Light-dependent sequestration of TIMELESS by CRYPTOCHROME

Science

Volumn 285, Issue 5427, 1999, Pages 553-556

  Ceriani, M Fernanda ^a   Darlington, Thomas K ^a   Staknis, David ^b   Más, Paloma ^a   Petti, Allegra A ^b   Weitz, Charles J ^b   Kay, Steve A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; ARTICLE; CELLULAR DISTRIBUTION; CIRCADIAN RHYTHM; DROSOPHILA; LIGHT DARK CYCLE; NEGATIVE FEEDBACK; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RECEPTOR DENSITY;

ANIMALS; BIOLOGICAL CLOCKS; CELL LINE; CELL NUCLEUS; CIRCADIAN RHYTHM; CYTOPLASM; DARKNESS; DIMERIZATION; DROSOPHILA; DROSOPHILA PROTEINS; EYE PROTEINS; FLAVOPROTEINS; GREEN FLUORESCENT PROTEINS; INSECT PROTEINS; LIGHT; LUMINESCENT PROTEINS; MUTATION; NUCLEAR PROTEINS; PHOTORECEPTORS, INVERTEBRATE; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT FUSION PROTEINS; TRANSFECTION; YEASTS;

RUMEX;

EID: 0033597921     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.285.5427.553     Document Type: Article

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45. We thank K. Wager-Smith, A. Schinder, J. Hogenesch, D. Somers for critical reading of the manuscript and S. Harmer for helpful discussions; J. Sheen for the CFP clone (blue-sGFP-TYG-nosKS) (35), J. Blau, L. Saez, and M. Young for the TIM antibodies; R. Brent for the anti-LEXA antiserum; and J. Mosher and S. Crews for pRL-copia. This work was supported by National Institute of Mental Health grant MH-51573 and the NSF Center for Biological Timing (both to S.A.K.), Pew Foundation (as a fellowship to M.F.C.), and National Institute of Mental Health grant MH-59943 and the Harvard-Armenise Foundation for Advanced Scientific Research (both to C.J.W.).