The MODY1 gene HNF-4α regulates selected genes involved in insulin secretion

Journal of Clinical Investigation

Volumn 115, Issue 4, 2005, Pages 1006-1015

  Gupta, Rana K ^a   Vatamaniuk, Marko Z ^a   Lee, Catherine S ^a   Flaschen, Reed C ^a   Fulmer, James T ^a   Matschinsky, Franz M ^a   Duncan, Stephen A ^b   Kaestner, Klaus H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; INSULIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; SULFONYLUREA DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; GENE; GENE CONTROL; GENE DELETION; GENE MUTATION; GENE TARGETING; GENETIC TRANSFECTION; GLUCOSE HOMEOSTASIS; HNF 4ALPHA GENE; HYPERINSULINEMIA; IMAGING; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; KIR6.2 GENE; KNOCKOUT GENE; LOXP SITE; MATURITY ONSET DIABETES MELLITUS; MATURITY ONSET DIABETES OF THE YOUNG; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; CALCIUM; DIABETES MELLITUS, TYPE 2; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TOLERANCE TEST; GLYBURIDE; HEPATOCYTE NUCLEAR FACTOR 4; HYPERINSULINISM; HYPOGLYCEMIC AGENTS; INSULIN; ISLETS OF LANGERHANS; MICE; MICE, KNOCKOUT; PHOSPHOPROTEINS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROMOTER REGIONS (GENETICS); PROTEIN SUBUNITS; TRANSCRIPTION FACTORS;

EID: 16844366885     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200522365     Document Type: Article

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