메뉴 건너뛰기




Volumn 96, Issue 3, 2009, Pages 321-337

Remodeling the clock: Coactivators and signal transduction in the circadian clockworks

Author keywords

Biological rhythms; Chromatin remodeling; Circadian clock; Signal transduction; Timing of transcription

Indexed keywords

CIRCADIAN RHYTHM; FLY; GENOME; HOMOLOGY; MAMMAL; PHYSIOLOGY; PROTEIN;

EID: 61449098418     PISSN: 00281042     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00114-008-0474-9     Document Type: Review
Times cited : (19)

References (160)
  • 1
    • 0034654095 scopus 로고    scopus 로고
    • Involvement of the MAP kinase cascade in resetting of the mammalian circadian clock
    • M Akashi E Nishida 2000 Involvement of the MAP kinase cascade in resetting of the mammalian circadian clock Genes Dev 14 645 649
    • (2000) Genes Dev , vol.14 , pp. 645-649
    • Akashi, M.1    Nishida, E.2
  • 4
    • 20144382764 scopus 로고    scopus 로고
    • A GABAergic mechanism is necessary for coupling dissociable ventral and dorsal regional oscillators within the circadian clock
    • H Albus MJ Vansteensel S Michel GD Block JH Meijer 2005 A GABAergic mechanism is necessary for coupling dissociable ventral and dorsal regional oscillators within the circadian clock Curr Biol 15 886 893
    • (2005) Curr Biol , vol.15 , pp. 886-893
    • Albus, H.1    Vansteensel, M.J.2    Michel, S.3    Block, G.D.4    Meijer, J.H.5
  • 7
    • 33846102215 scopus 로고    scopus 로고
    • Regulating a circadian clock's period, phase and amplitude by phosphorylation: Insights from Drosophila
    • K Bae I Edery 2006 Regulating a circadian clock's period, phase and amplitude by phosphorylation: insights from Drosophila J Biochem (Tokyo) 140 609 617
    • (2006) J Biochem (Tokyo) , vol.140 , pp. 609-617
    • Bae, K.1    Edery, I.2
  • 10
    • 0033119313 scopus 로고    scopus 로고
    • The Drosophila dCREB2 gene affects the circadian clock
    • MP Belvin H Zhou JC Yin 1999 The Drosophila dCREB2 gene affects the circadian clock Neuron 22 777 787
    • (1999) Neuron , vol.22 , pp. 777-787
    • Belvin, M.P.1    Zhou, H.2    Yin, J.C.3
  • 11
    • 33847787932 scopus 로고    scopus 로고
    • PDP1epsilon functions downstream of the circadian oscillator to mediate behavioral rhythms
    • J Benito H Zheng PE Hardin 2007 PDP1epsilon functions downstream of the circadian oscillator to mediate behavioral rhythms J Neurosci 27 2539 2547
    • (2007) J Neurosci , vol.27 , pp. 2539-2547
    • Benito, J.1    Zheng, H.2    Hardin, P.E.3
  • 12
    • 0033544692 scopus 로고    scopus 로고
    • Cycling vrille expression is required for a functional Drosophila clock
    • J Blau MW Young 1999 Cycling vrille expression is required for a functional Drosophila clock Cell 99 661 671
    • (1999) Cell , vol.99 , pp. 661-671
    • Blau, J.1    Young, M.W.2
  • 14
    • 41049088736 scopus 로고    scopus 로고
    • Interlocked feedback loops of the circadian clock of Neurospora crassa
    • M Brunner K Kaldi 2008 Interlocked feedback loops of the circadian clock of Neurospora crassa Mol Microbiol 68 255 262
    • (2008) Mol Microbiol , vol.68 , pp. 255-262
    • Brunner, M.1    Kaldi, K.2
  • 18
    • 46249098507 scopus 로고    scopus 로고
    • The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock
    • JC Chiu JT Vanselow A Kramer I Edery 2008 The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock Genes Dev 22 1758 1772
    • (2008) Genes Dev , vol.22 , pp. 1758-1772
    • Chiu, J.C.1    Vanselow, J.T.2    Kramer, A.3    Edery, I.4
  • 20
    • 0025816190 scopus 로고
    • NMDA receptor antagonists block the effects of light on circadian behavior in the mouse
    • CS Colwell RG Foster M Menaker 1991 NMDA receptor antagonists block the effects of light on circadian behavior in the mouse Brain Res 554 105 110
    • (1991) Brain Res , vol.554 , pp. 105-110
    • Colwell, C.S.1    Foster, R.G.2    Menaker, M.3
  • 21
    • 0029861755 scopus 로고    scopus 로고
    • E2F inhibits transcriptional activation by the retinoic acid receptor
    • SL Costa MA Pratt MW McBurney 1996 E2F inhibits transcriptional activation by the retinoic acid receptor Cell Growth Differ 7 1479 1485
    • (1996) Cell Growth Differ , vol.7 , pp. 1479-1485
    • Costa, S.L.1    Pratt, M.A.2    McBurney, M.W.3
  • 24
    • 20044390202 scopus 로고    scopus 로고
    • The DOUBLE-TIME protein kinase regulates the subcellular localization of the Drosophila clock protein PERIOD
    • SA Cyran G Yiannoulos AM Buchsbaum L Saez MW Young J Blau 2005 The DOUBLE-TIME protein kinase regulates the subcellular localization of the Drosophila clock protein PERIOD J Neurosci 25 5430 5437
    • (2005) J Neurosci , vol.25 , pp. 5430-5437
    • Cyran, S.A.1    Yiannoulos, G.2    Buchsbaum, A.M.3    Saez, L.4    Young, M.W.5    Blau, J.6
  • 25
    • 0033637383 scopus 로고    scopus 로고
    • Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
    • F Damiola N Le Minh N Preitner B Kornmann F Fleury-Olela U Schibler 2000 Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus Genes Dev 14 2950 2961
    • (2000) Genes Dev , vol.14 , pp. 2950-2961
    • Damiola, F.1    Le Minh, N.2    Preitner, N.3    Kornmann, B.4    Fleury-Olela, F.5    Schibler, U.6
  • 27
    • 0028580097 scopus 로고
    • Resetting the biological clock: Mediation of nocturnal circadian shifts by glutamate and NO
    • JM Ding D Chen ET Weber LE Faiman MA Rea MU Gillette 1994 Resetting the biological clock: mediation of nocturnal circadian shifts by glutamate and NO Science 266 1713 1717
    • (1994) Science , vol.266 , pp. 1713-1717
    • Ding, J.M.1    Chen, D.2    Weber, E.T.3    Faiman, L.E.4    Rea, M.A.5    Gillette, M.U.6
