Oxidation of cholesterol by amyloid precursor protein and β-amyloid peptide

Journal of Biological Chemistry

Volumn 280, Issue 8, 2005, Pages 7377-7387

  Nelson, Thomas J ^a   Alkon, Daniel L ^a  

^a Blanchette Rockefeller Neurosciences Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; COPPER; DISEASES; ENZYME INHIBITION; ENZYMES; HYDROGEN PEROXIDE; MOLECULAR BIOLOGY; OXIDATION; POLYPEPTIDES; PROTEINS; STOICHIOMETRY;

ALZHEIMER'S DISEASE (AD); AMYLOID PRECURSOR PROTEIN (APP); NEUROTOXIC PEPTIDES; SYNAPTOGENESIS;

CHOLESTEROL;

7BETA HYDROXYCHOLESTEROL; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CHOLESTEROL; COPPER; GAMMA SECRETASE; OXYSTEROL; PROTEIN KINASE C ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; CHOLESTEROL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HIPPOCAMPUS; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; STOICHIOMETRY; SYNAPSE; SYNAPTOGENESIS;

ADAM PROTEINS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BRAIN; CELL LINE; CHOLESTEROL; ENDOPEPTIDASES; GUINEA PIGS; HIPPOCAMPUS; HUMANS; HYDROXYCHOLESTEROLS; KINETICS; METALLOENDOPEPTIDASES; NEURONS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS;

EID: 14844304305     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409071200     Document Type: Article

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