Hepatocyte nuclear factor 4α regulation of bile acid and drug metabolism

Expert Opinion on Drug Metabolism and Toxicology

Volumn 5, Issue 2, 2009, Pages 137-147

  Chiang, John Y L ^a  

^a Northeastern Ohio Medical University   (United States)

Author keywords

Bile acid metabolism; Cytochrome p450; Diabetes; Drug metabolism; Lipid metabolism; Nuclear receptors

Indexed keywords

BILE ACID; CHOLESTEROL; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; FATTY ACID; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MULTIDRUG RESISTANCE PROTEIN 2; PHENOBARBITAL; STEROID; XENOBIOTIC AGENT;

BILE ACID SYNTHESIS; BILIARY EXCRETION; CHOLESTASIS; DIABETES MELLITUS; DRUG DETOXIFICATION; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG TRANSPORT; DYSLIPIDEMIA; ENZYME ACTIVITY; HUMAN; INTESTINE; INTESTINE ABSORPTION; LIPID ABSORPTION; LIPID METABOLISM; LIVER; LIVER CELL; METABOLITE; MOLECULE; NUTRIENT; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; TISSUE; XENOBIOTIC METABOLISM;

ANIMALS; BILE ACIDS AND SALTS; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; LIPID METABOLISM; LIVER; MUTATION; PHARMACEUTICAL PREPARATIONS; SIGNAL TRANSDUCTION;

EID: 67649120490     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425250802707342     Document Type: Review

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