Drug development based on the metals hypothesis of Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 15, Issue 2, 2008, Pages 223-240

  Bush, Ashley I ^a,b,c  

^a FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alzheimer's disease; Amyloid ; Clinical trials; Copper; Iron; Metals; Oligomer; Oxidation; Zinc

Indexed keywords

1,1 XYLYL BIS 1,4,8,11 TETRAAZACYCLOTETRADECANE; AMYLOID BETA PROTEIN; CHELATING AGENT; CLIOQUINOL; COPPER; DEFEROXAMINE; DEFEROXAMINE MESYLATE; DP 109; JKL 169; PBT 2; PENICILLAMINE; PLACEBO; QUINOLINE DERIVATIVE; TAU PROTEIN; TETRADECANE; UNCLASSIFIED DRUG; ZINC;

ABSENCE OF SIDE EFFECTS; AGING; ALZHEIMER DISEASE; BRAIN CORTEX; CHELATION; CLINICAL TRIAL; COLOR VISION DEFECT; DRUG DEVELOPMENT; DRUG DOSE ESCALATION; GOUT; HEART ARREST; HOMEOSTASIS; HUMAN; LEUKOPENIA; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 54249103057     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2008-15208     Document Type: Review

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