Balance between DBT/CKIε kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 16, 2006, Pages 6178-6183

  Kim, Eun Young ^a   Edery, Isaac ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Circadian rhythms; Cycle; Period; Protein phosphatase 2A

Indexed keywords

CASEIN KINASE IEPSILON; DOUBLE TIME KINASE; HETERODIMER; ISOENZYME; PER1 PROTEIN; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOTRANSFERASE; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CLOCK; UNCLASSIFIED DRUG; CLK PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; ISOPROTEIN; NUCLEAR PROTEIN; PERIOD PROTEIN, INSECT;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CHROMATIN; CIRCADIAN RHYTHM; CONTROLLED STUDY; CYTOPLASM; DROSOPHILA; ENZYME ACTIVITY; GENE REPRESSION; IN VIVO STUDY; MOLECULAR CLOCK; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SEQUENCE HOMOLOGY; STOCHASTIC MODEL; TRANSACTIVATION; TRANSCRIPTION REGULATION; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE;

ANIMALIA; MAMMALIA; VERTEBRATA;

ANIMALS; CASEIN KINASE IEPSILON; CYTOPLASM; DROSOPHILA; DROSOPHILA PROTEINS; NUCLEAR PROTEINS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 33646591926     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0511215103     Document Type: Article

References (44)

1. Dunlap, J. C. (1999) Cell 96, 271-290.
2. Young, M. W. & Kay, S. A. (2001) Nat. Rev. Genet. 2, 702-715.
3. Edery, I. (1999) Chronobiol. Int. 16, 377-414.
4. Harms, E., Kivimae, S., Young, M. W. & Saez, L. (2004) J. Biol. Rhythms 19, 361-373.
5. Hirayama, J. & Sassone-Corsi, P. (2005) Curr. Opin. Genet. Dev. 15, 548-556.
6. Hardin, P. E. (2005) Curr. Biol. 15, R714-R722.
7. Cyran, S. A., Yiannoulos, G., Buchsbaum, A. M., Saez, L., Young, M. W. & Blau, J. (2005) J. Neurosci. 25, 5430-5437.
8. Kloss, B., Price, J. L., Saez, L., Blau, J., Rothenfluh, A., Wesley, C. S. & Young, M. W. (1998) Cell 94, 97-107.
9. Kloss, B., Rothenfluh, A., Young, M. W. & Saez, L. (2001) Neuron 30, 699-706.
10. Nawathean, P. & Rosbash, M. (2004) Mol. Cell 13, 213-223.
11. Preuss, F., Fan, J. Y., Kalive, M., Bao, S., Schuenemann, E., Bjes, E. S. & Price, J. L. (2004) Mol. Cell. Biol. 24, 886-898.
12. Price, J. L., Blau, J., Rothenfluh, A., Abodeely, M., Kloss, B. & Young, M. W. (1998) Cell 94, 83-95.
13. Sathyanarayanan, S., Zheng, X., Xiao, R. & Sehgal, A. (2004) Cell 116, 603-615.
14. Hardin, P. E. (2004) J. Biol. Rhythms 19, 348-360.
15. Bae, K., Lee, C., Hardin, P. E. & Edery, I. (2000) J. Neurosci. 20, 1746-1753.
16. Kim, E. Y., Bae, K., Ng, F. S., Glossop, N. R., Hardin, P. E. & Edery, I. (2002) Neuron 34, 69-81.
17. Lee, C., Bae, K. & Edery, I. (1998) Neuron 21, 857-867.
18. Bae, K., Lee, C., Sidote, D., Chuang, K. Y. & Edery, I. (1998) Mol. Cell. Biol. 18, 6142-6151.
19. Konopka, R. J. & Benzer, S. (1971) Proc. Natl. Acad. Sci. USA 68, 2112-2116.
20. Rothenfluh, A., Abodeely, M. & Young, M. W. (2000) Curr. Biol. 10, 1399-1402.
21. Eide, E. J. & Virshup, D. M. (2001) Chronobiol. Int. 18, 389-398.
22. Ko, H. W., Jiang, J. & Edery, I. (2002) Nature 420, 673-678.
23. Eide, E. J., Vielhaber, E. L., Hinz, W. A. & Virshup, D. M. (2002) J. Biol. Chem. 277, 17248-17254.
24. Akten, B., Jauch, E., Geneva, G. K., Kim, E. Y., Edery, I., Raabe, T. & Jackson, F. R. (2003) Nat. Neurosci. 6, 251-257.
25. Lin, J. M., Kilman, V. L., Keegan, K., Paddock, B., Emery-Le, M., Rosbash, M. & Allada, R. (2002) Nature 420, 816-820.
26. Martinek, S., Inonog, S., Manoukian, A. S. & Young, M. W. (2001) Cell 105, 769-779.
27. Edery, I., Zwiebel, L. J., Dembinska, M. E. & Rosbash, M. (1994) Proc. Natl. Acad. Sci. USA 91, 2260-2264.
28. Xu, Y., Padiath, Q. S., Shapiro, R. E., Jones, C. R., Wu, S. C., Saigoh, N., Saigoh, K., Ptacek, L. J. & Fu, Y. H. (2005) Nature 434, 640-644.
29. Forger, D. B. & Peskin, C. S. (2005) Proc. Natl. Acad. Sci. USA 102, 321-324.
30. Kondratov, R. V., Chernov, M. V., Kondratova, A. A., Gorbacheva, V. Y., Gudkov, A. V. & Antoch, M. P. (2003) Genes Dev. 17, 1921-1932.
31. Darlington, T. K., Wager-Smith, K., Ceriani, M. F., Staknis, D., Gekakis, N., Steeves, T. D., Weitz, C. J., Takahashi, J. S. & Kay, S. A. (1998) Science 280, 1599-1603.
32. He, Q. & Liu, Y. (2005) Genes Dev. 19, 2888-2899.
33. Schafmeier, T., Haase, A, Kaldi, K., Scholz, J., Fuchs, M. & Brunner, M. (2005) Cell 122, 235-246.
34. Lee, C., Etchegaray, J. P., Cagampang, F. R., Loudon, A. S. & Reppert, S. M. (2001) Cell 107, 855-867.
35. Lee, C., Bae, K. & Edery, I. (1999) Mol. Cell. Biol. 19, 5316-5325.
36. Etchegaray, J. P., Lee, C., Wade, P. A. & Reppert, S. M. (2003) Nature 421, 177-182.
37. Ishikawa, T., Hirayama, J., Kobayashi, Y. & Todo, T. (2002) Genes Cells 7, 1073-1086.
38. Holmberg, C. I., Tran, S. E., Eriksson, J. E. & Sistonen, L. (2002) Trends Biochem. Sci. 27, 619-627.
39. Allada, R., Kadener, S., Nandakumar, N. & Rosbash, M. (2003) EMBO J. 22, 3367-3375.
40. Allada, R., White, N. E., So, W. V., Hall, J. C. & Rosbash, M. (1998) Cell 93, 791-804.
41. Blau, J. & Young, M. W. (1999) Cell 99, 661-671.
42. Chang, D. C. & Reppert, S. M. (2003) Curr. Biol. 13, 758-762.
43. Hammond, S. M., Bernstein, E., Beach, D. & Hannon, G. J. (2000) Nature 404, 293-296.
44. Yu, W., Zheng, H., Houl, J. H., Dauwalder, B. & Hardin, P. E. (2006) Genes Dev. 20, 723-733.