Werner syndrome helicase contains a 5'→3' exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding

Nucleic Acids Research

Volumn 27, Issue 11, 1999, Pages 2361-2368

  Suzuki, Noriyuki ^a   Shiratori, Miwa ^a   Goto, Makoto ^a,b   Furuichi, Yasuhiro ^a  

^a AGENE Research Institute   (Japan)

^b Toshima ku   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMINO ACID; DNA; DOUBLE STRANDED DNA; EXONUCLEASE; HELICASE; HETERODUPLEX; MONOCLONAL ANTIBODY; NUCLEOTIDE; RNA; SINGLE STRANDED DNA;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BACULOVIRUS; CONTROLLED STUDY; DELETION MUTANT; DNA REPAIR; DNA REPLICATION; DNA RNA HYBRIDIZATION; DNA TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; WERNER SYNDROME;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; DNA; DNA HELICASES; EXODEOXYRIBONUCLEASE V; EXODEOXYRIBONUCLEASES; HUMANS; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID HETERODUPLEXES; PRECIPITIN TESTS; RECQ HELICASES; RNA; SPODOPTERA; WERNER SYNDROME;

ANIMALIA; UNIDENTIFIED BACULOVIRUS;

EID: 0033151822     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/27.11.2361     Document Type: Article

References (40)

