Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

Structure

Volumn 10, Issue 9, 2002, Pages 1225-1234

  Wisely, G Bruce ^a   Miller, Ann B ^a   Davis, Roderick G ^a   Thornquest, Alan D ^a   Johnson, Robert ^a   Spitzer, Tim ^a   Sefler, Andrea ^a   Shearer, Barry ^a   Moore, John T ^a   Miller, Aaron B ^a   Willson, Timothy M ^a   Williams, Shawn P ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Diabetes; Fatty acids; HNF4; MODY; Nuclear receptor; Transcription factor

Indexed keywords

BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; FATTY ACID; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, HUMAN; HNF4G PROTEIN, HUMAN; ISOPROTEIN; MLX PROTEIN, HUMAN; PHOSPHOPROTEIN; TRANSCRIPTION FACTOR; CELL NUCLEUS RECEPTOR; CHLOROFORM; FATTY ACID BINDING PROTEIN; LIGAND; METHANOL; PALMITIC ACID;

AMINO ACID SEQUENCE; ARTICLE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; GENETIC TRANSCRIPTION; HUMAN; MASS FRAGMENTOGRAPHY; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY; ANIMAL CELL; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GAS CHROMATOGRAPHY; GENETIC TRANSFECTION; ISOTOPE LABELING; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; FATTY ACIDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ISOFORMS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0036710140     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00829-8     Document Type: Article

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