  • 28
    • 0031012135 scopus 로고    scopus 로고
    • Resetting the biological clock: Mediation of nocturnal CREB phosphorylation via light, glutamate, and nitric oxide
    • JM Ding LE Faiman WJ Hurst LR Kuriashkina MU Gillette 1997 Resetting the biological clock: mediation of nocturnal CREB phosphorylation via light, glutamate, and nitric oxide J Neurosci 17 667 675
    • (1997) J Neurosci , vol.17 , pp. 667-675
    • Ding, J.M.1    Faiman, L.E.2    Hurst, W.J.3    Kuriashkina, L.R.4    Gillette, M.U.5
  • 29
    • 33646145721 scopus 로고    scopus 로고
    • Circadian regulator CLOCK is a histone acetyltransferase
    • M Doi J Hirayama P Sassone-Corsi 2006 Circadian regulator CLOCK is a histone acetyltransferase Cell 125 497 508
    • (2006) Cell , vol.125 , pp. 497-508
    • Doi, M.1    Hirayama, J.2    Sassone-Corsi, P.3
  • 30
    • 45249115128 scopus 로고    scopus 로고
    • The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism
    • H Duez B Staels 2008 The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism Diab Vasc Dis Res 5 82 88
    • (2008) Diab Vasc Dis Res , vol.5 , pp. 82-88
    • Duez, H.1    Staels, B.2
  • 31
    • 0026048367 scopus 로고
    • Regularly scheduled voluntary exercise synchronizes the mouse circadian clock
    • DM Edgar WC Dement 1991 Regularly scheduled voluntary exercise synchronizes the mouse circadian clock Am J Physiol 261 R928 R933
    • (1991) Am J Physiol , vol.261
    • Edgar, D.M.1    Dement, W.C.2
  • 32
    • 0037053314 scopus 로고    scopus 로고
    • The circadian regulatory proteins BMAL1 and cryptochromes are substrates of CASEIN KINASE Iepsilon
    • EJ Eide EL Vielhaber WA Hinz DM Virshup 2002 The circadian regulatory proteins BMAL1 and cryptochromes are substrates of CASEIN KINASE Iepsilon J Biol Chem 277 17248 17254
    • (2002) J Biol Chem , vol.277 , pp. 17248-17254
    • Eide, E.J.1    Vielhaber, E.L.2    Hinz, W.A.3    Virshup, D.M.4
  • 34
    • 0037426839 scopus 로고    scopus 로고
    • Rhythmic histone acetylation underlies transcription in the mammalian circadian clock
    • JP Etchegaray C Lee PA Wade SM Reppert 2003 Rhythmic histone acetylation underlies transcription in the mammalian circadian clock Nature 421 177 182
    • (2003) Nature , vol.421 , pp. 177-182
    • Etchegaray, J.P.1    Lee, C.2    Wade, P.A.3    Reppert, S.M.4
  • 35
    • 34250790719 scopus 로고    scopus 로고
    • Post-translational regulation of the Drosophila circadian clock requires PROTEIN PHOSPHATASE 1 (PP1)
    • Y Fang S Sathyanarayanan A Sehgal 2007 Post-translational regulation of the Drosophila circadian clock requires PROTEIN PHOSPHATASE 1 (PP1) Genes Dev 21 1506 1518
    • (2007) Genes Dev , vol.21 , pp. 1506-1518
    • Fang, Y.1    Sathyanarayanan, S.2    Sehgal, A.3
  • 36
    • 0037020198 scopus 로고    scopus 로고
    • The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo
    • L Fu H Pelicano J Liu P Huang C Lee 2002 The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo Cell 111 41 50
    • (2002) Cell , vol.111 , pp. 41-50
    • Fu, L.1    Pelicano, H.2    Liu, J.3    Huang, P.4    Lee, C.5
  • 37
    • 24144459585 scopus 로고    scopus 로고
    • The molecular clock mediates leptin-regulated bone formation
    • L Fu MS Patel A Bradley EF Wagner G Karsenty 2005 The molecular clock mediates leptin-regulated bone formation Cell 122 803 815
    • (2005) Cell , vol.122 , pp. 803-815
    • Fu, L.1    Patel, M.S.2    Bradley, A.3    Wagner, E.F.4    Karsenty, G.5
  • 38
    • 6344221991 scopus 로고    scopus 로고
    • The mammalian circadian timing system: From gene expression to physiology
    • F Gachon E Nagoshi SA Brown J Ripperger U Schibler 2004 The mammalian circadian timing system: from gene expression to physiology Chromosoma 113 103 112
    • (2004) Chromosoma , vol.113 , pp. 103-112
    • Gachon, F.1    Nagoshi, E.2    Brown, S.A.3    Ripperger, J.4    Schibler, U.5
  • 39
    • 33847779219 scopus 로고    scopus 로고
    • Post-translational modifications regulate the ticking of the circadian clock
    • M Gallego DM Virshup 2007 Post-translational modifications regulate the ticking of the circadian clock Nat Rev Mol Cell Biol 8 139 148
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 139-148
    • Gallego, M.1    Virshup, D.M.2
  • 40
    • 33749360459 scopus 로고    scopus 로고
    • PROTEIN PHOSPHATASE 1 regulates the stability of the circadian protein PER2
    • M Gallego H Kang DM Virshup 2006 PROTEIN PHOSPHATASE 1 regulates the stability of the circadian protein PER2 Biochem J 399 169 175
    • (2006) Biochem J , vol.399 , pp. 169-175
    • Gallego, M.1    Kang, H.2    Virshup, D.M.3
  • 41
    • 33749016793 scopus 로고    scopus 로고
    • Waking experience affects sleep need in Drosophila
    • I Ganguly-Fitzgerald J Donlea PJ Shaw 2006 Waking experience affects sleep need in Drosophila Science 313 1775 1781
    • (2006) Science , vol.313 , pp. 1775-1781
    • Ganguly-Fitzgerald, I.1    Donlea, J.2    Shaw, P.J.3
  • 44
    • 0034234237 scopus 로고    scopus 로고
    • CBP/p300 in cell growth, transformation, and development
    • RH Goodman S Smolik 2000 CBP/p300 in cell growth, transformation, and development Genes Dev 14 1553 1577
    • (2000) Genes Dev , vol.14 , pp. 1553-1577
    • Goodman, R.H.1    Smolik, S.2
  • 46
    • 7244252844 scopus 로고    scopus 로고
    • Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain
    • B Grima E Chelot R Xia F Rouyer 2004 Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain Nature 431 869 873
    • (2004) Nature , vol.431 , pp. 869-873
    • Grima, B.1    Chelot, E.2    Xia, R.3    Rouyer, F.4
  • 47
    • 24744436847 scopus 로고    scopus 로고
    • Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by GLYCOGEN SYNTHASE KINASE-3 beta
    • Y Harada M Sakai N Kurabayashi T Hirota Y Fukada 2005 Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by GLYCOGEN SYNTHASE KINASE-3 beta J Biol Chem 280 31714 31721
    • (2005) J Biol Chem , vol.280 , pp. 31714-31721
    • Harada, Y.1    Sakai, M.2    Kurabayashi, N.3    Hirota, T.4    Fukada, Y.5
  • 48
    • 24044444531 scopus 로고    scopus 로고
    • The circadian timekeeping system of Drosophila
    • PE Hardin 2005 The circadian timekeeping system of Drosophila Curr Biol 15 R714 R722
    • (2005) Curr Biol , vol.15
    • Hardin, P.E.1
  • 51
    • 36249006061 scopus 로고    scopus 로고
    • Intracellular Ca2+ regulates free-running circadian clock oscillation in vivo
    • MC Harrisingh Y Wu GA Lnenicka MN Nitabach 2007 Intracellular Ca2+ regulates free-running circadian clock oscillation in vivo J Neurosci 27 12489 12499
    • (2007) J Neurosci , vol.27 , pp. 12489-12499
    • Harrisingh, M.C.1    Wu, Y.2    Lnenicka, G.A.3    Nitabach, M.N.4
  • 52
    • 36348961277 scopus 로고    scopus 로고
    • Circadian clocks: Regulators of endocrine and metabolic rhythms
    • M Hastings JS O'Neill ES Maywood 2007 Circadian clocks: regulators of endocrine and metabolic rhythms J Endocrinol 195 187 198
    • (2007) J Endocrinol , vol.195 , pp. 187-198
    • Hastings, M.1    O'Neill, J.S.2    Maywood, E.S.3
  • 53
    • 0037039784 scopus 로고    scopus 로고
    • Melanopsin-containing retinal ganglion cells: Architecture, projections, and intrinsic photosensitivity
    • S Hattar HW Liao M Takao DM Berson KW Yau 2002 Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity Science 295 1065 1070
    • (2002) Science , vol.295 , pp. 1065-1070
    • Hattar, S.1    Liao, H.W.2    Takao, M.3    Berson, D.M.4    Yau, K.W.5
  • 54
    • 14744303401 scopus 로고    scopus 로고
    • Neurobiology of the fruit fly's circadian clock
    • C Helfrich-Förster 2005 Neurobiology of the fruit fly's circadian clock Genes Brain Behav 4 65 76
    • (2005) Genes Brain Behav , vol.4 , pp. 65-76
    • Helfrich-Förster, C.1
  • 55
    • 0035025621 scopus 로고    scopus 로고
    • The circadian clock of fruit flies is blind after elimination of all known photoreceptors
    • C Helfrich-Förster C Winter A Hofbauer JC Hall R Stanewsky 2001 The circadian clock of fruit flies is blind after elimination of all known photoreceptors Neuron 30 249 261
    • (2001) Neuron , vol.30 , pp. 249-261
    • Helfrich-Förster, C.1    Winter, C.2    Hofbauer, A.3    Hall, J.C.4    Stanewsky, R.5
  • 59
    • 33644605957 scopus 로고    scopus 로고
    • Drosophila CLOCK is constitutively expressed in circadian oscillator and non-oscillator cells
    • JH Houl W Yu SM Dudek PE Hardin 2006 Drosophila CLOCK is constitutively expressed in circadian oscillator and non-oscillator cells J Biol Rhythms 21 93 103
    • (2006) J Biol Rhythms , vol.21 , pp. 93-103
    • Houl, J.H.1    Yu, W.2    Dudek, S.M.3    Hardin, P.E.4
  • 60
    • 35748969132 scopus 로고    scopus 로고
    • Circadian transcription depends on limiting amounts of the transcription co-activator NEJIRE/CBP
    • HC Hung C Maurer SA Kay F Weber 2007 Circadian transcription depends on limiting amounts of the transcription co-activator NEJIRE/CBP J Biol Chem 282 31349 31357
    • (2007) J Biol Chem , vol.282 , pp. 31349-31357
    • Hung, H.C.1    Maurer, C.2    Kay, S.A.3    Weber, F.4
  • 62
    • 23844460834 scopus 로고    scopus 로고
    • A role for GLYCOGEN SYNTHASE KINASE-3beta in the mammalian circadian clock
    • C Iitaka K Miyazaki T Akaike N Ishida 2005 A role for GLYCOGEN SYNTHASE KINASE-3beta in the mammalian circadian clock J Biol Chem 280 29397 29402
    • (2005) J Biol Chem , vol.280 , pp. 29397-29402
    • Iitaka, C.1    Miyazaki, K.2    Akaike, T.3    Ishida, N.4
  • 63
    • 0141676679 scopus 로고    scopus 로고
    • Regulation of inhibitory synaptic transmission by vasoactive intestinal peptide (VIP) in the mouse suprachiasmatic nucleus
    • J Itri CS Colwell 2003 Regulation of inhibitory synaptic transmission by vasoactive intestinal peptide (VIP) in the mouse suprachiasmatic nucleus J Neurophysiol 90 1589 1597
    • (2003) J Neurophysiol , vol.90 , pp. 1589-1597
    • Itri, J.1    Colwell, C.S.2
  • 64
    • 34347382964 scopus 로고    scopus 로고
    • CLOCKWORK ORANGE is a transcriptional repressor and a new Drosophila circadian pacemaker component
    • S Kadener D Stoleru M McDonald P Nawathean M Rosbash 2007 CLOCKWORK ORANGE is a transcriptional repressor and a new Drosophila circadian pacemaker component Genes Dev 21 1675 1686
    • (2007) Genes Dev , vol.21 , pp. 1675-1686
    • Kadener, S.1    Stoleru, D.2    McDonald, M.3    Nawathean, P.4    Rosbash, M.5
  • 65
    • 45149085615 scopus 로고    scopus 로고
    • Circadian transcription contributes to core period determination in Drosophila
    • S Kadener JS Menet R Schoer M Rosbash 2008 Circadian transcription contributes to core period determination in Drosophila PLoS Biol 6 e119
    • (2008) PLoS Biol , vol.6 , pp. 119
    • Kadener, S.1    Menet, J.S.2    Schoer, R.3    Rosbash, M.4
  • 68
    • 36349013781 scopus 로고    scopus 로고
    • Minireview: The neuroendocrinology of the suprachiasmatic nucleus as a conductor of body time in mammals
    • IN Karatsoreos R Silver 2007 Minireview: the neuroendocrinology of the suprachiasmatic nucleus as a conductor of body time in mammals Endocrinology 148 5640 5647
    • (2007) Endocrinology , vol.148 , pp. 5640-5647
    • Karatsoreos, I.N.1    Silver, R.2
  • 69
    • 33646591926 scopus 로고    scopus 로고
    • Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein
