Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2

Molecular Cell

Volumn 8, Issue 2, 2001, Pages 351-361

  Fairall, Louise ^a   Chapman, Lynda ^a   Moss, Heidi ^b   De Lange, Titia ^b   Rhodes, Daniela ^a,c  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b ROCKEFELLER UNIVERSITY   (United States)

^c 011 44 1223 213556 ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME PROTEIN; DNA BINDING PROTEIN; FUNGAL PROTEIN; TELOMERIC REPEAT BINDING FACTOR 1; TELOMERIC REPEAT BINDING FACTOR 2; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CHROMOSOME MUTATION; CONTROLLED STUDY; CRYSTALLOGRAPHY; DIMERIZATION; DNA BINDING; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; TELOMERE; YEAST;

SCHIZOSACCHAROMYCES POMBE; VERTEBRATA;

EID: 0034847376     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00321-5     Document Type: Article

References (52)

1. 1 ATPase
2. Structure of ColE1 Rop protein at 1.7Å resolution
3. Amino acid substitution during functionally constrained divergent evolution of protein sequences
4. TRF1 is a dimer and bends telomeric DNA
5. TRF1 binds a bipartite telomeric site with extreme spatial flexibility
6. Comparison of the human and mouse genes encoding the telomeric protein, TRF1: Chromosomal localization, expression and conserved protein domains
7. Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
8. Telomerase activation in mouse mammary tumors: Lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation
9. Crystallography and NMR system: A new software suite for macromolecular structure determination
10. The CCP4 suite: Programs for protein crystallography
11. A human telomeric protein
12. Regulation of telomere length and function by a Myb-domain protein in fission yeast
13. Structure and variability of human chromosome ends
14. The fission yeast Taz1 protein protects chromosomes from Ku-dependent end-to-end fusions
15. TRF1 promotes parallel pairing of telomeric tracts in vitro
16. Mammalian telomeres end in a large duplex loop
17. SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
18. Protein structure comparison by alignment of distance matrices (Dali 2.0)
19. Improved methods for building protein models in electron density maps and the location of errors in these models
20. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
21. TIN2, a new regulator of telomere length in human cells
22. Recognition of telomeric DNA
23. The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA
24. Sequence-specific DNA recognition by the myb-like domain of the human telomere binding protein TRF1: A model for the protein-DNA complex
25. Molscript: A program to produce both detailed and schematic plots of protein structures
26. Advances in MIR and MAD phasing: Maximum-likelihood refinement in a graphical environment, with SHARP
27. Recent changes to the MOSFLM package for processing film and image plate data
28. Identification of human Rap1: Implications for telomere evolution
29. DNA ends: Maintenance of chromosome termini versus repair of double strand breaks
30. Rap1p and telomere length regulation in yeast
31. A protein-counting mechanism for telomere length regulation in yeast
32. Telomeres and their control
33. T-loops at trypanosome telomeres
34. Telomeres of polytene chromosomes in a ciliated protozoan terminate in duplex DNA loops
35. Two modes of survival of fission yeast without telomerase
36. A novel mechanism of PXA anchoring by solution structures of anchoring complex
37. Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe
38. Solution structure of the DNA-binding domain of human telomeric protein, hTRF1
39. Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices
40. Treatment of MAD data as a special case of MIR
41. Crystal structure of the vesical transport protein Sec17: Implications for SNAP function in SNARE complex disassembly
42. Combining evolutionary information and neural networks to predict protein secondary structure
43. Tankyrase promotes telomere elongation in human cells
44. Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
45. Control of human telomere length by TRF1 and TRF2
46. Sequence-specific binding of Taz1 dimers to fission yeast telomeric DNA
47. Correlated phasing of multiple isomorphous replacement data
48. Control of telomere length by the human telomeric protein TRF1
49. TRF2 protects human telomeres from end-to-end fusions
50. Peptide substrates for assaying glycogen synthase kinase-3 in crude cell extracts
51. A mammalian factor that binds telomeric TTAGGG repeats in vitro
52. Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres