A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 22, 1998, Pages 13097-13102

  Lebel, Michel ^a   Leder, Philip ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; HELICASE;

ANIMAL EXPERIMENT; ARTICLE; AUTOSOMAL RECESSIVE INHERITANCE; CELL PROLIFERATION; CENTRIFUGATION; CHROMOSOME 8; COMPLEX FORMATION; DNA REPLICATION; FIBROBLAST; GENE DELETION; GENE MAPPING; MOLECULAR CLONING; MOUSE; NONHUMAN; PHENOTYPE; PREMATURE AGING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; SYNTENY; WERNER SYNDROME;

ANIMALS; BASE SEQUENCE; CAMPTOTHECIN; CELL DIVISION; CELLS, CULTURED; CHIMERA; CHROMOSOME MAPPING; CLONING, MOLECULAR; CROSSES, GENETIC; DNA HELICASES; DNA PRIMERS; FEMALE; FETAL DEATH; HOMOZYGOTE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MURIDAE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RECOMBINATION, GENETIC; SEQUENCE DELETION; STEM CELLS; TRANSFECTION; WERNER SYNDROME;

ANIMALIA; MURINAE;

EID: 0032573157     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.22.13097     Document Type: Article

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