Metal swap between Zn7-metallothionein-3 and amyloid-β-Cu protects against amyloid-β toxicity

Nature Chemical Biology

Volumn 4, Issue 6, 2008, Pages 366-372

  Meloni, Gabriele ^a   Sonois, Vanessa ^b,c   Delaine, Tamara ^b   Guilloreau, Luc ^b   Gillet, Audrey ^b   Teissié, Justin ^c   Faller, Peter ^b   Vašák, Milan ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

^c INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40] COPPER; COPPER ION; METALLOPROTEIN; REACTIVE OXYGEN METABOLITE; ZINC7 METALLOTHIONEIN 3; AMYLOID BETA PROTEIN[1-40]; COPPER; METALLOTHIONEIN; ORGANOMETALLIC COMPOUND; PEPTIDE FRAGMENT; ZINC;

ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; DOWN REGULATION; HUMAN; HUMAN CELL; METAL BINDING; NERVE CELL CULTURE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CIRCULAR DICHROISM; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; NERVE CELL; SOLUBILITY;

AMYLOID BETA-PROTEIN; CELL SURVIVAL; CIRCULAR DICHROISM; COPPER; HUMANS; METALLOTHIONEIN; NEURONS; ORGANOMETALLIC COMPOUNDS; PEPTIDE FRAGMENTS; REACTIVE OXYGEN SPECIES; SOLUBILITY; TUMOR CELLS, CULTURED; ZINC;

EID: 43749104422     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.89     Document Type: Article

References (48)