alhomida, A.S.; Greig, N.H. Brain acetylcholinesterase inhibition kinetics of two experimental Alzheimer's disease drugs, phenserine and tolserine, in the rat. J. Biochem. Mol. Biol. Biophys., 2000, 4, 323-335.
-
(2000)
J. Biochem. Mol. Biol. Biophys
, vol.4
, pp. 323-335
-
-
Al-Jafari, A.A.1
Kamal, M.A.2
Alhomida, A.S.3
Greig, N.H.4
-
8
-
-
33748742887
-
Neurine, an acetylcholine autolysis product, elevates secreted amyloidbeta protein precursor and amyloid-beta peptide levels, and lowers neuronal cell viability in culture: A role in Alzheimer's disease?
-
Tweedie, D.; Brossi, A.; Chen, D.M.; Ge, Y-W.; Bailey, J.; Yu, Q-S.; Kamal, M.A.; Sambamurti, K.; Lahiri, D.K.; Greig, N.H. Neurine, an acetylcholine autolysis product, elevates secreted amyloidbeta protein precursor and amyloid-beta peptide levels, and lowers neuronal cell viability in culture: A role in Alzheimer's disease? J. Alzheimer's Dis., 2006, 10, 9-16.
-
(2006)
J. Alzheimer's Dis
, vol.10
, pp. 9-16
-
-
Tweedie, D.1
Brossi, A.2
Chen, D.M.3
Ge, Y.-W.4
Bailey, J.5
Yu, Q.-S.6
Kamal, M.A.7
Sambamurti, K.8
Lahiri, D.K.9
Greig, N.H.10
-
9
-
-
33748751561
-
Kinetics of human serum butyrylcholinesterase and its inhibition by a novel experimental Alzheimer therapeutic, bisnorcymserine
-
Kamal, M.A; Yu, Q-S.; Holloway, H.W.; Tweedie, D.; Klein, P.; Greig, N.H. Kinetics of human serum butyrylcholinesterase and its inhibition by a novel experimental Alzheimer therapeutic, bisnorcymserine. J. Alzhemiers. Dis., 2006, 10, 43-51.
-
(2006)
J. Alzhemiers. Dis
, vol.10
, pp. 43-51
-
-
Kamal, M.A.1
Yu, Q.-S.2
Holloway, H.W.3
Tweedie, D.4
Klein, P.5
Greig, N.H.6
-
10
-
-
33644613485
-
Kinetic analysis of the inhibition of human butyrylcholinesterase with cymserine
-
Kamal, M.A.; Al-Jafari, A.A.; Yu, Q-S; Greig, N.H. Kinetic analysis of the inhibition of human butyrylcholinesterase with cymserine. Biochem. Biophys. Acta, 2006, 1760, 200-206.
-
(2006)
Biochem. Biophys. Acta
, vol.1760
, pp. 200-206
-
-
Kamal, M.A.1
Al-Jafari, A.A.2
Yu, Q.-S.3
Greig, N.H.4
-
11
-
-
41049107851
-
Kinetics of human serum butyrylcholinesterase inhibition by a novel experimental alzheimer therapeutic; dihydrobenzodioxepine cymserine
-
Kamal, M.A.; Klein, P.; Luo, W.; Li, Y.; Holloway, H.W.; Tweedie, D.; Greig, N.H. Kinetics of human serum butyrylcholinesterase inhibition by a novel experimental alzheimer therapeutic; dihydrobenzodioxepine cymserine. Neurochem. Res., 2008, 33, 745-753.
-
(2008)
Neurochem. Res
, vol.33
, pp. 745-753
-
-
Kamal, M.A.1
Klein, P.2
Luo, W.3
Li, Y.4
Holloway, H.W.5
Tweedie, D.6
Greig, N.H.7
-
12
-
-
44949096480
-
-
Kamal, M.A; Qu, X.; Yu, Q-S; Tweedie, D.; Holloway, H.W.; Li, Y.; Tan, Y.; Greig, N.H. Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis. J. Neural Trans., 2008, 115, 889-898.
-
Kamal, M.A; Qu, X.; Yu, Q-S; Tweedie, D.; Holloway, H.W.; Li, Y.; Tan, Y.; Greig, N.H. Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis. J. Neural Trans., 2008, 115, 889-898.
-
-
-
-
13
-
-
37349104938
-
Disability in Alzheimer's disease: Causes, consequences, and economic considerations
-
Demakis, G.J. Disability in Alzheimer's disease: causes, consequences, and economic considerations. J. Health Hum. Serv. Adm., 2007, 30, 292-305.
-
(2007)
J. Health Hum. Serv. Adm
, vol.30
, pp. 292-305
-
-
Demakis, G.J.1
-
14
-
-
36549083642
-
Neuroinflammation: Implications for the pathogenesis and molecular diagnosis of Alzheimer's disease
-
Rojo, L.E.; Fernández, J.A.; Maccioni, A.A.; Jimenez, J.M.; Maccioni, R.B. Neuroinflammation: implications for the pathogenesis and molecular diagnosis of Alzheimer's disease. Arch. Med. Res., 2008, 39, 1-16.
-
(2008)
Arch. Med. Res
, vol.39
, pp. 1-16
-
-
Rojo, L.E.1
Fernández, J.A.2
Maccioni, A.A.3
Jimenez, J.M.4
Maccioni, R.B.5
-
15
-
-
38449107280
-
-
Swerdlow, R.H. Pathogenesis of Alzheimer's disease. Clin Interv. Aging, 2007, 2, 347-59.
-
Swerdlow, R.H. Pathogenesis of Alzheimer's disease. Clin Interv. Aging, 2007, 2, 347-59.
-
-
-
-
16
-
-
34547380204
-
-
Rogers, J.; Mastroeni, D.; Leonard, B.; Joyce, J.; Grover, A. Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder? Int. Rev. Neurobiol., 2007, 82, 235-246
-
Rogers, J.; Mastroeni, D.; Leonard, B.; Joyce, J.; Grover, A. Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder? Int. Rev. Neurobiol., 2007, 82, 235-246
-
-
-
-
17
-
-
33847613885
-
Inflammatory processes in Alzheimer's disease
-
Heneka, M.T.; O'Banion, M.K. Inflammatory processes in Alzheimer's disease. J. Neuroimmunol., 2007, 184, 69-91.
-
(2007)
J. Neuroimmunol
, vol.184
, pp. 69-91
-
-
Heneka, M.T.1
O'Banion, M.K.2
-
18
-
-
40449137990
-
Neuroinflammation in plaque and vascular beta-amyloid disorders: Clinical and therapeutic implications
-
Eikelenboom, P.; Veerhuis, R.; Familian, A.; Hoozemans, J.J.; van Gool, W.A.; Rozemuller, A.J. Neuroinflammation in plaque and vascular beta-amyloid disorders: clinical and therapeutic implications. Neurodegener. Dis., 2008, 5, 190-193.
-
(2008)
Neurodegener. Dis
, vol.5
, pp. 190-193
-
-
Eikelenboom, P.1
Veerhuis, R.2
Familian, A.3
Hoozemans, J.J.4
van Gool, W.A.5
Rozemuller, A.J.6
-
19
-
-
0025899041
-
Amyloid deposition as the central event in the. etiology of Alzheimer's disease
-
Hard, J.; Allsop, D. Amyloid deposition as the central event in the. etiology of Alzheimer's disease. Trends Pharmacol. Sci., 1991, 12, 383-388.
-
(1991)
Trends Pharmacol. Sci
, vol.12
, pp. 383-388
-
-
Hard, J.1
Allsop, D.2
-
20
-
-
0028180518
-
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease
-
Hensley, K.; Carney, J.M.; Mattson, M.P.; Aksenova, M.; Harris, M.; Wu, J.F.; Floyd, R.A.; Butterfield, D.A. A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. Proc. Natl. Acad. Sci. USA, 1994, 91, 3270-3274.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3270-3274
-
-
Hensley, K.1
Carney, J.M.2
Mattson, M.P.3
Aksenova, M.4
Harris, M.5
Wu, J.F.6
Floyd, R.A.7
Butterfield, D.A.8
-
21
-
-
33846957719
-
Neuronal damage in brain inflammation
-
Aktas, O.; Ullrich, O.; Infante-Duarte, C.; Nitsch, R.; Zipp, F. Neuronal damage in brain inflammation. Arch. Neurol., 2007, 64, 185-189.
-
(2007)
Arch. Neurol
, vol.64
, pp. 185-189
-
-
Aktas, O.1
Ullrich, O.2
Infante-Duarte, C.3
Nitsch, R.4
Zipp, F.5
-
22
-
-
0031038918
-
Alzheimer's disease. Genotypes, phenotype and treatments
-
Selkoe, D.J. Alzheimer's disease. Genotypes, phenotype and treatments. Science, 1997, 275, 630-631.
-
(1997)
Science
, vol.275
, pp. 630-631
-
-
Selkoe, D.J.1
-
23
-
-
0024406110
-
The pathogenesis and progression of the pathological changes of Alzheimer's disease
-
Mann, D.M. The pathogenesis and progression of the pathological changes of Alzheimer's disease. Ann. Med., 1989, 21, 133-136
-
(1989)
Ann. Med
, vol.21
, pp. 133-136
-
-
Mann, D.M.1
-
24
-
-
0030610645
-
Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E
-
Barger, S.W.; Harmon, A.D. Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature, 1997, 388, 878-881.
-
(1997)
Nature
, vol.388
, pp. 878-881
-
-
Barger, S.W.1
Harmon, A.D.2
-
25
-
-
0029896354
-
Mechanisms of neuronal degeneration in Alzheimer's disease
-
Yankner, B.A. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron., 1996, 16, 921-32.
-
(1996)
Neuron
, vol.16
, pp. 921-932
-
-
Yankner, B.A.1
-
26
-
-
47849121512
-
The damage signals hypothesis of Alzheimer's disease pathogenesis
-
Fernández, J.A.; Rojo, L.; Kuljis, R.O.; Maccioni, R.B.: The damage signals hypothesis of Alzheimer's disease pathogenesis. J. Alzheimers Dis., 2008, 14, 329-333.
-
(2008)
J. Alzheimers Dis
, vol.14
, pp. 329-333
-
-
Fernández, J.A.1
Rojo, L.2
Kuljis, R.O.3
Maccioni, R.B.4
-
27
-
-
0036451888
-
Non-cholinergic strategies for treating and preventing Alzheimer's disease
-
Doraiswamy, P.M. Non-cholinergic strategies for treating and preventing Alzheimer's disease. CNS Drugs, 2002, 16, 811-824.
-
(2002)
CNS Drugs
, vol.16
, pp. 811-824
-
-
Doraiswamy, P.M.1
-
28
-
-
36749062430
-
Molecular and cellular mechanisms for Alzheimer's disease: Understanding APP metabolism
-
Zhang, Y.W.; Xu, H. Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism. Curr. Mol. Med., 2007, 7, 687-696.
-
(2007)
Curr. Mol. Med
, vol.7
, pp. 687-696
-
-
Zhang, Y.W.1
Xu, H.2
-
29
-
-
0023487911
-
Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease
-
Bondareff, W.; Mountjoy, C.Q.; Roth, M.; Rossor, M.N.; Iversen, L.L.; Reynolds, G.P.; Hauser, D.L. Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease. Alzheimer Dis. Assoc. Disord., 1987, 1, 256-262.
-
(1987)
Alzheimer Dis. Assoc. Disord
, vol.1
, pp. 256-262
-
-
Bondareff, W.1
Mountjoy, C.Q.2
Roth, M.3
Rossor, M.N.4
Iversen, L.L.5
Reynolds, G.P.6
Hauser, D.L.7
-
30
-
-
34250698844
-
Glutamate-glutamine cycling in Alzheimer's disease
-
Walton, H.S.; Dodd, P.R. Glutamate-glutamine cycling in Alzheimer's disease. Neurochem Int., 2007, 50, 1052-1066.
-
(2007)
Neurochem Int
, vol.50
, pp. 1052-1066
-
-
Walton, H.S.1
Dodd, P.R.2
-
31
-
-
0021646405
-
Neurotransmitter specific alterations in dementing disorders: Insights from animal models
-
Coyle, J.T.; Singer, H.; McKinney, M.; Price, D. Neurotransmitter specific alterations in dementing disorders: insights from animal models. J. Psychiatr. Res., 1984, 18, 501-512.
-
(1984)
J. Psychiatr. Res
, vol.18
, pp. 501-512
-
-
Coyle, J.T.1
Singer, H.2
McKinney, M.3
Price, D.4
-
32
-
-
33748451468
-
Oxidative stress, mitochondrial dysfunction, and stress signaling in Alzheimer's disease
-
Onyango, I.G.; Khan, S.M. Oxidative stress, mitochondrial dysfunction, and stress signaling in Alzheimer's disease. Curr. Alzheimer. Res., 2006, 3, 339-349.
-
(2006)
Curr. Alzheimer. Res
, vol.3
, pp. 339-349
-
-
Onyango, I.G.1
Khan, S.M.2
-
33
-
-
20444399515
-
Stress in the brain: Novel cellular mechanisms of injury linked to Alzheimer's disease
-
Chong, Z.Z.; Li, F.; Maiese, K. Stress in the brain: novel cellular mechanisms of injury linked to Alzheimer's disease. Brain. Res. Brain Res. Rev., 2005, 49, 1-21.
-
(2005)
Brain. Res. Brain Res. Rev
, vol.49
, pp. 1-21
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
34
-
-
37549056224
-
Evidence for the role of luteinizing hormone in Alzheimer disease
-
Webber, K.M.; Casadesus, G.; Bowen, R.L.; Perry. G.; Smith, M.A. Evidence for the role of luteinizing hormone in Alzheimer disease. Endocr. Metab. Immune Disord. Drug Targets, 2007, 7, 300-303.
-
(2007)
Endocr. Metab. Immune Disord. Drug Targets
, vol.7
, pp. 300-303
-
-
Webber, K.M.1
Casadesus, G.2
Bowen, R.L.3
Perry, G.4
Smith, M.A.5
-
35
-
-
29744453687
-
Amyloid, cholinesterase, melatonin, and metals and their roles in aging and neurodegenerative diseases
-
Lahiri, D.K.; Chen, D.M.; Lahiri, P.; Bondy, S.; Greig, N.H. Amyloid, cholinesterase, melatonin, and metals and their roles in aging and neurodegenerative diseases. Ann. N. Y Acad. Sci., 2005, 1056, 430-449.