    • EY Kim I Edery 2006 Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein Proc Natl Acad Sci USA 103 6178 6183
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6178-6183
    • Kim, E.Y.1    Edery, I.2
  • 70
    • 0037187636 scopus 로고    scopus 로고
    • Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity
    • EY Kim K Bae FS Ng NR Glossop PE Hardin I Edery 2002 Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity Neuron 34 69 81
    • (2002) Neuron , vol.34 , pp. 69-81
    • Kim, E.Y.1    Bae, K.2    Ng, F.S.3    Glossop, N.R.4    Hardin, P.E.5    Edery, I.6
  • 71
    • 48349122032 scopus 로고    scopus 로고
    • Activating per repressor through a DBT-directed phosphorylation switch
    • S Kivimae L Saez MW Young 2008 Activating PER repressor through a DBT-directed phosphorylation switch PLoS Biol 6 e183
    • (2008) PLoS Biol , vol.6 , pp. 183
    • Kivimae, S.1    Saez, L.2    Young, M.W.3
  • 72
    • 0034964474 scopus 로고    scopus 로고
    • Phosphorylation of PERIOD is influenced by cycling physical associations of DOUBLE-TIME, PERIOD, and TIMELESS in the Drosophila clock
    • B Kloss A Rothenfluh MW Young L Saez 2001 Phosphorylation of PERIOD is influenced by cycling physical associations of DOUBLE-TIME, PERIOD, and TIMELESS in the Drosophila clock Neuron 30 699 706
    • (2001) Neuron , vol.30 , pp. 699-706
    • Kloss, B.1    Rothenfluh, A.2    Young, M.W.3    Saez, L.4
  • 73
    • 0037069671 scopus 로고    scopus 로고
    • Role for SLIMB in the degradation of Drosophila PERIOD protein phosphorylated by DOUBLETIME
    • HW Ko J Jiang I Edery 2002 Role for SLIMB in the degradation of Drosophila PERIOD protein phosphorylated by DOUBLETIME Nature 420 673 678
    • (2002) Nature , vol.420 , pp. 673-678
    • Ko, H.W.1    Jiang, J.2    Edery, I.3
  • 74
    • 33745503975 scopus 로고    scopus 로고
    • JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS
    • K Koh X Zheng A Sehgal 2006 JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS Science 312 1809 1812
    • (2006) Science , vol.312 , pp. 1809-1812
    • Koh, K.1    Zheng, X.2    Sehgal, A.3
  • 75
    • 34547134725 scopus 로고    scopus 로고
    • Circadian proteins in the regulation of cell cycle and genotoxic stress responses
    • RV Kondratov MP Antoch 2007 Circadian proteins in the regulation of cell cycle and genotoxic stress responses Trends Cell Biol 17 311 317
    • (2007) Trends Cell Biol , vol.17 , pp. 311-317
    • Kondratov, R.V.1    Antoch, M.P.2
  • 76
    • 0042626226 scopus 로고    scopus 로고
    • BMAL1-dependent circadian oscillation of nuclear CLOCK: Posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
    • RV Kondratov MV Chernov AA Kondratova VY Gorbacheva AV Gudkov MP Antoch 2003 BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system Genes Dev 17 1921 1932
    • (2003) Genes Dev , vol.17 , pp. 1921-1932
    • Kondratov, R.V.1    Chernov, M.V.2    Kondratova, A.A.3    Gorbacheva, V.Y.4    Gudkov, A.V.5    Antoch, M.P.6
  • 77
    • 0015119210 scopus 로고
    • Clock mutants of Drosophila melanogaster
    • RJ Konopka S Benzer 1971 Clock mutants of Drosophila melanogaster Proc Natl Acad Sci USA 68 2112 2116
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 2112-2116
    • Konopka, R.J.1    Benzer, S.2
  • 78
    • 16844367590 scopus 로고    scopus 로고
    • A screen for secreted factors of the suprachiasmatic nucleus
    • A Kramer FC Yang S Kraves CJ Weitz 2005 A screen for secreted factors of the suprachiasmatic nucleus Methods Enzymol 393 645 663
    • (2005) Methods Enzymol , vol.393 , pp. 645-663
    • Kramer, A.1    Yang, F.C.2    Kraves, S.3    Weitz, C.J.4
  • 79
    • 31544474606 scopus 로고    scopus 로고
    • A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity
    • S Kraves CJ Weitz 2006 A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity Nat Neurosci 9 212 219
    • (2006) Nat Neurosci , vol.9 , pp. 212-219
    • Kraves, S.1    Weitz, C.J.2
  • 80
    • 26944456961 scopus 로고    scopus 로고
    • A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior
    • BC Lear CE Merrill JM Lin A Schroeder L Zhang R Allada 2005 A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior Neuron 48 221 227
    • (2005) Neuron , vol.48 , pp. 221-227
    • Lear, B.C.1    Merrill, C.E.2    Lin, J.M.3    Schroeder, A.4    Zhang, L.5    Allada, R.6
  • 81
    • 0032191902 scopus 로고    scopus 로고
    • The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex
    • C Lee K Bae I Edery 1998 The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex Neuron 21 857 867
    • (1998) Neuron , vol.21 , pp. 857-867
    • Lee, C.1    Bae, K.2    Edery, I.3
  • 82
    • 0032778040 scopus 로고    scopus 로고
    • PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: A basis for circadian transcription
    • C Lee K Bae I Edery 1999 PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription Mol Cell Biol 19 5316 5325
    • (1999) Mol Cell Biol , vol.19 , pp. 5316-5325
    • Lee, C.1    Bae, K.2    Edery, I.3
  • 84
    • 52649158231 scopus 로고    scopus 로고
    • Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex
    • J Lee Y Lee MJ Lee E Park SH Kang CH Chung KH Lee K Kim 2008 Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex Mol Cell Biol 28 6056 6065
    • (2008) Mol Cell Biol , vol.28 , pp. 6056-6065
    • Lee, J.1    Lee, Y.2    Lee, M.J.3    Park, E.4    Kang, S.H.5    Chung, C.H.6    Lee, K.H.7    Kim, K.8
  • 85
    • 0027996648 scopus 로고
    • Altered circadian pacemaker functions and cyclic AMP rhythms in the Drosophila learning mutant dunce
