A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila

Cell

Volumn 99, Issue 7, 1999, Pages 791-802

  Renn, Susan C P ^a   Park, Jae H ^c   Rosbash, Michael ^b   Hall, Jeffrey C ^c   Taghert, Paul H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRANDEIS UNIVERSITY   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

NEUROPEPTIDE;

ANIMAL BEHAVIOR; ARTICLE; CIRCADIAN RHYTHM; DROSOPHILA; GENE EXPRESSION; GENE MUTATION; HEART ARRHYTHMIA; LOCOMOTION; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 0033599009     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81676-1     Document Type: Article

References (45)

1. Anderson, S.L., and Kay, S.A. (1997). Light and circadian regulation of gene expression in plants. Adv. Genet. 35, 1-34.
2. 2 neuropeptide gene. J. Neurobiol. 38, 507-520.
3. Boer, G.J., van Esseeveldt, K.E., van der Geest, B.A., Duindam, H., and Rietveld, W.J. (1999). Vasopressin-deficient suprachiasmatic nucleus grafts re-instate circadian rhythmicity in suprachiasmatic nucleus lesioned arrhythmic rats. Neuroscience 89, 375-385.
4. Brand, A., and Perrimon, N. (1993). Targeting gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 410-415.
5. Cassone, V.M., and Menaker, M. (1983). Sympathetic regulation of chicken pineal rhythms. Brain Res. 272, 311-317.
6. Cassone, V.M., and Menaker, M. (1984). Is the avian circadian system a neuroendocrine loop? J. Exp. Zool. 232, 539-549.
7. Clem, R.J., Fechheimer, M., and Miller, L.K. (1991). Prevention of apoptosis by a baculovirus gene during infection of insect cells. Science 254, 1388-1390.
8. Dirckson, H., Zahnow, C.A., Gaus, G., Keller, R., Rao, K.R., and Riehm, J.P. (1987). The ultrastructure of nerve endings containing pigment-dispersing hormone (PDH) in crustacean sinus glands: identification by antiserum against synthetic PDH. Cell Tissue Res. 250, 377-387.
9. Dowse, H.B.,and Ringo, J.M. (1987). Further evidence that the circadian clock in Drosophila is a population of coupled ultradian period. J. Biol. Rhythms 2, 65-76.
10. Dunlap, J.C. (1999). Molecular bases for circadian clocks. Cell 96, 271-290.
11. Dushay, M.S., Rosbash, M., and Hall, J.C. (1989). The disconnected visual system mutations in Drosophila melanogaster drastically dis-rupt circadian rhythms. J. Biol. Rhythms 4, 1-27.
12. Dushay, M.S., Konopka, R.J., Orr, D., Greenacre, M.L., Kyriacou, C.P., Rosbash, M., and Hall, J.C. (1990). Phenotypic and genetic analysis of Clock, a new circadian rhythm mutant in Drosophila melanogaster. Genetics 125, 557-578.
13. Elekes, K., and Nässel, D.R. (1999). Pigment-dispersing hormone-like immunoreactive neurons in the central nervous system of the gastropods, Helix pomatia and Lymnaea stagnalis. Cell Tissue Res. 295, 339-348.
14. - mutants. J. Neurogenet. 3, 249-291.
15. Hamblen, M.J., White, N.E., Emery, P.T., Kaiser, K., and Hall, J.C. (1998). Molecular and behavioral analysis of four period mutants in Drosophila melanogaster encompassing extreme short, novel long, and unorthodox arrhythmic types. Genetics 149, 165-178.
16. Hamblen-Coyle, M.J., Konopka, R.J., Zweibel, L.J., Colot, H.V., Dowse, H.B., Rosbash, M., and Hall, J.C. (1989). A new mutation at the period locus of Drosophila melanogaster with some novel effects on circadian rhythms. J. Neurogenet. 5, 229-256.
17. Hamblen-Coyle, M.J., Wheeler, D.A., Rutila, J.E., Rosbash, M., and Hall, J.C. (1992). Behavior of period-altered circadian rhythm mutants of Drosophila in light:dark cycles (Diptera: Drosophilidae). J. Insect Behav. 5, 417-446.
18. Harrington, M.E., Hoque, S., Hall, A., Golombek, D., and Biello, S. (1999). Pituitary adenylate cyclase activating peptide phase shifts circadian rhythms in a manner similar to light. J. Neurosci. 19, 6637-6642.
19. Helfrich-Förster, C. (1995). The period clock gene is expressed in central nervous system neurons which also produce a neuropeptide that reveals the projections of circadian pacemaker cells within the brain of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 92, 612-616.
20. Helfrich-Förster, C. (1997). Development of pigment-dispersing hormone immunoreactive neurons in the nervous system of Drosophila melanogaster. J. Comp. Neurol. 380, 335-354.
