A common P2 promoter polymorphism of the hepatocyte nuclear factor-4α gene is associated with insulin secretion in non-obese Japanese with type 2 diabetes

Endocrine Journal

Volumn 55, Issue 6, 2008, Pages 999-1004

  Tokunaga, Ayumi ^a   Horikawa, Yukio ^b   Fukuda Akita, Etsuko ^a   Okita, Kohei ^a   Iwahashi, Hiromi ^a   Shimomura, Iichiro ^a   Takeda, Jun ^b   Yamagata, Kazuya ^c  

^a OSAKA UNIVERSITY   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

Author keywords

HNF 4 ; Insulin; Single nucleotide polymorphism; Type 2 diabetes

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 4ALPHA; INSULIN;

ADULT; AGE DISTRIBUTION; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RELEASE; JAPANESE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PROMOTER REGION; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; INSULIN; JAPAN; LINKAGE (GENETICS); MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC;

EID: 58549105718     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K08E-083     Document Type: Article

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