    • JD Levine CI Casey DD Kalderon FR Jackson 1994 Altered circadian pacemaker functions and cyclic AMP rhythms in the Drosophila learning mutant dunce Neuron 13 967 974
    • (1994) Neuron , vol.13 , pp. 967-974
    • Levine, J.D.1    Casey, C.I.2    Kalderon, D.D.3    Jackson, F.R.4
  • 86
    • 0037032832 scopus 로고    scopus 로고
    • Resetting the circadian clock by social experience in Drosophila melanogaster
    • JD Levine P Funes HB Dowse JC Hall 2002 Resetting the circadian clock by social experience in Drosophila melanogaster Science 298 2010 2012
    • (2002) Science , vol.298 , pp. 2010-2012
    • Levine, J.D.1    Funes, P.2    Dowse, H.B.3    Hall, J.C.4
  • 88
    • 34347332369 scopus 로고    scopus 로고
    • Functional role of CREB-binding protein in the circadian clock system of Drosophila melanogaster
    • C Lim J Lee C Choi J Kim E Doh J Choe 2007 Functional role of CREB-binding protein in the circadian clock system of Drosophila melanogaster Mol Cell Biol 27 4876 4890
    • (2007) Mol Cell Biol , vol.27 , pp. 4876-4890
    • Lim, C.1    Lee, J.2    Choi, C.3    Kim, J.4    Doh, E.5    Choe, J.6
  • 90
    • 4544363312 scopus 로고    scopus 로고
    • The neuropeptide pigment-dispersing factor coordinates pacemaker interactions in the Drosophila circadian system
    • Y Lin GD Stormo PH Taghert 2004 The neuropeptide pigment-dispersing factor coordinates pacemaker interactions in the Drosophila circadian system J Neurosci 24 7951 7957
    • (2004) J Neurosci , vol.24 , pp. 7951-7957
    • Lin, Y.1    Stormo, G.D.2    Taghert, P.H.3
  • 91
    • 0035875069 scopus 로고    scopus 로고
    • A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock
    • S Martinek S Inonog AS Manoukian MW Young 2001 A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock Cell 105 769 779
    • (2001) Cell , vol.105 , pp. 769-779
    • Martinek, S.1    Inonog, S.2    Manoukian, A.S.3    Young, M.W.4
  • 93
    • 0141889955 scopus 로고    scopus 로고
    • Control mechanism of the circadian clock for timing of cell division in vivo
    • T Matsuo S Yamaguchi S Mitsui A Emi F Shimoda H Okamura 2003 Control mechanism of the circadian clock for timing of cell division in vivo Science 302 255 259
    • (2003) Science , vol.302 , pp. 255-259
    • Matsuo, T.1    Yamaguchi, S.2    Mitsui, S.3    Emi, A.4    Shimoda, F.5    Okamura, H.6
  • 94
    • 0035977158 scopus 로고    scopus 로고
    • Microarray analysis and organization of circadian gene expression in Drosophila
    • MJ McDonald M Rosbash 2001 Microarray analysis and organization of circadian gene expression in Drosophila Cell 107 567 578
    • (2001) Cell , vol.107 , pp. 567-578
    • McDonald, M.J.1    Rosbash, M.2
  • 96
    • 30844466208 scopus 로고    scopus 로고
    • PER-TIM interactions in living Drosophila cells: An interval timer for the circadian clock
    • P Meyer L Saez MW Young 2006 PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock Science 311 226 229
    • (2006) Science , vol.311 , pp. 226-229
    • Meyer, P.1    Saez, L.2    Young, M.W.3
  • 97
    • 33645528922 scopus 로고    scopus 로고
    • Why life oscillates-from a topographical towards a functional chronobiology
    • M Moser M Fruhwirth R Penter R Winker 2006 Why life oscillates-from a topographical towards a functional chronobiology Cancer Causes Control 17 591 599
    • (2006) Cancer Causes Control , vol.17 , pp. 591-599
    • Moser, M.1    Fruhwirth, M.2    Penter, R.3    Winker, R.4
  • 98
    • 0033543596 scopus 로고    scopus 로고
    • A role for the proteasome in the light response of the TIMELESS clock protein
    • N Naidoo W Song M Hunter-Ensor A Sehgal 1999 A role for the proteasome in the light response of the TIMELESS clock protein Science 285 1737 1741
    • (1999) Science , vol.285 , pp. 1737-1741
    • Naidoo, N.1    Song, W.2    Hunter-Ensor, M.3    Sehgal, A.4
  • 100
    • 0034629226 scopus 로고    scopus 로고
    • Localization of calcitonin receptor mRNA in the mouse brain: Coexistence with serotonin transporter mRNA
    • H Nakamoto Y Soeda S Takami M Minami M Satoh 2000 Localization of calcitonin receptor mRNA in the mouse brain: coexistence with serotonin transporter mRNA Brain Res Mol Brain Res 76 93 102
    • (2000) Brain Res Mol Brain Res , vol.76 , pp. 93-102
    • Nakamoto, H.1    Soeda, Y.2    Takami, S.3    Minami, M.4    Satoh, M.5
  • 101
    • 0036456125 scopus 로고    scopus 로고
    • Vasoactive intestinal polypeptide induces per1 and per2 gene expression in the rat suprachiasmatic nucleus late at night
    • HS Nielsen J Hannibal J Fahrenkrug 2002 Vasoactive intestinal polypeptide induces per1 and per2 gene expression in the rat suprachiasmatic nucleus late at night Eur J Neurosci 15 570 574
    • (2002) Eur J Neurosci , vol.15 , pp. 570-574
    • Nielsen, H.S.1    Hannibal, J.2    Fahrenkrug, J.3
  • 102
    • 38149026267 scopus 로고    scopus 로고
    • Organization of the Drosophila circadian control circuit
    • MN Nitabach PH Taghert 2008 Organization of the Drosophila circadian control circuit Curr Biol 18 R84 R93
    • (2008) Curr Biol , vol.18
    • Nitabach, M.N.1    Taghert, P.H.2
  • 103
    • 0037123779 scopus 로고    scopus 로고
    • Electrical silencing of Drosophila pacemaker neurons stops the free-running circadian clock
    • MN Nitabach J Blau TC Holmes 2002 Electrical silencing of Drosophila pacemaker neurons stops the free-running circadian clock Cell 109 485 495
    • (2002) Cell , vol.109 , pp. 485-495
    • Nitabach, M.N.1    Blau, J.2    Holmes, T.C.3
  • 105
    • 0032250181 scopus 로고    scopus 로고
    • Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei
    • K Obrietan S Impey DR Storm 1998 Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei Nat Neurosci 1 693 700
