Model of human aging: Recent findings on Werner's and Hutchinson-Gilford progeria syndromes

Clinical Interventions in Aging

Volumn 3, Issue 3, 2008, Pages 431-444

  Ding, Shian Ling ^a   Shen, Chen Yang ^b,c  

^a Kang Ning Junior College of Medical Care and Management   (Taiwan)

^b ACADEMIA SINICA   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Human aging; Hutchinson Gilford Progeria syndrome; Werner syndrome

Indexed keywords

ADENOSINE TRIPHOSPHATE; BLOOM SYNDROME HELICASE; CONNECTIVE TISSUE GROWTH FACTOR; CYCLINE; CYTIDINE; DNA; DNA TOPOISOMERASE; EXONUCLEASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GUANOSINE; HELICASE; LAMIN A; LAMIN C; NIBRIN; POL PROTEIN; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN P21; PROTEIN P53; RAD51 PROTEIN; RAD52 PROTEIN; REPLICATION FACTOR A; SERINE; TELOMERASE REVERSE TRANSCRIPTASE; TELOMERIC REPEAT BINDING FACTOR 2; THYMIDINE; WERNER SYNDROME PROTEIN;

AGING; APOPTOSIS; CARBOXY TERMINAL SEQUENCE; CHROMOSOME ABERRATION; DNA DAMAGE; DNA DEGRADATION; DNA METABOLISM; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; DNA STRAND; DNA TRANSCRIPTION; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; ENZYME ACTIVITY; EXCISION REPAIR; GENE DELETION; GENE FUNCTION; GENE MUTATION; GENE OVEREXPRESSION; GENOMIC INSTABILITY; HUMAN; IONIZING RADIATION; MOLECULAR DYNAMICS; NUCLEIC ACID BASE SUBSTITUTION; OXIDATIVE STRESS; PREMATURE AGING; PROGERIA; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; REVIEW; SUMOYLATION; TELOMERE; WERNER SYNDROME;

AGED; AGING; DNA; EXODEOXYRIBONUCLEASES; HUMANS; LAMIN TYPE A; LIPODYSTROPHY; MODELS, MOLECULAR; MUTATION; PROGERIA; RECQ HELICASES; WERNER SYNDROME;

EID: 54949154104     PISSN: 11769092     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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