-
(2005)
Ann. N. Y Acad. Sci
, vol.1056
, pp. 430-449
-
-
Lahiri, D.K.1
Chen, D.M.2
Lahiri, P.3
Bondy, S.4
Greig, N.H.5
-
36
-
-
42149097165
-
Current Alzheimer Research': Update on lipids, estrogen, neurotrophins and their roles in neurodegeneration
-
Lahiri, D.K. Current Alzheimer Research': update on lipids, estrogen, neurotrophins and their roles in neurodegeneration. Curr. Alzheimer Res., 2008, 5, 1-3.
-
(2008)
Curr. Alzheimer Res
, vol.5
, pp. 1-3
-
-
Lahiri, D.K.1
-
37
-
-
33746489936
-
Towards a unifying hypothesis of Alzheimer's disease: Cholinergic system linked to plaques, tangles and neuroinflammation
-
Sivaprakasam, K. Towards a unifying hypothesis of Alzheimer's disease: cholinergic system linked to plaques, tangles and neuroinflammation. Curr. Med. Chem., 2006, 13, 2179-2188.
-
(2006)
Curr. Med. Chem
, vol.13
, pp. 2179-2188
-
-
Sivaprakasam, K.1
-
38
-
-
33646939813
-
Anticholinesterasics in the treatment of cognitive impairment in multiple sclerosis
-
Porcel, J.; Montalban, X. Anticholinesterasics in the treatment of cognitive impairment in multiple sclerosis. J. Neurol. Sci., 2006, 245, 177-181.
-
(2006)
J. Neurol. Sci
, vol.245
, pp. 177-181
-
-
Porcel, J.1
Montalban, X.2
-
39
-
-
0032910197
-
The cholinergic hypothesis of Alzheimer's disease: A review of progress
-
Francis, P.T.; Palmer, A.M.; Snape, M.; Wilcock, G.K. The cholinergic hypothesis of Alzheimer's disease: a review of progress. J. Neurol. Neurosurg. Psychiatry, 1999, 66, 137-147.
-
(1999)
J. Neurol. Neurosurg. Psychiatry
, vol.66
, pp. 137-147
-
-
Francis, P.T.1
Palmer, A.M.2
Snape, M.3
Wilcock, G.K.4
-
40
-
-
35748978820
-
Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment
-
Musia, A.; Bajda, M.; Malawska, B. Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment. Curr. Med. Chem., 2007, 14, 2654-2679.
-
(2007)
Curr. Med. Chem
, vol.14
, pp. 2654-2679
-
-
Musia, A.1
Bajda, M.2
Malawska, B.3
-
42
-
-
84880185810
-
Inflammation, anti-inflammatory agents and Alzheimer disease: The last 12 years
-
McGeer, P.L.; Rogers, J.; McGeer, E.G. Inflammation, anti-inflammatory agents and Alzheimer disease: the last 12 years. J. Alzheimers Dis., 2006, 9, 271-276.
-
(2006)
J. Alzheimers Dis
, vol.9
, pp. 271-276
-
-
McGeer, P.L.1
Rogers, J.2
McGeer, E.G.3
-
43
-
-
0036685522
-
Inflammation in neurodegenerative disease-a double-edged sword
-
Wyss-Coray, T.; Mucke, L. Inflammation in neurodegenerative disease-a double-edged sword. Neuron, 2002, 35419-35433.
-
(2002)
Neuron
, pp. 35419-35433
-
-
Wyss-Coray, T.1
Mucke, L.2
-
44
-
-
47849127085
-
Inflammatory aspects of Alzheimer disease and other neurodegenerative disorders
-
Schwab, C.; McGeer, P.L. Inflammatory aspects of Alzheimer disease and other neurodegenerative disorders. J. Alzheimers Dis., 2008, 13, 359-369.
-
(2008)
J. Alzheimers Dis
, vol.13
, pp. 359-369
-
-
Schwab, C.1
McGeer, P.L.2
-
45
-
-
0034651101
-
Inflammatory mechanisms in Alzheimer's disease: Inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists
-
Combs, C.K.; Johnson, D.E.; Karlo, J.C.; Cannady, S.B.; Landreth, G.E. Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. J. Neurosci., 2000, 20, 558-567.
-
(2000)
J. Neurosci
, vol.20
, pp. 558-567
-
-
Combs, C.K.1
Johnson, D.E.2
Karlo, J.C.3
Cannady, S.B.4
Landreth, G.E.5
-
46
-
-
0035936009
-
Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease?
-
Breitner, J.C.; Zandi, P.P. Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease? N. Engl. J. Med., 2001, 345, 1567-1568.
-
(2001)
N. Engl. J. Med
, vol.345
, pp. 1567-1568
-
-
Breitner, J.C.1
Zandi, P.P.2
-
47
-
-
44949084672
-
Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology
-
Arvanitakis, Z.; Grodstein, F.; Bienias, J.L.; Schneider, J.A.; Wilson, R.S.; Kelly, J.F.; Evans, D.A.; Bennett, D.A. Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology. Neurology, 2008, 70, 2219-2225.
-
(2008)
Neurology
, vol.70
, pp. 2219-2225
-
-
Arvanitakis, Z.1
Grodstein, F.2
Bienias, J.L.3
Schneider, J.A.4
Wilson, R.S.5
Kelly, J.F.6
Evans, D.A.7
Bennett, D.A.8
-
48
-
-
43149102747
-
Protective effects of NSAIDs on the development of Alzheimer disease
-
Vlad, S.C.; Miller, D.R.; Kowall, N.W.; Felson, D.T. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology, 2008, 70, 1672-1677.
-
(2008)
Neurology
, vol.70
, pp. 1672-1677
-
-
Vlad, S.C.1
Miller, D.R.2
Kowall, N.W.3
Felson, D.T.4
-
49
-
-
43249120645
-
The inflammatory hypothesis of Alzheimer disease: Dead or alive?
-
Aisen, P.S. The inflammatory hypothesis of Alzheimer disease: dead or alive? Alzheimer Dis. Assoc. Disord., 2008, 22, 4-5.
-
(2008)
Alzheimer Dis. Assoc. Disord
, vol.22
, pp. 4-5
-
-
Aisen, P.S.1
-
50
-
-
0035831189
-
Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology
-
Apelt, R.; Schliebs, J. Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology. Brain Res., 2001, 894, 21-30.
-
(2001)
Brain Res
, vol.894
, pp. 21-30
-
-
Apelt, R.1
Schliebs, J.2
-
51
-
-
14944367845
-
Microglia as a potential bridge between the amyloid beta-peptide and tau
-
Kitazawa, M.; Yamasaki, T.R.; LaFerla, F.M. Microglia as a potential bridge between the amyloid beta-peptide and tau. Ann. N.Y. Acad. Sci., 2004, 1035, 85-103.
-
(2004)
Ann. N.Y. Acad. Sci
, vol.1035
, pp. 85-103
-
-
Kitazawa, M.1
Yamasaki, T.R.2
LaFerla, F.M.3
-
52
-
-
28444435458
-
Inflammation, the complement system and the diseases of aging
-
McGeer, E.G.; Klegeris, A.; McGeer, P.L. Inflammation, the complement system and the diseases of aging. Neurobiol. Aging, 2005, 26, 997.
-
(2005)
Neurobiol. Aging
, vol.26
, pp. 997
-
-
McGeer, E.G.1
Klegeris, A.2
McGeer, P.L.3
-
53
-
-
0037101616
-
Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis
-
Guo, J.T.; Yu, J.; Grass, D.; de Beer, F.C.; Kindy, M.S. Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis. J. Neurosci., 2002, 22, 5900-5909.
-
(2002)
J. Neurosci
, vol.22
, pp. 5900-5909
-
-
Guo, J.T.1
Yu, J.2
Grass, D.3
de Beer, F.C.4
Kindy, M.S.5
-
54
-
-
25444505871
-
Investigations with cultured human microglia on pathogenic mechanisms of Alzheimer's disease and other neurodegenerative diseases
-
Walker, D.G.; Lue, L.F. Investigations with cultured human microglia on pathogenic mechanisms of Alzheimer's disease and other neurodegenerative diseases. J. Neurosci. Res., 2005, 8, 412-425.
-
(2005)
J. Neurosci. Res
, vol.8
, pp. 412-425
-
-
Walker, D.G.1
Lue, L.F.2
-
55
-
-
35148863154
-
Inflammatory changes parallel the early stages of Alzheimer disease
-
Parachikova, A.; Agadjanyan, M.G.; Cribbs, D.H.; Blurton-Jones, M.; Perreau, V.; Rogers, J.; Beach, T.G.; Cotman, C.W. Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiol. Aging, 2007, 28, 1821-1833.
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 1821-1833
-
-
Parachikova, A.1
Agadjanyan, M.G.2
Cribbs, D.H.3
Blurton-Jones, M.4
Perreau, V.5
Rogers, J.6
Beach, T.G.7
Cotman, C.W.8
-
56
-
-
20444364844
-
Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective
-
Butovsky, O.; Talpalar, A.E.; Ben-Yaakov, K.; Schwartz, M. Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective. Mol. Cell Neurosci., 2005, 29, 381-393.
-
(2005)
Mol. Cell Neurosci
, vol.29
, pp. 381-393
-
-
Butovsky, O.1
Talpalar, A.E.2
Ben-Yaakov, K.3
Schwartz, M.4
-
57
-
-
0141991166
-
Complement activation and regulation in Alzheimer's disease
-
Shen, Y.; Meri, S. Complement activation and regulation in Alzheimer's disease. Prog. Neurobiol., 2003, 70, 463-472.
-
(2003)
Prog. Neurobiol
, vol.70
, pp. 463-472
-
-
Shen, Y.1
Meri, S.2
-
58
-
-
0030817147
-
Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease
-
Webster, S.; Lue, L.F.; Brachova, L.; Tenner, A.J.; McGeer, P.L.; Terai, K.; Walker, D.G.; Bradt, B.; Cooper, N.R.; Rogers, J. Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease. Neurobiol. Aging, 1997, 18, 415-21.
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 415-421
-
-
Webster, S.1
Lue, L.F.2
Brachova, L.3
Tenner, A.J.4
McGeer, P.L.5
Terai, K.6
Walker, D.G.7
Bradt, B.8
Cooper, N.R.9
Rogers, J.10
-
59
-
-
0037791771
-
Activation of complement in the central nervous system
-
van Beek, J.; Elward, K.; Gasque, P. Activation of complement in the central nervous system. Ann. N.Y. Acad. Sci., 2003, 992, 56-71.
-
(2003)
Ann. N.Y. Acad. Sci
, vol.992
, pp. 56-71
-
-
van Beek, J.1
Elward, K.2
Gasque, P.3
-
60
-
-
0036841667
-
The possible role of complement activation in Alzheimer disease
-
McGeer, P.L.; McGeer, E.G. The possible role of complement activation in Alzheimer disease. Trends Mol. Med., 2002, 8, 519-523.
-
(2002)
Trends Mol. Med
, vol.8
, pp. 519-523
-
-
McGeer, P.L.1
McGeer, E.G.2
-
61
-
-
0030175273
-
Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions
-
Pasinetti, G.M.; Tocco, G.; Sakhi, S.; Musleh, W.D.; DeSimoni, M.G.; Mascarucci, P.; Schreiber, S.; Baudry, M.; Finch, C.E. Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions. Neurobiol. Dis., 1996, 3, 197-204.
-
(1996)
Neurobiol. Dis
, vol.3
, pp. 197-204
-
-
Pasinetti, G.M.1
Tocco, G.2
Sakhi, S.3
Musleh, W.D.4
DeSimoni, M.G.5
Mascarucci, P.6
Schreiber, S.7
Baudry, M.8
Finch, C.E.9
-
62
-
-
0026447529
-
Complement activation by beta-amyloid in Alzheimer disease
-
Rogers, J.; Cooper, N.R.; Webster, S.; Schultz, J.; McGeer, P.L.; Styren, S.D.; Civin, W.H.; Brachova, L.; Bradt, B.; Ward, P.; Lieberburg, I. Complement activation by beta-amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. USA, 1992, 89, 10016-10020.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10016-10020
-
-
Rogers, J.1
Cooper, N.R.2
Webster, S.3
Schultz, J.4
McGeer, P.L.5
Styren, S.D.6
Civin, W.H.7
Brachova, L.8
Bradt, B.9
Ward, P.10
Lieberburg, I.11
-
63
-
-
0030250852
-
The role of complement and activated microglia in the pathogenesis of Alzheimer's disease
-
Eikelenboom, P.; Veerhuis, R. The role of complement and activated microglia in the pathogenesis of Alzheimer's disease. Neurobiol. Aging, 1996, 17, 673-680.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 673-680
-
-
Eikelenboom, P.1
Veerhuis, R.2
-
64
-
-
0027966134
-
-
Snyder, S.W.; Wang, G.T.; Barrett, L; Ladror, U.S.; Casuto, D.; Lee, C.M.; Krafft, G.A.; Holzman, R.B.; Holzman, T.F. Complement C1q does not bind monomeric beta-amyloid. Exp. Neurol., 1994, 128, 136-142.
-
Snyder, S.W.; Wang, G.T.; Barrett, L; Ladror, U.S.; Casuto, D.; Lee, C.M.; Krafft, G.A.; Holzman, R.B.; Holzman, T.F. Complement C1q does not bind monomeric beta-amyloid. Exp. Neurol., 1994, 128, 136-142.
-
-
-
-
65
-
-
0033526660
-
Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs
-
Yasojima, K.; Schwab, C.; McGeer, E.G.; McGeer, P.L. Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs. Brain Res., 1999, 830, 226-236.
-
(1999)
Brain Res
, vol.830
, pp. 226-236
-
-
Yasojima, K.1
Schwab, C.2
McGeer, E.G.3
McGeer, P.L.4
-
66
-
-
0029053689
-
Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines
-
Gasque, P.; Fontaine, M.; Morgan, B.P. Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines. J. Immunol., 1995, 154, 4726-4733.
-
(1995)
J. Immunol
, vol.154
, pp. 4726-4733
-
-
Gasque, P.1
Fontaine, M.2
Morgan, B.P.3
-
67
-
-
3242766671
-
Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease
-
Fonseca, M.I.; Zhou, J.; Botto, M.; Tenner, A.J. Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. J. Neurosci., 2004, 24, 6457-6465.
-
(2004)
J. Neurosci
, vol.24
, pp. 6457-6465
-
-
Fonseca, M.I.1
Zhou, J.2
Botto, M.3
Tenner, A.J.4
-
68
-
-
32144454172
-
The many roles of chemokines and chemokine receptors in inflammation
-
Charo, I.F.; Ransohoff, R.M. The many roles of chemokines and chemokine receptors in inflammation. N. Engl. J. Med., 2006, 354, 610-621.
