The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: Implications for WRN function

DNA Repair

Volumn 3, Issue 6, 2004, Pages 629-638

  Blank, A ^a   Bobola, Michael S ^b,c   Gold, Barry ^d   Varadarajan, Sridhar ^d   Kolstoe, Douglas D ^b   Meade, Elizabeth H ^b   Rabinovitch, Peter S ^a   Loeb, Lawrence A ^a   Silber, John R ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

3 MAG; 3 methyladenine DNA glycosylase; Alkylating agents; Antisense; antisense oligonucleotides; ASO; Cancer; DNA damage; DNA repair; HU; hydroxyurea; Me Lex; methyl lexitropsin; MGMT; N3 meA; N3 methyladenine; O6 methylguanine DNA methyltransferase

Indexed keywords

3 METHYLADENINE; 4 NITROQUINOLINE 1 OXIDE; 6 O METHYLGUANINE; ALKYLATING AGENT; CAMPTOTHECIN; CYTOTOXIC AGENT; HYDROXYUREA; METHYL LEXITROPSIN; UNCLASSIFIED DRUG; WERNER SYNDROME PROTEIN;

ARTICLE; CELL DIVISION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION;

4-NITROQUINOLINE-1-OXIDE; ADENINE; ALKYLATING AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CAMPTOTHECIN; CARCINOGENS; CELLS, CULTURED; DNA DAMAGE; DNA HELICASES; DNA REPLICATION; DRUG RESISTANCE; FIBROBLASTS; GLIOMA; GUANINE; HUMANS; HYDROXYUREA; NETROPSIN; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; OLIGONUCLEOTIDES, ANTISENSE; RECQ HELICASES; WERNER SYNDROME;

EID: 2342569002     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2004.02.003     Document Type: Article

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