Transcriptional regulation of the human sterol 12α-hydroxylase gene (CYP8B1): Roles of hepatocyte nuclear factor 4α in mediating bile acid repression

Journal of Biological Chemistry

Volumn 276, Issue 45, 2001, Pages 41690-41699

  Zhang, Ming ^b   Chiang, John Y L ^a  

^a NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; CELLS; CHOLESTEROL; DNA; ENZYMES; GENES; INSULIN;

TRANSCRIPTION;

BIOCHEMISTRY;

BILE ACID; CELL NUCLEUS RECEPTOR; CHOLESTEROL 12ALPHA HYDROXYLASE; CHOLESTEROL 7ALPHA MONOOXYGENASE; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LUCIFERASE; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CELL RECEPTOR; CYTOCHROME P450; DNA BINDING PROTEIN; HNF4A PROTEIN, HUMAN; MLX PROTEIN, HUMAN; PHOSPHOPROTEIN; REPRESSOR PROTEIN; SMALL HETERODIMER PARTNER PROTEIN; STEROID 12ALPHA MONOOXYGENASE; STEROID MONOOXYGENASE; TCFL4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ARTICLE; BILE ACID RESPONSIVE ELEMENT; BILE ACID SYNTHESIS; BILE SECRETION; BINDING SITE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYP8B1 GENE; DNA RESPONSIVE ELEMENT; EMBRYO; ENZYME MECHANISM; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE ACTIVITY; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENETIC TRANSCRIPTION; HORMONE ACTION; HUMAN; HUMAN CELL; HYBRID; LIPOGENESIS; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN FAMILY; PROTEIN FUNCTION; REPORTER GENE; SITE DIRECTED MUTAGENESIS; TRANSACTIVATION; TRANSCRIPTION REGULATION; CELL CULTURE; GENETICS; MOLECULAR GENETICS; PHYSIOLOGY;

MAMMALIA;

BASE SEQUENCE; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BILE ACIDS AND SALTS; BINDING SITES; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CYTOCHROME P-450 ENZYME SYSTEM; DNA-BINDING PROTEINS; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; STEROID 12-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0035834771     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105117200     Document Type: Article

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