Phosphorylation of PERIOD is influenced by cycling physical associations of DOUBLE-TIME, PERIOD, and TIMELESS in the Drosophila clock

Neuron

Volumn 30, Issue 3, 2001, Pages 699-706

  Kloss, Brian ^a   Rothenfluh, Adrian ^a   Young, Michael W ^a   Saez, Lino ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE I; DOUBLE TIME PROTEIN; MESSENGER RNA; PERIOD PROTEIN; PROTEIN; RNA; TIMELESS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ASSOCIATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CIRCADIAN RHYTHM; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; DROSOPHILA; GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION;

EID: 0034964474     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(01)00320-8     Document Type: Article

References (31)

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2. Autoinhibition of casein kinase Iε (CKIε) is relieved by protein phosphatases and limited proteolysis
3. Temporally regulated nuclear entry of the Drosophila Period protein contributes to the circadian clock
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5. Temporal phosphorylation of the Drosophila Period protein
6. Role of COOH-terminal phosphorylation in the regulation of casein kinase Iδ
7. Regulation of the Drosophila protein Timeless suggests a mechanism for resetting the circadian clock by light
8. The Drosophila clock gene double-time encodes a protein closely related to human Casein kinase Iε
9. Epitope tagging and protein surveillance
10. The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex
11. Resetting the Drosophila clock by photic regulation of PER and a PER-TIM complex
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14. Light-induced degradation of TIMELESS and entrainment of the Drosophila circadian clock
15. Independent photoreceptive circadian clocks throughout Drosophila
16. Double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation
17. Suppression of PERIOD protein abundance and circadian cycling by the Drosophila clock mutation timeless
18. A TIMELESS-independent function for PERIOD proteins in the Drosophila clock
19. Isolation and analysis of six timeless alleles that cause short- or long-period circadian rhythms in Drosophila
20. Short-period mutations of per affect a double-time-dependent step in the Drosophila circadian clock
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22. Regulation of nuclear entry of the Drosophila clock proteins Period and Timeless
23. Time flies for Drosophila
24. Two novel double-time mutants alter circadian properties and eliminate the delay between RNA and protein in Drosophila
25. An hPer2 phosphorylation site mutation in familial advanced sleep-phase syndrome
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27. Block in nuclear localization of Period protein by a second clock mutation, timeless
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29. A light-entrainment mechanism for the Drosophila circadian clock
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31. Double-time is identical to discs overgrown, which is required for cell survival, proliferation and growth arrest in Drosophila imaginal discs