    • (1998) Nat Neurosci , vol.1 , pp. 693-700
    • Obrietan, K.1    Impey, S.2    Storm, D.R.3
  • 106
    • 34447637430 scopus 로고    scopus 로고
    • Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease
    • PN Pallier ES Maywood Z Zheng JE Chesham AN Inyushkin R Dyball MH Hastings AJ Morton 2007 Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease J Neurosci 27 7869 7878
    • (2007) J Neurosci , vol.27 , pp. 7869-7878
    • Pallier, P.N.1    Maywood, E.S.2    Zheng, Z.3    Chesham, J.E.4    Inyushkin, A.N.5    Dyball, R.6    Hastings, M.H.7    Morton, A.J.8
  • 109
    • 0037149498 scopus 로고    scopus 로고
    • Diurnal modulation of pacemaker potentials and calcium current in the mammalian circadian clock
    • CM Pennartz MT de Jeu NP Bos J Schaap AM Geurtsen 2002 Diurnal modulation of pacemaker potentials and calcium current in the mammalian circadian clock Nature 416 286 290
    • (2002) Nature , vol.416 , pp. 286-290
    • Pennartz, C.M.1    De Jeu, M.T.2    Bos, N.P.3    Schaap, J.4    Geurtsen, A.M.5
  • 110
    • 33751204172 scopus 로고    scopus 로고
    • Veela defines a molecular link between CRYPTOCHROME and TIMELESS in the light-input pathway to Drosophila's circadian clock
    • N Peschel S Veleri R Stanewsky 2006 Veela defines a molecular link between CRYPTOCHROME and TIMELESS in the light-input pathway to Drosophila's circadian clock Proc Natl Acad Sci USA 103 17313 17318
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17313-17318
    • Peschel, N.1    Veleri, S.2    Stanewsky, R.3
  • 111
    • 0036434287 scopus 로고    scopus 로고
    • Human clock genes
    • HD Piggins 2002 Human clock genes Ann Med 34 394 400
    • (2002) Ann Med , vol.34 , pp. 394-400
    • Piggins, H.D.1
  • 112
    • 0030656411 scopus 로고    scopus 로고
    • Independent photoreceptive circadian clocks throughout Drosophila
    • JD Plautz M Kaneko JC Hall SA Kay 1997 Independent photoreceptive circadian clocks throughout Drosophila Science 278 1632 1635
    • (1997) Science , vol.278 , pp. 1632-1635
    • Plautz, J.D.1    Kaneko, M.2    Hall, J.C.3    Kay, S.A.4
  • 113
    • 0037178787 scopus 로고    scopus 로고
    • The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator
    • N Preitner F Damiola L Lopez-Molina J Zakany D Duboule U Albrecht U Schibler 2002 The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator Cell 110 251 260
    • (2002) Cell , vol.110 , pp. 251-260
    • Preitner, N.1    Damiola, F.2    Lopez-Molina, L.3    Zakany, J.4    Duboule, D.5    Albrecht, U.6    Schibler, U.7
  • 114
    • 0032503969 scopus 로고    scopus 로고
    • Double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation
    • JL Price J Blau A Rothenfluh M Abodeely B Kloss MW Young 1998 double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation Cell 94 83 95
    • (1998) Cell , vol.94 , pp. 83-95
    • Price, J.L.1    Blau, J.2    Rothenfluh, A.3    Abodeely, M.4    Kloss, B.5    Young, M.W.6
  • 115
    • 0035478069 scopus 로고    scopus 로고
    • Glutamate blocks serotonergic phase advances of the mammalian circadian pacemaker through AMPA and NMDA receptors
    • RA Prosser 2001 Glutamate blocks serotonergic phase advances of the mammalian circadian pacemaker through AMPA and NMDA receptors J Neurosci 21 7815 7822
    • (2001) J Neurosci , vol.21 , pp. 7815-7822
    • Prosser, R.A.1
  • 116
    • 0024724634 scopus 로고
    • CGMP induces phase shifts of a mammalian circadian pacemaker at night, in antiphase to cAMP effects
    • RA Prosser AJ McArthur MU Gillette 1989 cGMP induces phase shifts of a mammalian circadian pacemaker at night, in antiphase to cAMP effects Proc Natl Acad Sci USA 86 6812 6815
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 6812-6815
    • Prosser, R.A.1    McArthur, A.J.2    Gillette, M.U.3
  • 118
    • 0033599009 scopus 로고    scopus 로고
    • A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila
    • SC Renn JH Park M Rosbash JC Hall PH Taghert 1999 A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila Cell 99 791 802
    • (1999) Cell , vol.99 , pp. 791-802
    • Renn, S.C.1    Park, J.H.2    Rosbash, M.3    Hall, J.C.4    Taghert, P.H.5
  • 119
    • 40849106529 scopus 로고    scopus 로고
    • The CLOCKWORK ORANGE Drosophila protein functions as both an activator and a repressor of clock gene expression
    • B Richier C Michard-Vanhee A Lamouroux C Papin F Rouyer 2008 The CLOCKWORK ORANGE Drosophila protein functions as both an activator and a repressor of clock gene expression J Biol Rhythms 23 103 116
    • (2008) J Biol Rhythms , vol.23 , pp. 103-116
    • Richier, B.1    Michard-Vanhee, C.2    Lamouroux, A.3    Papin, C.4    Rouyer, F.5
  • 120
    • 0141453190 scopus 로고    scopus 로고
    • Cryptochrome, compound eyes, Hofbauer-Buchner eyelets, and ocelli play different roles in the entrainment and masking pathway of the locomotor activity rhythm in the fruit fly Drosophila melanogaster
    • D Rieger R Stanewsky C Helfrich-Förster 2003 Cryptochrome, compound eyes, Hofbauer-Buchner eyelets, and ocelli play different roles in the entrainment and masking pathway of the locomotor activity rhythm in the fruit fly Drosophila melanogaster J Biol Rhythms 18 377 391
    • (2003) J Biol Rhythms , vol.18 , pp. 377-391
    • Rieger, D.1    Stanewsky, R.2    Helfrich-Förster, C.3
  • 121
    • 33645646764 scopus 로고    scopus 로고
    • Functional analysis of circadian pacemaker neurons in Drosophila melanogaster
    • D Rieger OT Shafer K Tomioka C Helfrich-Förster 2006 Functional analysis of circadian pacemaker neurons in Drosophila melanogaster J Neurosci 26 2531 2543
