BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper

Journal of Biological Chemistry

Volumn 280, Issue 18, 2005, Pages 17930-17937

  Angeletti, Barbara ^a,e   Waldron, Kevin J ^b   Freeman, Katie B ^c   Bawagan, Hinayana ^c   Hussain, Ishrut ^a   Miller, Christoplier C J ^d   Lau, Kwok Fai ^d   Tennan, Maria E ^d   Dennison, Christopher ^b   Robinson, Nigel J ^b   Dingwall, Colin ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c GLAXOSMITHKLINE   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMS; BRAIN; COPPER; DEPOSITION; MEMBRANES;

CYSTEINE; EXTRACELLULAR DOMAIN; HOMEOSTATIS;

ENZYMES;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 1; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; CYSTEINE; IRON; UNCLASSIFIED DRUG; ZINC; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; CCS PROTEIN, RAT; CHAPERONE; PROTEINASE; SECRETASE; SUPEROXIDE DISMUTASE;

ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; GENE OVEREXPRESSION; HOMEOSTASIS; HUMAN; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; SENILE PLAQUE; ANIMAL; BINDING SITE; BIOSYNTHESIS; CYTOPLASM; ENZYMOLOGY; GENETICS; METABOLISM; PROTEIN TERTIARY STRUCTURE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BINDING SITES; COPPER; CYTOPLASM; ENDOPEPTIDASES; HUMANS; MOLECULAR CHAPERONES; PROTEIN STRUCTURE, TERTIARY; RATS; SUPEROXIDE DISMUTASE;

EID: 24044479679     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412034200     Document Type: Article

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