Coupled oscillators control morning and evening locomotor behaviour of Drosophila

Nature

Volumn 431, Issue 7010, 2004, Pages 862-868

  Stoleru, Dan ^a   Peng, Ying ^a   Agosto, José ^a   Rosbash, Michael ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; LIVING SYSTEMS STUDIES; MUTAGENESIS; OSCILLATORS (MECHANICAL);

CIRCADIAN CLOCK; DROSOPHILA MELANOGASTER; MUTANTS;

PHYSIOLOGY;

NEUROPEPTIDE; PIGMENT DISPERSING FACTOR; UNCLASSIFIED DRUG;

BIOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN NERVE CELL; BRAIN REGION; CELL SPECIFICITY; CIRCADIAN RHYTHM; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EMBRYO; GENE MUTATION; LOCOMOTION; NONHUMAN; OSCILLATOR; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BEHAVIOR, ANIMAL; CIRCADIAN RHYTHM; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EYE PROTEINS; GENOTYPE; MOTOR ACTIVITY; NEURONS; NEUROPEPTIDES; PHOTORECEPTORS, INVERTEBRATE; RECEPTORS, G-PROTEIN-COUPLED; TIME FACTORS;

ANIMALIA; DROSOPHILA MELANOGASTER; MAMMALIA; MELANOGASTER;

EID: 7244242193     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02926     Document Type: Article

References (31)

1. Dunlap, J. C. Molecular bases for circadian clocks. Cell 96, 271-290 (1999).
2. Panda, S., Hogenesch, I. & Kay, S. Circadian rhythms from flies to human. Nature 417, 329-335 (2002).
3. Wheeler, D. A., Hamblen-Coyle, M. J., Dushay, M. S. & Hall, J. C. Behavior in light-dark cycles of Drosophila mutants that are arrhythmic, blind, or both. J. Biol. Rhythms 8, 67-94 (1993).
4. Helfrich-Forster, C. Differential control of morning and evening components in the activity rhythm of Drosophila melanogaster-sex specific differences suggest a different quality of activity. J. Biol. Rhythms 2, 135-154 (2000).
5. Hall, J. Genetics and molecular biology of rhythms in Drosophila and other insects. Adv. Genet. 48, 1-280 (2003).
6. Pittendrigh, C. S. & Daan, S. A functional analysis of circadian pacemakers in nocturnal rodents. V. Pacemaker structure: A clock for all seasons. J. Comp. Physiol. 106, 333-355 (1976).
7. Helfrich-Forster, C. The locomotor activity rhythm of Drosophila melanogaster is controlled by a dual oscillator system. J. Insect Physiol. 47, 877-887 (2001).
8. Kaneko, M. & Hall, J. C. Neuroanatomy of cells expressing clock genes in Drosophila: Transgenic manipulation of the period and timeless genes to mark the perikarya of circadian pacemaker neurons and their projections. J. Comp. Neural 422, 66-94 (2000).
9. Heifrich-Forster, C. The Period clock gene is expressed in centrai nervous system neurons which also produce a neuropeptidc that reveals the projections of circadian pacemaker cells within the brain of Drosophila melanogaster. Proc. Natl Acad. Sci. USA 92, 612-616 (1995).
10. Renn, S. C. P., Park, I. H., Rosbash, M., Hall, I. C. & Taghert, P. H. A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila. Cell 99, 791-802 (1999).
11. Park, J. H. et al. Differential regulation of circadian pacemaker output by separate clock genes in Drosophila. Proc. Natl Acad. Sci. USA 97, 3608-3613 (2000).
12. Peng, Y., Stoleru, D., Levine, J. D., Hall, J. C. & Rosbash, M. Drosophila free-running rhythms require intercellular communication. PLoS Biol. 1, E13 (2003).
13. Emery, P. et al. Drosophila CRY is a deep brain circadian photo receptor. Neuron 26, 493-504 (2000).
14. Klarsfeld, A. et al. Novel features of cryptochrome-mediated photoreception in the brain circadian clock of Drosophila. J. Neurosci. 24, 1468-1477 (2004).
15. Zhao, J. et al. Drosophila clock can generate ectopic circadian clocks. Cell 113, 755-766 (2003).
16. Rao, S., Lang, C., Levitan, E. S. & Deitcher, D. L. Visualization of neuropeptide expression, transport, and exocytosis in Drosophila tnelanogaster. J. Neurobiol 49, 159-172 (2001).
17. Blanchardon, E. et al. Defining the role of Drosophila lateral neurons in the control of circadian rhythms in motor activity and eciosion by targeted genetic ablation and PERIOD protein overexpression. Eur. J. Neurosci. 13, 871-888 (2001).
18. Veleri, S., Brandes, C., Helfrich-Forste, C., Half, J. C. & Stanewsky, R. A self-sustaining, light-entrainable circadian oscillator in the Drosophila brain. Curr. Biol. 13, 1758-1767 (2003).
19. Lee, T. & Luo, L. Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 22, 451-461 (1999).
20. Hardin, P. E., Hall, J. C. & Rosbash, M. Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels. Nature 343, 536-540 (1990).
21. Yang, Z, & Sehgal, A. Role of molecular oscillations in generating behavioral rhythms in Drosophila. Neuron 29, 453-467 (2001).
22. Lee, H. S., Billings, H. J. & Lehman, M. N. The suprachiasmatic nucleus: a clock of multiple components. J. Biol Rhythms 18, 435-449 (2003).
23. Jagota, A., de la Iglesia, H. O. & Schwartz, W. J. Morning and evening circadian oscillations in the suprachiasmatic nucleus in vitro. Nature Neurosci. 3, 372-376 (2000).
24. de la Iglesia, H. O., Meyer, J., Carpino, A. Jr & Schwartz, W. J. Antiphase oscillation of the left and right suprachiasmatic nuclei. Science 290, 799-801 (2000).
25. Yamaguchi, S. et al. Synchronization of cellular clocks in the suprachiasmatic nucleus. Science 302, 1408-1412 (2003).
26. Yoshii, T. et al. Drosophila cry(b) mutation reveals two circadian clocks that drive locomotor rhythm and have different responsiveness to light. J. Insect Physiol. 50, 479-488 (2004).
27. Harmar, A. et al. The VPAC(2) receptor is essential for circadian function in the mouse suprachiasmatic nuclei. Cell 109, 497-508 (2002).
28. Nitabach, M. N., Blau, J. & Holmes, T. C. Electrical silencing of Drosophila pacemaker neurons stops the free-running circadian clock. Cell 109, 485-495 (2002).
29. Levine, J., Funes, P., Dowse, H. & Hall, J. Signal analysis of behavioral and molecular cycles. BMC Neurosci. 3, 1 (2002).
30. Levine, J., Funes, P., Dowse, H. & Hall, J. Advanced analysis of a cryptochrome mutation's effects on the robustness and phase of molecular cycles in isolated peripheral tissues of Drosophila. BMC Neurosci. 3, 5 (2002).
31. Grinia, B., Chélot, E., Xia, R. & Rouyer, F. Morning and evening activity peaks are controlled by different clock neurons of the Drosophila brain. Nature doi:10.1038/nature02935 (this issue).