    • (2006) J Neurosci , vol.26 , pp. 2531-2543
    • Rieger, D.1    Shafer, O.T.2    Tomioka, K.3    Helfrich-Förster, C.4
  • 122
    • 33644617485 scopus 로고    scopus 로고
    • Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions
    • JA Ripperger U Schibler 2006 Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions Nat Genet 38 369 374
    • (2006) Nat Genet , vol.38 , pp. 369-374
    • Ripperger, J.A.1    Schibler, U.2
  • 123
    • 0034597629 scopus 로고    scopus 로고
    • Short-period mutations of per affect a double-time-dependent step in the Drosophila circadian clock
    • A Rothenfluh M Abodeely MW Young 2000 Short-period mutations of per affect a double-time-dependent step in the Drosophila circadian clock Curr Biol 10 1399 1402
    • (2000) Curr Biol , vol.10 , pp. 1399-1402
    • Rothenfluh, A.1    Abodeely, M.2    Young, M.W.3
  • 124
    • 0033711617 scopus 로고    scopus 로고
    • A TIMELESS-independent function for PERIOD proteins in the Drosophila clock
    • A Rothenfluh MW Young L Saez 2000 A TIMELESS-independent function for PERIOD proteins in the Drosophila clock Neuron 26 505 514
    • (2000) Neuron , vol.26 , pp. 505-514
    • Rothenfluh, A.1    Young, M.W.2    Saez, L.3
  • 126
    • 0037016665 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase phosphorylates and negatively regulates basic helix-loop-helix-PAS transcription factor BMAL1
    • K Sanada T Okano Y Fukada 2002 Mitogen-activated protein kinase phosphorylates and negatively regulates basic helix-loop-helix-PAS transcription factor BMAL1 J Biol Chem 277 267 271
    • (2002) J Biol Chem , vol.277 , pp. 267-271
    • Sanada, K.1    Okano, T.2    Fukada, Y.3
  • 127
    • 1342285689 scopus 로고    scopus 로고
    • Posttranslational regulation of Drosophila PERIOD protein by PROTEIN PHOSPHATASE 2A
    • S Sathyanarayanan X Zheng R Xiao A Sehgal 2004 Posttranslational regulation of Drosophila PERIOD protein by PROTEIN PHOSPHATASE 2A Cell 116 603 615
    • (2004) Cell , vol.116 , pp. 603-615
    • Sathyanarayanan, S.1    Zheng, X.2    Xiao, R.3    Sehgal, A.4
  • 129
    • 15044341917 scopus 로고    scopus 로고
    • Cellular oscillators: Rhythmic gene expression and metabolism
    • U Schibler F Naef 2005 Cellular oscillators: rhythmic gene expression and metabolism Curr Opin Cell Biol 17 223 229
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 223-229
    • Schibler, U.1    Naef, F.2
  • 130
    • 0037101628 scopus 로고    scopus 로고
    • Sequential nuclear accumulation of the clock proteins PERIOD and TIMELESS in the pacemaker neurons of Drosophila melanogaster
    • OT Shafer M Rosbash JW Truman 2002 Sequential nuclear accumulation of the clock proteins PERIOD and TIMELESS in the pacemaker neurons of Drosophila melanogaster J Neurosci 22 5946 5954
    • (2002) J Neurosci , vol.22 , pp. 5946-5954
    • Shafer, O.T.1    Rosbash, M.2    Truman, J.W.3
  • 131
    • 42149175153 scopus 로고    scopus 로고
    • Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging
    • OT Shafer DJ Kim R Dunbar-Yaffe VO Nikolaev MJ Lohse PH Taghert 2008 Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging Neuron 58 223 237
    • (2008) Neuron , vol.58 , pp. 223-237
    • Shafer, O.T.1    Kim, D.J.2    Dunbar-Yaffe, R.3    Nikolaev, V.O.4    Lohse, M.J.5    Taghert, P.H.6
  • 132
    • 0037118054 scopus 로고    scopus 로고
    • Stress response genes protect against lethal effects of sleep deprivation in Drosophila
    • PJ Shaw G Tononi RJ Greenspan DF Robinson 2002 Stress response genes protect against lethal effects of sleep deprivation in Drosophila Nature 417 287 291
    • (2002) Nature , vol.417 , pp. 287-291
    • Shaw, P.J.1    Tononi, G.2    Greenspan, R.J.3    Robinson, D.F.4
  • 134
    • 34249097203 scopus 로고    scopus 로고
    • Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression
    • SM Siepka SH Yoo J Park W Song V Kumar Y Hu C Lee JS Takahashi 2007 Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression Cell 129 1011 1023
    • (2007) Cell , vol.129 , pp. 1011-1023
    • Siepka, S.M.1    Yoo, S.H.2    Park, J.3    Song, W.4    Kumar, V.5    Hu, Y.6    Lee, C.7    Takahashi, J.S.8
  • 135
    • 14744304333 scopus 로고    scopus 로고
    • Central administration of transforming growth factor-alpha and neuregulin-1 suppress active behaviors and cause weight loss in hamsters
    • P Snodgrass-Belt JL Gilbert FC Davis 2005 Central administration of transforming growth factor-alpha and neuregulin-1 suppress active behaviors and cause weight loss in hamsters Brain Res 1038 171 182
    • (2005) Brain Res , vol.1038 , pp. 171-182
    • Snodgrass-Belt, P.1    Gilbert, J.L.2    Davis, F.C.3
  • 138
    • 7244242193 scopus 로고    scopus 로고
    • Coupled oscillators control morning and evening locomotor behaviour of Drosophila
    • D Stoleru Y Peng J Agosto M Rosbash 2004 Coupled oscillators control morning and evening locomotor behaviour of Drosophila Nature 431 862 868
    • (2004) Nature , vol.431 , pp. 862-868
    • Stoleru, D.1    Peng, Y.2    Agosto, J.3    Rosbash, M.4
  • 139
    • 27744493091 scopus 로고    scopus 로고
    • A resetting signal between Drosophila pacemakers synchronizes morning and evening activity
    • D Stoleru Y Peng P Nawathean M Rosbash 2005 A resetting signal between Drosophila pacemakers synchronizes morning and evening activity Nature 438 238 242
    • (2005) Nature , vol.438 , pp. 238-242
    • Stoleru, D.1    Peng, Y.2    Nawathean, P.3    Rosbash, M.4
  • 141
    • 0035448950 scopus 로고    scopus 로고
    • Multiple amidated neuropeptides are required for normal circadian locomotor rhythms in Drosophila