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 610-621
-
-
Charo, I.F.1
Ransohoff, R.M.2
-
69
-
-
0032917904
-
Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease
-
Xia, M.Q.; Hyman, B.T. Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease. J. Neurovirol., 1999, 5, 32-41.
-
(1999)
J. Neurovirol
, vol.5
, pp. 32-41
-
-
Xia, M.Q.1
Hyman, B.T.2
-
70
-
-
0036277146
-
Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes
-
Smits, H.A.; Rijsmus, A.; van Loon, J.H.; Wat, J.W.; Verhoef, J.; Boven, L.A;. Nottet, H.S. Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes. J. Neuroimmunol., 2002, 127, 160-168.
-
(2002)
J. Neuroimmunol
, vol.127
, pp. 160-168
-
-
Smits, H.A.1
Rijsmus, A.2
van Loon, J.H.3
Wat, J.W.4
Verhoef, J.5
Boven, L.A.6
Nottet, H.S.7
-
71
-
-
0034948192
-
Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro
-
Lue, L.F.; Rydel, R.; Brigham, E.F.; Yang, L.B.; Hampel, H.; Murphy, G.M.; Brachova, L.; Yan, S.D.; Walker, D.G.; Shen, Y.; Rogers, J. Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro. Glia, 2001, 35, 72-79.
-
(2001)
Glia
, vol.35
, pp. 72-79
-
-
Lue, L.F.1
Rydel, R.2
Brigham, E.F.3
Yang, L.B.4
Hampel, H.5
Murphy, G.M.6
Brachova, L.7
Yan, S.D.8
Walker, D.G.9
Shen, Y.10
Rogers, J.11
-
72
-
-
0030988629
-
Immunohistochemical examination of phosphorylated tau in granulovacolar degeneration granules
-
Ishizuka, K.; Kimura, T.; Igata-yi, R.; Katsuragi, S.; Takamatsu, J.; Miyakawa, T. Immunohistochemical examination of phosphorylated tau in granulovacolar degeneration granules. Psychiatry Clin. Neurosci., 1997, 51, 135-138.
-
(1997)
Psychiatry Clin. Neurosci
, vol.51
, pp. 135-138
-
-
Ishizuka, K.1
Kimura, T.2
Igata-yi, R.3
Katsuragi, S.4
Takamatsu, J.5
Miyakawa, T.6
-
73
-
-
0031848322
-
Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains
-
Xia, M.Q.; Qin, S.X.; Wu, L.J.; Mackay, C.R.; Hyman, B.T. Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains. Am. J. Pathol., 1998, 153, 31-37.
-
(1998)
Am. J. Pathol
, vol.153
, pp. 31-37
-
-
Xia, M.Q.1
Qin, S.X.2
Wu, L.J.3
Mackay, C.R.4
Hyman, B.T.5
-
74
-
-
4944258716
-
The role of inflammation in Alzheimer's disease
-
Tuppo, E.E.; Arias, H.R. The role of inflammation in Alzheimer's disease. Int. J. Biochem. Cell Biol., 2005, 37, 289-305.
-
(2005)
Int. J. Biochem. Cell Biol
, vol.37
, pp. 289-305
-
-
Tuppo, E.E.1
Arias, H.R.2
-
75
-
-
0033029151
-
TGF-beta(1), regulation of alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: MRNA stabilization
-
Amara, F.M.; Junaid, A.; Clough, R.R.; Liang, B.H. TGF-beta(1), regulation of alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: mRNA stabilization. Mol. Brain Res., 1999, 71, 42-49.
-
(1999)
Mol. Brain Res
, vol.71
, pp. 42-49
-
-
Amara, F.M.1
Junaid, A.2
Clough, R.R.3
Liang, B.H.4
-
76
-
-
0032964511
-
Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy and Alzheimer's Disease (AD) individuals
-
Lombardi, V.R.; García, M.; Rey, L.; Cacabelos, R. Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy and Alzheimer's Disease (AD) individuals. J. Neuroimmunol., 1999, 97, 163-171.
-
(1999)
J. Neuroimmunol
, vol.97
, pp. 163-171
-
-
Lombardi, V.R.1
García, M.2
Rey, L.3
Cacabelos, R.4
-
77
-
-
0034053173
-
Association of interleukin-1 gene polymorphisms with Alzheimer's disease
-
Nicoll, J.A.; Mrak, R.E.; Graham, D.I.; Stewart, J.; Wilcock, G.; MacGowan, S.; Esiri, M.M.; Murray, L.S.; Dewar, D.; Love, S.; Moss, T.; Griffin, W.S. Association of interleukin-1 gene polymorphisms with Alzheimer's disease. Ann. Neurol., 2000, 47, 365-368.
-
(2000)
Ann. Neurol
, vol.47
, pp. 365-368
-
-
Nicoll, J.A.1
Mrak, R.E.2
Graham, D.I.3
Stewart, J.4
Wilcock, G.5
MacGowan, S.6
Esiri, M.M.7
Murray, L.S.8
Dewar, D.9
Love, S.10
Moss, T.11
Griffin, W.S.12
-
78
-
-
0027354484
-
Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
-
Dickson, D.W.; Lee, S.C.; Mattiace, L.A.; Yen, S.H.; Brosnan, C. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia, 1993, 7, 75-83.
-
(1993)
Glia
, vol.7
, pp. 75-83
-
-
Dickson, D.W.1
Lee, S.C.2
Mattiace, L.A.3
Yen, S.H.4
Brosnan, C.5
-
79
-
-
0030583248
-
Synergistic induction of nitric oxide by beta-amyloid and cytokines in astrocytes
-
Rossi, F.; Bianchini, E. Synergistic induction of nitric oxide by beta-amyloid and cytokines in astrocytes. Biochem. Biophys. Res. Commun., 1996, 225, 474-478.
-
(1996)
Biochem. Biophys. Res. Commun
, vol.225
, pp. 474-478
-
-
Rossi, F.1
Bianchini, E.2
-
80
-
-
0026760984
-
Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1 beta and tumor necrosis factor-alpha
-
Aloisi, F.; Care, A.; Borsellino, G.; Gallo, P.; Rosa, S.; Bassani, A.; Cabibbo, A.; Testa, U.; Levi, G.; Peschle, C. Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1 beta and tumor necrosis factor-alpha. J. Immunol., 1992, 149, 2358-2366.
-
(1992)
J. Immunol
, vol.149
, pp. 2358-2366
-
-
Aloisi, F.1
Care, A.2
Borsellino, G.3
Gallo, P.4
Rosa, S.5
Bassani, A.6
Cabibbo, A.7
Testa, U.8
Levi, G.9
Peschle, C.10
-
81
-
-
0026722679
-
Interleukin 1 and tumor necrosis factor-alpha stimulate the production of colony-stimulating factor 1 by murine astrocytes
-
Thery, C.; Stanley, E.R.; Mallat, M. Interleukin 1 and tumor necrosis factor-alpha stimulate the production of colony-stimulating factor 1 by murine astrocytes. J. Neurochem., 1992, 59, 1183-1186.
-
(1992)
J. Neurochem
, vol.59
, pp. 1183-1186
-
-
Thery, C.1
Stanley, E.R.2
Mallat, M.3
-
82
-
-
0034233382
-
The pervasiveness of interleukin-1 in alzheimer pathogenesis: A role for specific polymorphisms in disease risk
-
Griffin, W.S.; Nicoll, J.A.; Grimaldi, L.M.; Sheng, J.G.; Mrak, R.E. The pervasiveness of interleukin-1 in alzheimer pathogenesis: a role for specific polymorphisms in disease risk. Exp. Gerontol., 2000, 35, 481-487.
-
(2000)
Exp. Gerontol
, vol.35
, pp. 481-487
-
-
Griffin, W.S.1
Nicoll, J.A.2
Grimaldi, L.M.3
Sheng, J.G.4
Mrak, R.E.5
-
83
-
-
0031983986
-
Glialneuronal interactions in Alzheimer's disease: The potential role of a 'cytokine cycle' in disease progression
-
Griffin, W.S.; Sheng, J.G.; Royston, M.C.; Gentleman, S.M.; McKenzie, J.E.; Graham, D.I.; Roberts, G.W.; Mrak, R.E. Glialneuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression. Brain Pathol., 1998, 8, 65-72.
-
(1998)
Brain Pathol
, vol.8
, pp. 65-72
-
-
Griffin, W.S.1
Sheng, J.G.2
Royston, M.C.3
Gentleman, S.M.4
McKenzie, J.E.5
Graham, D.I.6
Roberts, G.W.7
Mrak, R.E.8
-
84
-
-
0035690976
-
Interleukin-1, neuroinflammation, and Alzheimer's disease
-
Mrak, R.E.; Griffin, W.S. Interleukin-1, neuroinflammation, and Alzheimer's disease. Neurobiol. Aging, 2001, 22, 903-908.
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 903-908
-
-
Mrak, R.E.1
Griffin, W.S.2
-
85
-
-
0025092159
-
Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor
-
Selmaj, K.W.; Farooq, M.; Norton, W.T.; Raine, C.S.; Brosnan, C.F. Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor. J. Immunol., 1990, 144, 129-135.
-
(1990)
J. Immunol
, vol.144
, pp. 129-135
-
-
Selmaj, K.W.1
Farooq, M.2
Norton, W.T.3
Raine, C.S.4
Brosnan, C.F.5
-
86
-
-
0031028141
-
Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain
-
Heyser, C.J.; Masliah, E.; Samimi, A.; Campbell, I.L.; Gold, L.H. Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proc. Natl. Acad. Sci. USA, 1997, 940, 1500-1505.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, Issue.0
, pp. 1500-1505
-
-
Heyser, C.J.1
Masliah, E.2
Samimi, A.3
Campbell, I.L.4
Gold, L.H.5
-
87
-
-
0024323353
-
Interleukin-6: The major regulator of acute-phase protein synthesis in man and rat
-
Castell, J.V.; Andus, T.; Kunz, D.; Heinrich, P.C. Interleukin-6: The major regulator of acute-phase protein synthesis in man and rat. Ann. N. Y. Acad. Sci. USA, 1989, 557, 87-101.
-
(1989)
Ann. N. Y. Acad. Sci. USA
, vol.557
, pp. 87-101
-
-
Castell, J.V.1
Andus, T.2
Kunz, D.3
Heinrich, P.C.4
-
88
-
-
0034523456
-
Costimulatory effects of interferon-gamma and interleukin-1beta or tumor necrosis factor alpha on the synthesis of Abeta1-40 and Abeta1-42 by human astrocytes
-
Blasko, I.; Veerhuis, R.; Stampfer-Kountchev, M.; Saurwein-Teissl, M.; Eikelenboom, P.; Grubeck-Loebenstein, B. Costimulatory effects of interferon-gamma and interleukin-1beta or tumor necrosis factor alpha on the synthesis of Abeta1-40 and Abeta1-42 by human astrocytes. Neurobiol. Dis., 2000, 7, 682-689.
-
(2000)
Neurobiol. Dis
, vol.7
, pp. 682-689
-
-
Blasko, I.1
Veerhuis, R.2
Stampfer-Kountchev, M.3
Saurwein-Teissl, M.4
Eikelenboom, P.5
Grubeck-Loebenstein, B.6
-
89
-
-
0029033167
-
Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: Evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation
-
Barger, S.W.; Horster, D.; Furukawa, K.; Goodman, Y.; Krieglstein, J.; Mattson, M.P. Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation. Proc. Natl. Acad. Sci. USA, 1995, 92, 9328-9332.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9328-9332
-
-
Barger, S.W.1
Horster, D.2
Furukawa, K.3
Goodman, Y.4
Krieglstein, J.5
Mattson, M.P.6
-
90
-
-
0035866060
-
-
Combs, C.K.; Karlo, J.C.; Kao, S.C.; Landreth, G.E. beta-Amyloid stimulation of microglia and monocytes results in TNFalphadependent expression of inducible nitric oxide synthase and neuronal apoptosis. J. Neurosci., 2001, 21, 1179-1188.
-
Combs, C.K.; Karlo, J.C.; Kao, S.C.; Landreth, G.E. beta-Amyloid stimulation of microglia and monocytes results in TNFalphadependent expression of inducible nitric oxide synthase and neuronal apoptosis. J. Neurosci., 2001, 21, 1179-1188.
-
-
-
-
91
-
-
0034612175
-
-
Akiyama, H.; Barger, S.; Barnum, S.; Bradt, B.; Bauer, J.; Cole, G.M.; Cooper, N.R.; Eikelenboom, P.; Emmerling, M.; Fiebich, B.L.; Finch, C.E.; Frautschy, S.; Griffin, W.S.; Hampel, H.; Hull, M.; Landreth, G.; Lue, L.; Mrak, R.; Mackenzie, I.R.; McGeer, P.L.; O'Banion, M.K.; Pachter, J.; Pasinetti, G.; Plata-Salaman, C.; Rogers, J.; Rydel, R.; Shen, Y.; Streit, W.; Strohmeyer, R.; Tooyoma, I.; Van Muiswinkel, F.L.; Veerhuis, R.; Walker, D.; Webster, S.; Wegrzyniak, B.; Wenk, G.; Wyss-Coray, T. Inflammation and Alzheimer's disease. Neurobiol. Aging, 2000, 21, 383-421.
-
Akiyama, H.; Barger, S.; Barnum, S.; Bradt, B.; Bauer, J.; Cole, G.M.; Cooper, N.R.; Eikelenboom, P.; Emmerling, M.; Fiebich, B.L.; Finch, C.E.; Frautschy, S.; Griffin, W.S.; Hampel, H.; Hull, M.; Landreth, G.; Lue, L.; Mrak, R.; Mackenzie, I.R.; McGeer, P.L.; O'Banion, M.K.; Pachter, J.; Pasinetti, G.; Plata-Salaman, C.; Rogers, J.; Rydel, R.; Shen, Y.; Streit, W.; Strohmeyer, R.; Tooyoma, I.; Van Muiswinkel, F.L.; Veerhuis, R.; Walker, D.; Webster, S.; Wegrzyniak, B.; Wenk, G.; Wyss-Coray, T. Inflammation and Alzheimer's disease. Neurobiol. Aging, 2000, 21, 383-421.
