Mitochondrial reactive oxygen species inactivate neuronal nicotinic acetylcholine receptors and induce long-term depression of fast nicotinic synaptic transmission

Journal of Neuroscience

Volumn 28, Issue 7, 2008, Pages 1733-1744

  Campanucci, Verónica A ^a   Krishnaswamy, Arjun ^a   Cooper, Ellis ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Antimycin A; Autonomic nervous system; Desensitization; Fenton reaction; Mitochondrial ROS; Nerve growth factor; Oxidative stress; Sympathetic neurons

Indexed keywords

MEMBRANE PROTEIN; NICOTINIC RECEPTOR; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; DEGENERATIVE DISEASE; ELECTRON TRANSPORT; LONG TERM DEPRESSION; MITOCHONDRIAL MEMBRANE; MOUSE; NERVE CELL; NEWBORN; NONHUMAN; OXIDATIVE PHOSPHORYLATION; POSTGANGLIONIC NERVE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; EVOKED RESPONSE; METABOLISM; MITOCHONDRION; PHYSIOLOGY; SUPERIOR CERVICAL GANGLION;

ANIMALS; CELLS, CULTURED; CYTOSOL; EVOKED POTENTIALS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NEURONS; REACTIVE OXYGEN SPECIES; RECEPTORS, NICOTINIC; SUPERIOR CERVICAL GANGLION; SYNAPTIC TRANSMISSION;

EID: 39549086775     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5130-07.2008     Document Type: Article

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