1. Werner,O. (1904) Doctoral dissertation, Kiel University, Kiel, Germany.
2. Epstein,C.J., Martin,G.M., Schultz,A.L. and Motulsky,A.G. (1966) Medicine, 45, 177-221.
3. Martin,G.M. (1978) In Bergsma,D. and Harrison,D.E. (eds), Genetic Effects on Aging. Alan R. Liss, New York, NY, pp. 3-39.
4. Goto,M. (1997) Mech. Ageing Dev., 98, 239-254.
5. Goto,M., Miller,R.W., Ishikawa,Y. and Sugano,H. (1996) Cancer Epidemiol. Biomarkers Prev., 5, 239-246.
6. Salk,D., Bryant,E., Hoehn,H., Johnston,P. and Martin,G.M. (1985) Adv. Exp. Med. Biol., 190, 305-311.
7. Tahara,H., Tokutake,Y., Maeda,S., Kataoka,H., Watanabe,T., Satoh,M., Matsumoto,T., Sugawara,M., Ide,T., Goto,M., Furuichi,Y. and Sugimoto,M. (1997) Oncogene, 15, 1911-1920.
8. Yu,C.E., Oshima,J., Fu,Y.H., Wijsman,E.M., Hisama,F., Alisch,R., Matthews,S., Nakura,J., Miki,T., Ouais,S., Martin,G.M., Mulligan,J., and Schellenberg,G.D. (1996) Science, 272, 258-262.
9. Nakayama,K., Irino,N. and Nakayama,H. (1985) Mol. Gen. Genet., 200, 266-271.
10. Seki,M., Yanagisawa,J., Kohda,T., Sonoyama,T., Ui,M. and Enomoto,T. (1994) J. Biochem., 115, 523-531.
11. Ellis,N.A., Groden,J., Ye,T.Z., Straughen,J., Lennon,D.J., Ciocci,S., Proytcheva,M. and German,J. (1995) Cell, 83, 655-666.
12. Kitao,S., Ohsugi,I., Ichikawa,K., Goto,M., Furuichi,Y. and Shimamoto,A. (1998) Genomics, 54, 443-452.
13. Kitao,S., Shimamoto,A., Goto,M., Miller,R.W., Smithson,W.A., Lindor,N.M. and Furuichi,Y. (1999) Nature Genet., 22, 82-84.
14. Gangloff,S., McDonald,J.P., Bendixen,C., Arthur,L. and Rothstein,R. (1994) Mol. Cell. Biol., 14, 8391-8398.
15. Watt,P.M., Louis,E.J., Borts,R.H. and Hickson,I.D. (1995) Cell, 81, 253-260.
16. Stewart,E., Chapman,C.R., Al-Khodairy,F., Carr,A.M. and Enoch,T. (1997) EMBO J., 16, 2682-2692.
17. Lohman,T.M. (1993) J. Biol. Chem., 268, 2269-2272.
18. Kusano,K., Sunohara,Y., Takahashi,N., Yoshikura,H. and Kobayashi,I. (1994) Proc. Natl Acad. Sci. USA, 91, 1173-1177.
19. Hanada,K., Ukita,T., Kohno,Y., Saito,K., Kato,J. and Ikeda,H. (1997) Proc. Natl Acad. Sci. USA, 94, 3860-3865.
20. Yamagata,K., Kato,J., Shimamoto,A., Goto,M., Furuichi,Y. and Ikeda,H. (1998) Proc. Natl Acad. Sci. USA, 95, 8733-8738.
21. Suzuki,N., Shimamoto,A., Imamura,O., Kuromitsu,J., Kitao,S., Goto,M. and Furuichi,Y. (1997) Nucleic Acids Res., 25, 2973-2978.
22. Gray,M.D., Shen,J.C., Kamath-Loeb,A.S., Blank,A., Sopher,B.L., Martin,G.M., Oshima,J. and Loeb,L.A. (1997) Nature Genet., 17, 100-103.
23. Matsumoto,J., Shimamoto,A., Goto,M. and Furuichi,Y. (1997) Nature Genet., 16, 335-336.
24. Matsumoto, T., Imamura,O., Goto,M. and Furuichi,Y. (1998) Int. J. Mol. Med., 1, 71-76.
25. Shiratori,M., Sakamoto,S., Suzuki,N., Tokutake,Y., Kawabe,Y., Enomoto,T., Sugimoto,M., Goto,M., Matsumoto,T. and Furuichi,Y. (1999) J. Cell Biol., 144, 1-9.
26. Mushegian,A.R., Bassett,D.E.,Jr, Boguski,M.S., Bork,P. and Koonin,E.V. (1997) Proc. Natl Acad. Sci. USA, 94, 5831-5836.
27. Mian,I.S.(1997) Nucleic Acids Res., 25, 3187-3195.
28. Moser,M.J., Holley,W.R., Chatterjee,A. and Mian.I.S. (1997) Nucleic Acids Res., 25, 5110-5118.
29. Morozov,V., Mushegian,A.R., Koonin,E.V. and Bork,P. (1997) Trends Biochem. Sci., 22, 417-418.
30. Huang,S., Li.B., Gray,M.D., Oshima,J., Mian.I.S. and Campisi,J. (1998) Nature Genet., 20, 114-116.
31. Shen,J.C., Gray,M.D., Oshima,J., Kamath-Loeb,A.S., Fry,M. and Loeb,L.A. (1998) J. Biol. Chem., 273, 34139-34144.
32. Kamath-Loeb,A.S., Shen,J.C., Loeb,L.A. and Fry,M. (1998) J. Biol. Chem., 273, 34145-34150.
33. England,T.E. and Uhlenbeck,O.C. (1978) Nature, 275, 560-561.
34. Mummenbrauer,T., Janus,F., Muller,B., Wiesmuller,L., Deppert,W. and Grosse,F. (1996) Cell, 85, 1089-1099.
35. Furuichi,Y., Morgan,M., Muthukrishnan,S. and Shatkin,A.J. (1975) Proc. Natl Acad. Sci. USA, 72, 362-366.
36. Dixon,D.A., Churchill,J.J. and Kowalczykowski,S.C. (1994) Proc. Natl Acad. Sci. USA, 91, 2980-2984.
37. Bennett,R.J., Sharp,J.A. and Wang,J.C. (1998) J. Biol. Chem., 273, 9644-9650
38. Marciniak,R.A., Lombard,D.B., Johnson,F.B. and Guarente,L. (1998) Proc. Natl Acad. Sci. USA, 95, 6887-6892.
39. Gray,M.D., Wang,L., Youssoufian,H., Martin,G.M. and Oshima,J. (1998) Exp. Cell Res., 242, 487-494.
40. Fukuchi,K., Martin,G.M. and Monnat,R.J.,Jr (1989) Proc. Natl Acad. Sci. USA, 86, 5893-5897.