-
-
-
-
92
-
-
0032621790
-
TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs
-
Blasko, I.; Marx, F.; Steiner, E.; Hartmann, T.; Grubeck- Loebenstein, B. TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs. FASEB J., 1999, 13, 63-8.
-
(1999)
FASEB J
, vol.13
, pp. 63-68
-
-
Blasko, I.1
Marx, F.2
Steiner, E.3
Hartmann, T.4
Grubeck- Loebenstein, B.5
-
93
-
-
0028099622
-
Inflammatory mechanisms in Alzheimer's disease
-
Eikelenboom, P.; Zhan, S.S.; vanGool, W.A.; Allsop, D. Inflammatory mechanisms in Alzheimer's disease. Trends Pharmacol. Sci., 1994, 15, 447-450.
-
(1994)
Trends Pharmacol. Sci
, vol.15
, pp. 447-450
-
-
Eikelenboom, P.1
Zhan, S.S.2
vanGool, W.A.3
Allsop, D.4
-
94
-
-
1542283611
-
Neuroinflammatory perspectives on the two faces of Alzheimer's disease
-
Eikelenboom, P.; van Gool,W.A. Neuroinflammatory perspectives on the two faces of Alzheimer's disease. J. Neural Transm., 2004, 111, 281-294.
-
(2004)
J. Neural Transm
, vol.111
, pp. 281-294
-
-
Eikelenboom, P.1
van Gool, W.A.2
-
95
-
-
0034932973
-
C-terminal fragment of amyloid precursor protein induces astrocytosis
-
Bach, J.H.; Chae, H.S.; Rah, J.C.; Lee, M.W.; Park, C.H.; Choi, S.H.; Choi, J.K.; Lee, S.H.; Kim, Y.S.; Kim, K.Y.; Lee, W.B.; Suh, Y.H.; Kim, S.S. C-terminal fragment of amyloid precursor protein induces astrocytosis. J. Neurochem., 2001, 78, 109-120.
-
(2001)
J. Neurochem
, vol.78
, pp. 109-120
-
-
Bach, J.H.1
Chae, H.S.2
Rah, J.C.3
Lee, M.W.4
Park, C.H.5
Choi, S.H.6
Choi, J.K.7
Lee, S.H.8
Kim, Y.S.9
Kim, K.Y.10
Lee, W.B.11
Suh, Y.H.12
Kim, S.S.13
-
96
-
-
33646841989
-
Beta-amyloid stimulates murine postnatal and adult microglia cultures in a unique manner
-
Floden, A.M.; Combs, C.K. Beta-amyloid stimulates murine postnatal and adult microglia cultures in a unique manner. J. Neurosci. 2006, 26, 4644-4648.
-
(2006)
J. Neurosci
, vol.26
, pp. 4644-4648
-
-
Floden, A.M.1
Combs, C.K.2
-
97
-
-
23444455475
-
β-amyloid protein structure determines the nature of cytokine release from rat microglia
-
Lindberg, C.; Selenica, M.L.B.; Westlind-Danielsson, A.; Schultzberg, M. β-amyloid protein structure determines the nature of cytokine release from rat microglia. J. Mol. Neurosci., 2005, 27, 1-12.
-
(2005)
J. Mol. Neurosci
, vol.27
, pp. 1-12
-
-
Lindberg, C.1
Selenica, M.L.B.2
Westlind-Danielsson, A.3
Schultzberg, M.4
-
98
-
-
0034802570
-
Immunological aspects of microglia: Relevance to Alzheimer's disease
-
Benveniste, E.N.; Nguyen, V.T.; O'Keefe, G.M. Immunological aspects of microglia: relevance to Alzheimer's disease. Neurochem. Int., 2001, 39, 381-391.
-
(2001)
Neurochem. Int
, vol.39
, pp. 381-391
-
-
Benveniste, E.N.1
Nguyen, V.T.2
O'Keefe, G.M.3
-
99
-
-
0036849018
-
Microglia as a source and target of cytokines
-
Hanisch, U.K. Microglia as a source and target of cytokines. Glia, 2002, 40, 140-155.
-
(2002)
Glia
, vol.40
, pp. 140-155
-
-
Hanisch, U.K.1
-
100
-
-
0036644961
-
Cytokines, chemokines, and cytokine receptors in human microglia
-
Lee, Y.B.; Nagai, A.; Kim, S.U. Cytokines, chemokines, and cytokine receptors in human microglia. J. Neurosci. Res., 2002, 69, 94-103.
-
(2002)
J. Neurosci. Res
, vol.69
, pp. 94-103
-
-
Lee, Y.B.1
Nagai, A.2
Kim, S.U.3
-
101
-
-
0025763298
-
2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices
-
2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices. FEBS Lett., 1991, 285, 111-114.
-
(1991)
FEBS Lett
, vol.285
, pp. 111-114
-
-
Bauer, J.1
Strauss, S.2
Schreiter-Gasser, U.3
Ganter, U.4
Sclegel, P.5
Witt, I.6
Yolk, B.7
Berger, M.8
-
102
-
-
21044448540
-
Mechanisms of cell signaling and inflammation in Alzheimer's disease
-
Ho, G.J.; Drego, R.; Hakimian, E.; Masliah, E. Mechanisms of cell signaling and inflammation in Alzheimer's disease. Curr. Drug Targets Inflamm. Allergy, 2005, 4, 247-256.
-
(2005)
Curr. Drug Targets Inflamm. Allergy
, vol.4
, pp. 247-256
-
-
Ho, G.J.1
Drego, R.2
Hakimian, E.3
Masliah, E.4
-
103
-
-
0028675999
-
Cytokines, inflammation, and brain injury: Role of tumor necrosis factor-alpha
-
Feuerstein, G.Z.; Liu, T.; Barone, F.C. Cytokines, inflammation, and brain injury: role of tumor necrosis factor-alpha. Cerebrovasc. Brain Metab. Rev., 1994, 6, 341-360.
-
(1994)
Cerebrovasc. Brain Metab. Rev
, vol.6
, pp. 341-360
-
-
Feuerstein, G.Z.1
Liu, T.2
Barone, F.C.3
-
104
-
-
0035690770
-
Inflammatory factors are elevated in brain microvessels in Alzheimer's disease
-
Grammas, P.; Ovase, R. Inflammatory factors are elevated in brain microvessels in Alzheimer's disease. Neurobiol. Aging, 2001, 22, 837-842.
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 837-842
-
-
Grammas, P.1
Ovase, R.2
-
105
-
-
33745252827
-
Increased intrathecal TGF-beta1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimer's disease patients
-
Rota, E.; Bellone, G.; Rocca, P.; Bergamasco, B.; Emanuelli, G.; Ferrero, P. Increased intrathecal TGF-beta1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimer's disease patients. Neurol. Sci., 2006, 27, 33-39.
-
(2006)
Neurol. Sci
, vol.27
, pp. 33-39
-
-
Rota, E.1
Bellone, G.2
Rocca, P.3
Bergamasco, B.4
Emanuelli, G.5
Ferrero, P.6
-
106
-
-
0035255055
-
IL-4, IL- 10 and IL-13 modulate A beta(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line
-
Szczepanik, A.M.; Funes, S.; Petko,W.; Ringheim, G.E. IL-4, IL- 10 and IL-13 modulate A beta(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line. J. Neuroimmunol., 2001, 113, 49-62.
-
(2001)
J. Neuroimmunol
, vol.113
, pp. 49-62
-
-
Szczepanik, A.M.1
Funes, S.2
Petko, W.3
Ringheim, G.E.4
-
107
-
-
0035085610
-
Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo
-
Szczepanik, A.M.; Rampe, D.; Ringheim, G.E. Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo. J. Neurochem., 2001, 77, 304-317.
-
(2001)
J. Neurochem
, vol.77
, pp. 304-317
-
-
Szczepanik, A.M.1
Rampe, D.2
Ringheim, G.E.3
-
108
-
-
14844322281
-
Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin- 1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients
-
Reale, M.; Iarlori, C.; Gambi, F.; Lucci, I.; Salvatore, M.; Gambi, D. Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin- 1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients. Exp. Gerontol., 2005, 40, 165-171.
-
(2005)
Exp. Gerontol
, vol.40
, pp. 165-171
-
-
Reale, M.1
Iarlori, C.2
Gambi, F.3
Lucci, I.4
Salvatore, M.5
Gambi, D.6
-
109
-
-
0032896588
-
Cyclooxygenase-2: Molecular biology, pharmacology, and neurobiology
-
O'Banion, M.K. Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology. Crit. Rev. Neurobiol., 1999, 13, 45-82.
-
(1999)
Crit. Rev. Neurobiol
, vol.13
, pp. 45-82
-
-
O'Banion, M.K.1
-
110
-
-
0031689543
-
Cyclooxygenase in biology and disease
-
Dubois, R.N.; Abramson, S.B.; Crofford, L.; Gupta, R.A.; Simon, L.S.; Van De Putte, L.B.A.; Lipsky, P.E. Cyclooxygenase in biology and disease. FASEB J., 1998, 12, 1063-73.
-
(1998)
FASEB J
, vol.12
, pp. 1063-1073
-
-
Dubois, R.N.1
Abramson, S.B.2
Crofford, L.3
Gupta, R.A.4
Simon, L.S.5
Van De Putte, L.B.A.6
Lipsky, P.E.7
-
111
-
-
0031015384
-
Expression and regulation of cyclooxygenase-2 in rat microglia
-
Bauer, M.K.; Lieb, K.; Schulze-Osthoff, K.; Berger, M.; Gebicke- Haerter, P.J.; Bauer, J.; Fiebich, B.L. Expression and regulation of cyclooxygenase-2 in rat microglia. Eur. J. Biochem., 1997, 243, 726-731.
-
(1997)
Eur. J. Biochem
, vol.243
, pp. 726-731
-
-
Bauer, M.K.1
Lieb, K.2
Schulze-Osthoff, K.3
Berger, M.4
Gebicke- Haerter, P.J.5
Bauer, J.6
Fiebich, B.L.7
-
112
-
-
0035141118
-
Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain
-
Hoozemans, J.J.M.; Rozemuller, A.J.M.; Janssen, I.; De Groot, C.J.A.; Veerhuis, R.; Eikelenboom, P. Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain. Acta Neuropathol., 2001, 101, 2-8.
-
(2001)
Acta Neuropathol
, vol.101
, pp. 2-8
-
-
Hoozemans, J.J.M.1
Rozemuller, A.J.M.2
Janssen, I.3
De Groot, C.J.A.4
Veerhuis, R.5
Eikelenboom, P.6
-
113
-
-
0033694033
-
Cyclooxygenases in the central nervous system: Implications for treatment of neurological disorders
-
Yermakova, A.; O'Banion, M.K. Cyclooxygenases in the central nervous system: implications for treatment of neurological disorders. Curr. Pharm. Des., 2000, 6, 1755-1776.
-
(2000)
Curr. Pharm. Des
, vol.6
, pp. 1755-1776
-
-
Yermakova, A.1
O'Banion, M.K.2
-
114
-
-
0030994412
-
Upregulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs
-
Minghetti, L.; Polazzi, E.; Nicolini, A.; Creminon, C.; Levi, G. Upregulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs. Eur. J. Neurosci. 1997, 9, 934-940.
-
(1997)
Eur. J. Neurosci
, vol.9
, pp. 934-940
-
-
Minghetti, L.1
Polazzi, E.2
Nicolini, A.3
Creminon, C.4
Levi, G.5
-
115
-
-
0032740467
-
Elevated CSF prostaglandin E2 levels in patients with probable AD
-
Montine, T.J.; Sidell, K.R.; Crews, B.C.; Markesbery, W.R.; Marnett, L.J.; Roberts, L.J.; Morrow, J.D. Elevated CSF prostaglandin E2 levels in patients with probable AD. Neurology, 1999, 53, 1495-1498.
-
(1999)
Neurology
, vol.53
, pp. 1495-1498
-
-
Montine, T.J.1
Sidell, K.R.2
Crews, B.C.3
Markesbery, W.R.4
Marnett, L.J.5
Roberts, L.J.6
Morrow, J.D.7
-
116
-
-
34249729416
-
Prostaglandin E receptors
-
Sugimoto, Y; Narumiya, S. Prostaglandin E receptors. J. Biol. Chem., 2007, 282, 11613-11617.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 11613-11617
-
-
Sugimoto, Y.1
Narumiya, S.2
-
117
-
-
4444274138
-
Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum
-
Slawik, H.; Volk, B.; Fiebich, B.; Hull, M. Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum. Neurochem. Int., 2004, 45, 653-660.
-
(2004)
Neurochem. Int
, vol.45
, pp. 653-660
-
-
Slawik, H.1
Volk, B.2
Fiebich, B.3
Hull, M.4
-
118
-
-
17144380506
-
Microglia lacking E Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity
-
Shie, F.S.; Breyer, R.M.; Montine, T.J. Microglia lacking E Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity. Am. J. Pathol., 2005, 166, 1163-1172.
-
(2005)
Am. J. Pathol
, vol.166
, pp. 1163-1172
-
-
Shie, F.S.1
Breyer, R.M.2
Montine, T.J.3
-
119
-
-
0035205575
-
Mechanisms of prostaglandin E2-induced interleukin-6 release in astrocytes: Possible involvement of EP4-like receptors, p38 mitogen- activated protein kinase and protein kinase C
-
Fiebich, B.L.; Schleicher, S.; Spleiss, O.; Czygan, M.; Hull, M. Mechanisms of prostaglandin E2-induced interleukin-6 release in astrocytes: possible involvement of EP4-like receptors, p38 mitogen- activated protein kinase and protein kinase C. J. Neurochem., 2001, 79, 950-958.
-
(2001)
J. Neurochem
, vol.79
, pp. 950-958
-
-
Fiebich, B.L.1
Schleicher, S.2
Spleiss, O.3
Czygan, M.4
Hull, M.5
-
120
-
-
3843129633
-
PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis
-
Bilak, M.; Wu, L.; Wang, Q.; Haughey, N.; Conant, K.; St Hillaire, C.; Andreasson, K. PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis. Ann. Neurol., 2004, 56, 240-248.
-
(2004)
Ann. Neurol
, vol.56
, pp. 240-248
-
-
Bilak, M.1
Wu, L.2
Wang, Q.3
Haughey, N.4
Conant, K.5
St Hillaire, C.6
Andreasson, K.7
-
121
-
-
46149084859
-
Prostaglandin receptor EP2 protects dopaminergic neurons against 6-OHDA-mediated low oxidative stress
-
Carrasco, E.; Werner, P.; Casper, D. Prostaglandin receptor EP2 protects dopaminergic neurons against 6-OHDA-mediated low oxidative stress. Neurosci. Lett., 2008, 441, 44-49.