21. Helfrich-Förster, C. (1998). Robust circadian rhythmicity of Drosoph ila melanogaster requires the presence of lateral neurons: a brainbehavioral study of disconnected mutants. J. Comp. Physiol. A 182, 435-453.
22. Helfrich-Förster, C., Stengl, M., and Homberg, U. (1998). Organization of the circadian system in insects. Chronobiol. Int. 15, 567-594.
23. Homberg, U., Würden, S., Dirksen, H., and Rao, K.R. (1991). Comparative anatomy of pigment-dispersing hormone-immunoreactive neurons in the brain of orthopteroid insects. Cell Tissue Res. 266, 343-357.
24. Inouye, S.-l.T. (1996). Circadian rhythms of neuropeptides in the suprachiasmatic nucleus. Prog. Brain Res. 111, 75-90.
25. Jin,X., Shearman, L.P..Weaver, D.R., Zylka, M.J., DeVries, G.J., and Reppert, S.M. (1999). A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock. Cell 96, 57-68.
26. Kaneko, M. (1998). Neural substrates of Drosophila rhythms revealed by mutants and molecular manipulations. Curr. Opin. Neurobiol. 8, 652-658.
27. Kaneko, M., Helfrich-Förster, C., and Hall, J.C. (1997). Spatial and temporal expression of the period and timeless genes in the developing nervous system of Drosophila: newly identified pacemaker candidates and novel features of clock gene product cycling. J. Neurosci. 17, 6745-6760.
28. Klemenz, R., Weber, U., and Gehring, W.J. (1987). The white gene as a marker in a new P-element vector for gene transfer in Drosophila. Nucleic Acids Res. 15, 3947-3959.
29. Li, X., Borjigin, J., and Snyder, S.H. (1998). Molecular rhythms in the pineal gland. Curr. Opin. Neurobiol. 8, 648-651.
30. Lopez-Molina, L, Conquet, F., Dubois-Dauphin, M., and Schibler, U. (1997). The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior. EMBO J. 16, 6762-6771.
31. Loros, J.J. (1998). Time at the end of the millennium: the Neurospora clock. Curr. Opin. Microbiol. 1, 698-706.
32. McNabb, S.L. Baker, J.D., Agapite, J., Steller, H., Riddiford, L.M., and Truman, J.W. (1997). Disruption of a behavioral sequence by targeted death of peptidergic neurons in Drosophila. Neuron 79, 813-823.
33. Menaker, M., and Zimmerman, N. (1976). Role of the pineal in the circadian system of birds. Am. Zool. 16, 45-55.
34. Nässel, D.R., Shiga, S., Wikstrand, E.M., and Rao, K.R. (1991). Pigment-dispersing hormone-immunoreactive neurons and their relation to serotonergic neurons in the blowfly and cockroach visual system. Cell Tissue Res. 266, 511-523.
35. Nässel, D.R., Shiga, S., Mohrherr, C.J., and Rao, K.R. (1993). Pigment-dispersing hormone-like peptide in the nervous system of the flies Phormia and Drosophila: immunocytochemistry and partial characterization. J. Comp. Neurol. 331, 183-198.
36. Park, J.H., and Hall, J.C. (1998). Isolation and chronobiological analysis of a neuropeptide pigment-dispersing factor gene in Drosophila melanogaster. J. Biol. Rhythms 13, 219-228.
37. Petri, B., and Stengl, M. (1997). Pigment-dispersing hormone shifts the phase of the circadian pacemaker of the cockroach Leucophaea maderae. J. Neurosci. 17, 4087-4093.
38. Pyza, E., and Meinertzhagen, I.A. (1996). Neurotransmitters regulate rhythmic size changes amongst cells in the fly's optic lobe. J. Comp. Physiol. A 178, 33-45.
39. Rao, K.R., and Riehm, J.P. (1993). Pigment-dispersing hormones. Ann. N.Y. Acad. Sci. 680, 78-88.
40. Schneider, L.E., Roberts, M.S., and Taghert, P.H. (1993). Cell type-specific transcriptional regulation of the Drosophila FMRFamide neuropeptide gene. Neuron 10, 279-291.
41. Sokolove, P.G., and Bushell, W.N. (1978). The chi square periodogram: its utility for analysis of circadian rhythms. J. Theor. Biol. 72, 131-160.
42. Van Gelder, R.N., and Krasnow, M.A. (1996). A novel circadianly expressed Drosophila melanogaster gene dependent on the period gene for its rhythmic expression. EMBO J. 15, 1625-1631.
43. Weaver, D.R. (1998). The suprachiasmatic nucleus: a 25-year retrospective. J. Biol. Rhythms 2, 100-112.
44. Wheeler, D.A., Hamblen-Coyle, M.J., Dushay, M.S., and Hall, J.C. (1993). Behavior in light-dark cycles of Drosophila mutants that are arrhythmic, blind, or both. J. Biol. Rhythms 8, 67-94.
45. Zhou, L, Schnitzler, A., Agapite, J., Schwartz, L.M., Steller, H., and Nambu, J.R. (1997). Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosoph-ila central nervous system midline cells. Proc. Natl. Acad. Sci. USA 94, 5131-5136.