    • PH Taghert RS Hewes JH Park MA O'Brien M Han ME Peck 2001 Multiple amidated neuropeptides are required for normal circadian locomotor rhythms in Drosophila J Neurosci 21 6673 6686
    • (2001) J Neurosci , vol.21 , pp. 6673-6686
    • Taghert, P.H.1    Hewes, R.S.2    Park, J.H.3    O'Brien, M.A.4    Han, M.5    Peck, M.E.6
  • 143
    • 47049101810 scopus 로고    scopus 로고
    • Rhythmic E-box binding by CLK-CYC controls daily cycles in per and tim transcription and chromatin modifications
    • P Taylor PE Hardin 2008 Rhythmic E-box binding by CLK-CYC controls daily cycles in per and tim transcription and chromatin modifications Mol Cell Biol 28 4642 4652
    • (2008) Mol Cell Biol , vol.28 , pp. 4642-4652
    • Taylor, P.1    Hardin, P.E.2
  • 145
    • 33845999933 scopus 로고    scopus 로고
    • Hofbauer-Buchner eyelet affects circadian photosensitivity and coordinates TIM and per expression in Drosophila clock neurons
    • S Veleri D Rieger C Helfrich-Förster R Stanewsky 2007 Hofbauer-Buchner eyelet affects circadian photosensitivity and coordinates TIM and PER expression in Drosophila clock neurons J Biol Rhythms 22 29 42
    • (2007) J Biol Rhythms , vol.22 , pp. 29-42
    • Veleri, S.1    Rieger, D.2    Helfrich-Förster, C.3    Stanewsky, R.4
  • 146
    • 0034045931 scopus 로고    scopus 로고
    • Nuclear entry of the circadian regulator mPER1 is controlled by mammalian CASEIN KINASE i epsilon
    • E Vielhaber E Eide A Rivers ZH Gao DM Virshup 2000 Nuclear entry of the circadian regulator mPER1 is controlled by mammalian CASEIN KINASE I epsilon Mol Cell Biol 20 4888 4899
    • (2000) Mol Cell Biol , vol.20 , pp. 4888-4899
    • Vielhaber, E.1    Eide, E.2    Rivers, A.3    Gao, Z.H.4    Virshup, D.M.5
  • 147
    • 0032535338 scopus 로고    scopus 로고
    • CREB in the mouse SCN: A molecular interface coding the phase-adjusting stimuli light, glutamate, PACAP, and melatonin for clockwork access
    • C von Gall GE Duffield MH Hastings MD Kopp F Dehghani HW Korf JH Stehle 1998 CREB in the mouse SCN: a molecular interface coding the phase-adjusting stimuli light, glutamate, PACAP, and melatonin for clockwork access J Neurosci 18 10389 10397
    • (1998) J Neurosci , vol.18 , pp. 10389-10397
    • Von Gall, C.1    Duffield, G.E.2    Hastings, M.H.3    Kopp, M.D.4    Dehghani, F.5    Korf, H.W.6    Stehle, J.H.7
  • 149
    • 0345303671 scopus 로고    scopus 로고
    • A PERIOD inhibitor buffer introduces a delay mechanism for CLK/CYC-activated transcription
    • F Weber SA Kay 2003 A PERIOD inhibitor buffer introduces a delay mechanism for CLK/CYC-activated transcription FEBS Lett 555 341 345
    • (2003) FEBS Lett , vol.555 , pp. 341-345
    • Weber, F.1    Kay, S.A.2
  • 150
    • 33745101711 scopus 로고    scopus 로고
    • Second messenger and Ras/MAPK signalling pathways regulate CLOCK/CYCLE-dependent transcription
    • F Weber HC Hung C Maurer SA Kay 2006 Second messenger and Ras/MAPK signalling pathways regulate CLOCK/CYCLE-dependent transcription J Neurochem 98 248 257
    • (2006) J Neurochem , vol.98 , pp. 248-257
    • Weber, F.1    Hung, H.C.2    Maurer, C.3    Kay, S.A.4
  • 151
    • 0035929231 scopus 로고    scopus 로고
    • A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK
    • JA Williams HS Su A Bernards J Field A Sehgal 2001 A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK Science 293 2251 2256
    • (2001) Science , vol.293 , pp. 2251-2256
    • Williams, J.A.1    Su, H.S.2    Bernards, A.3    Field, J.4    Sehgal, A.5
  • 152
    • 40849134063 scopus 로고    scopus 로고
    • Electrical silencing of PDF neurons advances the phase of non-PDF clock neurons in Drosophila
    • Y Wu G Cao MN Nitabach 2008 Electrical silencing of PDF neurons advances the phase of non-PDF clock neurons in Drosophila J Biol Rhythms 23 117 128
    • (2008) J Biol Rhythms , vol.23 , pp. 117-128
    • Wu, Y.1    Cao, G.2    Nitabach, M.N.3
  • 155
    • 0037086535 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein
    • K Yagita F Tamanini M Yasuda JH Hoeijmakers GT van der Horst H Okamura 2002 Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein EMBO J 21 1301 1314
    • (2002) EMBO J , vol.21 , pp. 1301-1314
    • Yagita, K.1    Tamanini, F.2    Yasuda, M.3    Hoeijmakers, J.H.4    Van Der Horst, G.T.5    Okamura, H.6
  • 157
    • 0035458732 scopus 로고    scopus 로고
    • Time zones: A comparative genetics of circadian clocks
    • MW Young SA Kay 2001 Time zones: a comparative genetics of circadian clocks Nat Rev Genet 2 702 715
    • (2001) Nat Rev Genet , vol.2 , pp. 702-715
    • Young, M.W.1    Kay, S.A.2
  • 158
    • 33845910903 scopus 로고    scopus 로고
    • Circadian oscillators of Drosophila and mammals
    • W Yu PE Hardin 2006 Circadian oscillators of Drosophila and mammals J Cell Sci 119 4793 4795
    • (2006) J Cell Sci , vol.119 , pp. 4793-4795
    • Yu, W.1    Hardin, P.E.2
  • 159
    • 33645010948 scopus 로고    scopus 로고
    • PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription
    • W Yu H Zheng JH Houl B Dauwalder PE Hardin 2006 PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription Genes Dev 20 723 733
    • (2006) Genes Dev , vol.20 , pp. 723-733
    • Yu, W.1    Zheng, H.2    Houl, J.H.3    Dauwalder, B.4    Hardin, P.E.5
  • 160
    • 45149098327 scopus 로고    scopus 로고
    • Probing the relative importance of molecular oscillations in the circadian clock
    • X Zheng A Sehgal 2008 Probing the relative importance of molecular oscillations in the circadian clock Genetics 178 1147 1155
    • (2008) Genetics , vol.178 , pp. 1147-1155
    • Zheng, X.1    Sehgal, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.