-
(2008)
Neurosci. Lett
, vol.441
, pp. 44-49
-
-
Carrasco, E.1
Werner, P.2
Casper, D.3
-
122
-
-
0035100231
-
Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease
-
Ho, L.; Purohit, D.; Haroutunian, V.; Luterman, J.D.; Willis, F.; Naslund, J.; Buxbaum, J.D.; Mohs, R.C.; Aisen, P.S.; Pasinetti, G.M. Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease. Arch. Neurol., 2001, 58, 487-492.
-
(2001)
Arch. Neurol
, vol.58
, pp. 487-492
-
-
Ho, L.1
Purohit, D.2
Haroutunian, V.3
Luterman, J.D.4
Willis, F.5
Naslund, J.6
Buxbaum, J.D.7
Mohs, R.C.8
Aisen, P.S.9
Pasinetti, G.M.10
-
123
-
-
0033608169
-
Identification of the region of mi transcription factor which is responsible for the synergy with PEBP2/CBF
-
Kitamura, Y.; Shimohama, S.; Koike, H.; Kakimura, J.; Matsuoka, Y.; Nomura, Y.; Gebicke-Haerter, P.J.; Taniguchi, T. Identification of the region of mi transcription factor which is responsible for the synergy with PEBP2/CBF. Biochem. Biophys. Res. Commun., 1999, 254, 582-589.
-
(1999)
Biochem. Biophys. Res. Commun
, vol.254
, pp. 582-589
-
-
Kitamura, Y.1
Shimohama, S.2
Koike, H.3
Kakimura, J.4
Matsuoka, Y.5
Nomura, Y.6
Gebicke-Haerter, P.J.7
Taniguchi, T.8
-
124
-
-
0030951257
-
Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: Specific localization in affected neurones and axons
-
Oka, A.; Takashima, S. Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: specific localization in affected neurones and axons. Neuroreport, 1997, 8, 1161-1164.
-
(1997)
Neuroreport
, vol.8
, pp. 1161-1164
-
-
Oka, A.1
Takashima, S.2
-
125
-
-
0035693794
-
Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer's disease
-
Yermakova, A.V.; O'Banion, M.K. Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer's disease. Neurobiol. Aging, 2001, 22, 823-836.
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 823-836
-
-
Yermakova, A.V.1
O'Banion, M.K.2
-
126
-
-
0031453714
-
Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex
-
Lukiw, W.J.; Bazan, N.G. Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex. J. Neurosci. Res., 1997, 50, 937-945.
-
(1997)
J. Neurosci. Res
, vol.50
, pp. 937-945
-
-
Lukiw, W.J.1
Bazan, N.G.2
-
127
-
-
0041302369
-
Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia
-
Candelario-Jalil, E.; Gonzalez-Falcon, A.; Garcia-Cabrera, M.; Alvarez, D.; Al Dalain, S.; Martinez, G.; Leon, O.S.; Springer, J.E. Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia. J. Neurochem., 2003, 86, 545-55.
-
(2003)
J. Neurochem
, vol.86
, pp. 545-555
-
-
Candelario-Jalil, E.1
Gonzalez-Falcon, A.2
Garcia-Cabrera, M.3
Alvarez, D.4
Al Dalain, S.5
Martinez, G.6
Leon, O.S.7
Springer, J.E.8
-
128
-
-
17844378699
-
Regulation of prostaglandin E2 synthesis after brain irradiation
-
Moore, A.H.; Olschowka, J.A.; Williams, J.P.; Okunieff, P.; O'Banion, M.K. Regulation of prostaglandin E2 synthesis after brain irradiation. Int. J. Radiat. Oncol. Biol. Phys., 2005, 62, 267-272.
-
(2005)
Int. J. Radiat. Oncol. Biol. Phys
, vol.62
, pp. 267-272
-
-
Moore, A.H.1
Olschowka, J.A.2
Williams, J.P.3
Okunieff, P.4
O'Banion, M.K.5
-
129
-
-
0032725481
-
Cyclooxygenase-1 in human Alzheimer and control brain: Quantitative analysis of expression by microglia and CA3 hippocampal neurons
-
Yermakova, A.V.; Rollins, J.; Callahan, L.M.; Rogers, J.; O'Banion, M.K. Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons. J. Neuropathol. Exp. Neurol., 1999, 58, 1135-1146.
-
(1999)
J. Neuropathol. Exp. Neurol
, vol.58
, pp. 1135-1146
-
-
Yermakova, A.V.1
Rollins, J.2
Callahan, L.M.3
Rogers, J.4
O'Banion, M.K.5
-
130
-
-
10444280038
-
Structure-function studies on nitric oxide synthases
-
Li, H.; Poulos, T.L. Structure-function studies on nitric oxide synthases. J. Inorg. Biochem., 2005, 99, 293-305.
-
(2005)
J. Inorg. Biochem
, vol.99
, pp. 293-305
-
-
Li, H.1
Poulos, T.L.2
-
131
-
-
0026486613
-
Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures
-
Galea, E.; Feinstein, D.L.; Reis, D.J. Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures. Proc. Natl. Acad. Sci. USA, 1992, 89, 10945-49.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10945-10949
-
-
Galea, E.1
Feinstein, D.L.2
Reis, D.J.3
-
132
-
-
0031949810
-
Inducible nitric oxide synthase in human diseases
-
Kroncke, K.D.; Fehsel, K.; Kolb-Bachofen, V. Inducible nitric oxide synthase in human diseases. Clin. Exp. Immunol., 1998, 113, 147-156.
-
(1998)
Clin. Exp. Immunol
, vol.113
, pp. 147-156
-
-
Kroncke, K.D.1
Fehsel, K.2
Kolb-Bachofen, V.3
-
133
-
-
0034769118
-
Nitric oxide and the immune response
-
Bogdan, C. Nitric oxide and the immune response. Nat. Immunol., 2001, 2, 907-916.
-
(2001)
Nat. Immunol
, vol.2
, pp. 907-916
-
-
Bogdan, C.1
-
134
-
-
0027563713
-
Inducible nitric oxide synthase activity of cloned murine microglial cells
-
Corradin, S.B.; Mauel, J.; Donini, S.D.; Quattrocchi, E.; Ricciardi- Castagnoli, P. Inducible nitric oxide synthase activity of cloned murine microglial cells. Glia, 1993, 7, 255-62.
-
(1993)
Glia
, vol.7
, pp. 255-262
-
-
Corradin, S.B.1
Mauel, J.2
Donini, S.D.3
Quattrocchi, E.4
Ricciardi- Castagnoli, P.5
-
135
-
-
2642605346
-
Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide
-
Heneka, M.T.; Loschmann, P.A.; Gleichmann, M.; Weller, M.; Schulz, J.B.; Wullner, U.; Klockgether, T. Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide. J. Neurochem., 1998, 71, 88-94.
-
(1998)
J. Neurochem
, vol.71
, pp. 88-94
-
-
Heneka, M.T.1
Loschmann, P.A.2
Gleichmann, M.3
Weller, M.4
Schulz, J.B.5
Wullner, U.6
Klockgether, T.7
-
136
-
-
0026774797
-
Induction of nitric oxide synthase in glial cells
-
Simmons, M.L.; Murphy, S. Induction of nitric oxide synthase in glial cells. J. Neurochem., 1992, 59, 897-905.
-
(1992)
J. Neurochem
, vol.59
, pp. 897-905
-
-
Simmons, M.L.1
Murphy, S.2
-
137
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura, A.; Perry, G.; Aliev, G.; Hirai, K.; Takeda, A.; Balraj, E.K.; Jones, P.K.; Ghanbari, H.; Wataya, T.; Shimohama, S.; Chiba, S.; Atwood, C.S.; Petersen, R.B.; Smith, M.A. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol., 2001, 60, 759-767.
-
(2001)
J. Neuropathol. Exp. Neurol
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
138
-
-
0031127418
-
Nitric oxide synthase in reactive astrocytes adjacent to beta-amyloid plaques
-
Wallace, M.N.; Geddes, J.G.; Farquhar, D.A.; Masson, M.R. Nitric oxide synthase in reactive astrocytes adjacent to beta-amyloid plaques. Exp. Neurol., 1997, 144, 266-272.
-
(1997)
Exp. Neurol
, vol.144
, pp. 266-272
-
-
Wallace, M.N.1
Geddes, J.G.2
Farquhar, D.A.3
Masson, M.R.4
-
139
-
-
0026702955
-
Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
-
Boje, K.M.; Arora, P.K. Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res., 1992, 587, 250-256.
-
(1992)
Brain Res
, vol.587
, pp. 250-256
-
-
Boje, K.M.1
Arora, P.K.2
-
140
-
-
1842531469
-
Reaction of organic peroxyl radicals with •NO:2 and •NO in aqueous solution: Intermediacy of organic peroxynitrate and peroxynitrite species
-
Goldstein, S.; Lind, J.; Merényi, G. Reaction of organic peroxyl radicals with •NO:2 and •NO in aqueous solution: Intermediacy of organic peroxynitrate and peroxynitrite species. J. Phys. Chem. A., 2004, 108, 1719-1725.
-
(2004)
J. Phys. Chem. A
, vol.108
, pp. 1719-1725
-
-
Goldstein, S.1
Lind, J.2
Merényi, G.3
-
141
-
-
0025883342
-
Nitric oxide: Physiology, pathophysiology, and pharmacology
-
Moncada, S.R.; Palmer, M.J.; Higgs, E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev., 1991, 43, 109-142.
-
(1991)
Pharmacol. Rev
, vol.43
, pp. 109-142
-
-
Moncada, S.R.1
Palmer, M.J.2
Higgs, E.A.3
-
142
-
-
0026663451
-
Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions
-
Moncada, C.; Lekieffre, D.; Arvin, B.; Meldrum, B. Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions. Neuroreport., 1992, 3, 530-532.
-
(1992)
Neuroreport
, vol.3
, pp. 530-532
-
-
Moncada, C.1
Lekieffre, D.2
Arvin, B.3
Meldrum, B.4
-
143
-
-
0030108525
-
Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism
-
Chao, C.C.; Hu, S.; Sheng, W.S.; Bu, D.; Bukrinsky, M.I.; Peterson, P.K. Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia, 1996, 16, 276-284.
-
(1996)
Glia
, vol.16
, pp. 276-284
-
-
Chao, C.C.1
Hu, S.2
Sheng, W.S.3
Bu, D.4
Bukrinsky, M.I.5
Peterson, P.K.6
-
144
-
-
0028089896
-
Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures
-
Dawson, V.L.; Brahmbhatt, H.P.; Mong, J.A.; Dawson, T.M. Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures. Neuropharmacology, 1994, 33, 1425-1430.
-
(1994)
Neuropharmacology
, vol.33
, pp. 1425-1430
-
-
Dawson, V.L.1
Brahmbhatt, H.P.2
Mong, J.A.3
Dawson, T.M.4
-
145
-
-
0027221653
-
Nitric oxide synthase induction in glial cells: Effect on neuronal survival
-
Demerle-Pallardy, C.; Lonchampt, M.O.; Chabrier, P.E.; Braquet, P. Nitric oxide synthase induction in glial cells: effect on neuronal survival. Life Sci., 1993, 52, 1883-1890.
-
(1993)
Life Sci
, vol.52
, pp. 1883-1890
-
-
Demerle-Pallardy, C.1
Lonchampt, M.O.2
Chabrier, P.E.3
Braquet, P.4
-
146
-
-
34347383021
-
Nitric oxide and nitroxidative stress in Alzheimer's disease
-
Malinski, T. Nitric oxide and nitroxidative stress in Alzheimer's disease. J. Alzheimers Dis., 2007, 11, 207-218.
-
(2007)
J. Alzheimers Dis
, vol.11
, pp. 207-218
-
-
Malinski, T.1
-
147
-
-
34547673497
-
Peroxynitrite: Biochemistry,. pathophysiology and development of therapeutics
-
Szabó, C.; Ischiropoulos, H.; Radi, R. Peroxynitrite: biochemistry,. pathophysiology and development of therapeutics. Nat. Rev. Drug Discov., 2007, 6, 662-680.
-
(2007)
Nat. Rev. Drug Discov
, vol.6
, pp. 662-680
-
-
Szabó, C.1
Ischiropoulos, H.2
Radi, R.3
-
148
-
-
36749005178
-
Mechanisms of inflammatory neurodegeneration: INOS and NADPH oxidase
-
Brown, G.C. Mechanisms of inflammatory neurodegeneration: iNOS and NADPH oxidase. Biochem. Soc. Trans., 2007, 35, 1119-1121.
-
(2007)
Biochem. Soc. Trans
, vol.35
, pp. 1119-1121
-
-
Brown, G.C.1
-
149
-
-
0041784698
-
Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria
-
Brown, G.C.; Bal-Price, A. Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria. Mol. Neurobiol., 2003, 27, 325-355.
-
(2003)
Mol. Neurobiol
, vol.27
, pp. 325-355
-
-
Brown, G.C.1
Bal-Price, A.2
-
150
-
-
10244235267
-
Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease
-
Vodovotz, Y.; Lucia, M.S.; Flanders, K.C.; Chesler, L.; Xie, Q.W.; Smith, T.W.; Weidner, J.; Mumford, R.; Webber, R.; Nathan, C.; Roberts, A.B.; Lippa, C.F.; Sporn, M.B. Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease. J. Exp. Med., 1996, 184, 1425-1433.
-
(1996)
J. Exp. Med
, vol.184
, pp. 1425-1433
-
-
Vodovotz, Y.1
Lucia, M.S.2
Flanders, K.C.3
Chesler, L.4
Xie, Q.W.5
Smith, T.W.6
Weidner, J.7
Mumford, R.8
Webber, R.9
Nathan, C.10
Roberts, A.B.11
Lippa, C.F.12
Sporn, M.B.13
-
151
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in Alzheimer's disease
-
Smith, M.A.; Richey Harris, P.L.; Sayre, L.M.; Beckman, J.S.; Perry, G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J. Neurosci., 1997, 17, 2653-2657.
-
(1997)
J. Neurosci
, vol.17
, pp. 2653-2657
-
-
Smith, M.A.1
Richey Harris, P.L.2
Sayre, L.M.3
Beckman, J.S.4
Perry, G.5
-
152
-
-
0034612148
-
Inflammatory hypotheses: Novel mechanisms of Alzheimer's neurodegeneration and new therapeutic targets?
-
Praticò, D.; Trojanowski, J.Q. Inflammatory hypotheses: novel mechanisms of Alzheimer's neurodegeneration and new therapeutic targets? Neurobiol. Aging, 2000, 21, 441-445.
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 441-445
-
-
Praticò, D.1
Trojanowski, J.Q.2
-
153
-
-
0034084599
-
Neuroinflammation and Alzheimer disease: Clinical and therapeutic implications
-
Eikelenboom, P.; Rozemuller, A.J.; Hoozemans, J.J.; Veerhuis, R.; van Gool, W.A. Neuroinflammation and Alzheimer disease: clinical and therapeutic implications. Alzheimer Dis. Assoc. Disord., 2000, 14, S854-61.
-
(2000)
Alzheimer Dis. Assoc. Disord
, vol.14
-
-
Eikelenboom, P.1
Rozemuller, A.J.2
Hoozemans, J.J.3
Veerhuis, R.4
van Gool, W.A.5
-
154
-
-
0034811403
-
Inflammatory markers in Alzheimer's disease and multi-infarct dementia
-
De Luigi, A.; Fragiacomo, C.; Lucca, U.; Quadri, P.; Tettamanti, M.; De Simoni, M.G. Inflammatory markers in Alzheimer's disease and multi-infarct dementia. Mech. Aging Devel., 2001, 122, 1985-1995.
-
(2001)
Mech. Aging Devel
, vol.122
, pp. 1985-1995
-
-
De Luigi, A.1
Fragiacomo, C.2
Lucca, U.3
Quadri, P.4
Tettamanti, M.5
De Simoni, M.G.6
-
155
-
-
0025807206
-
Elevated circulating tumor necrosis factor levels in Alzheimer's disease
-
Fillit, H.; Ding, W.H.; Buee, L.; Kalman, J.; Altstiel, L.; Lawlor, B.; Wolf-Klein, G. Elevated circulating tumor necrosis factor levels in Alzheimer's disease. Neurosci. Lett., 1991, 129, 318-320.
-
(1991)
Neurosci. Lett
, vol.129
, pp. 318-320
-
-
Fillit, H.1
Ding, W.H.2
Buee, L.3
Kalman, J.4
Altstiel, L.5
Lawlor, B.6
Wolf-Klein, G.7
-
156
-
-
0036966388
-
Peripheral inflammatory response in Alzheimer's disease and multiinfarct dementia
-
De Luigi, A.; Pizzimenti, S.; Quadri, P.; Lucca, U.; Tettamanti, M.; Fragiacomo, C.; De Simoni, M.G.: Peripheral inflammatory response in Alzheimer's disease and multiinfarct dementia. Neurobiol. Dis., 2002, 11, 308-314.
-
(2002)
Neurobiol. Dis
, vol.11
, pp. 308-314
-
-
De Luigi, A.1
Pizzimenti, S.2
Quadri, P.3
Lucca, U.4
Tettamanti, M.5
Fragiacomo, C.6
De Simoni, M.G.7
-
157
-
-
0035134690
-
An independent non-neuronal cholinergic system in lymphocytes
-
Fuji, T.; Kawashima, K. An independent non-neuronal cholinergic system in lymphocytes. Jpn. J. Pharmacol., 2001, 85, 11-15.
-
(2001)
Jpn. J. Pharmacol
, vol.85
, pp. 11-15
-
-
Fuji, T.1
Kawashima, K.2
-
158
-
-
0037470634
-
A -induced TNF-α expression and acetylcholine action in mouse glial cells
-
Nomura, J.; Hosoi, T.; Okuma, Y.; Nomura, Y. A -induced TNF-α expression and acetylcholine action in mouse glial cells. Life Sci., 2003, 72, 2121-2126.
-
(2003)
Life Sci
, vol.72
, pp. 2121-2126
-
-
Nomura, J.1
Hosoi, T.2
Okuma, Y.3
Nomura, Y.4
-
159
-
-
0345086476
-
Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines
-
Sato, K.Z.; Fujii, T.; Watanabe, Y.; Yamada, S.; Ando, T.; Fujimoto, K.; Kawashima, K. Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines. Neurosci. Lett., 1999, 266, 17-20.
-
(1999)
Neurosci. Lett
, vol.266
, pp. 17-20
-
-
Sato, K.Z.1
Fujii, T.2
Watanabe, Y.3
Yamada, S.4
Ando, T.5
Fujimoto, K.6
Kawashima, K.7
-
160
-
-
0034104866
-
Extraneuronal cholinergic system in lymphocytes
-
Kawashima, K.; Fuji, T. Extraneuronal cholinergic system in lymphocytes. Pharmacol. Ther., 2000, 86, 29-48.
-
(2000)
Pharmacol. Ther
, vol.86
, pp. 29-48
-
-
Kawashima, K.1
Fuji, T.2
-
161
-
-
0037375479
-
Upregulation of mRNA encoding the M5 muscarinic acetylcholine receptor in human T- and B-lymphocytes during immunological responses
-
Fuji, T.; Watanebe,Y.; Inoue, T.; Kawashima, K. Upregulation of mRNA encoding the M5 muscarinic acetylcholine receptor in human T- and B-lymphocytes during immunological responses. Neurochem. Res., 2003, 28, 423-429.
-
(2003)
Neurochem. Res
, vol.28
, pp. 423-429
-
-
Fuji, T.1
Watanebe, Y.2
Inoue, T.3
Kawashima, K.4
-
162
-
-
0037300746
-
Differential nicotinic acetylcholine receptor subunit expression in the human hippocampus
-
Graham, A.J.; Ray, M.A.; Perry, E.K.; Jaros, E.; Perry, R.H.; Volsen, S.G.; Bose, S.; Evans, N.; Lindstrom, J.; Court, J.A. Differential nicotinic acetylcholine receptor subunit expression in the human hippocampus. J. Chem. Neuroanat., 2003, 25, 97-113.
-
(2003)
J. Chem. Neuroanat
, vol.25
, pp. 97-113
-
-
Graham, A.J.1
Ray, M.A.2
Perry, E.K.3
Jaros, E.4
Perry, R.H.5
Volsen, S.G.6
Bose, S.7
Evans, N.8
Lindstrom, J.9
Court, J.A.10
-
163
-
-
0034713266
-
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
-
Borovikova, L.V.; Ivanova, S.; Zhang, M.; Yang, H.; Botchkina, G.I.; Watidns, L.R.; Wang, H.; Abumrad, N.; Eaton, J.W.; Tracey, K.J. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature, 2000, 405, 458-462.
-
(2000)
Nature
, vol.405
, pp. 458-462
-
-
Borovikova, L.V.1
Ivanova, S.2
Zhang, M.3
Yang, H.4
Botchkina, G.I.5
Watidns, L.R.6
Wang, H.7
Abumrad, N.8
Eaton, J.W.9
Tracey, K.J.10
-
164
-
-
0037461768
-
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation
-
Wang, H.; Yu, M.; Ochani, M.; Amella, C.A.; Tanovic, M.; Susarla, S.; Li, J.H.; Wang, H.C.; Yang, H.; Ulloa, L.; Al Abed, Y.; Czura, C.J.; Tracey, K.J. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature, 2003, 421, 384-388.
-
(2003)
Nature
, vol.421
, pp. 384-388
-
-
Wang, H.1
Yu, M.2
Ochani, M.3
Amella, C.A.4
Tanovic, M.5
Susarla, S.6
Li, J.H.7
Wang, H.C.8
Yang, H.9
Ulloa, L.10
Al Abed, Y.11
Czura, C.J.12
Tracey, K.J.13
-
165
-
-
33645237919
-
Anti-inflammatory properties of cholinergic up-regulation: A new role for acetylcholinesterase inhibitors
-
Nizri, E.; Hamra-Amitay, Y.; Sicsic, C.; Lavon, I.; Brenner, T.
-
(2006)
Neuropharmacol
, vol.50
, pp. 540-547
-
-
Nizri, E.1
Hamra-Amitay, Y.2
Sicsic, C.3
Lavon, I.4
Brenner, T.5
-
166
-
-
47849132772
-
Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease
-
Reale, M.; Iarlori, C.; Feliciani, C.; Gambi D. Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease. J. Alzheimer's Dis., 2008, 14, 147-159.
-
(2008)
J. Alzheimer's Dis
, vol.14
, pp. 147-159
-
-
Reale, M.1
Iarlori, C.2
Feliciani, C.3
Gambi, D.4
-
167
-
-
0035196471
-
Reversible and irreversible acetylcholinesterase inhibitors cause changes in neuronal amyloid precursor protein processing and protein kinase C level in vitro
-
Pakaski, M.; Rakonczay, Z.; Kasa, P. Reversible and irreversible acetylcholinesterase inhibitors cause changes in neuronal amyloid precursor protein processing and protein kinase C level in vitro. Neurochem. Int., 2001, 38, 219-226.
-
(2001)
Neurochem. Int
, vol.38
, pp. 219-226
-
-
Pakaski, M.1
Rakonczay, Z.2
Kasa, P.3
-
168
-
-
0032080309
-
Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils
-
Alvarez, A.; Alarcon, R.; Opazo, C.; Campos, E.O.; Munoz, F.J.; Calderon, F.H.; Dajas, F.; Gentry, M.K.; Doctor, B.P.; De Mello, F.G.; Inestrosa, N.C. Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils. J. Neurosci., 1998, 18, 3213-3223.
-
(1998)
J. Neurosci
, vol.18
, pp. 3213-3223
-
-
Alvarez, A.1
Alarcon, R.2
Opazo, C.3
Campos, E.O.4
Munoz, F.J.5
Calderon, F.H.6
Dajas, F.7
Gentry, M.K.8
Doctor, B.P.9
De Mello, F.G.10
Inestrosa, N.C.11
-
169
-
-
2442672920
-
Alzheimer patients treated with an AChE inhibitor show higher IL-4 and lower IL-1β levels and expression in peripheral blood mononuclear cells
-
Gambi, F.; Reale, M.; Iarlori, C.; Salone, A.; Toma, L.; Paladini, C.; De Luca, G.; Feliciani, C.; Salvatore, M.; Salerno, R.M.; Theoharides, T.C.; Conti, P.; Exton, M.; Gambi, D. Alzheimer patients treated with an AChE inhibitor show higher IL-4 and lower IL-1β levels and expression in peripheral blood mononuclear cells. J. Clin. Psychopharmacol., 2004, 24, 314-21.
-
(2004)
J. Clin. Psychopharmacol
, vol.24
, pp. 314-321
-
-
Gambi, F.1
Reale, M.2
Iarlori, C.3
Salone, A.4
Toma, L.5
Paladini, C.6
De Luca, G.7
Feliciani, C.8
Salvatore, M.9
Salerno, R.M.10
Theoharides, T.C.11
Conti, P.12
Exton, M.13
Gambi, D.14
-
170
-
-
12144285619
-
IL-4 in vitro production is upregulated in Alzheimer's disease patients treated with acetylcholinesterase inhibitors
-
Lugaresi, A.; Di Iorio, A.; Iarlori, C.; Reale, M.; De Luca, G.; Sparvieri, E.; Michetti, A.; Conti, P.; Gambi, D.; Abate, G.; Paganelli, R. IL-4 in vitro production is upregulated in Alzheimer's disease patients treated with acetylcholinesterase inhibitors. Exp Gerontol., 2004, 39, 653-57.
-
(2004)
Exp Gerontol
, vol.39
, pp. 653-657
-
-
Lugaresi, A.1
Di Iorio, A.2
Iarlori, C.3
Reale, M.4
De Luca, G.5
Sparvieri, E.6
Michetti, A.7
Conti, P.8
Gambi, D.9
Abate, G.10
Paganelli, R.11
-
171
-
-
10744222732
-
Treatment with an acetylcholinesterase inhibitor in Alzheimer patients modulates the expression and production of the pro-inflammatory and anti-inflammatory cytokines
-
Reale, M.; Iarlori, C.; Gambi, F.; Feiciani, C.; Salone, A.; Toma, L.; De Luca, G.; Salvatore, M.; Conti, P.; Gambi, D. Treatment with an acetylcholinesterase inhibitor in Alzheimer patients modulates the expression and production of the pro-inflammatory and anti-inflammatory cytokines. J. Neuroimmunol., 2004, 148, 162-71.
-
(2004)
J. Neuroimmunol
, vol.148
, pp. 162-171
-
-
Reale, M.1
Iarlori, C.2
Gambi, F.3
Feiciani, C.4
Salone, A.5
Toma, L.6
De Luca, G.7
Salvatore, M.8
Conti, P.9
Gambi, D.10
-
172
-
-
23044465288
-
Expression and production of two selected betachemokines in peripheral blood mononuclear cells from patients with Alzheimer's disease
-
Iarlori, C.; Gambi, D.; Gambi, F.; Lucci, I; Feliciani, C.; Salvatore, M.; Reale, M. Expression and production of two selected betachemokines in peripheral blood mononuclear cells from patients with Alzheimer's disease. Exp. Gerontol., 2005, 40, 605-11.
-
(2005)
Exp. Gerontol
, vol.40
, pp. 605-611
-
-
Iarlori, C.1
Gambi, D.2
Gambi, F.3
Lucci, I.4
Feliciani, C.5
Salvatore, M.6
Reale, M.7
-
173
-
-
37249057800
-
Acetylcholinesterase and butyrylcholinesterase as possible markers of low-grade systemic inflammation
-
Das, U.N. Acetylcholinesterase and butyrylcholinesterase as possible markers of low-grade systemic inflammation. Med. Sci. Monit., 2007, 13, RA214-21.
-
(2007)
Med. Sci. Monit
, vol.13
-
-
Das, U.N.1
-
174
-
-
0037491975
-
Differential distribution of butyrylcholinesterase and acetylcholinesterase in the human thalamus
-
Darvesh, S.; Hopkins, D.A. Differential distribution of butyrylcholinesterase and acetylcholinesterase in the human thalamus. J. Comp. Neurol., 2003, 11, 463, 25-43.
-
(2003)
J. Comp. Neurol
, vol.11
, Issue.463
, pp. 25-43
-
-
Darvesh, S.1
Hopkins, D.A.2
-
175
-
-
0037318283
-
Neurobiology of butyrylcholinesterase
-
Darvesh, S.; Hopkins, D.A.; Geula, C. Neurobiology of butyrylcholinesterase. Nat. Rev. Neurosci., 2003, 4, 131-138.
-
(2003)
Nat. Rev. Neurosci
, vol.4
, pp. 131-138
-
-
Darvesh, S.1
Hopkins, D.A.2
Geula, C.3
-
176
-
-
4043074138
-
Cholinesterase inhibitors: New roles and therapeutic alternatives
-
Giacobini, E. Cholinesterase inhibitors: new roles and therapeutic alternatives. Pharmacol. Res., 2004, 50, 433-440.
-
(2004)
Pharmacol. Res
, vol.50
, pp. 433-440
-
-
Giacobini, E.1
-
177
-
-
0026794041
-
Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development - a study of molecular forms
-
Arendt, T.; Brückner, M.K.; Lange, M.; Bigl, V. Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development - a study of molecular forms. Neurochem. Int., 1992, 21, 381-396.
-
(1992)
Neurochem. Int
, vol.21
, pp. 381-396
-
-
Arendt, T.1
Brückner, M.K.2
Lange, M.3
Bigl, V.4
-
178
-
-
0023161530
-
Molecular forms of acetylcholinesterase and butyrylcholinesterase in human plasma and cerebrospinal fluid
-
Atack, J.R.; Perry, E.K.; Bonham, J.R.; Perry, R.H. Molecular forms of acetylcholinesterase and butyrylcholinesterase in human plasma and cerebrospinal fluid. J. Neurochem., 1987, 48, 1845-1850.
-
(1987)
J. Neurochem
, vol.48
, pp. 1845-1850
-
-
Atack, J.R.1
Perry, E.K.2
Bonham, J.R.3
Perry, R.H.4
-
179
-
-
0029863697
-
Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: Possible role of the peripheral site of the enzyme
-
Inestrosa, N.C.; Alvarez, A.; Pérez, C.A.; Moreno, R.D.; Vicente, M.; Linker, C.; Casanueva, O.I.; Soto, C.; Garrido, J. Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron, 1996, 16, 881-891.
-
(1996)
Neuron
, vol.16
, pp. 881-891
-
-
Inestrosa, N.C.1
Alvarez, A.2
Pérez, C.A.3
Moreno, R.D.4
Vicente, M.5
Linker, C.6
Casanueva, O.I.7
Soto, C.8
Garrido, J.9
-
180
-
-
4444365676
-
Pharmacotherapy in the treatment of Alzheimer's disease: An update
-
Leonard, B.E. Pharmacotherapy in the treatment of Alzheimer's disease: an update. World Psychiatry, 2004, 3, 84-88
-
(2004)
World Psychiatry
, vol.3
, pp. 84-88
-
-
Leonard, B.E.1
-
181
-
-
0028270519
-
A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group
-
Knapp, M.J.; Knopman, D.S.; Solomon, P.R.; Pendlebury, W.W.; Davis, C.S.; Gracon, S.I. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group. JAMA, 1994, 27, 985-991.
-
(1994)
JAMA
, vol.27
, pp. 985-991
-
-
Knapp, M.J.1
Knopman, D.S.2
Solomon, P.R.3
Pendlebury, W.W.4
Davis, C.S.5
Gracon, S.I.6
-
182
-
-
0034685887
-
Kinetic analysis of the toxicological effect of tacrine (Cognex®) on human retinal acetylcholinesterase activity
-
Alhomida, S.; Al-Rajhi, A.S.; Kamal, M.A.; Al-Jafari, A.A. Kinetic analysis of the toxicological effect of tacrine (Cognex®) on human retinal acetylcholinesterase activity. Toxicology, 2000, 147, 33-39.
-
(2000)
Toxicology
, vol.147
, pp. 33-39
-
-
Alhomida, S.1
Al-Rajhi, A.S.2
Kamal, M.A.3
Al-Jafari, A.A.4
-
183
-
-
0031637354
-
-
Al-Jafari, A.A.; Kamal, M.A.; Alhomida, A.S. Sensitivity of bovine retinal acetylcholinesterase (E.C. 3.1.1.7) toward tacrine: kinetic characterization. J. Biochem. Mol. Toxicol., 1998, 12, 245-251.
-
Al-Jafari, A.A.; Kamal, M.A.; Alhomida, A.S. Sensitivity of bovine retinal acetylcholinesterase (E.C. 3.1.1.7) toward tacrine: kinetic characterization. J. Biochem. Mol. Toxicol., 1998, 12, 245-251.
-
-
-
-
184
-
-
0034219406
-
Thermodynamic analysis of human retinal acetylcholinesterase inhibition using an anti-Alzheimer's drug, tacrine, through the development of a dual substrate and temperature model
-
Kamal, M.A.; Alhomida, A.S.; Al-Rajhi, A.A.; Al-Jafari, A.A. Thermodynamic analysis of human retinal acetylcholinesterase inhibition using an anti-Alzheimer's drug, tacrine, through the development of a dual substrate and temperature model. Proc. Natl. Sci. Coun. Repub. China B, 2000, 24, 108-115.
-
(2000)
Proc. Natl. Sci. Coun. Repub. China B
, vol.24
, pp. 108-115
-
-
Kamal, M.A.1
Alhomida, A.S.2
Al-Rajhi, A.A.3
Al-Jafari, A.A.4
-
185
-
-
0037111266
-
Patient populations in clinical trials of the efficacy and tolerability of donepezil in patients with vascular dementia
-
Pratt, R.D. Patient populations in clinical trials of the efficacy and tolerability of donepezil in patients with vascular dementia. J. Neurol. Sci., 2002, 20, 57-65.
-
(2002)
J. Neurol. Sci
, vol.20
, pp. 57-65
-
-
Pratt, R.D.1
-
186
-
-
43649099862
-
Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: An open-label, crossover, single-centre study
-
Shua-Haim, J.; Smith, J.; Picard, F.; Sedek, G.; Athalye, S.; Pommier, F.; Lefèvre, G. Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: an open-label, crossover, single-centre study. Clin. Drug Investig., 2008, 28, 361-374.
-
(2008)
Clin. Drug Investig
, vol.28
, pp. 361-374
-
-
Shua-Haim, J.1
Smith, J.2
Picard, F.3
Sedek, G.4
Athalye, S.5
Pommier, F.6
Lefèvre, G.7
-
188
-
-
0028301181
-
Pharmacokinetics and pharmacodynamics of metrifonate in humans
-
Unni, L.K.; Womack, C.; Hannant, M.E.; Becker, R.E. Pharmacokinetics and pharmacodynamics of metrifonate in humans. Methods Find. Exp. Clin. Pharmacol., 1994, 16, 285-289.
-
(1994)
Methods Find. Exp. Clin. Pharmacol
, vol.16
, pp. 285-289
-
-
Unni, L.K.1
Womack, C.2
Hannant, M.E.3
Becker, R.E.4
-
189
-
-
0034048390
-
Brain hypoplasia caused by exposure to trichlorfon and dichlorvos during development can be ascribed to DNA alkylation damage and inhibition of DNA alkyltransferase repair
-
Mehl, A.; Rolseth, V.; Gordon, S.; Bjoraas, M.; Seeberg, E.; Fonnum, F. Brain hypoplasia caused by exposure to trichlorfon and dichlorvos during development can be ascribed to DNA alkylation damage and inhibition of DNA alkyltransferase repair. Neurotoxicology, 2000, 21, 165-173.
-
(2000)
Neurotoxicology
, vol.21
, pp. 165-173
-
-
Mehl, A.1
Rolseth, V.2
Gordon, S.3
Bjoraas, M.4
Seeberg, E.5
Fonnum, F.6
-
190
-
-
0015361825
-
The alkylating properties of organophosphates
-
Bedford, C.T.; Robinson; J. The alkylating properties of organophosphates. Xenobiotic, 1972, 2, 307-337.
-
(1972)
Xenobiotic
, vol.2
, pp. 307-337
-
-
Bedford, C.T.1
Robinson, J.2
-
191
-
-
0001137761
-
Two organophosphorus compounds were studied, DDVP, and metrifonate (trichlorfon, O,Odimethyl2,2,2trichlorolhydroxyethylphosphonate)
-
Barthel, W.F.; Alexander, B.H.; Giang, P.A.; Hall, S.A. Two organophosphorus compounds were studied, DDVP, and metrifonate (trichlorfon, O,Odimethyl2,2,2trichlorolhydroxyethylphosphonate). J. Amer. Chem. Soc., 1955, 77, 2424-2455.
-
(1955)
J. Amer. Chem. Soc
, vol.77
, pp. 2424-2455
-
-
Barthel, W.F.1
Alexander, B.H.2
Giang, P.A.3
Hall, S.A.4
-
192
-
-
0142010609
-
Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid
-
Lovell, M.A.; Xie, C.; Xiong, S.; Markesbery, W.R. Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid. J. Alzheimers Dis., 2003, 5, 229-239.
-
(2003)
J. Alzheimers Dis
, vol.5
, pp. 229-239
-
-
Lovell, M.A.1
Xie, C.2
Xiong, S.3
Markesbery, W.R.4
-
193
-
-
0035955513
-
Alpha-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway
-
Zhang, L.; Xing, G.Q.; Barker, J.L.; Chang, Y.; Maric, D.; Ma, W.; Li, B.S.; Rubinow, D.R. Alpha-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway. Neurosci. Lett., 2001, 312, 125-128.
-
(2001)
Neurosci. Lett
, vol.312
, pp. 125-128
-
-
Zhang, L.1
Xing, G.Q.2
Barker, J.L.3
Chang, Y.4
Maric, D.5
Ma, W.6
Li, B.S.7
Rubinow, D.R.8
-
194
-
-
33746412987
-
RS-alpha-lipoic acid protects cholinergic cells against sodium nitroprusside and amyloid-beta neurotoxicity through restoration of acetyl-CoA level
-
Bielarczyk, H.; Gul, S.; Ronowska, A.; Bizon-Zygmanska, D.; Pawelczyk, T.; Szutowicz, A.R. RS-alpha-lipoic acid protects cholinergic cells against sodium nitroprusside and amyloid-beta neurotoxicity through restoration of acetyl-CoA level. J. Neurochem., 2006, 98, 1242-1251.
-
(2006)
J. Neurochem
, vol.98
, pp. 1242-1251
-
-
Bielarczyk, H.1
Gul, S.2
Ronowska, A.3
Bizon-Zygmanska, D.4
Pawelczyk, T.5
Szutowicz, A.R.6
-
195
-
-
33845713183
-
Lipoic acid as a novel treatment for Alzheimer's disease and related dementias
-
Holmquist, L.; Stuchbury, G.; Berbaum, K.; Muscat, S.; Young, S.; Hager, K.; Engel, J.; Münch, G. Lipoic acid as a novel treatment for Alzheimer's disease and related dementias. Pharmacol. Ther., 2007, 113, 154-164.
-
(2007)
Pharmacol. Ther
, vol.113
, pp. 154-164
-
-
Holmquist, L.1
Stuchbury, G.2
Berbaum, K.3
Muscat, S.4
Young, S.5
Hager, K.6
Engel, J.7
Münch, G.8
-
196
-
-
37049019288
-
Intracellular Ca2+ dynamics of hippocampal interneurons following nicotinic acetylcholine receptor activation
-
Szabo, S.I.; Zelles, T.; Lendvai, B. Intracellular Ca2+ dynamics of hippocampal interneurons following nicotinic acetylcholine receptor activation. Neurochem. Int., 2008, 52, 135-141.
-
(2008)
Neurochem. Int
, vol.52
, pp. 135-141
-
-
Szabo, S.I.1
Zelles, T.2
Lendvai, B.3
-
197
-
-
13444291352
-
Coupling of human nicotinic acetylcholine receptors α7 to calcium channels in GH3 cells
-
Feuerbach, D.; Lingenhöhl, K.; Dobbins, P.; Mosbacher, J.; Corbett, N.; Nozulak, J.; Hoyer, D. Coupling of human nicotinic acetylcholine receptors α7 to calcium channels in GH3 cells. Neuropharmacology, 2005, 48, 215-227.
-
(2005)
Neuropharmacology
, vol.48
, pp. 215-227
-
-
Feuerbach, D.1
Lingenhöhl, K.2
Dobbins, P.3
Mosbacher, J.4
Corbett, N.5
Nozulak, J.6
Hoyer, D.7
-
198
-
-
0043092171
-
Combination of serum markers related to several mechanisms in Alzheimer's disease
-
Teunissen, C.E.; Lütjohann, D.; von Bergmann, K.; Verhey, F.; Vreeling, F.; Wauters, A.; Bosmans; E.; Bosma, H.; van Boxtel, M.P.; Maes, M.; Delanghe, J.; Blom, H.J.; Verbeek, M.M.; Rieckmann, P.; De Bruijn, C.; Steinbusch, H.W.; de Vente, J. Combination of serum markers related to several mechanisms in Alzheimer's disease. Neurobiol. Aging, 2003, 24, 893-902.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 893-902
-
-
Teunissen, C.E.1
Lütjohann, D.2
von Bergmann, K.3
Verhey, F.4
Vreeling, F.5
Wauters, A.6
Bosmans, E.7
Bosma, H.8
van Boxtel, M.P.9
Maes, M.10
Delanghe, J.11
Blom, H.J.12
Verbeek, M.M.13
Rieckmann, P.14
De Bruijn, C.15
Steinbusch, H.W.16
de Vente, J.17
-
199
-
-
0028199942
-
Correlation of cytokine secretion by mononuclear cells of Alzheimer patients and their disease stage
-
Huberman, M.; Shalit, F.; Roth-Deri, I.; Gutman, B.; Brodie, C.; Kott, E.; Sredni, B.: Correlation of cytokine secretion by mononuclear cells of Alzheimer patients and their disease stage. J. Neuroimmunol., 1994, 52, 147-152.
-
(1994)
J. Neuroimmunol
, vol.52
, pp. 147-152
-
-
Huberman, M.1
Shalit, F.2
Roth-Deri, I.3
Gutman, B.4
Brodie, C.5
Kott, E.6
Sredni, B.7
-
200
-
-
0034704593
-
Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1
-
Gu, L.; Tseng, S.; Homer, R.M.; Tam, C.; Loda, M.; Rollins, B.J. Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1. Nature, 2000, 404, 407-411.
-
(2000)
Nature
, vol.404
, pp. 407-411
-
-
Gu, L.1
Tseng, S.2
Homer, R.M.3
Tam, C.4
Loda, M.5
Rollins, B.J.6
-
201
-
-
0031948073
-
Secretion of TH-2-type cytokines by acetylcholine receptor (AChR)-stimulated mononuclear cells
-
Ragheb, S.; Lisak, R.P. Secretion of TH-2-type cytokines by acetylcholine receptor (AChR)-stimulated mononuclear cells. Ann. N.Y. Acad. Sci., 1998, 841, 347-350.
-
(1998)
Ann. N.Y. Acad. Sci
, vol.841
, pp. 347-350
-
-
Ragheb, S.1
Lisak, R.P.2
-
202
-
-
0027197996
-
Neuroprotective role of IL-4 against activated microglia
-
Chao, C.C.; Molitor, T.W; Hu, S. Neuroprotective role of IL-4 against activated microglia. J. Immunol., 1993, 151, 1473-1481.
-
(1993)
J. Immunol
, vol.151
, pp. 1473-1481
-
-
Chao, C.C.1
Molitor, T.W.2
Hu, S.3
-
203
-
-
0033230204
-
Neuronal death in cytokine-activated primary human brain cell culture: Role of tumor necrosis factor-alpha
-
Downen, M.; Amaral, T.D.; Hua, L.L.; Zhao, M.L.; Lee, S.C. Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-alpha. Glia, 1999, 28, 114-127.
-
(1999)
Glia
, vol.28
, pp. 114-127
-
-
Downen, M.1
Amaral, T.D.2
Hua, L.L.3
Zhao, M.L.4
Lee, S.C.5
-
204
-
-
0035131536
-
Roles of muscarinic acetylcholine receptors in interleukin-2 synthesis in lymphocytes
-
Okuma, Y.; Nomura, Y. Roles of muscarinic acetylcholine receptors in interleukin-2 synthesis in lymphocytes. Jpn. J. Pharmacol., 2001, 85, 16-19.
-
(2001)
Jpn. J. Pharmacol
, vol.85
, pp. 16-19
-
-
Okuma, Y.1
Nomura, Y.2
-
205
-
-
0032571352
-
Synthesis of acetylcholine and expression of mRNA for muscarinic receptor subtypes in T-lymphocytes
-
Kawashima, K.; Fujii, T.; Watanabe, Y.; Misawa, H. Synthesis of acetylcholine and expression of mRNA for muscarinic receptor subtypes in T-lymphocytes. Life Sci., 1998, 62, 1701-1705.
-
(1998)
Life Sci
, vol.62
, pp. 1701-1705
-
-
Kawashima, K.1
Fujii, T.2
Watanabe, Y.3
Misawa, H.4
-
206
-
-
0027457818
-
Presence of m3 subtype muscarinic acetylcholine receptors and receptor-mediated increases in the cytoplasmic concentration of Ca2+ in Jurkat, a human leukemic helper T lymphocyte line
-
Kaneda, T.; Kitamura, Y.; Nomura, Y. Presence of m3 subtype muscarinic acetylcholine receptors and receptor-mediated increases in the cytoplasmic concentration of Ca2+ in Jurkat, a human leukemic helper T lymphocyte line. Mol. Pharmacol., 1993, 43, 356-364
-
(1993)
Mol. Pharmacol
, vol.43
, pp. 356-364
-
-
Kaneda, T.1
Kitamura, Y.2
Nomura, Y.3
-
207
-
-
0030976493
-
Stimulatory roles of muscarinic acetylcholine receptors on T cell antigen receptor/ CD3 complex-mediated interleukin-2 production in human peripheral blood lymphocytes
-
Fujino, H.; Kitamura, Y.; Yada, T.; Uehara, T. Nomura, Y. Stimulatory roles of muscarinic acetylcholine receptors on T cell antigen receptor/ CD3 complex-mediated interleukin-2 production in human peripheral blood lymphocytes. Mol. Pharmacol., 1997, 51, 1007-1014.
-
(1997)
Mol. Pharmacol
, vol.51
, pp. 1007-1014
-
-
Fujino, H.1
Kitamura, Y.2
Yada, T.3
Uehara, T.4
Nomura, Y.5
-
208
-
-
0019410439
-
The parallel, time-dependent, bimodal change in lymphocyte cholinergic binding activity and cholinergic influence upon lymphocyte-mediated cytotoxicity after lymphocyte activation
-
Strom, B.T.; Lane, A.M.; George, K. The parallel, time-dependent, bimodal change in lymphocyte cholinergic binding activity and cholinergic influence upon lymphocyte-mediated cytotoxicity after lymphocyte activation. J. Immunol., 1981, 127, 705-710.
-
(1981)
J. Immunol
, vol.127
, pp. 705-710
-
-
Strom, B.T.1
Lane, A.M.2
George, K.3
-
209
-
-
0036993145
-
Butyrylcholinesterase: An important new target in Alzheimer's disease therapy
-
Greig, N.H.; Lahiri, D.K.; Sambamurti, K. Butyrylcholinesterase: an important new target in Alzheimer's disease therapy. Int. Psychogeriatr., 2002, 14, 77-91.
-
(2002)
Int. Psychogeriatr
, vol.14
, pp. 77-91
-
-
Greig, N.H.1
Lahiri, D.K.2
Sambamurti, K.3
-
210
-
-
26044437911
-
The cholinergic anti-inflammatory pathway
-
Pavlov, V.A.; Tracey, K.J. The cholinergic anti-inflammatory pathway. Brain Behav. Immun., 2005, 19, 493-499.
-
(2005)
Brain Behav. Immun
, vol.19
, pp. 493-499
-
-
Pavlov, V.A.1
Tracey, K.J.2
-
211
-
-
0037470635
-
Introduction: The nonneuronal cholinergic system in humans
-
Grando, S.A; Kawashima, K.; Wessler, I. Introduction: the nonneuronal cholinergic system in humans. Life Sci., 2003, 72, 2009-2012.
-
(2003)
Life Sci
, vol.72
, pp. 2009-2012
-
-
Grando, S.A.1
Kawashima, K.2
Wessler, I.3
-
212
-
-
0037608959
-
Muscarinic acetylcholine receptors regulating cell cycle progression are expressed in human gingival keratinocytes
-
Arredondo, J.; Hall, L.L.; Ndoye, A.; Chernyavsky, A.I.; Jolkovsky, D.L.; Grando, S.A. Muscarinic acetylcholine receptors regulating cell cycle progression are expressed in human gingival keratinocytes. J. Periodontal. Res., 2003, 38, 79-89.
-
(2003)
J. Periodontal. Res
, vol.38
, pp. 79-89
-
-
Arredondo, J.1
Hall, L.L.2
Ndoye, A.3
Chernyavsky, A.I.4
Jolkovsky, D.L.5
Grando, S.A.6
-
213
-
-
0037470632
-
Keratinocyte acetylcholine receptors regulate cell adhesion
-
Nguyen, V.T.; Arredondo, J.; Chernyavsky, A.I.; Kitajima, Y.; Grando, S.A. Keratinocyte acetylcholine receptors regulate cell adhesion. Life Sci., 2003, 72, 2081-85.
-
(2003)
Life Sci
, vol.72
, pp. 2081-2085
-
-
Nguyen, V.T.1
Arredondo, J.2
Chernyavsky, A.I.3
Kitajima, Y.4
Grando, S.A.5
-
214
-
-
55049094829
-
Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling
-
Parrish, W.R.; Rosas-Ballina, M.; Gallowitsch-Puerta, M.; Ochani, M.; Ochani, K.; Hudson, L.Q.; Lin, X.; Patel, N.; Johnson, S.M.; Chavan, S.; Goldstein, R.; Czura, C.J.; Miller, E.J.; Al-Abed, Y.; Tracey, K.J.; Pavlov, V.A. Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling. Mol. Med., 2008, 14, 567-574.
-
(2008)
Mol. Med
, vol.14
, pp. 567-574
-
-
Parrish, W.R.1
Rosas-Ballina, M.2
Gallowitsch-Puerta, M.3
Ochani, M.4
Ochani, K.5
Hudson, L.Q.6
Lin, X.7
Patel, N.8
Johnson, S.M.9
Chavan, S.10
Goldstein, R.11
Czura, C.J.12
Miller, E.J.13
Al-Abed, Y.14
Tracey, K.J.15
Pavlov, V.A.16
-
215
-
-
0027966134
-
Complement C1q does not bind monomeric beta-amyloid
-
Snyder, S.W.; Wang, G.T.; Barrett, L.; Ladror, U.S.; Casuto, D.; Lee, C.M.; Krafft, G.A.; Holzman, R.B.; Holzman, T.F. Complement C1q does not bind monomeric beta-amyloid. Exp. Neurol., 1994, 128, 136-142.
-
(1994)
Exp. Neurol
, vol.128
, pp. 136-142
-
-
Snyder, S.W.1
Wang, G.T.2
Barrett, L.3
Ladror, U.S.4
Casuto, D.5
Lee, C.M.6
Krafft, G.A.7
Holzman, R.B.8
Holzman, T.F.9
-
216
-
-
0031777185
-
Cyclooxygenases 1 and 2
-
Vane, J.R.; Bakhle, Y.S.; Botting, R.M. Cyclooxygenases 1 and 2. Annu. Rev. Pharmacol. Toxicol., 1998, 38, 97-120.
-
(1998)
Annu. Rev. Pharmacol. Toxicol
, vol.38
, pp. 97-120
-
-
Vane, J.R.1
Bakhle, Y.S.2
Botting, R.M.3
-
217
-
-
0034535351
-
Cholinesterase inhibitors stabilize Alzheimer's disease
-
Giacobini, E. Cholinesterase inhibitors stabilize Alzheimer's disease. Ann. N.Y. Acad. Sci., 2000, 920, 321-327.
-
(2000)
Ann. N.Y. Acad. Sci
, vol.920
, pp. 321-327
-
-
Giacobini, E.1
-
218
-
-
22144442723
-
Editorial: Advances in Alzheimer therapy: something old, something new, something borrowed, something blue
-
Greig, N.H.; Lahiri, D.K.; Giacobini, E. Editorial: advances in Alzheimer therapy: something old, something new, something borrowed, something blue. Curr. Alzheimer Res., 2005, 2, 275-279.
-
(2005)
Curr. Alzheimer Res
, vol.2
, pp. 275-279
-
-
Greig, N.H.1
Lahiri, D.K.2
Giacobini, E.3
-
219
-
-
35748931165
-
A new acetylcholinesterase inhibitor with anti-PAF activity modulates oxidative stress and pro-inflammatory mediators release in stimulated RAW 264.7 macrophage cells. Comparison with tacrine
-
Ezoulin, M.J.; Liu, Z.; Dutertre-Catella, H.; Wu, G.; Dong, C.Z.; Heymans, F.; Ombetta, J.E.; Rat, P.; Massicot, F. A new acetylcholinesterase inhibitor with anti-PAF activity modulates oxidative stress and pro-inflammatory mediators release in stimulated RAW 264.7 macrophage cells. Comparison with tacrine. Int. Immunopharmacol., 2007, 7, 1685-1694.
-
(2007)
Int. Immunopharmacol
, vol.7
, pp. 1685-1694
-
-
Ezoulin, M.J.1
Liu, Z.2
Dutertre-Catella, H.3
Wu, G.4
Dong, C.Z.5
Heymans, F.6
Ombetta, J.E.7
Rat, P.8
Massicot, F.9
-
220
-
-
0032507596
-
Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells
-
Svensson, A.L.; Nordberg, A. Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells. Neuroreport., 1998, 9, 1519-1522.
-
(1998)
Neuroreport
, vol.9
, pp. 1519-1522
-
-
Svensson, A.L.1
Nordberg, A.2
-
221
-
-
0034284410
-
Huperzine A and tacrine attenuate beta-amyloid peptide-induced oxidative injury
-
Xiao, X.Q.; Wang, R.; Tang, X.C. Huperzine A and tacrine attenuate beta-amyloid peptide-induced oxidative injury. J. Neurosci. Res., 2000, 61, 564-69.
-
(2000)
J. Neurosci. Res
, vol.61
, pp. 564-569
-
-
Xiao, X.Q.1
Wang, R.2
Tang, X.C.3
-
222
-
-
39549086775
-
Mitochondrial reactive oxygen species inactivate neuronal nicotinic acetylcholine receptors and induce long-term depression of fast nicotinic synaptic transmission
-
Campanucci, V.A.; Krishnaswamy, A.; Cooper, E. Mitochondrial reactive oxygen species inactivate neuronal nicotinic acetylcholine receptors and induce long-term depression of fast nicotinic synaptic transmission. J. Neurosci., 2008, 28, 1733-1744.
-
(2008)
J. Neurosci
, vol.28
, pp. 1733-1744
-
-
Campanucci, V.A.1
Krishnaswamy, A.2
Cooper, E.3
-
223
-
-
48549100286
-
Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases
-
Roy, A.; Jana, A.; Yatish, K.; Freidt, M.B.; Fung, Y.K.; Martinson, J.A.; Pahan, K. Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases. Free Radic. Biol. Med., 2008, 45, 686-699.
-
(2008)
Free Radic. Biol. Med
, vol.45
, pp. 686-699
-
-
Roy, A.1
Jana, A.2
Yatish, K.3
Freidt, M.B.4
Fung, Y.K.5
Martinson, J.A.6
Pahan, K.7
-
224
-
-
0346398206
-
Neural inhibition of inflammation: The cholinergic anti-inflammatory pathway
-
Czura, J.C.; Friedman, S. G.; Tracey, K. J. Neural inhibition of inflammation: the cholinergic anti-inflammatory pathway. J. Endotoxin Res., 2003, 9, 409-413.
-
(2003)
J. Endotoxin Res
, vol.9
, pp. 409-413
-
-
Czura, J.C.1
Friedman, S.G.2
Tracey, K.J.3
-
225
-
-
0142178155
-
The cholinergic anti-inflammatory pathway: A missing link in neuroimmunomodulation
-
Pavlov, V. A.; Wang, H.; Czura, C. J.; Friedman, S. G.; Tracey,. K. J. The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation. Mol. Med., 2003, 9, 125-134.
-
(2003)
Mol. Med
, vol.9
, pp. 125-134
-
-
Pavlov, V.A.1
Wang, H.2
Czura, C.J.3
Friedman, S.G.4
Tracey, K.J.5
-
226
-
-
34249283363
-
Expression and function of genes encoding cholinergic components in murine immune cells
-
Kawashima, K.; Yoshikawa, K.; Fujii, Y.; Moriwaki,Y. Expression and function of genes encoding cholinergic components in murine immune cells. Life Sci., 2007, 80, 2314-2319.
-
(2007)
Life Sci
, vol.80
, pp. 2314-2319
-
-
Kawashima, K.1
Yoshikawa, K.2
Fujii, Y.3
Moriwaki, Y.4
|